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Acta Physiologica Congress

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Acta Physiologica 2009; Volume 195, Supplement 669
The 88th Annual Meeting of The German Physiological Society
3/22/2009-3/25/2009
Giessen, Germany

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    S
    Sabelhaus C.- Inhibition of Na+/H+ exchangers protects hippocampal slices from oxygen-glucose-deprivation induced injury
    Saftig P.- Renal pathophysiology in mice deficient for the tetraspaninCD63/LIMP-1
    Sahoo N.- Thiol-dependent modulation of human EAG1 potassium channels
     - Tuesday, March 24, Hall 4Oral SessionPotassium channelsChairpersons: R. Bhring (Hamburg)S. H. Heinemann (Jena) EAG genes in Danio rerio coding for functional potassium channels
    Sall Jensen M.- Long-term depression of pain perception in man affects peripheral receptive fields
    Salling H.- HL-1mouse cardiomyocyte death after simulated ischemia and reperfusion is dependent on pHo: Roles of the Na+/H+ exchanger NHE1, and the Ca2+-independentphospholipase A2 PLA2-VI
    Samakovlis C.- The LEM-domain protein MAN1 is required for presynaptic function at the drosophila neuromuscular junction
    Sandtner W.- Conformational stability of the domain IV S6 segment of the voltage-gated Na channel as assessed by single- and double mutant perturbation analysis
    Sandulache D.- Monday, March 23, Audimax, Poster Area CPoster Session: Kidney IModerators: W. Neuhofer (Mnchen)W. H. Castrop (Regensburg) Renal function of PDK1 hypomorphic mice
    Santani D.- Involvement of PI3K/AKT pathway in the hypoglycemic effects of saponins from Helicteres isora
    Sargin S.- Effects of modified 1-integrin expression on pH-dependent adhesion and migration of human melanoma cells
     - The molecular compass for macrophage chemotaxis
    Sartor F.- Influence of a combined low-carbohydrate high intensity interval training intervention on insulin sensitivity, blood lipids and whole body metabolism in obese sedentary individuals
    Sasse P.- Tuesday, March 24, Hall 3Oral SessionEndothelial cell biology: NO, NADPH oxidaseChairpersons: H. Morawietz (Dresden)U. Pohl (Mnchen) The 2-adrenoceptor antagonist ICI 118,551 relaxes pulmonary arteries via a Gi/o protein-dependent NO release
     - Cardiomyocytes within the vena cava are pacing the embryonic heart
    Satir P.- Monday, March 23, Hall 5Oral SessionCell migrationChairpersons: E. Schlatter (Mnster)H.-J. Schnittler (Dresden) The Na+/H+ exchanger NHE1 plays a central role in directional fibroblast migration stimulated via PDGFR signaling in the primary cilium
    Sauer F.- Possible atheroprotective effects of hyaluronic acid from the endothelial surface layer
    Sauer H.- NAD(P)H oxidases are key regulators of cardiomyocyte differentiation from embryonic stem cells
     - Characterisation of the 5-lipoxygenase pathway and leukotriene receptors in differentiating mouse embryonic stem cell derived embryoid bodies
     - Tumor-induced angiogenesis analyzed in confrontation cultures of multicellular tumor spheroids and embryonic stem cell-derived embryoid bodies
     - Signal transduction ofplatelet-derived growth factor BB action enhancing vasculogenesis of embryonic stem cells
     - Investigating the interplay of NO and ROS during cardiomyocyte differentiation from mouse embryonic stem cells
     - Nox1, Nox2 and Nox4 are key regulators of mouse embryonic stem cell-derived cardiovascular differentiation
     - Stimulation of cardiomyogenesis of embryonic stem cells by nitric oxide downstream of AMPK and mTOR signalling pathways
     - Phosphoinositide 3-kinases (PI3Ks) control early steps of cardiovascular differentiation of mouse embryonic stem cells
     - Metabolic pathways regulate P-glycoprotein gene expression via reactive oxygen species
    Sausbier M.- Control of aldosterone secretion by ANP in adrenal slices from mice with disrupted BK channel subunits
     - Adrenaline-induced colonic K+ secretion is conducted via KCa1.1 (BK) channel: implications of a regulated ZERO splice variant
    Sauvant C.- Acidosis modulates invasiveness of rat prostate cancer cells (AT1) via MAPK
     - Impact of the metabolic tumor microenvironment on activity and expression of the multidrug resistance-related protein 1 (MRP1)
     - COX-inhibition restores renal organic anion transport and positively influences renal outcome in a rat model of ischemic acute kidney injury
     - Acidosis-induced activation of ERK1/2 and p38 kinases in rat prostate cancer cells (AT1)
     - Inhibition of cyclooxygenases positively influences proximal tubular cell impairment in an in vitro model of renal ischemia and reperfusion.
