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Acta Physiologica Congress

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Acta Physiologica 2009; Volume 195, Supplement 669
The 88th Annual Meeting of The German Physiological Society
3/22/2009-3/25/2009
Giessen, Germany

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    G
    Gabel G.- Ruminal epithelial cells express a conductance for propionate
    Gabriel H.-J.- Neurometabolic coupling and oxygen demands during gamma oscillations in the hippocampus
    Gadiraju K.- Hypoxia-induced ATP release protects human endothelial cells against apoptosis via autocrine P2Y2 receptor-mediated MEK/ERK signaling
    Gajda M.- Gait abnormalities as an indicator for pain or structural joint damage in antigen-induced arthritis of the rat
    Garaschuk O.- Imaging neuronal networks in aging and diseased brain
    Garbe S.- Improvement of vessel graft storage in a new preservation solution on human internal mammary artery (HIMA)
    Gassner B.- Atrial natriuretic peptide stimulates microvascular endothelial permeability
     - The ANP/cGMP/cGMP-dependent protein kinase pathway counteracts angiotensin II-stimulated calcium mobilization in cardiac myocytes
     - Regulation of guanylyl cyclase-A, the receptor for atrial natriuretic peptide, by alternative splicing
    Gatidis S.- Suicidal erythrocyte death associated with cholestasis
    Gattenlohner S.- Dysregulation of hypothalamic-pituitary-adrenal hormone secretion in SPRED2-deficient mice
    Gavrilova-Ruch O.- Modulatory function ofPI3K in mu-opioid inhibition of voltage-gated calcium channels in nociceptive neurons
    Gaynullina D.- The role of mitogen-activated protein kinases in the contraction of arterial smooth muscle
    Gazinski A.- Regulation of guanylyl cyclase-A, the receptor for atrial natriuretic peptide, by alternative splicing
    Gebhardt C.- Electrophysiological properties of AMPA receptor mediated currents in tumor cells
    Gehring E.-M.- Regulation of the EAAT3 by PIKfyve
    Geiger C.- Parvovirus B19 protein NS1 inhibits Na+/H+ exchanger
     - Azathioprine favorably influences the course of malaria
    Geiger J. R.- Wednesday, March 25, Hall 5Oral SessionVoltage-dependent channelsChairpersons: I. Dietzel-Meyer (Bochum)T. Noack (Rostock) Energy efficient propagation of action potentials in hippocampal mossy fibers
    Gekle M.- Direct interaction of mineralocorticoid receptor and EGF receptor
     - Inhibition of cyclooxygenases positively influences proximal tubular cell impairment in an in vitro model of renal ischemia and reperfusion.
     - Fibrosis mediated by aldosterone interaction with a second agonist in cultured fibroblasts of adult rat hearts
     - The influence of aldosterone and NaCl on vascular smooth muscle cells
     - Acidosis-induced activation of ERK1/2 and p38 kinases in rat prostate cancer cells (AT1)
     - Acidosis modulates invasiveness of rat prostate cancer cells (AT1) via MAPK
     - COX-inhibition restores renal organic anion transport and positively influences renal outcome in a rat model of ischemic acute kidney injury
     - Impact of the metabolic tumor microenvironment on activity and expression of the multidrug resistance-related protein 1 (MRP1)
    Genchev B.- Ileal smooth muscle contractile activity of neonatal mice is less sensitive to cAMP/PKA than to cGMP/PKG signaling
    Genrich G.- Transversal coordination of spontaneous activity in smooth muscle
    Georgi M.- Ruminal epithelial cells express a conductance for propionate
    Georgieff M.- Monday, March 23, Audimax, Poster Area BPoster Session: Neuroprotection and hypoxiaModerators: D. Katschinski (Gttingen)U. Schrder (Magdeburg) TASK2 potassium channels are important determinants for central respiratory adaptation to hypoxia
    Gereke M.- Preserved abundance but functional dysregulation of Na+/H+ exchanger isoform NHE3 in the small and large intestine in CD45RBhigh transfer colitis mice with diarrhea
