Author index

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A  |  B  |  C  |  D  |  E  |  F  |  G  |  H  |  I  |  J  |  K  |  L  |  M  |  N  |  O  |  P  |  Q  |  R  |  S  |  T  |  U  |  V  |  W  |  X  |  Y  |  Z L L F. - Effect of miltefosine on erythrocytes L Dickson Suzanne - Hypothalamic Kappa Opioid Receptor Modulates the Orexigenic Effect of Ghrelin L Grieve Kenneth - Suppression of V1 feedback reveals the loss of a RF centre drive and shift in centre/surround balance in LGN cells of the awake macaque   - Visual cortical feedback modulates LGN bursting in the detection of a novel stimulus in an attended location. LA GRUA G - Is there any benefit for experienced dancers in common upright stance? La Grutta V - Effects of nitric oxide and GABA system in a rat model of temporal lobe epilepsy LA GRUTTA V - Nitric oxide GABA interaction in the rat subthalamic nucleus   - Nitric oxide-active compounds modulate the intensity of glutamate-evoked responses in the globus pallidus of the rat   - Evidences of cannabinoids-induced modulation of paroxysmal events in an experimental model of partial epilepsy in the rat   - Comparison of effects of Valproate and the newly synthesized Valproil-L-Tryptophan on epileptiform activity in rat brain slices   - Evidences of cannabinoids-induced modulation of paroxysmal events in an experimental model of partial epilepsy in the rat LA GRUTTA, FERRARO V - Microiontophoretic evidences of the effects of nitric oxide-active drugs on the discharge of substantia nigra pars reticulata neurons of the rat LA GUARDIA M - Nutritional and psychological therapies in the treatment of obesity: preliminary findings   - Antiproliferative and proapoptotic activities of hydroxytyrosol derivatives on human promyelocytic leukemia cell lines LA GUARDIA M - Analysis of total antioxidant capacity and total phenolic content during ripening of Sicilian red grapes   - Polyphenolic compounds of red wine: relationship between antioxidant capacity and chemical structure   - Extra virgin olive oil, Nutritional quality related to Jaen index   - Flavonols: relationship between pH and antioxidant activity   - Cytotoxic effects of polyphenols from wastewater of extra virgin olive oil on human HL60 and K562 cell lines   - Study of the physiological effects of Quercetin and Kaempferol (alone or mixed) on the MnSOD enzyme   - Role of flavonols and flavan-3ols in Ca2+ homeostasis by increasing the superoxide production   - Dietary Flavonols and Flavan-3ols as modulators of superoxide radicals production: opposite dose-dependent effects   - Antioxidant effects of Epigallocatechin-3-gallate on tumor cells growth   - Relationship between the plasmatic antioxidant capacity after food intake and the ovarian cycle   - Community nutrition: knowledge, attitudes and practices of food service staff in nursing homes and long-term care facilities for the elderly   - Modulating activity of the quercetin on the superoxide dismutase   - A protocol to evaluate the antioxidant capacity by crocin bleaching assay in Pleurotus edible mushrooms   - Evolution of the phenols and unsaponifiable fractions, in extra virgin olive oil, during the ripening phase LA MARCA G - New insights into the role of the beta-adrenergic system in retinal pathophysiology LA MARCA V - Lecithin cholesterol acyltransferase esterifies 24s-hydroxycholesterol in cerebrospinal fluid   - The acute phase protein Haptoglobin affects Apolipoprotein E modulation of cholesterol homeostasis in brain   - Inflammation and neurodegeneration: new roles of the acute phase protein Haptoglobin in beta-amyloid homeostasis LA MARRA F - Constancy of oxidative stress during prolonged exercise in insulin-dependent diabetic patients LA MARRA M - Influence of auditory rhythm on movement planning   - Selective increase of distractibility in horizontal spatial dimension in older adults LA NEVE L - Flavonols: relationship between pH and antioxidant activity   - Extra virgin olive oil, Nutritional quality related to Jaen index   - Polyphenolic compounds of red wine: relationship between antioxidant capacity and chemical structure   - Relationship between the plasmatic antioxidant capacity after food intake and the ovarian cycle   - Antioxidant effects of Epigallocatechin-3-gallate on tumor cells growth   - Evolution of the phenols and unsaponifiable fractions, in extra virgin olive oil, during the ripening phase LA ROSA P - Endocrine disrupting chemicals alter estrogen receptor cellular levels LA ROSA C - The effect of Bradykinin on expression of -SMA in human lung fibroblasts cultures LA ROSA P - 17-Estradiol-induced cell proliferation requires estrogen receptor (ER) monoubiquitination   - Diverse post-translational modifications of estrogen receptor alpha cross-talk in the coordination of 17beta-estradiol-dependent cell proliferation LA ROSA S - Glutamate toxicity is a novel cause of beta-cells death and is prevented by the activity of the excitatory amino acid transporter 2 (EAAT2) in the pancreas LA ROVERE R - Satellite cells isolated from "special" muscles are special myogenic precursors LA ROVERE R - Pathological oxidative stress causes mitochondrial damage and a progressive core-like myophathy in mice lacking calsequestrin-1   - Physiological effects of GTP on M1-cortical collecting duct cell line LA SPADA G - Role of K+ and Cl- conductive pathways and K-Cl cotransport (KCC) in Regulatory Volume Decrease (RVD) of acontial nematocytes from Aiptasia mutabilis (Cnidaria, Anthozoa)   - Regulatory Volume Decrease (RVD) in jellyfish is affected by heavy metals   - Melatonin effect on adult hippocampal neurogenesis and spine density in an ovariectomized mice model   - Role of neurotransmitters in in situ discharge of nematocytes from oral arms of Pelagia noctiluca (Cnidaria, Scyphozoa)   - Genotoxicity of chemical agents and Pelagia noctiluca (Scyphozoa) venom on fish erythrocytes   - Osmotic protection against crude venom from nematocysts of Pelagia noctiluca (Cnidaria, Scyphozoa) LA VITOLA P - Alterations in retinal ganglion cell activity in a model of diabetic retinopathy LAAKSO M - Effects of reported previous physical activity on body composition and its changes during military service LAAKSONEN DE - Effects of modified protein structure on intestinal peptide release and satiety in healthy young men Laaksonen S - Expression of specific Ca2+ regulating proteins in skeletal muscle of the reindeer (Rangifer tarandus tarandus) during moderate weight loss and winter time adaptation LABOMBARDA F - Neurosteroids in neuronal damage and repair Labranche N. - EFFECTS OF DIESEL EXHAUST MICROPARTICLES ON VASCULAR ENDOTHELIAL FUNCTION   - EFFECTS OF SIDESTREAM CIGARETTE SMOKE EXTRACT AND HOMOCYSTEINE ON VASCULAR ENDOTHELIAL FUNCTION Labro A.J. - Modulation of hERG gating by a N-terminal charge cluster   - Role of the s6 c-terminus in kcnq1 channel gating Labro A.J. - A novel binding site in voltage gated potassium channels revealed by the marine toxin gambierol Labro AJ. - MOLECULAR BASIS FOR DEPOLARIZATION DEPENDENT MODULATION OF CHANNEL GATE CLOSURE IN KV CHANNELS Lacaille J-C. - Differential mechanisms of synaptic plasticity control hippocampal interneuron networks Lacampagne A. - The ryanodine receptor connection: from normal to cardiac arrhythmias   - Regionalisation of MLC-2 phosphorylation and its dephos phorylation in diseases   - Role of C-protein versus troponin I during PKA-dependent control of contractility Lachmann *P. - The human Pal3 sequence is important for the in vivo expression of human renin Lacinova L. - Role of Ca v1.2 channels for hippocampal synaptic plasticity, excitability and spatial memory   - Effect of DHP analog cerebrocrast on L-type calcium current through Ca1.2 channel V   - DHP analog cerebrocrast inhibits T-type CaV3.1 calcium channel   - Role of uppermost arginines in S4 segments of the CaV3.1 channel in channel deactivation Lacinova L - Cav1.2 calcium channels modify action potential bursts but not single action potentials in hippocampal CA1 pyramidal cells.   - Effect of phenylalkylamines and benzothiazepines on Cav1.3 calcium currents in mouse inner hair cells. Lacko E. - OPIOID AGONIST ACTIVITY OF 14-O-METHOXY-MORPHINE-6-SULFATE AND MORPHINE-6-SULFATE RELATED TO MORPHINE Lacko E. - PERIPHERAL AND CENTRAL -OPIOID ANTINOCICEPTION IN RAT VISCERAL PAIN MODEL   - ANALYSIS OF IMIDAZOLINE RECEPTORS IN THE REGULATION OF GASTRIC MOTILITY IN MICE Lackovicova Lubica - The effect of subdiaphragmatic vagotomy and chemical sympathectomy on progression of yoshida AH 130 ascitic cells in rats Lackovicova Lubica - Liver ischemia-reperfusion injury and its effect on the activity of neurons in selected brain areas LACQUANITI F - Electromyographical patterns of control of human locomotion LACROIX J - A Ci-VSP/PTEN chimera showing PI(3,4,5)P3 phosphatase activity Lacroix JJ. - MOLECULAR BASIS FOR DEPOLARIZATION DEPENDENT MODULATION OF CHANNEL GATE CLOSURE IN KV CHANNELS Lacza Z. - HUMAN ADIPOSE TISSUE DERIVED STEM CELLS IMPROVE IN VITRO THE VIABILITY OF POSTISCHEMIC CARDIOMYOBLASTS PARTIALLY VIA PARACRINE FACTORS Lacza Zs. - POLY(ADP-RIBOSE)-POLYMERASE INHIBITION IMPROVES THE SURVIVAL AND BENEFICIAL EFFECT OF THERAPEUTICALLY GIVEN CELLS IN AN IN VITRO CELL THERAPY MODEL FOR ISCHEMIA-REPERFUSION INJURY Laczko J. - NEUROMECHANICAL MODELS IN SPORT SCIENCE AND MOVEMENT REHABILITATION Ladage D - Mesenchymal Stem Cell Induce an Endothelial Activation Ladage D. - Skeletal muscle eNOS: Influence of physical exercise in non-insulin dependent typ-2-diabetic men LADEPECHE L - Dynamic cross-talk between surface glutamate and dopamine receptors: an extrasynaptic business? Ladewig T - Calcium clearance mechanisms in retinal ganglion cells   - Electrophysiological characterization of mutant CNGA3 channels associated with achromatopsia Ladilov Y. - Sodium-bicarbonate co-transporter SLC4A7 modulates the mitochondrial pathway of apoptosis in coronary cells under ischemic stress LADOR F - Cardiovascular responses to standing at the end of 35-day bed rest in humans Lador Frédéric - Maximal oxygen consumption in upright and supine posture at the end of prolonged bed rest in humans Ladwig M - Sodium balance and compartmental cation exchange in freely moving dogs Laeremans H. - TARGETING OF MYOFIBROBLASTS IN THE INFARCT AREA CAN PREVENT VENTRICULAR DILATATION AFTER MYOCARDIAL INFARCTION Laffray Sophie - GABAb impairment in the dorsal horn of neuropathic rats: possible roles for associated proteins LAFORENZA U - Effects of creatine in a rat intestinal model of ischemia/reperfusion injury   - VEGF-induced oscillations in [Ca2+]i in human endothelial progenitor cells   - Antioxidant equipment of jejunal epithelial cells: response to acute and chronic metabolic acidosis   - Small intestinal aquaporins and solute transporters are decreased in coeliac disease Lagerbohm H - Hydroxysteroid (17beta) dehydrogenase 12 is needed for normal mouse fertility LAGERSTEDT AS - Blood pressure during anaesthesia for assessment of intraoperative trauma in dogs LAGERSTEDT JO - Structural modeling and electron paramagnetic resonance spectroscopy of the Na+/H+ exchanger 1: implications for the putative ion transport site LAGHEZZA A - Effects of novel sintetic peroxisome proliferator-activation receptor (PPARs) agonist on neuronal differentiation in the human neuroblastoma SH-SY5Y cell line LAGHMANI K - Regulation of pendrin by pH: dependence on glycosylation   - Functional and structural characterisation of Cl-/HCO3- exchanger Pendrin LAGRASTA C - Cardiac Stem/Progenitor Cells of the Mammalian Heart   - Cardiac stem cell disease in diabetic cardiomyopathy: perspectives for preventing cardiac morpho-functional remodelling   - Electrical stability of infarcted rat hearts following treatment with stem cells   - Early treatment with a natural antioxidant polyphenolic compound in experimental type-1 diabetes: a new approach for preventing cardiac parenchimal and progenitor cell dysfunction in diabetic cardiomyopathy   - Repair of chronic myocardial infarction (MI) induced by mobilization of cardiac progenitor cells (CPCs) via local delivery of hepatocyte growth factor (HGF) and insulin-like growth factor-1 (IGF-1) is not proarrhythmic.   - Electromechanical Competence of the Myocardium Regenerated by Growth Factors and Cell Therapy in Ischemic Cardiomyopathy Laguna-Fernandez A - OXIDIZED LDL INCREASES PROSTANOID PRODUCTION IN CULTURED ARTERIAL ENDOTHELIAL CELLS   - PROGESTOGENS DECREASE THROMBOXANE PRODUCTION BY CULTURED HUMAN ENDOTHELIAL CELLS   - TRANSCRIPTOMIC PROFILE OF UMBILICAL ARTERIAL ENDOTHELIAL CELLS EXPOSED TO OXIDIZED LDL AND ESTRADIOL   - GENE EXPRESSION PROFILE INDUCED BY ESTRADIOL IN CULTURED HUMAN ENDOTHELIAL CELLS   - RESTORATION OF DIMETHYLARGININE-DIMETHYLAMINO-HYDROLASE ACTIVITY IN ESTRADIOL TREATED ENDOTHELIAL CELLS   - RHOA MEDIATES PROLIFERATION AND MIGRATION OF HUVEC IN RESPONSE TO ESTRADIOL LAGZDINA R - Gender differences in dietary behaviour between students with different fat percent Lahera V - THE PATHOPHYSIOLOGICAL ROLE OF ALDOSTERONE IN THE VASCULAR SYSTEM. Lahn M. - Study of intracellular chloride homeostasis in cockroach salivary glands by using two-photon fluorescence lifetime imaging microscopy (2P-FLIM) LAHOUTTE T - Mouse lacking aromatic amino acid transporter TAT1 Lahoutte T. - ANALYSIS OF BLOOD-BRAIN BARRIER PERMEABILITY FOR NANOBODIES USING MICRODIALYSIS. LAI EY - Reactivity of isolated pancreatic islet arterioles in mice Lai EY - Adenosine and Angiotensin II action on afferent arterioles Lai F.A. - Mechanisms of dysfunction in mutant ryanodine receptors in cardiac pathology LAI EY - Myogenic responses of perfused renal afferent arterioles in mice: effects of salt intake and reduced renal mass LAI E - Role of NO deficiency in salt-sensitive hypertension Lai Yu-Chiang - -Adrenoceptor stimulation potentiates insulin-stimulated PKB phosphorylation in rat cardiomyocytes via cAMP and PKA LAITALA-LEINONEN T - Imatinib mesylate disturbs bone growth and remodellation in postnatal rats Laitio R - The effect of increasing exercise intensity and adenosine receptor blockade on skeletal muscle blood flow heterogeneity in humans Lajdova I. - Investigation of the role of steroid hormone 1,25(OH)2D3 on the calcium regulation in human peripheral blood mononuclear cells Lajtos Z. - Psychophysio-immunological assessment of stress and stress management Lakatosova S - Reduced oxytocin levels in Slovak autism patients. Lakk M. - EXPRESSION OF PACAP RECEPTORS (PAC1, VPAC1, VPAC2) DURING POSTNATAL RAT RETINA DEVELOPMENT Lale N. - Renal afferent neurons exhibit an altered firing pattern in an in vitro model of kidney inflammation LALLI E - TASK3 potassium channels are involved in the regulation of aldosterone secretion in mice Lalli E. - Monday, March 23, Hall 1Main SessionPhysiology and pathophysiology of K2P -channelsSymposium of the Working Group Heart and Circulation PhysiologyChairpersons: J. Daut (Marburg)R. Warth (Regensburg) Invalidation of TASK1 K+ channels disrupts adrenal gland zonation and mineralocorticoid homeostasis   - TASK3 potassium channels are involved in the regulation of aldosterone secretion in mice   - The role of TASK3 potassium channel in the regulation of aldosterone secretion Lalo U - Quantal release of ATP at cortical synapses   - Calcium-dependent modulation of NMDA synaptic currents by P2X receptors in mouse neocortical neurons Laloglu Esra - THE INVESTIGATION OF SERUM PARAOXONASE ENZYME ACTIVITIES AND MALONDIALDEHYDE LEVELS IN BURN CASES AND HEALTHY CONTROLS Lam R - N-cadherin-mediated regulation of Kv1.5 activity   - Impaired mast cell activation in mice lacking the Serum- and Glucocorticoid-inducible Kinase SGK1 Lam RS - Impaired mast cell activation in mice lacking the calcium-activated potassium channel SK4   - Phosphoinositide 3-kinase-dependent regulation of calcium-activated potassium channels in mast cells LAM FFY - How significant is the neural contribution to anandamide-induced vasodilatation in the rat knee joint? Lam A - TPC1 is a Ca2+-permeable cation channel with ion-conducting and gating properties distinct from those of TPC2 Lam J.T. - Modelling of long QT syndrome in patient-specific induced pluripotent stem cell-derived cardiomyocytes   - In a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia dantrolene rescues arrhythmogenic RYR2 defect Lamarao I - NUTRIENT COMPOSITION AFFECTS POSTPRANDIAL GLUCOSE DISPOSAL, WHICH RELIES ON INSULIN ACTION RATHER THAN INSULIN SECRETION LAMARRA M - Distractor influence on movement trajectory Lamas JA - Regulation of the voltage gated K+ Kv7.2/3 channels by the neuronal serum-and glucocorticoids-regulated kinase 1.1 LAMB D.C - Molecular Dynamics Simulation of acidic compact state of Apomyoglobin from yellowfin tuna Lambacher Nils - Alteration of nucleocytoplasmic transport occurs during calcium-mediated cell death Lambein F. - BETA-ODAP-TRIGGERED MITOCHONDRIAL CALCIUM OVERLOAD AS AN EARLY EVENT IN EXCITOTOXICITY   - BETA-ODAP TOXICITY MAY BE RELATED TO A DISTURBANCE OF THE CELLULAR CA2+ HANDLING Lambermont B. - COMPARATIVE EFFECTS ON LV PERFORMANCE, ARTERIAL HEMODYNAMICS AND VENTRICULO-ARTERIAL COUPLING OF TWO PORCINE MODELS OF CORONARY ARTERY OCCLUSION Lambers J - Pro-survival function of TrkB: Kinase domain- dependent and -independent control of viability in renal MDCK cells Lambert C - Impact of therapeutic ROS induction on cell adhesion in solid tumors Lambert NA - Interactions between GPCR signaling components studied with fluorescence recovery after photobleaching (FRAP) Lambert S - Pharmacological characterization of the Ca2+ permeable channel TRPM3alpha2   - Characterization of TRPM3-like steroid receptors in rodent endocrine cells   - Identification of TRPM3-like currents in native murine cells   - TRPM3 is a ionotropic steroid receptor in pancreatic beta cells Lambert I. H. - HL-1mouse cardiomyocyte death after simulated ischemia and reperfusion is dependent on pHo: Roles of the Na+/H+ exchanger NHE1, and the Ca2+-independentphospholipase A2 PLA2-VI Lambert Ian H. - Swelling induced activation of the TASK-2 potassium channel by a tyrosine phosphorylation of the channel LAMBERT IH - The Role of Cellular Taurine in Cisplatin-induced Apoptosis in Ehrlich Tumor Cells   - Role of NADPH oxidases in cell volume signaling LAMBERT JJ - Neurosteroids: neurone specific endogenous modulators of the GABA-A receptor Lambert S - The fractional calcium current through fast ligand-gated TRPM channels Lambert S. - Structural basis of TRPM1 inhibition by zinc ions   - The natural enantiomer of pregnenolone sulfate activates TRPM3 channels much stronger than its synthetic counterpart   - Differentiation between homo- and heteromultimers of the ionotropic steroid receptors TRPM3 and TRPM1 LAMBIN P. - The NADPH oxidase NOX1 is a novel target of PHD2 and pVHL Lambolez B - FRET PROBES TO MONITOR THE SUBCELLULAR DYNAMICS OF SECOND MESSENGERS IN LIVING NEURONES. Lambrechts D - Dual function of VEGF as angiogenic and neuroprotective factor Lambrichts I. - ENVIRONMENTALLY RELEVANT DOSES OF CADMIUM INDUCE RENAL DAMAGE IN MICE   - Evolution of cytosolic and matrix pH in relation to mitochondrial morphology during and after recovery of metabolic inhibition, in Madin-Darby Canine Kidney (MDCK) cells Lami J. - ENDOTHELIUM-DEPENDENT EFFECTS OF MEDICINAL PLANTS FROM DEMOCRATIC REPUBLIC OF CONGO ON ISOLATED RAT AORTA   - VASORELAXANT ACTIVITY IN ISOLATED RAT AORTA OF EXTRACTS FROM PLANTS USED IN CONGOLESE TRADITIONAL MEDICINE Lamle J. - Effect of genetic ablation of the acid/base transporters pNBC1, NHE1, NHE2, and Slc26a7, on gastric epithelial functions LAMMENTAUSTA E - The reproducibility of knee cartilage magnetic resonance imaging with dGEMRIC method Lamota L - CANNABINOIDS-NICOTINE INTERACTIONS: ANIMAL MODELS OF ADOLESCENCE; IMPLICATIONS FOR FEEDING AND EMOTIONAL RESPONSES Lamp S - Na+ Ca2+ EXCHANGE PROMOTES SYNCHRONOUS TRIGGERING OF Ca2+ SPARKS IN CARDIAC MYOCYTES Lampe A. - Inherited pain: A shift in sodium channel Nav1.7 inactivation - not activation - is the electrophysiological basis for erythromelalgia in a patient carrying the mutation A1632T Lampert *A. - Oxaliplatin induces Nav1.6-mediated resurgent and persistent currents in large DRG neurons in a temperature dependent manner Lampert A - Upregulation of hippocampal sodium channel Nav1.6 expression after amygdala kindling in the mouse Lampert A. - Mutagenesis studies investigating slow inactivation of sodium channel Nav1.6   - Inherited pain: A shift in sodium channel Nav1.7 inactivation - not activation - is the electrophysiological basis for erythromelalgia in a patient carrying the mutation A1632T   - Sea Anemone toxin ATX-II increases resurgent and persistent sodium currents selectively in large diameter sensory neurons LAMPERT A - The blocking effect of the plastic-bottle-toxin bisphenol A on heart sodium channels Lampert A. - Renal afferent neurons exhibit an altered firing pattern in an in vitro model of kidney inflammation   - Voltage-gated sodium channel NaV1.6 is required for stimulus evoked repetitive action potential firing in response to cooling and oxaliplatin in peripheral myelinated axons   - Renal afferent neurons exhibit specific firing patterns which may result from a different expression pattern of voltage activated sodium channels LAMPRECHT G - NHERF2 PDZ-adapter determines the membrane raft association of the apical Na+/H+ exchanger NHE3 in murine small intestine   - Congenital chloride diarrhea - a Finnish disease serves as a paradigm for electroneutral NaCl absorption   - Membrane expression of deltaF508 mutant increases epithelial HCO3-secretion via functional Cl-/HCO3-exchanger(s) Lamprecht G. - Membrane expression of F508del mutant increases epithelial HCO3- secretion via functional Cl-/HCO3-exchanger(s) Lamy C. - COMPARATIVE EFFECTS OF RECENTLY DEVELOPED ANTIPSYCHOTICS AND JL13 IN A PASSIVE AVOIDANCE TASK IN MICE   - LONG-TERM EFFECTS OF JL13, A CLOZAPINE-LIKE ANTIPSYCHOTIC, ON RAT DOPAMINE RECEPTORS Lamy C. - Combined experimental and computational approaches to study the action of blockers of small conductance calcium-activated potassium (SK) channels   - BLOCK OF SK CHANNELS BY THE SIGMA AGONIST 1,3-DI-O-TOLYL-GUANIDINE: EVIDENCE FOR A NOVEL SITE OF ACTION FOR SK BLOCKERS   - Combined experimental and computational approaches to study the action of blockers of small conductance calcium-activated potassium (SK) channels LAN WEI - Oxidative stress underlies sudden death in Calsequestrin-1 knockout (CASQ1-null) mice suffering of Malignant Hyperthermia (MH) and Environmental Heat Stroke (EHS) Lancaster C.S. - Renal secretion of creatinine is mediated by organic cationic transporters Lancien Frédéric - CENTRAL ADMINISTRATION OF TROUT PITUITARY ADENYLATE CYCLASE - ACTIVATING POLYPEPTIDE (PACAP) AND VASOACTIVE INTESTINAL PEPTIDE (VIP) DECREASE BAROREFLEX SENSITIVITY IN TROUT: A TRANSFER FUNCTION ANALYSIS Lancien Frédéric - CONTRASTING VENTILATORY ACTIONS OF CENTRALLY ADMINISTERED TACHYKININS, PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE AND VASOACTIVE INTESTINAL PEPTIDE IN TROUT Land SC - Induction of lung fibroblast-myofibroblast differentiation by interleukin-6 involves mTOR- dependent regulation of PPAR[gamma].   - Modulation of dexamethasone-evoked a-ENaC expression by the mammalian target of rapamycin (mTOR) Land S. - Dexamethasone-induced activatin of epithelial Na+ channels does not correlated with increase phosphorylation of endogenous Nedd-4/2 in H441 human airway epithelial cells Land SC - Control of HIF-1 and vascular signalling in fetal lung involves cross-talk between mTORC1 and the FGF-10/FGFR2b/Spry2 airway branching periodicity clock. LANDINI L - Magnetic resonance imaging with hyperpolarized 13C-pyruvate to study carbohydrate metabolism in vivo LANDON CS - A new radio-telemetry (RT) technique to study the respiratory pattern prior to seizures in awake rats exposed to hyperbaric oxygen (HBO2): an approach to prevent CNS oxygen toxicity Landrichinger *J. - Noradrenalin and galanin modulate phagocytosis in microglia Landry Marc - GABAb impairment in the dorsal horn of neuropathic rats: possible roles for associated proteins LANDRY DW - Sildenafil improves synaptic function, memory and Amyloid-beta load in an Alzheimer Mouse Model Landsberger *M. - Endothelin receptor inhibition and its effects on LOX-1 expression in amiodarone-induced lung fibrosis in rat LANDWEHRMEYER GB - Altered kinetics of Ca2+ transients in skeletal muscle fibres of a mouse expressing an N-terminal mutant huntingtin fragment LANFERMANN J - The heart rate dependent regulation of the QT interval in freely moving guinea pigs LANFRANCHI G - Analysis of transcriptional profiles at single-fiber level in skeletal muscles LANFRANCONI F - Central and peripheral limitations to oxidative metabolism following a 35-day bed rest   - Differences in the pulmonary response to work and to hypobaric hypoxia Lanfumey L. - Partial serotonergic lesion attenuates REM sleep reduction by citalopram Lang C - Oxidant sensitive anion and organic osmolyte channels in human K562 cells   - Accelerated clearance of malaria infected sickle cell trait erythrocytes   - Osmolyte channels in malaria-infected erythrocytes   - Influence of iron deficiency on the course of malaria in Plasmodium berghei infected mice   - Inhibition of eryptosis and intraerythrocytic growth of Plasmodium falciparum by flufenamic acid Lang D - Mechanisms of Ca2+/calmodulin-regulation of hOCT2 Lang E - Curcumin induced suicidal erythrocyte death Lang F - Curcumin induced suicidal erythrocyte death   - Phosphoinositide 3-kinase-dependent regulation of Kv channels in dendritic cells   - PGE2 dependent erythrocyte death blunts malaria in annexin A7 deficient mice   - Colchicine analogs inhibit channel-induced eryptosis   - Role of Serum- and Glucocorticoid-inducible kinase 1 SGK1 in the regulation of dendritic cell channel activity and function   - Erythrocytes from erythropoietin-overexpressing mice are sensitized to suicidal erythrocyte death   - Grb-adaptor proteins modulate Kir2 channels   - Effects of Gum Arabic (Acacia Senegal) on water and electrolyte balance in healthy mice   - Differential effect of the serum and glucocorticoid kinases 1 and 3 on the sodium-dependent dicarboxylate cotransporter 3 (NaDC3)   - Regulation of TRPV5 channels by WNK isoforms   - Oxidant sensitive anion and organic osmolyte channels in human K562 cells   - Influence of IGF1 and glucocorticoids on survival of insulin secreting cells   - Regulation of KCNQ4 Potassium Channels by SGK1 in Oocytes   - Impaired intestinal NHE3 activity in the PDK1 hypomorphic mouse   - SGK1 dependent upregulation of intestinal SGLT1 and NHE3 by dexamethasone   - The serum and glucocorticoid inducible kinase SGK1 mediates salt sensitivity of glucose tolerance   - Blunted DOCA/high salt induced albuminuria and renal tubulointerstitial fibrosis in SGK1 knockout mice   - Stimulation of the creatine transporter SLC6A8 by the protein kinases SGK 1 and SGK3   - GLUT4 glucose transporter abundance is affected by the serum and glucocorticoid inducible kinase SGK1   - Accelerated clearance of malaria infected sickle cell trait erythrocytes   - Amyloid induced suicidal erythrocyte death   - Regulation of Endocytic Recycling of KCNQ1/KCNE1 Potassium Channels   - Analysis of potent Kv1.5 channel inhibitors   - PI3-Kinase-dependent electrogenic intestinal transport of glucose and amino acids   - Functional Significance of the Kainate Receptor GluR6 M836I Mutation that is Linked to Autism   - N-cadherin-mediated regulation of Kv1.5 activity   - Mechanisms involved in SGK1 dependent regulation of glucose transporter GLUT4   - Phosphoinositide 3-kinase-dependent regulation of calcium-activated potassium channels in mast cells   - Structural Determinants of KCNE1-Modulation of Kv7.1 (KCNQ1) Gating   - Inhibition of Na+/H+ Exchanger Activity by Parvovirus B19 Protein NS1   - SGK1 kinase upregulates glucose transporter GLUT1 activity and expression   - Inhibition of erythrocyte cation channels and phosphatidylserine exposure by catecholamines   - Glucocorticoid stimulation of gastric acid secretion in mice lacking the serum and glucocorticoid inducible kinase SGK1   - Mechanisms underlying the regulation of neuronal and glial amino acid transport by the serum and glucocorticoid inducible kinase SGK   - TRPC6 contributes to the erythrocyte cation leak   - Ca2+-induced phosphatidylserine exposure and enhanced clearance of erythrocytes in iron deficiency   - Posttranslational regulation of excitatory amino acid transporter EAAT2 by coexpressed ubiquitin ligase Nedd4-2, SGK isoforms and PKB/Akt   - Decreased cation channel activity and blunted channel-dependent eryptosis in fetal erythrocytes   - Stimulation of eryptosis by lipoxygenase inhibitors nordihydroguaiaretic acid and Bay-Y5884   - Physical performance of mice lacking serum and glucocorticoid inducible kinase SGK1   - The diverse functions of the serum and glucocorticoid inducible kinase SGK1   - EAAT4 phosphorylation at the SGK1 consensus site is required for kinase dependent transport modulation   - Impaired mast cell activation in mice lacking the calcium-activated potassium channel SK4   - Mechanisms underlying anti-A-IgG antibody induced suicidal erythrocyte death   - Impaired mast cell activation in mice lacking the Serum- and Glucocorticoid-inducible Kinase SGK1   - Functional Coassembly of KCNQ4 with KCNE-b- Subunits in Xenopus Oocytes   - PGE2-induced apoptotic cell death in K562 human leukaemia cells through activation of TRPC7 nonselective cation channels   - Amiloride sensitive transepithelial potential in gene targeted mice lacking the Serum and Glucocorticoid inducible kinase SGK1   - Regulation of Na+K+-ATPase activity in insulin secreting cells   - Inhibition of eryptosis and intraerythrocytic growth of Plasmodium falciparum by flufenamic acid   - Role of SGK1 in glucocorticoid regulation of renal electrolyte excretion and blood pressure   - High fructose diet sensitizes blood pressure to salt intake: Resistance of mice lacking the serum and glucocorticoid inducible kinase SGK1   - Regulation of Na+/K+-ATPase by dexamethasone in insulin secreting cells through SGK1   - K+ channels, K+/H+ ATPase and SGK1 in the stimulation of gastric acid secretion by glucocorticoids   - Influence of iron deficiency on the course of malaria in Plasmodium berghei infected mice   - Osmolyte channels in malaria-infected erythrocytes   - Mitochondria-independent death receptor mediated cytosolic acidification during apoptosis of T cells   - Upregulation of HERG channels by the serum and glucocorticoid inducible kinase isoform SGK3   - Paclitaxel stimulates erythrocyte programmed cell death by a caspase-independent mechanism   - Enhanced eryptosis of red blood cells from gene targeted mice lacking the Cl-/HCO3-exchanger AE1   - Cell volume regulation and T cell survival in taurine transporter (TAUT) knock-out mice   - Dexamethasone-induced apoptosis in insulin-secreting cells: the role of calcineurin activation   - Involvement of sgk1 in volume retention induced by the PPARg-agonist pioglitazone   - Impaired intestinal and renal glucose transport in PDK1 hypomorphic mice   - Purinoceptor signalling during malaria infection   - Stargazin and SGK3 regulate GluR1 by additive mechanisms Lang KS - Cell volume regulation and T cell survival in taurine transporter (TAUT) knock-out mice   - Ca2+-induced phosphatidylserine exposure and enhanced clearance of erythrocytes in iron deficiency Lang N - NO underlies the muscarinic receptor-mediated inhibition of If in early embryonic heart cells Lang PA - Accelerated clearance of malaria infected sickle cell trait erythrocytes   - Inhibition of erythrocyte cation channels and phosphatidylserine exposure by catecholamines   - Inhibition of Na+/H+ Exchanger Activity by Parvovirus B19 Protein NS1   - PGE2 dependent erythrocyte death blunts malaria in annexin A7 deficient mice   - Ca2+-induced phosphatidylserine exposure and enhanced clearance of erythrocytes in iron deficiency   - Stimulation of eryptosis by lipoxygenase inhibitors nordihydroguaiaretic acid and Bay-Y5884   - Decreased cation channel activity and blunted channel-dependent eryptosis in fetal erythrocytes   - Mechanisms underlying anti-A-IgG antibody induced suicidal erythrocyte death   - Cell volume regulation and T cell survival in taurine transporter (TAUT) knock-out mice   - Paclitaxel stimulates erythrocyte programmed cell death by a caspase-independent mechanism Lang RE - The human erythroleukemia cell line K562 is a useful tool for investigating the function of the leptin receptor Lang C. - Effect of cyclosporine onparasitemia and survival of Plasmodium berghei-infected mice Lang E. - Enhanced suicidal death of erythrocytes in mice lacking functional mitogen- and stress-activated protein kinase MSK1   - p38 MAPK activation and function following osmotic shock of erythrocytes   - Carbon monoxide stimulates Ca2+ entry into erythrocytes triggering programmed cell death LANG F - Regulation of gastric acid secretion by PKB/Akt2   - Janus kinase 3 is activated upon energy depletion and plays role in suicidal death of energy depleted erythrocytes   - Hypothyroidism of gene targeted mice lacking KCNQ1   - Activation of membrane androgen receptors down regulates pro-survival signaling and inhibits cellular motility in colon tumor cells   - Regulation of Ca2+-induced Ca2+-current (ICRAC) by SGK1   - Downregulation of Na+-coupled glutamate transporter EAAT3 and EAAT4 by AMP-activated protein kinase   - Regulation of the glutamate transporter EAAT4 by PIKfyve   - Glycogen synthase kinase 3 in the regulation of amino acid transport   - Stimulation of Na+/Ca2+ exchangers contributes to the immunosuppressive effects of glucocorticoids and 1,25-Dihydroxyvitamin D3 in dendritic cells   - Calciuria and phosphaturia in mice expressing PKB/SGK-resistant GSK3   - Modulation of hERG by CASQ2 may impact Ethiology of Catecholamine-induced Polymorphic Ventricular Tachycardia (CPVT)   - Role of SGK1 dependent regulation of Orai1/STIM1 in migration   - Reduced muscle force and altered muscle fiber type composition in mice deficient of the serum- and glucocorticoid-inducible kinase SGK1   - Sphingomyelinase dependent apoptosis of dendritic cells following treatment with amyloid peptides   - Hyperactivity and enhanced curiosity of mice expressing PKB/SGK-resistant glycogen synthase kinase-3 (GSK3)   - Effects of LPS and dexamethasone on Na+/H+ exchanger activity in dendritic cells   - Amyloid peptide decreases Kv channel activity in dendritic cells via acid sphingomyelinase-dependent formation of ceramide Lang F. - The inflammatory chemokine CXCL16 mediates platelet activation and adhesion via PI3K/AKT signaling pathway   - Requirement of PKB/SGK-dependent GSK3 phosphorylation for stimulation of renal tubular phosphate reabsorption by dietary phosphate depletion   - Enhanced suicidal death of erythrocytes in mice lacking functional mitogen- and stress-activated protein kinase MSK1   - Regulation of Na+-coupled glucose carrier SGLT1 by Janus Kinase 2   - Ca2+ regulated actin cytoskeleton rearrangements in mast cells   - Phosphaturia in gene-targeted mice lacking functional SGK3   - Depolymerization of cortical actin in chorea-acanthocytosis   - Proteome analysis of erythrocytes lacking AMP-activated protein kinase reveals a role of PAK2 kinase in eryptosis   - SGK3-dependent regulation of voltage gated K+ channels and Ca2+ entry in dendritic cells   - Regulation of voltage-gated K+ channels by mTOR   - Glycogen synthase kinase 3 sensitive regulation of voltage gated K+ channels in dendritic cells   - SGK1 dependent stimulation of intestinal SGLT1 activity by Vitamin D   - Downregulation of NaPi-IIa and NaPi-IIb Na+-coupled phosphate transporters by coexpression of Klotho   - Akt2-dependent regulation of calcium entry and migration in dendritic cells   - Enhanced Ca2+ entry and Na+/Ca2+ exchanger activity in dendritic cells from AMP-activated protein kinase deficient mice   - Down-regulation of the renal outer medullary K+ channel ROMK by the AMP-activated protein kinase   - Serum- and glucocorticoid- inducible kinase SGK1 regulates store-operated Ca2+ entry and migration of mast cells   - Chorein-sensitive polymerization of cortical actin and suicidal cell death in chorea-acanthocytosis   - Klotho sensitivity of cardiac K+ channels   - TGFß1 and SGK1 sensitive store operated Ca2+ entry and Orai1 expression in endometrial Ishikawa cells   - Patulin-induced suicidal erythrocyte death   - PI3K-dependend translational upregulation and translocation of Orai1 following platelet activation   - SGK3 regulates Ca2+ entry and migration of dendritic cells   - Effect of lithium on mineral metabolism   - Inhibitory effect of CORM-2 on vitamin D metabolism   - Spironolactone increases renal Klotho gene expression by stimulating 25-hydroxyvitamin D3 1-alpha-hydroxylase   - Withaferin A induced erythrocyte membrane phospholipid asymmetry   - Down-regulation of the Na+ coupled phosphate transporter NaPiIIa by AMP-activated protein kinase   - B-RAF sensitivity of Na+-coupled phosphate transporter NaPiIIa   - Effect of cyclosporine onparasitemia and survival of Plasmodium berghei-infected mice   - Regulation of erythrocyte survival by AMP-activated protein kinase   - Participation of leukotriene C4 in the regulation of suicidal erythrocyte death   - Altered stress-dependent IKs channel trafficking in LQTS   - Long QT syndrome-associated mutations in the voltage sensor of IKs channels may favor early after depolarizations   - Hyperaldosteronism in Klotho-deficient mice   - Responses to diuretic treatment of SGK1 knockout mice   - PIP5k2A-dependent regulation of the excitatory amino acid transporter EAAT3   - Stimulation of the Na+-glucose cotransporter SGLT1 by AMP-activated protein kinase   - Decreased susceptibility of the PDK1 hypomorphic mouse to tumor growth upon chemical cancerogenesis   - Disruption of stimulation of glutamate receptors by a schizophrenia-associated kinase mutant   - PIKfyve-dependent regulation of the Cl- channel ClC-2   - Parvovirus B19 protein NS1 inhibits Na+/H+ exchanger   - Monday, March 23, Audimax, Poster Area CPoster Session: Kidney IModerators: W. Neuhofer (Mnchen)W. H. Castrop (Regensburg) Renal function of PDK1 hypomorphic mice   - Involvement of PI3K/AKT pathway in the hypoglycemic effects of saponins from Helicteres isora   - Colon tumors express functional membrane androgen receptors that trigger pro-apoptotic responses   - Azathioprine favorably influences the course of malaria   - Modulation of cardiac ion channels by Coxsackievirus B3   - SGK1-dependent salt appetite in pregnant mice   - Decisive role of excessive 1,25(OH)2D3 formation in the hypoglycemic effect of Klotho deficiency   - AMP-sensitive adhesion of erythrocytes to endothelial cells   - Inhibition of Kir2.1 (KCNJ2) by the AMP-activated protein kinase   - Upregulation of Na+/H+ exchanger by the AMP-activated protein kinase   - Anxiety in the Akt2 knock out mouse   - Transcriptional regulation of the Ca2+ channel Orai1/STIM1 by the serum- and glucocorticoid-inducible kinase SGK1   - Effect of bacterial lipopolysaccharide on Na+/H+ exchanger activity in dendritic cells   - Sgk1 sensitivity of Na+/H+ exchanger activity and cardiac remodeling following pressure overload   - Expression and functional significance of calcium-activated chloride channels in dendritic cells   - Mineralocorticoid receptor sensitive soft tissue calcification and early death of Klotho-deficient mice   - Effects of Gum Arabic (Acaciasenegal) on renal function in diabetic mice   - The Serum- & Glucocorticoid-inducible Kinase 1 (SGK1) influences platelet calcium signaling and function by transcriptional regulation of Orai1 expression in megakaryocytes   - Down-regulation of Kir2.1 (KCNJ2) by Klotho   - p38 MAPK activation and function following osmotic shock of erythrocytes   - Thrombin-sensitive expression of the store operated Ca2+ channel Orai1 in blood platelets   - Regulation of the glutamate transporter EAAT3 by mammalian target of rapamycin (mTOR)   - Regulation of FGF23 expression by PI3 kinase sensitive GSK3 signaling   - Effect of dexamethasone on Klotho expression in human embryonic kidney (HEK) cells   - Partial OSR1 deficiency results in phosphaturia   - PiT-1 regulates aldosterone-induced vascular osteoinductive signaling   - C-Reactive Protein-induced adhesion of eryptotic erythrocytes to endothelial cells   - Effect of honokiol on erythrocytes   - The uremic toxin acrolein promotes suicidal erythrocyte death   - Glycogen synthase kinase 3 regulates Ca2+ signalling in dendritic cells   - Upregulation of peptide transporters PepT1 and PepT2 by Janus kinase JAK2   - AMP-activated kinase participates in cell volume regulation   - Stimulation of platelet apoptosis by balhimycin   - Downregulation of Kv1.5 K+ Channels by the AMP-Activated Protein Kinase   - Stimulation of the Na+-coupled glucose transporter SGLT1 by B-RAF   - Up-regulation of Na+-coupled glucose transporter SGLT1 by caveolin-1   - SGK1-dependent downregulation of Foxo3a promotes growth of colon tumors   - Effects of glucocorticoids on regulation of cytosolic Ca2+ activityin dendritic cells   - Non-selective cation channel-mediated Ca2+-entry, modulation of calcium/calmodulin-dependent kinase II (CaMKII) and G2/M cell cycle arrest in irradiated K562 leukemia cells   - Involvement of phosphoinositide dependent kinase PDK1 in the regulation of channel activity in pancreatic beta cells by epinephrine   - Blunted activation of mast cells in mice lacking the serum- and glucocorticoid-inducible kinase SGK3   - SGK1 and PIKfyve in the regulation of the Ca2+ channel TRPV6   - SGK1-dependent regulation of intestinal peptide transport   - Energy sensitivity and Na+/K+ATPase regulating potency of Janus kinase 2   - Role of acid sphingomyelinase in the regulation of mast cells cell function   - Altered regulation of cytosolic Ca2+ concentration in dendritic cells from klotho hypomorphic mice   - Akt2-dependent transcriptional factor ETS1 regulates expression of IP3 receptor 2 in dendritic cells   - AMP-activated protein kinase regulates hERG potassium channel   - Janus kinase 3 regulates phosphate homeostasis   - Effect of Janus kinase 3 on peptide transporter PepT1   - Inhibition of colonic tumor growth by selective SGK1 inhibitor EMD638683   - Up-regulation of the large conductance voltage- and Ca2+-activated K+ channels by Janus-activated kinase JAK2   - Actin depolymerization and impaired degranulation of platelets from patients with Choreoacanthocytosis   - Dynamic adhesion of eryptotic erythrocytes to endothelial cells via CXCL16/SR-PSOX   - SGK1 and ion channels in the regulation of platelet migration   - Up-regulation of Kir2.1 (KCNJ2) by protein kinase B and PIKfyve   - Stimulation of the amino acid transporter ASCT2 by JAK2   - Stimulation of the amino acid transporter SLC6A19 by PKB/Akt   - Downregulation of Klotho expression by dehydration   - Spermine regulates cation channels activity in human erythrocytes   - Regulation of Orai by AMPK   - Fas apoptotic inhibitory molecule- 3(FAIM3) /TOSO regulates phenotype, calcium entry upon TCR activation and perforin expression in CTLs   - Regulation of basal gastric acid secretion by the glycogensynthase kinase GSK3   - Regulation of KCNQ1/KCNE1 by -catenin   - Monday, March 23, Hall 5Oral SessionRenal transport IIChairpersons: J. Leipziger (Aarhus, DK)E. Schlatter (Mnster) Calciuria and phosphaturia in mice expressing PKB/SGK-resistant GSK   - Ca2+-dependent functions in peptidoglycan-stimulated mouse dendritic cells   - Regulation of calcium signaling in dendritic cells by 1,25-dihydroxyvitamin D3   - Endothelin receptor stimulation protects from suicidal erythrocyte death   - Role of APC in erythrocte survival   - Suicidal erythrocyte death associated with cholestasis   - Regulation of the EAAT3 by PIKfyve   - Carbon monoxide stimulates Ca2+ entry into erythrocytes triggering programmed cell death   - Apigenin-induced suicidal erythrocyte death   - SGK1 dependend NF-kB signalling controls Ca2+ entry and affects cellular functions via ORAI1 and STIM1   - Niflumic acid facilitates thapsigargin-induced apoptosis in K562 cells by activation of Ca2+-activated potassium channels (SK4) and inhibition of store-operated calcium channels   - Stimulation of platelet apoptosis by peptidoglycan fromStaphylococcus aureus113   - The acid sphingomyelinase (aSM) regulates platelet degranulation and thrombus formation   - Enhanced catecholamine release in mice expressing PKB/SGK-resistant GSK3   - OSR1-sensitive regulation of Na+/H+ exchanger activity in dendritic cells   - Toll like receptor sensitive cell volume and H+ regulation in Dendritic Cells   - Effect of amyloid peptides on voltage gated potassium channels in dendritic cells   - Aldosterone dependent Tgf-beta activity in klotho-deficient mice   - Adhesion of annexin 7 deficient erythrocytes to endothelial cells   - Impaired platelet Ca2+ signaling and thrombus formation due to excessive 1,25 (OH)2 Vitamin D concentrations in Klotho-deficient mice   - Skepinone-L, a novel potent and highly selective inhibitor of p38 MAP kinase, effectively impairs platelet activation and thrombus formation   - Triggering of suicidal death and endothelial adhesion of erythrocytes following dehydration   - Annexin 7 in the Regulation of Gastric Acid Secretion   - Dexamethasone activates the cardiac sodium/hydrogen exchanger 1 via Sgk1   - OSR1-sensitive intestinal Na+ transport   - Serum- and glucocorticoid-inducible kinase SGK1 regulates reorganization of actin cytoskeleton in mast cells   - Lack of the serum- and glucocorticoid-inducible kinase SGK1 improves muscle force characteristics and attenuates fibrosis in dystrophic mdx mouse muscle.   - Regulation of Klotho expression by PI3 kinase signaling   - PKB/SGK-sensitive phosphorylation of GSK3 in the regulation of lymphocyte function   - Regulation of Na+-coupled glucose carrier SGLT1 by human papilloma viral protein HPV-18E6   - SGK1-mediated negative feedback regulation of maturation and IL-12 production in dendritic cells   - SDF-1 mediated platelet migration is regulated by the PI3K downstream effector SGK1   - Thymoquinone-induced platelet apoptosis   - Functional Analysis of a Novel I71N Mutation in the GJB2 Gene Causing Autosomal Recessive Hearing Loss   - The serum- and glucocorticoid-inducible kinase-1 (SGK1) regulates expression and function of membrane androgen receptors (mAR) as well as migration in tumor cells Lang Florian - Interaction of Bax with a mitochondrial potassium channel is crucial for its action in apoptosis Lang K. - PKB/SGK-sensitive phosphorylation of GSK3 in the regulation of lymphocyte function Lang L.J. - Paracellular transport of a hydrophilic opioid receptor agonist is increased by chitosan Lang P. - Small heat shock proteins associate under stress conditions with the elastic titin filaments and provide protection from aggregation   - Cellular proton buffer capacity revisited: A study in Xenopus oocytes   - Dynamic regulation of titin stiffness in the Z/I region of the sarcomere   - Protein phosphatase-5 is a novel titin ligand which dephosphorylates cardiac titin and reduces passive myocyte stiffness   - Determinants of transversal stiffness of single muscle sarcomeres by AFM Lang P. A. - Parvovirus B19 protein NS1 inhibits Na+/H+ exchanger Lang S - Common genetic variants of the human L-type calcium channel Cav1.3 associate with impaired insulin secretion Lang S. - The role of the Leucine-Rich Repeat Kinase 2 (LRRK2) in development and severity of Inflammatory Bowel Disease (IBD) Lang U. - Anxiety in the Akt2 knock out mouse   - Effect of lithium on mineral metabolism   - Enhanced catecholamine release in mice expressing PKB/SGK-resistant GSK3 Lang U. E. - Regulation of the EAAT3 by PIKfyve   - PIP5k2A-dependent regulation of the excitatory amino acid transporter EAAT3 LANG UE - Hyperactivity and enhanced curiosity of mice expressing PKB/SGK-resistant glycogen synthase kinase-3 (GSK3)   - Regulation of the glutamate transporter EAAT4 by PIKfyve Langa E - Biological activity of Borago officinalis on isolated rat smooth muscle and antioxidant capacity   - Effects of extracts obtained from wine by-products on isolated rat duodenum Langbein *H. - High-fat diet induces endothelial dysfunction in C57BL/6J mice Langbein H. - Regulation of NADPH oxidase 4 in endothelian cells under hypoxia   - Regulation of NADPH oxidase 4 and transcription factor NRF2 by arterial flow in endothelial cells: a novel feedback mechanism   - NADPH oxidase 4 is upregulated under chronic hypoxia by a HIF-independent mechanism in endothelial cells   - Expression pattern of scavenger receptor LOX-1 in metabolic active tissues after high-fat diet feeding   - Optical Coherence Tomography as a Novel Method to Measure Endothelial Dysfunction in Mice In Vivo after High-Fat Diet   - NADPH oxidase NOX4 is regulated by the main mediator of cellular adaptation to redox stress NRF2 Lange A - K channel structure Lange N - Exercise-Induced Angiogenesis is Missing in Heterozygous MnSOD-Knockout Mice   - Exercise-induced alterations of peroxiredoxin-isoforms in skeletal muscle of wild-type and heterozygous MnSOD-deficient mice Lange S - Are there conformation variants of antisecretory factor/S5a in the CNS?   - AMP-kinase increases cardiomyogenesis in mouse embryonic stem cell-derived embryoid bodies.   - Investigations on vasculogenesis and smooth muscle differentiation of mouse embryonic stem cells Lange Christina - THE HIF-EPO SYSTEM IN RETINAL DEVELOPMENT AND NEUROPROTECTION Lange M. - “Does a release of NT-3 from glial cells contribute to sodium current up-regulation by thyroid hormone in postnatal rat hippocampal cultures?” Lange S. - Signal transduction ofplatelet-derived growth factor BB action enhancing vasculogenesis of embryonic stem cells Lange T. - TRPV4 channels in mouse skeletal muscle: their role for Ca2+ homeostasis, muscle fatigue and motor function   - Functional TRPV4 channels are expressed in mouse skeletal muscle and can modulate background Ca2+ entry and muscle fatigue Langehanenberg P - Cell volume regulation in IMCD-cells by aquaporin-2 monitored with digital holographic microscopy Langehanenberg P. - Atrial natriuretic peptide antagonizes the vasopressin mediated water permeability in inner medullary collecting duct cells via proteinkinase G Langeluddecke *C. - The lipocalin-2 (24p3/NGAL) receptor is expressed in mouse colon and mediates endo- and transcytosis of metal-peptide complexes Langeluddecke C. - Cyclosporin A, but not FK506, induces osmotic lysis of pancreas zymogen granules, intra-acinar enzyme release, and lysosome instability by activating a K+ channel. Langelüddecke C. - Regulation of 24p3 and 24p3 receptor expression by tonicity in rodent renal inner medullary collecting duct cells: Possible involvement of Wnt/β-catenin signaling Langelueddecke C. - The role of AMPK in the regulation of insulin secretion and proliferation in INS-1E rat insulinoma cells   - Resveratrol inhibits stimulus-secretion-coupling and induces apoptosis in INS-1E rat insulinoma cells Langelueddecke Christian - The functional role of the non-gastric H+/K+-ATPase ATP12A (ATP1AL1) as anti-apoptotic ion transporter Langenbruch L - Establishing a bioluminescence resonance energy transfer assay for the mineralocorticoid receptor Langenhan T. - Genetic expression of an active zone peptide as a tool to induce cell-specific synaptic depression in vivo   - Optical analysis of presynaptic proteins at the Drosophila neuromuscular junction   - Using genetically encoded botulinum toxin light chains to analyze synaptic function in Drosophila sensory cells   - Human CORD-7 RIM-mutation alters presynaptic function in Drosophila   - Introducing ultra-sensitive Channelrhodopsin-2 variants to evoke neuronal activity in vivo   - Characterisation of dCIRL in Drosophila melanogaster Langer M - Fast kinetics of single mechanotransducer channels in mammalian outer hair cells by AFM and patch clamp Langer MG - Fast kinetics of single mechanotransducer channels in mammalian outer hair cells by AFM and patch clamp Langer H. - The uremic toxin acrolein promotes suicidal erythrocyte death Langeslag M. - Reduced mechanical hypersensitivity in conditional gp130 knock-out mice - investigating the cellular and molecular background Lange-Sperandio B. - Leukocyte rolling in vivo is regulated by RAGE Langhans W. - HOMEOSTATIC CONTROL MECHANISMS Langhans Wolfgang - THE ROLES OF GUT PEPTIDES AND INFLAMMATION IN THE CONTROL OF EATING   - PARACRINE AND ENDOCRINE EFFECTS OF PERIPHERAL GLP-1 ON EATING Langhorst MF - Activation of T Cell Calcium influx through TRPM2 channels by the second messenger ADP-ribose Langhorst H. - Characterization of the epithelial sodium channel delta subunit in human nasal epithelium Langmeier M - Effect of the perinatal alcohol abuse on the development of neuronal population in rats   - Density of nitrergic neurons in the brain of rats exposed to intermittent hypobaric hypoxia after magnesium administration   - Nicotine and Kainic acid administration - changes in the density of hippocampal neurons Langwieser N. - Role of Ca v1.2 channels for hippocampal synaptic plasticity, excitability and spatial memory Lanner JT - Altered non-selective cation currents in type 2 diabetic cardiomyocytes LANNER J - Calcium handling in diabetes LANNER JT - AICAR prevents heat induced malignant hyperthermia in RyR1 mutant mice independent of AMPK activation LANNI A - 3,5-diiodo-L-thyronine (T2) modulates the expression of genes of lipid metabolism in a rat model of fatty liver   - Influence of 3,5-diiodo-L-thyronine on skeletal muscle lipid metabolism.   - Rapid effect of 3,5-diiodo-L-thyronine on skeletal muscle mitochondrial fatty acid oxidation rate and thermogenesis   - Rapid activation by 3,5,3-L-triiodothyronine of AMPK/ACC and Akt/PKB signaling pathways in rat gastrocnemius muscle in vivo   - 3,5-diiodo-L-thyronine protects against high fat diet induced insulin resistance and glucose intolerance in rats   - 3.5-diiodo-L-thyronine improves mitochondrial function in nonalcoholic steatosis through the stimulation of SIRT3 mitochondrial targets   - A combined Blue Native- and 2D-electrophoresys approach to study rat fatty liver proteome following 3,5-diiodothyronine treatment   - Role of uncoupling protein 3 in the translocation of lipid hydroperoxide across the mitochondrial inner membrane and in inducing lipid hydroperoxide-dependent mitochondrial uncoupling   - Role of AMPK in the organ-specific responses to 3,5-diiodo-L-thyronine in high-fat diet-fed rats   - Prevention of diet-induced insulin resistance by3,5-diiodo-L-thyronine in rats involves SIRT1   - High fat diet-induced insulin resistance: effects of 3,5-diiodo-L-thyronine on muscle mitochondrial proteome and function. LANNI I - Responsiveness to NGF is reduced in sympathetic neurons of mdx mice, affecting axon outgrowth and regeneration both in vivo and in vitro   - Lack of dystrophin affects axon regeneration in vivo and neurite outgrowth in vitro Lanteri *P. - Evaluation of bone metabolism in elite cyclists during the Giro dItalia three weeks-long stage race Lanteri P. - Relationship between osteocalcin, undercarboxylated osteocalcin and markers of energy status in elite cyclists during the Giro dItalia three weeks-long stage race Lantos J. - EFFECT OF KIDNEY ISCHEMIC POSTCONDITIONING AND PHARMACOLOGICAL POST-TREATMENT ON IN HEALTHY AND DIABETIC RATS LANTTO VE - Photoplethysmographic measurement and pulse wave analysis LANVERS-KAMINSKY C - Organic cation transporter 2 mediates cisplatin-induced oto- and nephrotoxicity and is target for protective interventions LANZA C - Mesenchimal stem cells reduce metallothionein up-regulation and oxidative stress in a rodent model for multiple sclerosis   - Expression of PARP-1 and oxidative stress-related enzymes in Sertoli cells during rat ontogenesis LANZANI C - Association between polymorphism of the cytoskeletal protein alpha-adducin andessential hypertension: role of the water channel, aquaporin 2 LANZANI G - Organic electronics allows the photo-electric excitation and inhibition of neuronal activity in primary neuronal cultures and acute retinal explants LANZANO R - Effects on aerobic fitness of an upper limb high intensity interval training LANZARINI E - Organic electronics allows the photo-electric excitation and inhibition of neuronal activity in primary neuronal cultures and acute retinal explants LANZILOTTO M - May the warning auditory-visual neurons help the monkey to play the piano?   - Neglect sindrome for aversive and pleasant stimuli in a macaque monkey with PEEF lesion LAPI D - Effects of propionyl-L-carnitine on microvascular changes during ischemia-reperfusion injury in hamster cheek pouch   - Apigenin and microvascular responses in rat pial microcirculation during hypoperfusion and reperfusion injury LAPI D - Pial microvascular responses after ischemia-reperfusion in rats: effects of Diosmin, a natural flavonoid   - Effects of ischemia-reperfusion injury on fatty liver microcirculation   - Rhythmic changes in diameter of rat pial arterioles under -chloralose anesthesia   - Pial arteriolar networks in obese zucker rats   - Long-term effects of trigeminal nerve stimulation on rat pial microcirculation: role of nitric oxide Lappin TRJ - PHD2: a major regulator of HIF-1alpha in oxygen homeostasis LAPSHINA KV - Exogenous heat shock protein 70 kDa affects sleep and thermoregulatory characteristics during endotoxaemia in pigeons   - Exogenous heat shock protein 70 affects sleep and thermoregulation after sleep deprivation in pigeons Lara JP - EFFECTS OF HYPOTHERMIA ON THE INHIBITION OF THE BARORECEPTOR RESPONSE EVOKED TO STIMULATION OF THE CAUDAL PERIFORNICAL HYPOTHALAMUS. A FREQUENCY DOMAIN APPROACH TO AUTONOMIC CARDIOVASCULAR CONTROL Lara JP - ROLE OF ANGIOTENSIN II IN A5 REGION MODULATION OF THE CARDIORESPIRATORY RESPONSE EVOKED FROM THE HYPOTHALAMIC DEFENCE AREA Laranjo S - EFFECTS OF HYPOTHERMIA ON THE INHIBITION OF THE BARORECEPTOR RESPONSE EVOKED TO STIMULATION OF THE CAUDAL PERIFORNICAL HYPOTHALAMUS. A FREQUENCY DOMAIN APPROACH TO AUTONOMIC CARDIOVASCULAR CONTROL Larbaoui Khelidja - STATUS OF MAGNESIUM IN DIABETIC SUBJECTS Lariviere E. - FAST, REVERSIBLE, CA2+ -INDEPENDENT VESICULARISATION OF THE ENDOPLASMIC RETICULUM LARIVIERE WR - Hippocamapal and behavioral effects of perinatal exposure to bisphenol-A on adult male rats on persistent pain. Modulation by estrogen and opioid Larkum M. - Martinotti interneurons control the generation of calcium spikes in layer 5 pyramidal dendrites in vivo Larque E - DEVELOPMENT OF PERIPHERAL SKIN TEMPERATURE CIRCADIAN RHYTHMICITY IN HUMAN Larrinaga G - DOWNREGULATION OF CB1 CANNABINOID RECEPTOR IN CLEAR CELL RENAL CELL CARCINOMA Larrode P - LIPID AND PROTEIN OXIDATIVE DAMAGE IN G93A MICE, A MODEL OF AMYOTROPHIC LATERAL SCLEROSIS Larsen *C. - Secretion of ATP by the exocrine glands of the colonic mucosa Larsen I - Nuclear medicine can select patients with heart failure to resynchronization therapy LARSEN AP - The HERG channel opener NS1643 shortens the QT in transgenic rabbits with long QT-syndrome 1 in vivo and shortens the APD90 ex vivo, but is associated with increased risk of arrhythmias Larsen EH - Cloning and functional characterization of mouse TMEM16F LARSEN EH - TMEM16F is associated with Cl- currents activated by Ca2+ LARSEN KB - mRNA expression and transport function of the proton-coupled amino acid transporter, PAT1, along the rat intestine Larsen L. E. - Long-term depression of pain perception in man affects peripheral receptive fields LARSEN LE - Heterotopic low-frequency stimulation induces nociceptive LTD within the same central receptive field in man LARSEN M - mRNA expression and transport function of the proton-coupled amino acid transporter, PAT1, along the rat intestine Larsen S - OBR PROTEIN EXPRESSION IS REDUCED IN HUMAN OBESE SKELETAL MUSCLE: A POTENTIAL MECHANISM OF LEPTIN RESISTANCE. Larsen T - -Nicotine amide adenine diphosphate - -NAD+- induces relaxation of the human myometrium smooth muscle. Possible role of small-conductance Ca2+-activated potassium channels in relaxation. LARSEN TS - High intensity interval training normalizes cardiac energetics and ventricular function in diet-induced obese mice LARSSON K - Inhibition of glucose induced insulin secretion by orexin-A LARSSON M - Small intestinal motility-secretion nteractions in health and disease LARSSON M - Synaptic AMPA receptor trafficking in pain hypersensitivity Lasaitiene D - Effect of the renin-angiotensin system (RAS) on kidney development and correlation with adult hypertension LASALA P - 3.5-diiodo-L-thyronine improves mitochondrial function in nonalcoholic steatosis through the stimulation of SIRT3 mitochondrial targets Lasarow Livia - The synaptic vesicle protein otoferlin is essential for efficient vesicle replenishment in inner hair cells Laser M - Heart-specific Integrin beta1 gene targeting abolishes compensatory cardiac hypertrophy due to altered expression of extracellular matrix components LASORSA D - Extracellular Ca2+-Sensing Receptor (CaSR) activates distinct intracellular calcium signalling in mouse cortical collecting duct cells   - Cyclin dependent kinases (Cdks) regulate AQP2 trafficking   - Renal aquaporin expression and osmotic water permeability is altered in mice fed a high fat diet LASORSA DR - Apical sorting of Aquaporin2: rafting towards the microvilli LASTEIN S - Antalarmin inhibits alarm reaction in crucian carp (Carassius carassius) Laszlo E. - EFFECTS OF IN VIVO RENAL ISCHEMIA/REPERFUSION IN HETEROZYGOUS PACAP DEFICIENT MICE Laszlo F. - CARDIO-PROTECTIVE ENZYME MODULATION BY RECREATIONAL PHYSICAL EXERCISE IN THE RAT Laszlo K. - THE ROLE OF INTAAMYGDALOID NEUROTENSIN IN CONDITIONED PLACE PREFERENCE TEST AND IN ELEVATED PLUS MAZE TEST Laszlo E. - MICE DEFICIENT IN PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE (PACAP) SHOW INCREASED SUSCEPTIBILITY TO IN VIVO RENAL ISCHEMIA/REPERFUSION INJURY Laszlo F. - EFFECTS OF OREXINS ON WATER INTAKE AND VASOPRESSIN SECRETION IN RAT Laszlo F. A. - EFFECTS OF OREXINS ON WATER INTAKE AND VASOPRESSIN SECRETION IN RAT Laszlo I. - COMPLEMENT C5A ANTAGONIST TREATMENT INFLUENCES THE GASTROINTESTINAL MICROCIRCULATORY COMPLICATIONS OF CARDIAC TAMPONADE Laszlo K. - EFFECTS OF NEUROTENSIN AND NEUROTENSIN RECEPTOR ANTAGONIST INJECTED INTO THE VENTRAL PALLIDUM IN CONDITIONED PLACE PREFERENCE TEST   - THE ROLE OF D2 DOPAMINE RECEPTORS OF THE VENTRAL PALLIDUM AND NUCLEUS ACCUMBENS IN PASSIVE AVOIDANCE LEARNING MECHANISMS   - EFFECTS OF INTRAAMYGDALOID MICROINJECTIONS OF RFRP-3 ON LIQUID FOOD INTAKE OF RATS Laszlo V. - IMMUNOREGULATORY ROLE OF HISTAMINE Laszy J. - THE ROLE OF TRPV1 RECEPTORS IN HIPPOCAMPUS-DEPENDENT LEARNING IN RODENT BEHAVIOURAL AND ELECTROPHYSIOLOGICAL MODELS Latal AT - Postnatal development of the neuronal glycine transporter 2 in the hypoglossal nucleus   - Modulation of glycinergic transmission in hypoglossal motoneurons by Zn2+ Latal T. - Miniature postsynaptic currents resulting from co-release of glycine and GABA to respiratory rhythmic glycinergic neurons in the mouse pre-Btzinger complex in situ LATORRE R - Characterization of KCNQ1 potassium channels expressed in Xenopus oocytes using non-stationary noise analysis Latorre E - Interleukin-10 reverses the oxidative damage induced by serotonin and TNF-alpha in human enterocyte-like Caco-2 cells   - Role of COX-2 from brain perivascular macrophages in the initiation of gastrointestinal (GI) motor disturbances and fever induced by LPS in sheep   - TLR3 and TLR4 activation and pro-inflammatory factors