    Sava B.- GABAergic networks in the developing cerebral cortex are activated by taurine
    Sawamura T.- Impaired vascular function in small resistance arteries of LOX-1 overexpressing mice on high-fat diet
    Schaarschmidt G.- Monday, March 23, Audimax, Poster Area FPoster Session: Potassium channelsModerators: R. Preisig-Mller (Marburg)J. R. Schwarz (Hamburg) Functional characterization of voltage-gated potassium channels in human neural progenitor cells
     - Functional and molecular analysis of glutamate receptors in human midbrain-derived neural precursor cells
    Schaefer L.- Biglycan: A negative regulator of cardiac elastin expression in diabetic hearts
    Schafer N.- Thrombin activates NOX1 involving Gi and Rac1 in pulmonary artery smooth muscle cells
     - Tuesday, March 24, Audimax, Poster Area GPoster Session: Vascular function and remodelingModerators: R. P. Brandes (Frankfurt a. M.)G. Siegel (Berlin) Diet-induced obesity increases plasma aldosterone and impairs endothelial function
    Schafer T.- Predictors of hypoventilation in obese patients with sleep-related breathing disorders
    Schafers M.- Myricetin-induced modulation of voltage activated calcium and potassium channel currents in sensory neurones of rat
    Schaible H.-G.- Gait abnormalities as an indicator for pain or structural joint damage in antigen-induced arthritis of the rat
     - Sensitization of afferent nerve fibers by TNF in normal rat knee can be prevented by etanercept, COX-inhibitors, and by inhibitors of the p38 kinase pathway
     - Transient anoxic depolarization is unable to condition the brainstem of adult rats for spreading depression (SD)
     - Modulatory function ofPI3K in mu-opioid inhibition of voltage-gated calcium channels in nociceptive neurons
    Schaper W.- Accelerated collateral vessel growth in CD73-/- mice after hindlimb ischemia revealed by in vivo 3D magnetic resonance angiography
    Scharbrodt W.- Sunday, March 22, Hall 5Oral SessionCalcium signaling and calcium storesChairpersons: Y. Abdallah (Giessen)H. Sauer (Giessen) Ca2+-induced necrosis in human astrocytes after cerebral hemorrhage
     - Tuesday, March 24, Audimax, Poster Area CPoster Session: Cardiovascular pathophysiologyModerators: B. F. Becker (Mnchen)H.-G. Zimmer (Leipzig) The role of cytosolic Ca2+-oscillations for inflammation in human cerebrovascular endothelial cells after subarachnoid hemorrhage
    Schatzmann E.- Monday, March 23, Audimax, Poster Area BPoster Session: Cell migrationModerators: P. Dieterich (Dresden)C. Stock (Mnster) Carbonic anhydrase activity affects cell migration
    Schenk L.- Cyclosporin A induced apoptosis in primary cultured inner medullary collecting duct cells correlates with increased TNF expression
    Schiegnitz E.- Matrix metalloproteinases as repressors of hypertrophy in ventricular cardiomyocytes of rats
    Schillers H.- Real-time monitoring of cell elasticity and cytoskeletal dynamics in living cells with atomic force microscopy
     - CFTR expression controls the paracellular permeability of bronchial epithelium
    Schirmeyer J.- A conserved splice variant of NaV1.8 voltage-gated sodium channel from human dorsal root ganglion neurons
    Schlafke M. E.- Predictors of hypoventilation in obese patients with sleep-related breathing disorders
    Schlatter E.- Atrial natriuretic peptide antagonizes the vasopressin mediated water permeability in inner medullary collecting duct cells via proteinkinase G
     - Regulation of human organic cation transporter 2 (hOCT2) by the new interacting partner lysosomal associated protein transmembrane 4 alpha (LAPTM4A)
     - Cyclosporin A induced apoptosis in primary cultured inner medullary collecting duct cells correlates with increased TNF expression
    Schlegel N.- Atrial natriuretic peptide stimulates microvascular endothelial permeability
    Schleicher E.- Regulation of erythrocyte survival by AMP-activated protein kinase
    Schlichthorl G.- Identification of a C-terminal region causing intracellular retention of TASK-3 channels
     - Mutation of the critical histidine residue in the T1 domain of Kv2.1 prevents the heteromeric assembly of Kv2.1/Kv6.x channels
    Schlie S.- ATP modulates Cl- permeability in ratGFSHR-17 granulosa cells, the in vitro model of granulosa cells inmaturing follicle
    Schloss M.- sEH-deficiency attenuates neointima formation in the femoral artery cuff model of hyperlipidemic mice
    Schluter K.-D.- Biglycan: A negative regulator of cardiac elastin expression in diabetic hearts
     - Comparable parcrine effects of human progenitor cells irrespectively of the donor's age
     - Enhanced paracrine effects of cardiac progenitor cells depending on the underlying cardiovascular disease of the donor
     - Stimulation of the calcium receptor: A new positive inotropic intervention of the post-ischemic heart
     - Monday, March 23, Audimax, Poster Area DPoster Session: Regulation and myocardial metabolism and functionModerators: T. Noll (Giessen)H.-G. Zimmer (Leipzig) PPAR activation limits the nonenzymatic effect of renin on cell lengths in adult ventricular cardiomyocytes
     - The effect of hyperglycaemia on the -adrenoceptor responsiveness in adult ventricular cardiomyocytes
     - From risk to heart failure in mice: Identification of UCP-2 and biglycan as potential risk factors in the left ventricle leading to severe heart failure
     - The arginine competition: eNOS deficiency and polyamine metabolism
     - Intermedin, a hypoxia-regulated cardiac gene, worsens post-ischemic recovery and increases the susceptibility to apoptosis
     - Induction of diabetes like hyperfiltration in heterozygous eNOS mice overexpressing TGF-b1 does not depend on changes in the mRNA expression of fibrotic markers
     - Monday, March 23, Audimax, Poster Area DPoster Session: Exercise under physiological andpathophysiological conditionsModerators: N. Maassen (Hannover)S. Rohrbach (Halle/Saale) The effect of exercise on cardiac physiology of hypertensive animals: Risk reduction or risk progression?
     - Physical exercise and hypertension: Risk or benefit?
    Schluter T.- Unusual role of Kv2 channels in rat posterior cerebral small arteries
     - Superoxide formation in human intrarenal arteries is mainly due to NADPH oxidase activity and contributes to endothelium-dependent vasodilation
     - Amiloride potently lowers arterial pressure in Cyp1a1ren-2 transgenic rats without significant effects on small artery function
     - Monday, March 23, Hall 3Oral SessionRenal transport IChairpersons: C. Wagner (Zrich, CH)R. Warth (Regensburg) Cyclosporine A-induced increases of renal and hepatic MDR1 expression do not depend on renal MRP2
    Schmelz M.- NGF induces long-term changes in axonal excitability of mechano-insensitive C-afferents in pig skin, in vivo
     - Effects of local lidocaine application on conductive properties of human C-fibers
    Schmid C.- Amiloride potently lowers arterial pressure in Cyp1a1ren-2 transgenic rats without significant effects on small artery function
    Schmid H.A.- Pasireotide (SOM230) a new somatostatin analogue for the treatment of acromegaly, cushings disease and neuroendocrine tumors
    Schmid S.- Kindlin-3 is essential for firm leukocyte adhesion during inflammation in vivo
    Schmidt A.- eNOS patterns in human erythrocytes are regulated by physical exercise
    Schmidt H.- Effects of diffusion on dendritic calcium signaling
     - Calretinin exhibits anomalous subdiffusion and activity-dependent binding in dendrites of cerebellar granule cells
     - Monday, March 23, Audimax, Poster Area FPoster Session: Potassium channelsModerators: R. Preisig-Mller (Marburg)J. R. Schwarz (Hamburg) Functional characterization of voltage-gated potassium channels in human neural progenitor cells
    Schmidt K.- KCNJ10 potassium channels in the mouse distal nephron
    Schmidt R.- Effects of local lidocaine application on conductive properties of human C-fibers
    Schmidt S.- The non-gastric H+/K+-ATPase ATP12A exerts an anti-apoptotic effect on butyrate-treated myelomonocytic HL60 cells
     - Regulation of CD45 expression and correlation with apoptosis in myelomonocytic HL60 cells
     - ICln-self interactions assessed by fluorescence resonance energy transfer (FRET)
    Schmidt V.- Ca2+-dependent K+-channels (IK1, SK3) mediate arteriolar dilation in a distinct stimulus-dependent fashion
    Schmidt-Salzmann C.- Wednesday, March 25, Hall 5Oral SessionExcitatory ionotropic receptorsChairpersons: J. Bischofberger (Freiburg)N. Klcker (Freiburg) Glutamate receptors in mature and newly generated young hippocampal granule cells
    Schnedler N.- Sat-1 transport mechanisms and regulation of mRNA expression by oxalate precursors
    Schneider B.- Acidosis modulates invasiveness of rat prostate cancer cells (AT1) via MAPK
     - Acidosis-induced activation of ERK1/2 and p38 kinases in rat prostate cancer cells (AT1)
    Schneider L.- Monday, March 23, Hall 5Oral SessionCell migrationChairpersons: E. Schlatter (Mnster)H.-J. Schnittler (Dresden) The Na+/H+ exchanger NHE1 plays a central role in directional fibroblast migration stimulated via PDGFR signaling in the primary cilium
    Schneider M.- Loss of mitochondrial thioredoxin reductase (TrxR-2) limits tumor growth
    Schneider R.- COX-inhibition restores renal organic anion transport and positively influences renal outcome in a rat model of ischemic acute kidney injury
     - Inhibition of cyclooxygenases positively influences proximal tubular cell impairment in an in vitro model of renal ischemia and reperfusion.