    Gerich F. J.- Enhanced hypoxia susceptibility in hippocampal slices from a mouse model of Rett Syndrome
    Gerich F.J.- H2O2-mediated modulation of cytosolic signaling and organelle function in rat hippocampus
    Gericke A.- Impact of M3 and M5 acetylcholine receptors on cholinergic dilatation of mesenteric arteries in genetically modified mice
    Gerlach M.- Glycogen synthase kinase 3-beta (GSK3) forms multiple protein complexes
    Gerling A.- The ANP/cGMP/cGMP-dependent protein kinase pathway counteracts angiotensin II-stimulated calcium mobilization in cardiac myocytes
    Gerstberger R.- Spatiotemporal activation of the transcription factor NF-IL6 in the rat brain during systemic inflammation
     - Tuesday, March 24, Audimax, Poster Area DPoster Session: Central homeostatic regulationModerators: H. Braun (Marburg)R. Gerstberger (Giessen) Activation of (non-)nitrergic hypothalamic MnPO neurons due to systemic thermal and osmoregulatory stimulations in the rat
     - The Organum Vasculosum Laminae Terminalis (OVLT) as a central nervous sensor for putative exogenous and endogenous pyrogens
     - The role of peripheral and central cyclooxygenase products in the manifestation of brain-controlled sickness responses during localized inflammation induced by macrophage-stimulating lipopeptide-2
     - Fever, sickness behavior and circulating cytokines in response to macrophage-activating lipopeptide-2 and lipopolysaccharide in toll-like receptor-2-deficient mice and CD36-deficient rats
     - LPS, MDP and FSL-1 induced cellular activation in rat area postrema microglial cells
     - Purinoceptor mediated signaling in neuronal and glial cells of the rat hypothalamic median preoptic nucleus
     - Functional expression of the apelin-12 receptor protein APJ in rat hypothalamic nuclei (PVN and MnPO) involved in body fluid homeostasis and temperature regulation
    Gerstl R.- Monday, March 23, Hall 4Oral SessionVascular inflammation: Basic aspectsChairpersons: H.-J. Schnittler (Dresden)B. Walzog (Mnchen) The mammalian actin binding protein 1 (mAbp1) is required for firm arrest and intraluminal crawling of neutrophils during the acute inflammatory response
    Gessner G.- Functional impact of the S6-RCK linker in BK channels
    Gestreau C.- Monday, March 23, Audimax, Poster Area BPoster Session: Neuroprotection and hypoxiaModerators: D. Katschinski (Gttingen)U. Schrder (Magdeburg) TASK2 potassium channels are important determinants for central respiratory adaptation to hypoxia
    Getty J.- The role of SGK1 in the glucocorticoid-induced activation of the -Enacgene promoter
    Ghanem A.- Endurance training in heterozygous ILK-deficient mice induces a hypertrophic cardiomyopathy
    Gier B.- Limiting KATP channel activity leads to upregulation of antioxidant enzymes and protection of pancreatic beta cells against oxidative stress
    Giordano E.- Monday, March 23, Hall 2Keynote Lecture IPolyamine metabolism, NO, and myocardial hypertrophyChairpersons: R. Meyer (Bonn)K.-D. Schlter (Giessen) Polyamines and cardiac hypertrophy
    Gloe T.- Proteolytic fragmentation of laminin modulates endothelial proliferation and differentiation via induction of oxygen radical formation and anoikis
     - Elastase treatment induces v3 integrin dependent activation of focal adhesion complexes
    Godecke A.- Wednesday, March 25, Hall 4Oral SessionEndothelial cell biologyChairpersons: M. Cattaruzza (Heidelberg)T. Noll (Giessen) The cardiac ankyrin repeat protein (CARP) interacts with cytoplasmic -actin in migrating endothelial cells
     - Glycogen synthase kinase 3-beta (GSK3) forms multiple protein complexes
     - Tuesday, March 24, Audimax, Poster Area APoster Session: Ca? and energy homeostasisModerators: U. Flgel (Dsseldorf)K.-D. Schlter (Giessen) HL-1 cardiomyocytes display isoform-specific functions of Akt1 and Akt2
     - Identification of protein interactions of AKT2 via TAP and MS
     - Impaired cardiac function in old but not in young mice after IGF1-receptor knockout