induce oxidative damage in enterocyte-like Caco-2 cells Latrache I. - ERM PROTEINS ARE INVOLVED IN VASCULAR SMOOTH MUSCLE CELL MIGRATION IN RESPONSE TO PDGF LATTANTE S - nAChRs in Amyotrophic Lateral Sclerosis LATTANZI D - Adult hippocampal neurogenesis: learning and swimming affect the time of synapse formation   - Motor reinnervation during muscular activity   - Exploration-addressed physical activity induces synaptogenesis anticipation onto adult-generated neurons in dentate gyrus   - Motor activity affects adult skeletal muscle re-innervation acting via Trk receptors   - Creatine protects and improves the morpho-functional differentiation of neuroblasts in spinal cord primary cultures LATTANZIO S - Tissue contribution to the mechanical features of diaphragmatic lymphatic vessels LATTANZIO S - Dynamic recruitment of diaphragmatic submesothelial lymphatics LATVANLEHTO A - Collagen XIII is a postsynaptic, multifunctional neuromuscular junction protein Latz S. - Ca2+-activated K+-Channels induce cardiac fate determination in various pluripotent cell types   - Characterization the Influence of Zoxazolamine on Cardiomyocyte Differentiation of Embryonic Stem Cells   - Analysis of EBIO induced Ca2+-signalling in layer-cultures of differentiating embryonic stem cells Latzenhofer B - Interaction between the selectivity filter and the cytoplasmic vestibule of the voltage-gated Na channel   - A cardiac cell environment induces expression of cardiac sodium channels in skeletal muscle cells Laubach M. - Ethnicity and use of medication in pregnant immigrated women Laube B - Modulation of glycinergic transmission in hypoglossal motoneurons by Zn2+ Lauber K - Mitochondria-independent death receptor mediated cytosolic acidification during apoptosis of T cells LAUDADIO S - Heart rate variability is modulated by neurons within the rostro ventromedial medulla   - Neurons within the rostro ventromedial medulla control cutaneous vasomotion LAUDANI L - Determinants of maximal instantaneous muscle power in young, middle-aged and older individuals LAUDANNA C - Rac1 activation improve retina ganglion cells survival and regeneration by ERK1/2 and Pak LAUFER J - Regulation of the glutamate transporter EAAT4 by PIKfyve Laufer J. - PIKfyve-dependent regulation of the Cl- channel ClC-2   - Regulation of the EAAT3 by PIKfyve   - SGK1 and PIKfyve in the regulation of the Ca2+ channel TRPV6 Laufer S. - Skepinone-L, a novel potent and highly selective inhibitor of p38 MAP kinase, effectively impairs platelet activation and thrombus formation   - Participation of leukotriene C4 in the regulation of suicidal erythrocyte death LAUG L - The human proton-coupled amino acid transporter PAT2: Mechanism and substrate specificity   - The human proton-coupled amino acid transporter hPAT1: Identification of a disulfide bridge essential for transport function   - The human proton-coupled amino acid transporter hPAT1: Transport of the antihyperglycemic drug -guanidinopropionic acid LAUGESEN J - The evaluation of coherence between many nephrons using laser speckle flowmetry Laugsch M - Tumour cell growth in response to erythropoietin and hypoxia Laugwitz K.-L. - In a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia dantrolene rescues arrhythmogenic RYR2 defect   - Modelling of long QT syndrome in patient-specific induced pluripotent stem cell-derived cardiomyocytes Laukeviciene A. - Endothelium moderates anaphylactic reaction of small isolated arteries in guinea pig Laukeviciene A - Influence of Perilla frutescens (L.) Britton extract on the contractility of rabbit myocardium   - Vasodilatory Effects of the Coumarins from Sweet Grass (Hierochloe odorata)   - Effect Bioelements on Contractility of Smooth Muscles of Coronary Arteries and Cardiomyocytes   - Anaphylaxis of small arteries: putative role of nitric oxide and prostanoids Lauks H - A conserved dimeric subunit stoichiometry of SLC26 multifunctional anion transporter Launikonis B.S. - Interleukin-1 interferes with sarcoplasmic Ca2+ release through the skeletal muscle ryanodine receptor: a new mechanism explaining muscle failure in critical illness myopathy Laura Martin María - 2-HYDROXY ARACHIDONIC ACID (2OAA), A NEW NON STEROIDEAL ANTI-INFLAMMATORY DRUG Laure Charles Anne - CYCLOSPORINE NORMALIZES OXIDATIVE STRESS AND PARTIALLY PROTECTS SKELETAL MUSCLE FROM ISCHEMIA-REPERFUSION INDUCED MITOCHONDRIAL DYSFUNCTION: AN INVOLVEMENT OF CYCLOPHILLIN D ? LAUREANTI F - Distribution of group II metabotropic glutamate receptors in the spinal cord of G93A-SOD1 mice, an animal model of amyotrophic lateral sclerosis   - Effect of dexamethasone and estradiol on proliferation and differentiation of rat bone marrow mesenchymal stem cells in cultures LAURI S - Presynaptic mechanisms of plasticity in the developing hippocampus   - High firing rate of neonatal hippocampal interneurons is due to attenuation of afterhyperpolarizing potassium currents by tonically active kainate receptors LAURI SE - Ongoing intrinsic synchronous activity is required for the functional maturation of CA3-CA1 glutamatergic synapses LAURILA M - Heat increment of feeding in the pigeon: substitution of cold thermogenesis or not? Laurindo FR - Protein disulfide isomerase is a central regulator of NADPH oxidase activity Laurinova K. - Clock gene expression during development LAURITZEN G - Roles of NHE1 and NBCn1 in pHi-regulation and survival in MCF-7 breast cancer cells expressing constitutively active ErbB2 receptors   - An N-terminally truncated ErbB2 receptor enhances migration of MCF-7 breast cancer cells: roles of the Na+/H+ exchanger NHE1 and the Na+,HCO3--cotransporter NBCN1   - The Na+,HCO3- cotransporter NBCn1 is upregulated in human breast tumors and by ErbB2: Mechanisms and implications Lauritzen G. - pH-regulatory ion transport in MCF-7 breast cancer cells: Effects of truncated ErbB2 receptor expression on transporter expression and activity, and role in resistance to cisplatin-induced death   - A N-terminally truncated ErbB2 receptor enhances migration of MCF-7 breast cancer cells: Roles of the Na+/H+ exchanger NHE1 and of cytoskeletal reorganization   - Novel roles of NHE1 in motility of serum-starved MCF7 breast cancer cells expressing truncated ErbB2 (?NErbB2) LAURITZEN M - Reduced GABAergic inhibition underlies cortical hyperexcitability in the wobbler mouse model of ALS LAURO C - Anomalous levels of Cl- transporters in human peritumoral cortical tissue make GABA excitatory   - Neuroprotective activity of fractalkine in cerebral ischemia   - Hippocampal neurons obtained from A1R-/- mice are not protected against Glu-induced excitotoxicity by CX3CL1 Lauro Clotilde - CROSS-TALK BETWEEN CHEMOKINES AND ADENOSINE IN NEUROPROTECTION AND NEUROMODULATION LAURSEN BE - Combretastatin-A4-phosphate, a novel vascular disrupting agent, indirectly enhances adrenergic neurotransmission. Lause P. - Myostatin gene deletion prevents glucocorticoid-induced muscle atrophy   - Inhibition of Atrogin-1 through the Akt-Foxo pathway by IGF-I does not prevent myotube atrophy caused by proinflammatory cytokines.   - Akt1 gene transfer by electroporation prevents skeletal muscle atrophy in glucocorticoid-treated rats. Lauterbach S. - Regulation of renal Epo production by HNF4α and HIF-2α - cause or coincidence?   - Relevancy of hypoxia-inducible factor (HIF)-1alpha on hematogenous metastasis of B16F10 melanoma cells after nitric oxide exposure Lavand'homme P. - CHIMERISATION OF ASTROGLIAL POPULATION IN THE LUMBAR SPINAL CORD AFTER MESENCHYMAL STEM CELLS TRANSPLANTATION PROLONGS SURVIVAL IN A RAT MODEL OF AMYOTROPHIC LATERAL SCLEROSIS LAVEDER P - Analysis of transcriptional profiles at single-fiber level in skeletal muscles LAVERTY G - Inhibition of chloride secretion by the sodium/hydrogen exchange inhibitor, EIPA, in permeabilized monolayers of chick renal proximal tubule cells. Lavinia Trancota Simona - AGE-RELATED CHANGES IN RESPIRATORY FUNCTION OF LIVER AND HEART RAT MITOCHONDRIA Lawo T - Cardiac contractility modulation by non-excitatory electrical currents might improve diastolic function in patients with chronic heart failure - a pilot study Lax P - CONTRIBUTION OF THE OOCYTE-FOLLICULAR CELL COUPLING TO THE MEMBRANE CAPACITANCE OF XENOPUS LAEVIS OOCYTES   - MELATONIN BLOCKS NICOTINIC CHANNELS IN CEREBELLAR GRANULE CELLS Lax P - FUNCTIONAL EXPRESSION OF NICOTINIC ACETYLCHOLINE RECEPTORS IN BOVINE RETINAL PIGMENT EPITHELIAL CELLS Layunta E - Interleukin-10 reverses the oxidative damage induced by serotonin and TNF-alpha in human enterocyte-like Caco-2 cells Lazar G - Study of the inflammatory cell response induced by bacterial LPS Lazar R - Young people development and motivation of the alcohol consumption Lazar Zs. - CLINICAL INVESTIGATION ON THE ROLE OF ADENOSINE TRIPHOSPHATE (ATP) IN AIRWAY DISEASES USING NON-INVASIVE METHODS LAZAREVIC D - Expression of vomeronasal receptors in mouse olfactory epithelium   - An old protein in unexpected places: alpha- and beta- globin expression in mesencephalic dopaminergic neurons and glial cells   - The transcriptional landscape of dopaminergic neurons Lazarov N - Expression of histamine receptors and effect of histamine in the rat carotid body chemoafferent pathway Lazarova Z. - The heart rate and blood pressure variabilities in children and adolescents with obesity Lazary J. - ASSOCIATION OF THE TNF-ALPHA +308 A/G POLYMORPHISM AND MAJOR DEPRESSIVE DISORDER Lazauskas R - Influence of Perilla frutescens (L.) Britton extract on the contractility of rabbit myocardium   - Anaphylaxis of small arteries: putative role of nitric oxide and prostanoids Lazo Y - RENAL PHENOTYPE IN AMPK ALPHA-2 KNOCKOUT MICE   - REGULATION OF RENAL Na-K-Cl COTRANSPORTER (NKCC2) BY NOVEL KINASES   - RENAL PHENOTYPE IN AMPK ALPHA-1 KNOCKOUT MICE Lazo Y - REGULATION OF SODIUM REABSORPTION IN HENLES LOOP AND DISTAL CONVOLUTED TUBULE; LINKS TO HYPERTENSION Lazou A. - The effect of diabetes mellitus on myocardial resistance to ischaemia/ reperfusion injury and PPAR expression in the rat heart LAZZER S - Combined hypoxia and bed rest for 10 days on skeletal muscle oxidative metabolism in vivo and ex vivo   - Effects of marked skeletal muscle hypertrophy in humans on oxidative function in vivo and in vitro Le Duc D. - Dynamics of cerebellar granule neurones response to oxygen and/or glucose deprivation in primary cultures Le Feuvre Yves - GABAb impairment in the dorsal horn of neuropathic rats: possible roles for associated proteins Le Henaff C. - Molecular mechanisms underlying kcnq1 voltage-dependency: the channel gate is locked closed by the S4-S5 linkers Le Huu S - Characterization of PHD3 function Le Mvel Jean Claude - CONTRASTING VENTILATORY ACTIONS OF CENTRALLY ADMINISTERED TACHYKININS, PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE AND VASOACTIVE INTESTINAL PEPTIDE IN TROUT le Noble F - A novel role for the neural guidance gene neuropilin-1 in programming cardiovascular disease Leal T. - CORRECTING EFFECT OF PHOSPHODIESTERASE 5 INHIBITORS ON CHLORIDE TRANSPORT IN CYSTIC FIBROSIS LEANZA G - Selective lesioning of Locus Coeruleus neurons impairs different aspects of spatial learning and memory in rats LEANZA C - 3.5-diiodo-L-thyronine improves mitochondrial function in nonalcoholic steatosis through the stimulation of SIRT3 mitochondrial targets LEANZA G - Cholinergic loss, amyloid deposition and cognitive dysfunction in a rat model. Prospects for restorative interventions Lebacq J. - Role of TRPV2 ion channel in the physiopathology of Duchenne muscular dystrophy   - CORRECTING EFFECT OF PHOSPHODIESTERASE 5 INHIBITORS ON CHLORIDE TRANSPORT IN CYSTIC FIBROSIS LEBECK J - AQP9 is not essential for ammonia uptake or urea release in the liver   - Regulation of the hepatic glycerol channel aquaporin-9 in starved rats is gender specific Lebecque P. - CORRECTING EFFECT OF PHOSPHODIESTERASE 5 INHIBITORS ON CHLORIDE TRANSPORT IN CYSTIC FIBROSIS LEBEDZEVA H - Selective lesioning of Locus Coeruleus neurons impairs different aspects of spatial learning and memory in rats Lebiecki J. - The tau mutation in mice and hamsters Leblanc N - Identification of TMEM16A as a molecular candidate for Ca2+ -activated Cl- channels in murine smooth muscle. Leboran V - TRANSFORMATION OF SENSORY INFORMATION INTO ACTION IN THE VENTRAL PREMOTOR CORTEX Leboran V - DECODING A DECISION PROCESS FROM THE VENTRAL PREMOTOR CORTEX NEURAL ACTIVITY Lebrun P. - EVIDENCE FOR KATP CHANNELS EXPRESSION IN THE EPIDIDYMIS FROM VARIOUS MAMMALIAN SPECIES   - ACROSOME DETECTION AND REACTION TO CALCIUM IONOPHORE CHALLENGE IN MOUSE SPERMATOZOA: METHODOLOGICAL CONSIDERATIONS   - KATP CHANNELS IN SPERMATOZOA: EXPRESSION IN DIFFERENT SPECIES AND INVOLVEMENT IN CALCIUM INFLUX   - NEW BENZOPYRAN DERIVATIVES ACTIVATING THE INSULIN-SECRETING CELLS KATP CHANNELS Lecca RM - Towards identification of renal genes regulated during metabolic acidosis   - Identification of renal genes regulated by metabolic acidosis LECCE B - Attentional cortical responses to enlarged faces are reduced in underweight subjects: an electroencephalographic study   - Attentional cortical responses to enlarged faces are increased in karate athletes: an electroencephalographic study   - Frontal attentional responses to food size are abnormal in obese subjects: an electroencephalographic study LECCHI M - Alterations in retinal ganglion cell activity in a model of diabetic retinopathy Leciejewski B. - Impaired CFTR function in cystic fibrosis airways can be recovered by mRNA transfection Lecomte M-J. - Conditional inactivation of the ChAT gene expression as a novel approach to investigate the physiology of cholinergic systems Lecorronc H. - MECHANISMS FOR PICROTOXININ AND PICROTIN BLOCKS OF ALPHA2 HOMOMERIC GLYCINE RECEPTORS Lederer W.J. - Arrhythmogenic Ca2+ waves in ventricular myocytes initiated by local activation of Ca2+ release channels Lederer WJ - Ca2+ sparks and Ca2+ leak in heart Ledo A - HIGHER OXYGEN FOR RESUSCITATION OF EXTREME PREMATURE FAVORS CHRONIC LUNG DISEASE (CLD)   - ARTERIAL OXYGEN SATURATION IN HEALTHY VERY PREMATURE INFANTS IS DELAYED AS COMPARED TO TERM NEWBORN INFANTS.   - HIGHER OXYGEN CONCENTRATIONS AT BIRTH ENHANCE LUNG INFLAMMATION AND CHRONIC LUNG DISEASE IN THE EXTREMELY PREMATURE INFANT   - HIGHER OXYGEN CONCENTRATIONS AT BIRTH ENHANCE LUNG INFLAMMATION AND CHRONIC LUNG DISEASE IN THE EXTREMELY PREMATURE INFANT Ledwig D - Calcitonin modulates the capsaicin induced changes of voltage activated calcium channel currents   - Modulation of capsaicin effects on voltage activated calcium channel currents by calcitonin Lee *M. - Pharmacological inhibition of the proline-rich tyrosine kinase PYK2 improves eNOS-dependent VEGF-induced angiogenesis Lee *W.-K. - ERK1/2-dependent bestrophin-3 expression prevents ER-stress-induced cell death of renal epithelial cells by reducing CHOP Lee CW - Noradrenergic neuron-specific gene transfer with nNOS decreases cardiac sympathetic neurotransmission Lee FS - PHD2: a major regulator of HIF-1alpha in oxygen homeostasis Lee SH - Stimulus intensity dependence of colour perception by heightened sensory perception (HSP®) trained children   - The effects of environmental luminance on colour perception in heightened sensory perception (HSP®) trained children Lee TS - The Cardiac Calcium Channel Regulates More than just Cardiac Contractility. Lee US - Stimulus intensity dependence of colour perception by heightened sensory perception (HSP®) trained children   - The effects of environmental luminance on colour perception in heightened sensory perception (HSP®) trained children Lee W - Evidence for KCNQ1 K+ channel expression in rat zymogen granule (ZG) membranes and involvement in cholecystokinin-induced pancreatic acinar secretion   - Cadmium (Cd) induced apoptosis is mediated by ceramide (Cer) formation and calpain activation in cultured kidney proximal tubule (PT) cells LEE YC - Sympathetic activation induces nitrergic vasodilation in the basilar arteries Lee A. - Ca2+ signals regulating hair cell transmitter release   - Interleukin-1 interferes with sarcoplasmic Ca2+ release through the skeletal muscle ryanodine receptor: a new mechanism explaining muscle failure in critical illness myopathy Lee B - Role of astrocytic glutamatergic signaling in Abeta oligomers toxicity Lee B. - M-PHASE KINASES PHOSPHORYLATE THE TYPE 1 INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR (IP3R1) IN MOUSE OOCYTES LEE HC - Sympathetic activation induces nitrergic vasodilation in the basilar arteries Lee I.O. - Left and Right atria of RacET mice follow a different cellular remodelling LEE MC - Characterizing the cortical activity related to the emergence of a conscious painful experience LEE MY - Expression analysis of microRNAs associated with vascular smooth muscle cell phenotypic modulation LEE TJF - Sympathetic activation induces nitrergic vasodilation in the basilar arteries Lee W.-K. - The lipocalin 2 receptor: A novel receptor mediating endocytosis of metal-protein complexes and cadmium-metallothionein toxicity in the kidney   - Cyclosporin A, but not FK506, induces osmotic lysis of pancreas zymogen granules, intra-acinar enzyme release, and lysosome instability by activating a K+ channel.   - Role of ferroportin-1 (FPN-1) in renal iron (Fe) handling   - Roles of oxidative stress, ceramide and calpains in heavy metal-induced cell death of cultured kidney proximal tubule cells LEE WK - Cadmium-induced DNA damage triggers G2/M arrest via chk1/2 and cdc2 in p53-deficient kidney proximal tubule cells   - Multidrug resistance P-glycoprotein/ABCB1/MDR1 protects against cadmium-induced apoptosis by reducing cellular ceramides Lee Fulton Benjamin - ACID-BASE BALANCE AND ARTIFICIAL CONTROLED VENTILATION IN WISTAR RATS: A CHRONOPHYSIOLOGICAL VIEW   - EFFECT OF REOXYGENATION ON HEART RATE VARIABILITY AFTER APNEIC EPISODE IN WISTAR RATS: A CHRONOBIOLOGICAL STUDY Leemans J. - Effect of fish oil supplementation in a model of feline asthma Leemans J. - INVOLVEMENT OF LIPID PEROXIDATION AND LIPOXYGENASE PATHWAY IN ALLERGEN-INDUCED INFLAMMATION IN CATS Leemans L. - Ethnicity and use of medication in pregnant immigrated women Lefebvre R.A. - PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR (PPAR) ACTIVATION ALLEVIATES POST-OPERA-TIVE ILEUS BY INHIBITION OF EGR-1 EXPRESSION AND ITS DOWNSTREAM TARGET GENES   - Characterization of intrinsic neurogenic excitatory and inhibitory motor responses in porcine distal colon   - INFLUENCE OF SELECTIVE PHOSPHODIESTERASE (PDE) SUBTYPE INHIBITORS ON THE INOTROPIC RESPONSE TO 5 HT4 RECEPTORS IN PORCINE LEFT ATRIUM Lefebvre RA. - 5-HT4 RECEPTOR ACTIVATION DOES NOT FACILITATE ACETYLCHOLINE OUTFLOW IN HIPPOCAMPAL BRAIN SLICES Lefevre *C. - hINaC and rBLINaC share electrophysiological characteristics Lefèvre C. - Single-channel properties of the human bile acid-sensitive ion channel (BASIC) Leffler A. - Evidence for functional expression of TRPV2 in rat DRG neurones Leffler A - A high-threshold heat-activated channel in rat DRG resembles TRPV2   - Local anaesthetic-evoked release of calcitonin gene- related peptide in mouse sciatic nerves involves TRPV1 LEFFLER A - The reactive metabolite methylglyoxal accumulating in diabetes activates primary sensory neurons LEFKIMMIATIS K - The role of Store-Operated Cyclic AMP Signalling (SOcAMPS) in cardiac physiology and pathology LEFLOCH R - Tumor adaptation to hypoxic and acidic stress Lefort S - Combined voltage and calcium imaging in vitro and in vivo reveals subthreshold and suprathreshold dynamics of mouse barrel cortex Legendre P. - MECHANISMS FOR PICROTOXININ AND PICROTIN BLOCKS OF ALPHA2 HOMOMERIC GLYCINE RECEPTORS   - MATERNAL INFLAMMATION AFFECTS EMBRYONIC MICROGLIA LEGNAME G - Role of the cellular form of the prion protein in central nervous system physiology Legrand A. - BLEOMYCIN AEROSOLIZATION: THE BEST ROUTE OF ADMINISTRATION FOR PULMONARY FIBROSIS MODEL IMPROVEMENT?   - DISTRIBUTION OF MECHANICAL ADVANTAGE AND RESPIRATORY ACTIVITY IN THE LEVATOR COSTAE MUSCLE   - MATCHING BETWEEN EMG ACTIVITY AND MECHANICAL ADVANTAGE IN THE EXTERNAL INTERCOSTAL MUSCLES OF THE RABBIT   - MECHANISMS UNDERLYING THE GRADIENT OF ELECTROMYOGRAPHIC ACTIVITY IN THE EXTERNAL INTERCOSTAL MUSCLE OF THE RABBIT   - CONTRIBUTION OF SEGMENTAL REFLEXES TO THE DISTRIBUTION OF EMG ACTIVITY IN THE EXTERNAL INTERCOSTAL MUSCLES Legros B. - THE EFFECT OF LEVETIRACETAM IN RAPID KINDLING LEH S - Alpha11 integrin affects osteopontin and Pdgfb expression in renal fibrosis   - Renal fibrosis in spontaneous hypertensive rats is associated with increased collagen fibril diameter and complex changes in growth factor expression LEHENKARI P - Cytokine secretion from adipocytes is regulated by vitamin D via the NF-B pathway   - Determination of cell viability of mesenchymal stem cells by analyzing mitochondrial function LEHIKOINEN E - Variation of corticosterone levels in barn swallows (Hirundo rustica) during pre-migratory fuelling LeHir M - Differential regulation of renal phosphate transporters by parathyroid hormone   - Abnormal differentiation of cells in the collecting duct of mice deficient for the AE1 Cl-/HCO3--exchanger LEHMAN J - The primary cilium as a cellular GPS for directional cell migration LEHMAN S - Orthophosphate and orthovanadate inhibit isometric force via two different pathways of the acto-myosin ATPase cycle Lehmann S - Ischaemic and inflammatory lung affection by extracorporeal circulation Lehmann S. - Adipose-derived stem cells, omega-3 fatty acids and angiogenesis   - Prevention of post-transplantation edema formation and pulmonary artery hypertension by systemic oxygenation in an ex vivo animal model Lehmann Horn Frank - OMEGA CURRENTS AND PARADOXICAL DEPOLARIZATION IN PERIODIC PARALYSIS Lehmann-Horn F - Motor endplate as a physiological target of the illicit drug ecstasy.   - Influence of intracellular cations on the effect of verapamil in mKv1.3 channels   - BK channel deficiency prevents low Cl-conductance myotonia, probably via reduced T-tubular K+ accumulation.   - Fast kinetics of single mechanotransducer channels in mammalian outer hair cells by AFM and patch clamp   - Does in vitro application of TRAM-34 arrest the human pancreatic cancer cell line MiaPaCa-2 during cell cycle progression or induce apoptosis?   - A computer model of the periodic paralysis in Andersen-Tawil-Syndrome (ATS).   - Intracellular cations affect the ability of verapamil to block currents through hKv1.3 channels   - Uncovering of sodium influx in the V388C mutant of the human voltage gated potassium channel Kv1.3   - Altered Closed-State Inactivation in Mutant Sodium Channel   - Influence of temperature on low Cl-conductance myotonia in vitro   - Uncovering slow deactivation of Kv1.3 L418C by suppression of inactivation   - ClC-1 chloride channel and myotonia in myotonic dystrophy type 2 (DM2)   - Active fascial contractility: Fascia is able to contract and relax in a smooth muscle like manner and thereby influence biomechanical behavior   - Interactions of N-terminal and C-terminal parts of the small conductance Ca2+ activated K+ channel, hSK3 change EBIO-sensitivity.   - Effects of osmolarity and [K+]o on the warm-up phenomenon in myotonic muscle   - How skeletal muscle influences the extracellular potassium concentration - a computer simulation study   - Characterization of the block of d-Tubocurarine on voltage-gated mKv1.3 potassium channels   - Characterization of the verapamil binding site in the human voltage-gated potassium channel Kv1.2   - Effect of Temperature on WT and R1448H Mutant Sodium Channels   - The voltage-dependent block of hKv1.3 H399T mutant channels by d-Tubocurarine LEHMANN-HORN F - Venous occlusion plethysmography for assessing cardiac output redistribution during exercise in the physiology lab   - Altered kinetics of Ca2+ transients in skeletal muscle fibres of a mouse expressing an N-terminal mutant huntingtin fragment Lehmann-Horn F - Pathogenesis of muscle channelopathies LEHMANN-HORN F - Insulin-mediated hyperpolarization of muscle fibers is caused by ATP-sensitive K+ channels   - Mechanism of K+-release from skeletal muscle caused by hyperosmotic expansion of the extracellular space   - Characterization of a novel Hypokalemic Periodic Paralysis mutation in DIS4 of the human skeletal muscle sodium channel Lehmann-Horn F. - Amphotericin B induced cation leak in skeletal muscle membranes and its implications for familial hypokalemic periodic paralysis   - Sunday, March 22, Hall 5Oral SessionSignaling in skeletal and smooth muscleChairpersons: K. Jurkat-Rott (Ulm)S. Wenzel (Giessen) Activation of the Na+/K+/2Cl--cotransporter in mammalian skeletal muscle   - Mutations C277Y and C277R cause dysfunction of human ClC-1 chloride channels resulting in myotonia congenita   - hNav1.4 gating model with temperature dependence obtained from a coherent set of experimental data   - Tuesday, March 24, Hall 3Oral SessionCI? channels and non-selective cation channelsChairpersons: C. Fahlke (Hannover)K. Jurkat-Rott (Ulm) Cellular Na+ overload and K+-dependent depolarization indicate a nonselective cation leak Lehmenkuhler A. - Rapidly recurring depolarizations in adult rat brainstem - a special case of spreading depolarization (SD)?   - Transient anoxic depolarization is unable to condition the brainstem of adult rats for spreading depression (SD)   - The proinflammatory cytokine TNF dose-dependently inhibits spreading depolarization (SD) in adult rat cortex Lehmenkühler A. - The proinflammatory cytokine TNFα inhibits cortical spreading depolarization (CSD) in adult rat cortex via neuronal TNF receptor 2 Lehmler J.