    Schneider T.- Recombinant and native Cav2.3 E-type voltage-gated Ca2+ channels interact with the molecular chaperone Hsp70
    Schnell C.- Activity-dependent currents recorded from astrocytes in the respiratory network
    Schnelle M.- Impact of prolyl-4-hydroxylase domain (PHD) enzyme 2 on cell motility and adhesion
    Schnittler H.-J.- Tuesday, March 24, Hall 5Oral SessionMethods and teachingChairpersons: M. Diener (Giessen)P. B. Persson (Berlin) Detection and tracking of cells in confluent cell cultures within the framework of statistical pattern recognition
     - Shear stress induced endothelial cell-alignment depends on the production of reactive oxygen species
    Schnizler M.K.- The Acid-Sensing Ion Channel 1a confers pH-dependent Modulation of Excitability in Central Neurons
    Scholle H.-C.- Facial muscle activation patterns in healthy men - a multi-channel surface EMG study
     - Muscle activation patterns of selected ankle muscles in haemophilic patients during bipedal upright standing depending on Orthopaedic Joint Score
     - In vivo intramuscular electrical stimulation of rat triceps brachii with a multichannel electrode array
     - The back muscles of laboratory rats
    Scholz H.- Tuesday, March 24, Audimax, Poster Area EPoster Session: Neural degeneration and agingModerators: D. Bsselberg (El Paso, US),M. Diener (Giessen) Fragile X mental retardation protein (FMRP) stimulates translation of the human achaete-scute homologue-1 (hASH1) mRNA
     - The Wilms tumor suppressor WT1 regulates interleukin-10 expression in macrophagocytic cells
     - Is the TrkB neurotrophin receptor transcriptionally activated during pulmonary inflammation?
    Scholz T.- A novel role of class 1 myosin: The tail domain of a class 1 myosin binds and stabilizes microtubules and modulates kinesin motility
    Schon P.- Endothelial cell stiffness explored by a combination of fluorescence and atomic force microscopy
    Schonfeld P.- Possible explanation of the contrasting effects of minocycline in experiments on mitochondria and in a clinical study
    Schonherr R.- Thiol-dependent modulation of human EAG1 potassium channels
     - Tuesday, March 24, Hall 4Oral SessionPotassium channelsChairpersons: R. Bhring (Hamburg)S. H. Heinemann (Jena) EAG genes in Danio rerio coding for functional potassium channels
    Schrader J.- Accelerated atherosclerosis inapolipoprotein E/ecto-5nucleotidase (CD73) double-deficient mice
     - Sunday, March 22, Hall 3Oral SessionRespiratory inflammation and gas exchangeChairpersons: G. Gros (Hannover)W. Kuebler (Berlin) Early detection of pneumonia by 19F magnetic resonance imaging
     - Comparative phosphoproteome analysis of NO induced heart failure
     - Role of CD73 (ecto-5-nucleotidase) on T-cell mediated immune response
     - Impaired cardiac function in old but not in young mice after IGF1-receptor knockout
     - Accelerated collateral vessel growth in CD73-/- mice after hindlimb ischemia revealed by in vivo 3D magnetic resonance angiography
    Schrader M.- Novel antiangiogenic compounds for innovative treatment of renal cell carcinoma
    Schraml P.- Onconeuronal cerebellar degeneration-related antigen Cdr2 is strongly expressed in papillary renal cell carcinoma and leads to attenuated hypoxic response
    Schreckenberg R.- From risk to heart failure in mice: Identification of UCP-2 and biglycan as potential risk factors in the left ventricle leading to severe heart failure
     - The arginine competition: eNOS deficiency and polyamine metabolism
     - Monday, March 23, Audimax, Poster Area DPoster Session: Regulation and myocardial metabolism and functionModerators: T. Noll (Giessen)H.-G. Zimmer (Leipzig) PPAR activation limits the nonenzymatic effect of renin on cell lengths in adult ventricular cardiomyocytes
     - Intermedin, a hypoxia-regulated cardiac gene, worsens post-ischemic recovery and increases the susceptibility to apoptosis
     - Stimulation of the calcium receptor: A new positive inotropic intervention of the post-ischemic heart
     - Biglycan: A negative regulator of cardiac elastin expression in diabetic hearts
     - Comparable parcrine effects of human progenitor cells irrespectively of the donor's age
     - Induction of diabetes like hyperfiltration in heterozygous eNOS mice overexpressing TGF-b1 does not depend on changes in the mRNA expression of fibrotic markers
     - Monday, March 23, Audimax, Poster Area DPoster Session: Exercise under physiological andpathophysiological conditionsModerators: N. Maassen (Hannover)S. Rohrbach (Halle/Saale) The effect of exercise on cardiac physiology of hypertensive animals: Risk reduction or risk progression?
     - Physical exercise and hypertension: Risk or benefit?