    Goegelein H.- Monday, March 23, Audimax, Poster Area APoster Session: Cardiomyocyte membrane potential regulationModerators: T. Baukrowitz (Jena)R. Meyer (Bonn) Viable heart slices: Action potential recordings from atrial and ventricular tissues
    Goettsch W.- Glucose-dependent regulation of chicken ovalbumin upstream promoter-transcription factor II (COUP-TFII) in human endothelial cells
     - Chicken ovalbumin upstream promoter-transcription factor II (COUP-TFII) mediated downregulation of arterial transcription factor Hey2 in human endothelial cells
    Goldstein J.- Preserved abundance but functional dysregulation of Na+/H+ exchanger isoform NHE3 in the small and large intestine in CD45RBhigh transfer colitis mice with diarrhea
    Gollasch M.- TRPC1 suppresses the Ca2+ permeability in heteromeric channel complexes without effects on arterial tone
     - Novel interaction between P450 eicosanoidsandendothelial nitric oxide in thecontrol arterial tone in mice
    Gomez R. A.- Kidney-specific deficiency of PPAR results in increased mouse renin production
    Gomez-Sanchez C.- Monday, March 23, Hall 1Main SessionPhysiology and pathophysiology of K2P -channelsSymposium of the Working Group Heart and Circulation PhysiologyChairpersons: J. Daut (Marburg)R. Warth (Regensburg) Invalidation of TASK1 K+ channels disrupts adrenal gland zonation and mineralocorticoid homeostasis
    Goodenough D. A.- Extracellular Ca2+ regulates paracellular permeability in the thick ascending limb of mouse kidney
    Gorji A.- Spreading depression triggers epileptiform activity in combined amygdala-hippocampus-neocortex tissues
     - The effect of DC potential shifts associated with quenching thirst on neuronal network activities
    Gorlach A.- Thrombin activates NOX1 involving Gi and Rac1 in pulmonary artery smooth muscle cells
     - PDE2 mediates redox-sensitive endothelial cell proliferation and angiogenesis by thrombin via Rac1
     - Expression of NADPH oxidase components during early mouse embryo development
    Gotz F.- Ca2+-dependent functions in peptidoglycan-stimulated mouse dendritic cells
    Gourine A.- Purinoceptor mediated signaling in neuronal and glial cells of the rat hypothalamic median preoptic nucleus
    Grabner A.- Regulation of human organic cation transporter 2 (hOCT2) by the new interacting partner lysosomal associated protein transmembrane 4 alpha (LAPTM4A)
    Grahammer F.- Monday, March 23, Audimax, Poster Area CPoster Session: Kidney IModerators: W. Neuhofer (Mnchen)W. H. Castrop (Regensburg) Renal function of PDK1 hypomorphic mice
    Gramkow T.- A myotonia-causing mutation in the selectivity filter of human ClC-1 channels affects slow gating
    Grassme R.- In vivo intramuscular electrical stimulation of rat triceps brachii with a multichannel electrode array
     - The back muscles of laboratory rats
    Gratchev A.- Perspectives of mathematical modeling for understanding of intracellular signaling and vesicular trafficking in macrophages
    Grebe M.- Role of extracellular RNA on vascular permeability, edema formation and myocardial infarction size
    Gregorio C. C.- Lasp-2 expression, localization, and ligand interactions:A new Z-disc scaffolding protein
    Griffiths G.- Sphingosine-1-phosphate receptors stimulate macrophage plasma membrane actin assembly via ADP release, ATP synthesis and P2X7 receptor activation
    Grimmelikhuijzen C. J. P.- The peptide-gated ion channel from Hydra magnipapillata is made of three homologous subunits
    Grisk O.- Amiloride potently lowers arterial pressure in Cyp1a1ren-2 transgenic rats without significant effects on small artery function
     - Monday, March 23, Hall 3Oral SessionRenal transport IChairpersons: C. Wagner (Zrich, CH)R. Warth (Regensburg) Cyclosporine A-induced increases of renal and hepatic MDR1 expression do not depend on renal MRP2
     - Unusual role of Kv2 channels in rat posterior cerebral small arteries
     - Superoxide formation in human intrarenal arteries is mainly due to NADPH oxidase activity and contributes to endothelium-dependent vasodilation