    Schreiber A.- Kidney-specific deficiency of PPAR results in increased mouse renin production
    Schreiber D.- Comparison of the affinities of PI(4,5)P2-binding domains in living cells with the help of the voltage-controlled PI(4,5)P2-5-phosphatase Ci-VSP
    Schreiber R.- Tuesday, March 24, Audimax, Poster Area FPoster Session: LungModerators: K. Kunzelmann (Regensburg)H. Schillers (Mnster) ER localized and Pak2 phosphorylated bestrophin 1 confers receptor activation of epithelial Ca2+ dependet ion channels
     - Regulatory volume decrease by the calcium activated chloride channel TMEM16A
     - Control of ion transport by AMPK: Is it important?
     - Monday, March 23, Hall 3Oral SessionEpitheliumChairpersons: K. Kunzelmann (Regensburg)H. Oberleithner (Mnster) Defective Ca2+ dependent chloride secretion by TMEM16A knockdown
     - Annexin V binds to CFTR and regulates its endocytosis
    Schreier B.- Direct interaction of mineralocorticoid receptor and EGF receptor
    Schroder J.- Renal pathophysiology in mice deficient for the tetraspaninCD63/LIMP-1
    Schroder K.- Hypoxia-induced vascular repair by progenitor cells requires the NADPH oxidase Nox2
     - Monday, March 23, Audimax, Poster Area FPoster Session: NO- and extracellular nucleotidesModerators: U. Decking (Dsseldorf)A. Deussen (Dresden) Nox4 controls the phosphatase MKP-1
    Schroder U.- Inhibition of Na+/H+ exchangers protects hippocampal slices from oxygen-glucose-deprivation induced injury
    Schroeder B.- Effect of 1,25-dihydroxyvitamin D3 on macromineral homoeostasis of sheep fed different levels of calcium
     - Dietary N supply modulates jejunal glucose absorption in goats
    Schroeder K.- Downregulation of Na+/H+ exchanger isoform 3 (NHE3) function, but not expression, in colonic mucosa of patients with ulcerative colitis may be related to loss of PDZK1 adaptor protein expression
    Schroter J.- Posttranslational modifications of the GC-A receptor for atrial natriuretic peptide: Characterization by mass spectrometry application
     - Regulation of guanylyl cyclase-A, the receptor for atrial natriuretic peptide, by alternative splicing
    Schubert R.- Unusual role of Kv2 channels in rat posterior cerebral small arteries
     - Doxycycline treatment attenuates the development of aortic lesions in the mouse experimental model of vascular type of the Ehlers-Danlos syndrome
    Schubring S. R.- Bile salts block GABAA receptors and GABAergic transmission
    Schuh K.- ATIP-1 gene trapping provides first evidence for an important physiological function of ATIP-1 in the heart
     - Dysregulation of hypothalamic-pituitary-adrenal hormone secretion in SPRED2-deficient mice
     - Novel Cav1.2 and PMCA4b interacting PDZ domain containing proteins
    Schuier M.- Suicidal erythrocyte death associated with cholestasis
    Schuler C.- Functional interaction of carbonic anhydrase isoforms I, II and III with the electrogenic sodium-bicarbonate cotransporter NBCe1
    Schulte U.- Association with the auxiliary subunit PEX5R/Trip8b controls responsiveness of HCN channels to cAMP
     - A novel family of proteins that control trafficking and gating of AMPA receptors
    Schultze A.- Possible explanation of the contrasting effects of minocycline in experiments on mitochondria and in a clinical study
    Schulz E.- Relating ligand binding to gating in HCN2 channels
     - Heterotetrameric olfactory CNG channels are activated by the ligand binding to the two CNGA2 subunits only
     - Regulation of erythrocyte survival by AMP-activated protein kinase
    Schulzke J. D.- Tuesday, March 24, Hall 4Oral SessionKidney PhysiologyChairpersons: M. Gekle (Halle/Saale),F. Schweda (Regensburg) Tricellulin enhances the barrier for ions and for macromolecules depending on its localization within the tight junction
     - Functional and molecular analyses of absorption enhancers in an epithelial cell model
    Schumann N. P.- The back muscles of laboratory rats
     - In vivo intramuscular electrical stimulation of rat triceps brachii with a multichannel electrode array
     - Facial muscle activation patterns in healthy men - a multi-channel surface EMG study
    Schunck W.-H.- Novel interaction between P450 eicosanoidsandendothelial nitric oxide in thecontrol arterial tone in mice
    Schwab A.- pH-regulatory ion transport in MCF-7 breast cancer cells: Effects of truncated ErbB2 receptor expression on transporter expression and activity, and role in resistance to cisplatin-induced death
     - The role of the Ca2+ channels TRPC1 and TRPC6 in neutrophil migration
     - The molecular compass for macrophage chemotaxis
     - Monday, March 23, Hall 4Oral SessionTRP channelsChairpersons: A. Cavali (Homburg/Saar)A. Schwab (Mnster) TRPC1 channels guide migrating cells in chemokine gradients
     - Monday, March 23, Hall 5Oral SessionCell migrationChairpersons: E. Schlatter (Mnster)H.-J. Schnittler (Dresden) The Na+/H+ exchanger NHE1 plays a central role in directional fibroblast migration stimulated via PDGFR signaling in the primary cilium
     - A N-terminally truncated ErbB2 receptor enhances migration of MCF-7 breast cancer cells: Roles of the Na+/H+ exchanger NHE1 and of cytoskeletal reorganization
     - NHE1-activity creates an intracellular pH-gradient in human melanoma cells
     - Monday, March 23, Audimax, Poster Area BPoster Session: Cell migrationModerators: P. Dieterich (Dresden)C. Stock (Mnster) Carbonic anhydrase activity affects cell migration
     - Effects of modified 1-integrin expression on pH-dependent adhesion and migration of human melanoma cells
     - Analysis and quantification of cell migration during chemotaxis
     - Extracellular matrix digestion depends on the matrix composition and on NHE1 activity
     - Single-cell caspase-3/7 imaging: P2X7 receptor activation triggers cell death
    Schwaller B.- Calretinin exhibits anomalous subdiffusion and activity-dependent binding in dendrites of cerebellar granule cells
    Schwarz J.- Monday, March 23, Audimax, Poster Area FPoster Session: Potassium channelsModerators: R. Preisig-Mller (Marburg)J. R. Schwarz (Hamburg) Functional characterization of voltage-gated potassium channels in human neural progenitor cells
     - Functional and molecular analysis of glutamate receptors in human midbrain-derived neural precursor cells
    Schwarz J. R.- Erg K+ currents in gonadotropes
    Schwarz K.- Atrial (ANP) and B-type natriuretic peptides (BNP) stimulate endothelial matrix metalloproteinase secretion and postischemic endothelial regeneration
    Schwarz S. C.- Functional and molecular analysis of glutamate receptors in human midbrain-derived neural precursor cells
    Schweda F.- Gap junctions and renal control of blood pressure
     - Kidney-specific deficiency of PPAR results in increased mouse renin production
     - Monday, March 23, Hall 1Main SessionPhysiology and pathophysiology of K2P -channelsSymposium of the Working Group Heart and Circulation PhysiologyChairpersons: J. Daut (Marburg)R. Warth (Regensburg) Invalidation of TASK1 K+ channels disrupts adrenal gland zonation and mineralocorticoid homeostasis
    Schwede F.- Heterotetrameric olfactory CNG channels are activated by the ligand binding to the two CNGA2 subunits only
     - Relating ligand binding to gating in HCN2 channels
    Schweinfest C. W.- Genetic deletion of NHE3, Slc26a6 (PAT1), Slc26a3 (DRA) and CFTR helps unravel the different pathways for duodenal HCO3- and H+ secretion in vivo
    Schwenk J.- A novel family of proteins that control trafficking and gating of AMPA receptors
    Schwerdt G.- The influence of aldosterone and NaCl on vascular smooth muscle cells
    Schymeinsky J.- Monday, March 23, Hall 4Oral SessionVascular inflammation: Basic aspectsChairpersons: H.-J. Schnittler (Dresden)B. Walzog (Mnchen) The mammalian actin binding protein 1 (mAbp1) is required for firm arrest and intraluminal crawling of neutrophils during the acute inflammatory response
    Sciesielski L.- Is the TrkB neurotrophin receptor transcriptionally activated during pulmonary inflammation?
    Sedding D.- Role of extracellular RNA on vascular permeability, edema formation and myocardial infarction size
     - Role of Sirt1 in vascular homeostasis and pathologic remodeling
     - The regulator of G protein signaling 5 (RGS5) prevents cell cycle entry and proliferation of smooth muscle cells and attenuates neointima formation
     - Time course analysis of bone marrow derived progenitor cell transdifferentiation during neointima formation
     - miRNA-dependent regulation of smooth muscle cell function during neointima formation
    Seebach J.- Shear stress induced endothelial cell-alignment depends on the production of reactive oxygen species
    Seebohm B.- Hypertrophic cardiomyopathy mutations R723G and R453C in the myosin head homain cause force enhancement by different mechanisms
    Seebohm G.- Altered stress-dependent IKs channel trafficking in LQTS
     - Regulation of the EAAT3 by PIKfyve
     - Long QT syndrome-associated mutations in the voltage sensor of IKs channels may favor early after depolarizations
     - PIP5k2A-dependent regulation of the excitatory amino acid transporter EAAT3
     - Disruption of stimulation of glutamate receptors by a schizophrenia-associated kinase mutant
    Seeger T.- Hypoxia prolonged effects of the central cholinergic modulation of breathing after organophosphorus poisoning in the perfused brainstem preparation of rat
    Seeger W.- Carbon monoxide rapidly impairs alveolar fluid clearance by inhibiting epithelial sodium channels
     - The cytoskeletal protein paxillin is associated with pulmonary vascular remodeling
     - Carbon monoxide modulates the activity of sodium channels in the alveolar epithelium: A role for ENaC?
    Seemann W.- Effect of a new type of muscarinic acetylcholine receptor activator on sarcomere shortening in isolated murine cardiac myocytes
    Segond von Banchet G.- Modulatory function ofPI3K in mu-opioid inhibition of voltage-gated calcium channels in nociceptive neurons
    Seidel T.- Is there any evidence for ephaptic coupling? A computer simulation study giving new insights
    Seidler U.- Effect of genetic ablation of the acid/base transporters pNBC1, NHE1, NHE2, and Slc26a7, on gastric epithelial functions
     - Preserved abundance but functional dysregulation of Na+/H+ exchanger isoform NHE3 in the small and large intestine in CD45RBhigh transfer colitis mice with diarrhea
     - Downregulation of Na+/H+ exchanger isoform 3 (NHE3) function, but not expression, in colonic mucosa of patients with ulcerative colitis may be related to loss of PDZK1 adaptor protein expression
     - Secretagogue stimulation enhances NBCe1-B (electrogenic intestinal/pancreatic Na+/HCO3- cotransporter) surface expression in murine colonic crypts
     - NBCn1 (Slc4a7) is a major HCO3- importer in murine duodenum and essential for basal and stimulated HCO3- secretion in vivo
     - Monday, March 23, Audimax, Poster Area EPoster Session: Gut and epithelial transporters IModerators: M. Ritter (Salzburg, AT)J. Roth (Giessen) Dual role of the Na+/H+ exchanger isoform 3 for PEPT1-mediated H+/dipeptide cotransport in native murine intestine
     - Sunday, March 22, Audimax, Poster Area BPoster SessionYoung Investigator Award (Poster):Channels and transportModerators: J. Daut (Marburg)J. Leipziger (Aarhus, DK) The PDZ proteins NHERF1 and NHERF2 have distinct roles in G-protein coupled receptor regulation of CFTR-mediated intestinal anion secretion in vivo
     - Genetic deletion of NHE3, Slc26a6 (PAT1), Slc26a3 (DRA) and CFTR helps unravel the different pathways for duodenal HCO3- and H+ secretion in vivo
     - Sunday, March 22, Hall 4Oral SessionIntestinal transportChairpersons: M. Bleich (Kiel)G. Breves (Hannover) Gastric KNCQ1 channels provide luminal K+ to the H+/K+ ATPase, whereas Kir 4.1 channels are involved in secretory membrane recycling
     - Adrenaline-induced colonic K+ secretion is conducted via KCa1.1 (BK) channel: implications of a regulated ZERO splice variant
    Seja P.- The two-pore domain channel TRESK is the major component of potassium background current and a molecular target for plant ingredients in DRG neurons
    Selbach O.- Excitation of histaminergic tuberomamillary neurons by thyrotropin-releasing hormone
    Semke A.- PIP5k2A-dependent regulation of the excitatory amino acid transporter EAAT3
    Sergeeva O. A.- Excitation of histaminergic tuberomamillary neurons by thyrotropin-releasing hormone
     - Bile salts block GABAA receptors and GABAergic transmission
    Seringer J.- Novel interaction between P450 eicosanoidsandendothelial nitric oxide in thecontrol arterial tone in mice
    Shah M.- Involvement of PI3K/AKT pathway in the hypoglycemic effects of saponins from Helicteres isora
    Shahin V.- Caspases 3 and 9 pave the way for apoptosis through breakdown of the nuclear barrier
     - Delivery of herpes simplex virus type 1 genome through the nuclear pore complex
    Shahzad T.- The role of cellular pH and mitochondrial permeability transition pore (MPTP) in postconditioning-mediated protection against acute myocardial reperfusion injury
     - Wednesday, 25 March, Hall 3Oral SessionSarcomeric and mitochondrial function in cardiac andskeletal muscleChairpersons: K. Boengler (Essen)T. Kraft (Hannover) Protection of cardiac myocytes against reperfusion injury through inhibition of glycogen synthase kinase-3 (GSK-3) involves the mitochondrial permeability transition pore (MPTP)
     - ANT1-overexpression compensates TGF induced apoptosis via stabilization of the mitochondrial permeability transition pore
    Shan Q.- Extracellular Ca2+ regulates paracellular permeability in the thick ascending limb of mouse kidney
    Shcherbyna I.- Sodium dependence of glutamate transport by a prokaryotic glutamate transporter
     - Cation binding by bacterial glutamate transporters characterized through equilibrium and stop flow tryptophane fluorescence