    Grohe C.- Gender and Toll-like receptor signaling affect cardiac function in hypertrophy
     - LPS pretreatment or downregulation of TLR4-signalling induces HIF-1 accumulation and reduces cardiac ischemia-reperfusion injury in mice
    Groos S.- Sunday, March 22, Hall 4Oral SessionIntestinal transportChairpersons: M. Bleich (Kiel)G. Breves (Hannover) Gastric KNCQ1 channels provide luminal K+ to the H+/K+ ATPase, whereas Kir 4.1 channels are involved in secretory membrane recycling
    Gros G.- Unstirred layer effects on red cell membrane CO2 permeability
    Groslier R.- Characterizing the pathway for nucleotide-release in renal epithelia
    Gross V.- Novel interaction between P450 eicosanoidsandendothelial nitric oxide in thecontrol arterial tone in mice
    Grossmann C.- Direct interaction of mineralocorticoid receptor and EGF receptor
     - Fibrosis mediated by aldosterone interaction with a second agonist in cultured fibroblasts of adult rat hearts
    Grun M.- Modulatory function ofPI3K in mu-opioid inhibition of voltage-gated calcium channels in nociceptive neurons
    Grunder S.- The peptide-gated ion channel from Hydra magnipapillata is made of three homologous subunits
     - Characterization of sharkASIC1b, an ancient form of an acid-sensing ion channel
    Gruner Y.- SGK1 and PIKfyve in the regulation of the Ca2+ channel TRPV6
     - PIP5k2A-dependent regulation of the excitatory amino acid transporter EAAT3
    Grus F. H.- Impact of M3 and M5 acetylcholine receptors on cholinergic dilatation of mesenteric arteries in genetically modified mice
    Grutzner A.- Dynamic regulation of titin stiffness in the Z/I region of the sarcomere
    Gu S.- Regulation of erythrocyte survival by AMP-activated protein kinase
     - Participation of leukotriene C4 in the regulation of suicidal erythrocyte death
     - Colon tumors express functional membrane androgen receptors that trigger pro-apoptotic responses
     - Involvement of PI3K/AKT pathway in the hypoglycemic effects of saponins from Helicteres isora
    Gudermann T.- TRPC1 suppresses the Ca2+ permeability in heteromeric channel complexes without effects on arterial tone
     - Mutation of the critical histidine residue in the T1 domain of Kv2.1 prevents the heteromeric assembly of Kv2.1/Kv6.x channels
    Guenther S.- Metabolic pathways regulate P-glycoprotein gene expression via reactive oxygen species
    Guhmann M.- EazyClone: A user-friendly application for the development of cloning strategies
    Gunther J.- Influence of otoplastics or hearing impairment on auditory evoked potentials, auditory evoked magnetic fields and source localization in professional musicians from classical orchestras
    Guntinas-Lichius O.- Facial muscle activation patterns in healthy men - a multi-channel surface EMG study
    Gunzel D.- Tuesday, March 24, Hall 4Oral SessionKidney PhysiologyChairpersons: M. Gekle (Halle/Saale),F. Schweda (Regensburg) Tricellulin enhances the barrier for ions and for macromolecules depending on its localization within the tight junction
    Guo X.-H.- Tuesday, March 24, Hall 3Oral SessionCI? channels and non-selective cation channelsChairpersons: C. Fahlke (Hannover)K. Jurkat-Rott (Ulm) Cellular Na+ overload and K+-dependent depolarization indicate a nonselective cation leak
    Gupta S.- Tuesday, March 24, Audimax, Poster Area APoster Session: Kidney IIModerators: A. Kurtz (Regensburg)T. Volk (Erlangen) Organic cation transporter mediated cytotoxicity of irinotecan and paclitaxel
    Gusev K.- Angiotensin II-mediated adaptive and maladaptive remodeling of cardiomyocyte excitation-contraction coupling
    Guy N.- Monday, March 23, Hall 1Main SessionPhysiology and pathophysiology of K2P -channelsSymposium of the Working Group Heart and Circulation PhysiologyChairpersons: J. Daut (Marburg)R. Warth (Regensburg) Invalidation of TASK1 K+ channels disrupts adrenal gland zonation and mineralocorticoid homeostasis

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