    Shull G.- Effect of genetic ablation of the acid/base transporters pNBC1, NHE1, NHE2, and Slc26a7, on gastric epithelial functions
     - Secretagogue stimulation enhances NBCe1-B (electrogenic intestinal/pancreatic Na+/HCO3- cotransporter) surface expression in murine colonic crypts
     - Monday, March 23, Audimax, Poster Area EPoster Session: Gut and epithelial transporters IModerators: M. Ritter (Salzburg, AT)J. Roth (Giessen) Dual role of the Na+/H+ exchanger isoform 3 for PEPT1-mediated H+/dipeptide cotransport in native murine intestine
    Shumilina E.- Effects of glucocorticoids on regulation of cytosolic Ca2+ activityin dendritic cells
     - Involvement of phosphoinositide dependent kinase PDK1 in the regulation of channel activity in pancreatic beta cells by epinephrine
     - Blunted activation of mast cells in mice lacking the serum- and glucocorticoid-inducible kinase SGK3
     - Ca2+-dependent functions in peptidoglycan-stimulated mouse dendritic cells
     - Regulation of calcium signaling in dendritic cells by 1,25-dihydroxyvitamin D3
    Sickmann A.- Posttranslational modifications of the GC-A receptor for atrial natriuretic peptide: Characterization by mass spectrometry application
    Siegel G.- Arteriosclerosis prophylaxis by Ginkgo biloba (EGb 761) in patients with metabolic syndrome
     - Possible atheroprotective effects of hyaluronic acid from the endothelial surface layer
    Siegl T.- Monday, March 23, Audimax, Poster Area APoster Session: EpilepsyModerators: A. Draguhn (Heidelberg)S. Hefft (Freiburg) Effects of levetiracetam on principal cells and interneurons in hippocampal slices
    Siemen D.- Possible explanation of the contrasting effects of minocycline in experiments on mitochondria and in a clinical study
    Sigrist S. J.- Bruchpilot filaments accelerate vesicle reloading at active zones
     - The LEM-domain protein MAN1 is required for presynaptic function at the drosophila neuromuscular junction
    Silber R.-E.- AMPK activation is indispensable for the protective effects of caloric restriction on left ventricular function in the postinfarct myocardium
     - Long-term caloric restriction improves mitochondrial and left ventricular function in senescent rats
    Silter M.- Hypoxia-inducible factor-1 affects cardiac function during chronic pressure overload
    Silva A.- Pasireotide (SOM230) a new somatostatin analogue for the treatment of acromegaly, cushings disease and neuroendocrine tumors
    Silver S.- A new 2-photon imaging method for studying neural activity in 3D
    Simon A.- Identification of protein interactions of AKT2 via TAP and MS
     - Comparative phosphoproteome analysis of NO induced heart failure
    Sindic A.- Atrial natriuretic peptide antagonizes the vasopressin mediated water permeability in inner medullary collecting duct cells via proteinkinase G
    Singer D.- ACE2 and collectrin are tissue-specific associated proteins of the amino acid transporter B0AT1 and B0AT1-Hartnup-causing mutations
    Singh A. K.- Monday, March 23, Audimax, Poster Area EPoster Session: Gut and epithelial transporters IModerators: M. Ritter (Salzburg, AT)J. Roth (Giessen) Dual role of the Na+/H+ exchanger isoform 3 for PEPT1-mediated H+/dipeptide cotransport in native murine intestine
     - Preserved abundance but functional dysregulation of Na+/H+ exchanger isoform NHE3 in the small and large intestine in CD45RBhigh transfer colitis mice with diarrhea
    Singh A.K.- Genetic deletion of NHE3, Slc26a6 (PAT1), Slc26a3 (DRA) and CFTR helps unravel the different pathways for duodenal HCO3- and H+ secretion in vivo
     - Sunday, March 22, Audimax, Poster Area BPoster SessionYoung Investigator Award (Poster):Channels and transportModerators: J. Daut (Marburg)J. Leipziger (Aarhus, DK) The PDZ proteins NHERF1 and NHERF2 have distinct roles in G-protein coupled receptor regulation of CFTR-mediated intestinal anion secretion in vivo
    Siraskar B.- Monday, March 23, Audimax, Poster Area CPoster Session: Kidney IModerators: W. Neuhofer (Mnchen)W. H. Castrop (Regensburg) Renal function of PDK1 hypomorphic mice
     - Responses to diuretic treatment of SGK1 knockout mice
    Skals M.- Hemolysis induced bya-hemolysin from Escherichia coli requires P2X and pannexin receptor activation
    Skalweit A.- Untranslated regionsof the ENaC subunit mRNA act as targets forregulatory binding proteins in kidney cell lines
    Skovby F.- ACE2 and collectrin are tissue-specific associated proteins of the amino acid transporter B0AT1 and B0AT1-Hartnup-causing mutations
    Skrobek L.- Mutation of the critical histidine residue in the T1 domain of Kv2.1 prevents the heteromeric assembly of Kv2.1/Kv6.x channels
    Smith C. P.- Role of ferroportin-1 (FPN-1) in renal iron (Fe) handling
    Smolka A.- Sunday, March 22, Hall 4Oral SessionIntestinal transportChairpersons: M. Bleich (Kiel)G. Breves (Hannover) Gastric KNCQ1 channels provide luminal K+ to the H+/K+ ATPase, whereas Kir 4.1 channels are involved in secretory membrane recycling
    Sobczak K.- Establishing mRNA transfection procedures for functional CFTR correction
     - Characterization of the epithelial sodium channel delta subunit in human nasal epithelium
    Soleimani M.- Genetic deletion of NHE3, Slc26a6 (PAT1), Slc26a3 (DRA) and CFTR helps unravel the different pathways for duodenal HCO3- and H+ secretion in vivo
     - Monday, March 23, Audimax, Poster Area EPoster Session: Gut and epithelial transporters IModerators: M. Ritter (Salzburg, AT)J. Roth (Giessen) Dual role of the Na+/H+ exchanger isoform 3 for PEPT1-mediated H+/dipeptide cotransport in native murine intestine
     - Effect of genetic ablation of the acid/base transporters pNBC1, NHE1, NHE2, and Slc26a7, on gastric epithelial functions
    Solzin J.- Is contraction or relaxation of rabbit psoas myofibrils rate-limited by Ca2+-regulated switch of the troponin complex?
     - The impact of the FHC-associated mutation K183 of troponin I on the Ca2+-transients of cardiomyocytes
    Somlyo A.- Endothelium dependent modulation of phosphorylation of smooth muscle myosin phosphatase in brain vessels by the thromboxane A2 mimetic, U-46619
    Song P.- Effect of genetic ablation of the acid/base transporters pNBC1, NHE1, NHE2, and Slc26a7, on gastric epithelial functions
     - Sunday, March 22, Hall 4Oral SessionIntestinal transportChairpersons: M. Bleich (Kiel)G. Breves (Hannover) Gastric KNCQ1 channels provide luminal K+ to the H+/K+ ATPase, whereas Kir 4.1 channels are involved in secretory membrane recycling
    Sontheimer H. W.- Monday, March 23, Hall 4Oral SessionTRP channelsChairpersons: A. Cavali (Homburg/Saar)A. Schwab (Mnster) TRPC1 channels guide migrating cells in chemokine gradients
    Soom M.- Functional impact of the S6-RCK linker in BK channels
    Sopjani M.- Regulation of erythrocyte survival by AMP-activated protein kinase
     - Stimulation of the Na+-glucose cotransporter SGLT1 by AMP-activated protein kinase
    Sorensen M.V.- Impaired aldosterone responsiveness in corticosteroid binding gobulin deficient mice
     - Adrenaline-induced colonic K+ secretion is conducted via KCa1.1 (BK) channel: implications of a regulated ZERO splice variant
    Speckmann E.-J.- Spreading depression triggers epileptiform activity in combined amygdala-hippocampus-neocortex tissues
     - The effect of DC potential shifts associated with quenching thirst on neuronal network activities
    Sperandio M.- Monday, March 23, Hall 4Oral SessionVascular inflammation: Basic aspectsChairpersons: H.-J. Schnittler (Dresden)B. Walzog (Mnchen) The mammalian actin binding protein 1 (mAbp1) is required for firm arrest and intraluminal crawling of neutrophils during the acute inflammatory response
     - Kindlin-3 is essential for firm leukocyte adhesion during inflammation in vivo
    Sperlich B.- Effects of active or passive recovery between high-intensity cycling bouts on power output, lactate and pH time course
     - Physiological differences between three step test designs in front crawl swimming
    Springauf A.- Characterization of sharkASIC1b, an ancient form of an acid-sensing ion channel
    Stange G.- Tuesday, March 24, Audimax, Poster Area CPoster Session: Gut and epithelial transporters IIModerators: S. Amasheh (Berlin)U. Seidler (Hannover) Expression and dietary modulation of intestinal phosphate cotransporters
     - Differential regulation of three renal phosphate transporters by parathyroid hormone (PTH)
    Stanojlovic O.- Pretreatment with L-arginine reverse redutionof brain Na+/K+ ATPase activity induced by homocysteine thiolactone in adult rats
     - L-NAME potentiate homocysteine-induced convulsions in adult rats
    Steege A.- Impact of M3 and M5 acetylcholine receptors on cholinergic dilatation of mesenteric arteries in genetically modified mice
     - EazyClone: A user-friendly application for the development of cloning strategies
     - Seed based systematic discovery of specific transcription factor target genes
     - Tuesday, March 24, Audimax, Poster Area EPoster Session: Neural degeneration and agingModerators: D. Bsselberg (El Paso, US),M. Diener (Giessen) Fragile X mental retardation protein (FMRP) stimulates translation of the human achaete-scute homologue-1 (hASH1) mRNA
    Stehle R.- Is contraction or relaxation of rabbit psoas myofibrils rate-limited by Ca2+-regulated switch of the troponin complex?
     - The impact of the FHC-associated mutation K183 of troponin I on the Ca2+-transients of cardiomyocytes
    Steidle J.- Carbon monoxide-induced anion secretion across rat distal colon
    Steimel M.- Metabolic adaptation of tumor-initiating cells is a key factor determining angiogenesis in a sarcoma allograft model
    Steinbach A.- Monday, March 23, Hall 3Oral SessionRenal transport IChairpersons: C. Wagner (Zrich, CH)R. Warth (Regensburg) Cyclosporine A-induced increases of renal and hepatic MDR1 expression do not depend on renal MRP2
    Steinbeck G.- Genetic or pharmacological CD26/DPP-IV inhibition combined with G-CSF administration enhances homing of stem cells and improves ventricular function after acute myocardial infarction
    Steinberg T. H.- Sphingosine-1-phosphate receptors stimulate macrophage plasma membrane actin assembly via ADP release, ATP synthesis and P2X7 receptor activation
    Steinbrenner D.- Simultaneous capacitance and fluorescence detection of single vesicle exocytosis
    Steinert D.- EGF receptor signaling is involved in expression of osmoprotective TonEBP target gene aldose reductase under hypertonic conditions
     - COX-2-derived cyclopentenone prostaglandins stimulate the expression of the sHSP B-Crystallin in renal medullary cells during osmotic stress
    Steinke K.- Disruption of stimulation of glutamate receptors by a schizophrenia-associated kinase mutant
     - Altered stress-dependent IKs channel trafficking in LQTS
    Stengel R.- Tuesday, March 24, Hall 4Oral SessionPotassium channelsChairpersons: R. Bhring (Hamburg)S. H. Heinemann (Jena) EAG genes in Danio rerio coding for functional potassium channels
    Stepulak A.- Electrophysiological properties of AMPA receptor mediated currents in tumor cells
    Sternberg D.- A myotonia-causing mutation in the selectivity filter of human ClC-1 channels affects slow gating
    Sterner C.- Monday, March 23, Audimax, Poster Area BPoster Session: Neuroprotection and hypoxiaModerators: D. Katschinski (Gttingen)U. Schrder (Magdeburg) TASK2 potassium channels are important determinants for central respiratory adaptation to hypoxia
     - KCNJ10 potassium channels in the mouse distal nephron
     - Expression and localization of the TASK K+ channels in adrenal glands
     - The role of TASK3 potassium channel in the regulation of aldosterone secretion
     - Monday, March 23, Hall 1Main SessionPhysiology and pathophysiology of K2P -channelsSymposium of the Working Group Heart and Circulation PhysiologyChairpersons: J. Daut (Marburg)R. Warth (Regensburg) Invalidation of TASK1 K+ channels disrupts adrenal gland zonation and mineralocorticoid homeostasis
    Stieger N.- NBCn1 (Slc4a7) is a major HCO3- importer in murine duodenum and essential for basal and stimulated HCO3- secretion in vivo
    Stieger P.- Role of extracellular RNA on vascular permeability, edema formation and myocardial infarction size
     - miRNA-dependent regulation of smooth muscle cell function during neointima formation
     - The regulator of G protein signaling 5 (RGS5) prevents cell cycle entry and proliferation of smooth muscle cells and attenuates neointima formation
    Stiehl D. S.- Onconeuronal cerebellar degeneration-related antigen Cdr2 is strongly expressed in papillary renal cell carcinoma and leads to attenuated hypoxic response
    Stock C.- NHE1-activity creates an intracellular pH-gradient in human melanoma cells
     - Effects of modified 1-integrin expression on pH-dependent adhesion and migration of human melanoma cells
     - Monday, March 23, Audimax, Poster Area BPoster Session: Cell migrationModerators: P. Dieterich (Dresden)C. Stock (Mnster) Carbonic anhydrase activity affects cell migration
     - Extracellular matrix digestion depends on the matrix composition and on NHE1 activity
     - A N-terminally truncated ErbB2 receptor enhances migration of MCF-7 breast cancer cells: Roles of the Na+/H+ exchanger NHE1 and of cytoskeletal reorganization
     - Monday, March 23, Hall 5Oral SessionCell migrationChairpersons: E. Schlatter (Mnster)H.-J. Schnittler (Dresden) The Na+/H+ exchanger NHE1 plays a central role in directional fibroblast migration stimulated via PDGFR signaling in the primary cilium
     - pH-regulatory ion transport in MCF-7 breast cancer cells: Effects of truncated ErbB2 receptor expression on transporter expression and activity, and role in resistance to cisplatin-induced death
     - Endothelial cell stiffness explored by a combination of fluorescence and atomic force microscopy
    Stocker M.- Towards a better understanding of SK channel physiology and pharmacology
    Stolle V.- Tuesday, March 24, Hall 3Oral SessionEndothelial cell biology: NO, NADPH oxidaseChairpersons: H. Morawietz (Dresden)U. Pohl (Mnchen) The 2-adrenoceptor antagonist ICI 118,551 relaxes pulmonary arteries via a Gi/o protein-dependent NO release
    Stolze I.- Monday, 23 March, Audimax, Poster Area CPoster Session: Angiogenesis and hypoxiaModerators: T. Gloe (Mannheim)H. Sauer (Giessen) Retinoic acid enhance the erythropoietin genexpression under hypoxia in neuroblastoma cells
    Storch U.- TRPC1 suppresses the Ca2+ permeability in heteromeric channel complexes without effects on arterial tone
    Stournaras C.- SGK1-dependent downregulation of Foxo3a promotes growth of colon tumors
     - Colon tumors express functional membrane androgen receptors that trigger pro-apoptotic responses
    Straeter A.S.- Epithelial Na+ channels of endothelial are regulated by aldosterone
    Strassburger M.- Inhibition of Na+/H+ exchangers protects hippocampal slices from oxygen-glucose-deprivation induced injury
    Strauss O.- Systemic activation of the renin-angiotensin system causes stimulation of the intraocular renin-angiotensin system
     - Role of Ca2+-channels in the regulation of phagocytosis by retinal pigment epithelium
     - Mice have light-induced retinal damage at low light intensity
    Strehlow F.- Tuesday, March 24, Audimax, Poster Area EPoster Session: Transporters and channelsModerators: K. Benndorf (Jena)S. Grnder (Aachen) The increase in AMPA receptor surface expression by auxAMPARs critically depends on receptor conformation
     - AuxAMPARs promote surface expression of AMPA receptors by selective ER export
    Strutz-Seebohm N.- Regulation of the EAAT3 by PIKfyve
     - Altered stress-dependent IKs channel trafficking in LQTS
     - Disruption of stimulation of glutamate receptors by a schizophrenia-associated kinase mutant
     - PIP5k2A-dependent regulation of the excitatory amino acid transporter EAAT3
     - Long QT syndrome-associated mutations in the voltage sensor of IKs channels may favor early after depolarizations
    Stumpff F.- Ruminal epithelial cells express a conductance for propionate
    Suhr F.- Extracellular matrix proteins are regulated by exhaustive exercise in trained athletes
     - eNOS patterns in human erythrocytes are regulated by physical exercise
    Suresh S.- Wall tension-induced signaling in endothelial cells
    Surmeier J.- Tuesday, March 24, Hall 1Main SessionSources and sensors - calcium signaling at theplasma membraneSymposium of the Working Group Voltage-operated Ion ChannelsChairpersons: J. Roeper (Frankfurt a. M.)H. Terlau (Lbeck) Is the reliance upon calcium the key to selective neuronal vulnerability in Parkinsons disease?
    Susic V.- Pretreatment with L-arginine reverse redutionof brain Na+/K+ ATPase activity induced by homocysteine thiolactone in adult rats
     - L-NAME potentiate homocysteine-induced convulsions in adult rats
    Swandulla D.- Modulation of the Ca2+ conductance of nicotinic acetylcholine receptors by the endogenous protein Lypd6
    Szafranski K.- A conserved splice variant of NaV1.8 voltage-gated sodium channel from human dorsal root ganglion neurons

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