-M. - Saturation properties of LTD- and LTP-like human pain plasticity Lehnart S - Ca2+ sparks and Ca2+ leak in heart Lehner W - Database Support of an Automated Multi-Channel Rheological Shear Stress Device -BTF-System Lehnert A - Immunoglobulins from patients with inflammatory cardiomyopathy can inhibit cardiac calcium currents   - Immunoglobulins from patients with inflammatory cardiomyopathy can inhibit cardiac calcium currents Lehotsky J. - Cerebral ischaemia/reperfusion injury in rats: impact to expression of novel secretory pathways Ca2+ pump (SPCA)   - Global ischaemic brain injury in rats: a time course of oxidative stress in plasma   - Neuroprotective influence of simvastatin to UPR reaction after global forebrain ischaemia/reperfusion LEHTI M - Circulating HDL levels modulate glucose and lipid homeostasis in trained mice LEHTI M - High fat diet, physical activity and intramyocellular triglyceride metabolism LEHTO VP - Effects of intravenously administered nanoparticles on arterial blood pressure and heart rate in rats LEHTOMAKI M - Do outbred ICR:CD1 mice form attentional sets in a bait digging set-shifting procedure? LEHTONEN S - Determination of cell viability of mesenchymal stem cells by analyzing mitochondrial function Le-Huu S. - HIF-1 affects etoposide-resistance and MDR-1 efflux activity   - Impact of prolyl-4-hydroxylase domain (PHD) enzyme 2 on cell motility and adhesion Lei M - Remodelling of Cardiac Pacemaker ICaL and Beta-adrenergic Responsiveness in Hypertension Following Cardiac nNOS Gene Transfer Lei Ming - Physiological consequences of age and sex for sinoatrial and atrioventricular function in murine Scn5a+/hearts LEI SHI - hypoxia decreases miR-223 and regulates IGF1R expression in mouse pulmonary vascular cells Leibetseder Valentin - Identification and tissue distribution of a novel alternatively spliced mRNA of human sulfonlyurea receptor 1 (SUR12) coding for a truncated KATP-channel opening peptide Leibrock *C. - Regulation of FGF23 expression by PI3 kinase sensitive GSK3 signaling Leibrock C. - Decisive role of excessive 1,25(OH)2D3 formation in the hypoglycemic effect of Klotho deficiency   - The Serum- & Glucocorticoid-inducible Kinase 1 (SGK1) influences platelet calcium signaling and function by transcriptional regulation of Orai1 expression in megakaryocytes   - Mineralocorticoid receptor sensitive soft tissue calcification and early death of Klotho-deficient mice   - SGK3 regulates Ca2+ entry and migration of dendritic cells   - Enhanced catecholamine release in mice expressing PKB/SGK-resistant GSK3   - Aldosterone dependent Tgf-beta activity in klotho-deficient mice   - Impaired platelet Ca2+ signaling and thrombus formation due to excessive 1,25 (OH)2 Vitamin D concentrations in Klotho-deficient mice   - Role of acid sphingomyelinase in the regulation of mast cells cell function   - Altered regulation of cytosolic Ca2+ concentration in dendritic cells from klotho hypomorphic mice Leibrock C.B. - PiT-1 regulates aldosterone-induced vascular osteoinductive signaling Leibrock F. - Protein kinase CK1 in the regulation of suicidal erythrocyte death LEIER G - Sildenafil enhances CFTR function through insertion and activation of the channel   - Antisense oligonucleotides as potent molecules for the long-term inhibition of ENaC expression Leier G. - Transfection of cystic fibrosis airway epithelial cells with wtCFTR-mRNA restores CFTR function   - Impaired CFTR function in cystic fibrosis airways can be recovered by mRNA transfection   - Establishing mRNA transfection procedures for functional CFTR correction LEINENWEBER A - Distinct sodium dependences of anion channels associated with glial and neuronal glutamate transporters Leineweber K. - TNF enhances the vasoconstrictor potential of serotonin and thromboxane through impairment of endothelial function Leipold E. - Scorpion -toxin Tz1 switches between excitatory and depressant modes in a voltage- and use-dependent manner   - A conserved splice variant of NaV1.8 voltage-gated sodium channel from human dorsal root ganglion neurons Leiprecht N. - Regulation of Na+-coupled glucose carrier SGLT1 by human papilloma viral protein HPV-18E6 Leipziger J - Mechanically provoked nucleotide release in distal colonic mucosa inhibits electrogenic Na+ transport   - Spontaneous nucleotide release from isolated perfused mouse medullary thick ascending limb   - Spontaneous [Ca2+]i oscillations in the perfused, intact nephron: a purinergic issue   - Role of Ca2+-activated BK and SK4 K+ channels in mouse colonic Cl-secretion   - Spontaneous [Ca2+ ]i-oscillations reflect nucleotide release from renal epithelia cells   - Aldosterone up-regulates KCa 1.1 (BK) channel- mediated colonic K+ secretion LEIPZIGER J - Autocrine purinergic signaling is essential for efficient macrophage chemotaxis Leipziger J - ATP inhibits Na+ absorption via basolateral P2 receptors in mouse medullary thick ascending limb (mTAL)   - AVP-stimulated nucleotide secretion in perfused mouse renal tubules LEIPZIGER J - Differential KCa1.1 channel mRNA expression in surface and crypt cells isolated from mouse distal colon Leipziger J. - Characterizing the pathway for nucleotide-release in renal epithelia   - A basolateral P2X receptor inhibits NaCl transport in mouse medullary thick ascending limb (mTAL)   - The thick ascending limb is the site of furosemide-induced urinary acidification   - E. coli α-haemolysin leads to ATP release and P2-dependent calcium influx in human erythrocytes   - The AVP-stimulated NaCl absorption in mouse medullary thick ascending limb is abolished by the V2 receptor antagonist satavaptan   - Impaired aldosterone responsiveness in corticosteroid binding gobulin deficient mice   - Adrenaline-induced colonic K+ secretion is conducted via KCa1.1 (BK) channel: implications of a regulated ZERO splice variant   - Hemolysis induced bya-hemolysin from Escherichia coli requires P2X and pannexin receptor activation   - The molecular compass for macrophage chemotaxis   - Secretion of ATP by the exocrine glands of the colonic mucosa   - Colonic K+ secretion: Gain of function in the KCNMB2 knockout mouse   - P2X receptor-mediated alkalization of mouse thick ascending limb Leiras R - DISTRIBUTION OF GLYCINE RECEPTORS IN THE CAT CENTRAL NERVOUS SYSTEM: AN AUTORADIOGRAPHIC STUDY USING [3H]STRYCHNINE. Leischner U - The transparent brain: Visualization of neuronal networks in the whole mouse brain Leischner U. - A new calcium signal component of mGluR1/TRPC3 mediated synaptic transmission Leisering *P. - Impact of the prolyl-4 hydroxylase domain enzyme 2 (PHD2) on tumor progression Leisering P. - Knockdown of prolyl-4-hydroxylase domain 2 inhibits tumor growth of human breast cancer MDA-MB-231 cells by affecting TGF-β1 processing   - Cellular changes induced by hypoxia in fibroblast and myoblasts Leisle L - N-linked glycans influence the expression of Acid- Sensing Ion Channel (ASIC) 1a and 1b on the cell surface Leiss V - Analysis of sodium and calcium channels in murine pancreatic islet cells Leist A. - Regulation of TRPM3 activity in pancreatic cells Leite-Almeida H - Influence of striatal dopamine D2 receptors on pain-related responses in an experimental model of peripheral neuropathy in the rat Leitges M - Transregulation of kinetics of calcium calmodulin kinase II (CaMKII) is implicated in anti-apoptotic control Leitner M. - Role of S1P1 receptor in nociceptor sensitization and inflammatory pain Leitner M. G. - Sphingosine-1-phosphate (S1P) pathway for heat hyperalgesia in C57Bl6J mice Leitner M.G. - Engineered voltage sensitive phosphatases reveal Ala126 and Thr167/Ile168 as determinants of the substrate specificity of PTEN   - The outer hair cell current Ik,n (KCNQ4) is modulated by the redox conditions   - A Ci-VSP/TPIP Chimera exhibiting voltage-dependent PI(4,5)P2/PI(3,4,5)P3-5-Phosphatase Activity Leitner MG - The outer hair cell potassium current IK,n requires PIP2 and is inhibited by poly-D-lysine and neomycin. Lejay Anne - CYCLOSPORINE NORMALIZES OXIDATIVE STRESS AND PARTIALLY PROTECTS SKELETAL MUSCLE FROM ISCHEMIA-REPERFUSION INDUCED MITOCHONDRIAL DYSFUNCTION: AN INVOLVEMENT OF CYCLOPHILLIN D ?   - SKELETAL MUSCLE MITOCHONDRIAL DYSFUNCTION DURING ISCHEMIA REPERFUSION: IMPLICATION OF OXIDATIVE STRESS AND PROTECTIVE EFFECTS OF ISCHEMIC PRE- AND POST-CONDITIONING Lekas R - Effect Bioelements on Contractility of Smooth Muscles of Coronary Arteries and Cardiomyocytes   - Thermography using for evaluation of myocardium function Leleux F. - KATP CHANNELS IN SPERMATOZOA: EXPRESSION IN DIFFERENT SPECIES AND INVOLVEMENT IN CALCIUM INFLUX   - ACROSOME DETECTION AND REACTION TO CALCIUM IONOPHORE CHALLENGE IN MOUSE SPERMATOZOA: METHODOLOGICAL CONSIDERATIONS LELIC D - Central neuroplastic changes of pain processing after LTD induction Lemaire K. - A reduction of glucose-induced bursting frequency in pancreatic islets correlates with decreased insulin release and impaired glucose tolerance in TRPM5-/- mice Lemaire S. - IS ACIDIC PH A NEW WEAPON TO FIGHT THE METHICILLIN-RESISTANT S. AUREUS (MRSA) SUPERBUG ? ROLE FOR PENICILLIN-BINDING PROTEIN 2A (PBP2a) LEMKENS P - Functional balance between endothelin-1 and calcitonin gene-related peptide in normotensive and hypertensive rats in vivo. Lemkens P. - ENDOTHELIN-1 AND CALCITONIN GENE-RELATED PEPTIDE CONTRIBUTE TO THE DEVELOPING HYPERTENSION IN YOUNG SHR Lemmens K. - EXPRESSION OF NEGATIVE REGULATORS OF HYPERTROPHY IN CONCENTRIC AND ECCENTRIC HYPERTROPHY OF RAT AND HUMAN LEFT VENTRICLES Lemmer Y. - SYSTEMIC ADMINISTRATION OF AG525E1, A SK CHANNEL BLOCKER, MODULATES MOTOR ACTIVITY IN RATS LEMONIER L - Ion transport proteins control pancreatic cancer cell behaviour LENA F - The right and left subthalamic nuclei equally contribute to arm response inhibition   - Cognitive effect of stop signals presence on preparation and execution of reaching movements in Parkinsons patients Lenard L - MAPPING OF LOCAL BRAIN ACTIVITY CHANGES IN THIRST MOTIVATED OPERANT SIGNAL DISCRIMINATION TASK OF RATS Lenard L. - EFFECTS OF NEUROTENSIN AND NEUROTENSIN RECEPTOR ANTAGONIST INJECTED INTO THE VENTRAL PALLIDUM IN CONDITIONED PLACE PREFERENCE TEST   - REWARD RELATED SINGLE-UNIT ACTIVITY CHANGES IN THE RAT MEDIAL PREFRONTAL CORTEX   - THE ROLE OF INTAAMYGDALOID NEUROTENSIN IN CONDITIONED PLACE PREFERENCE TEST AND IN ELEVATED PLUS MAZE TEST   - THE ROLE OF D2 DOPAMINE RECEPTORS OF THE VENTRAL PALLIDUM AND NUCLEUS ACCUMBENS IN PASSIVE AVOIDANCE LEARNING MECHANISMS   - AUDITORY SENSORY GATING MULTI UNIT AND LOCAL FIELD POTENTIAL ANALYSIS IN MEDIAL PREFRONTAL CORTEX IN FREELY MOVING RATS   - EFFECTS OF INTRAAMYGDALOID MICROINJECTIONS OF RFRP-3 ON LIQUID FOOD INTAKE OF RATS   - OPERANT CUED DISCRIMINATION TASK: EFFECTS OF NORADRENALINE LESION OF PRELIMBIC CORTEX   - COMPLEX FUNCTIONAL ATTRIBUTES OF FOREBRAIN GLUCOSE-MONITORING NEURONS IN THE MAINTENANCE OF HOMEOSTASIS Lenasi Helena - Effect of acute hyperglycemia on endothelium-dependent, NO-mediated vasodilatation in rat aorta   - Local regulation of human cutaneous microcirculation: impact of endothelium-dependent vasodilatation Lendeckel U. - Augmented endothelin-1 signaling in atrial myocardium from spontaneously hypertensive rats Lenders M. - Differential action of amiloride in human ex vivo endothelium Leng Gareth - NEUROTRANSMITTERS AND PEPTIDES: WHISPERED SECRETS AND PUBLIC ANNOUNCEMENTS Lenghel AR - Serum adiponectin and oxidative stress association in type 2 diabetes mellitus patients Leniger T - Differential antiepileptic effects of zonisamide on hippocampal CA-3 neurons. Lenk J. - Tracking and quantitative analyses of cell-junction dynamics in endothelial cells Lenkey Zs. - TROPONIN-I AND MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) LEVELS IN THE PERICARDIAL FLUID (PF) COULD BE EARLY INDICATORS OF MYOCARDIAL INJURY/ISCHEMIA AND PROINFLAMMATION LENNART BRODIN - Role of syndapin/PACSIN in synaptic vesicle recycling Lennartz K. - The effect of oxygen on placental connexins 43 and 46 and its contribution to preeclampsia LENTINI L - Adenosine is a modulator of the contractility of the duodenal longitudinal muscle in mice LENZEN E - Acute exercise-induced lipid- and peroxiredoxin- oxidation in erythrocytes of non-insulin-dependent type 2 diabetic men   - Hypoxia restores exercise-induced NOS-phosphorylation at Ser1177 in erythrocytes of non-insulin-dependent diabetic men Lenzen E. - Determination of lactate influx rates into erythrocytes after maximal exercise   - Exercise alters MCT1-protein expression and exercise-induced translocation in erythrocytes of men suffering from non-insulin dependent type II-diabetes   - Effects of sodium bicarbonate ingestion on pH and lactate distribution in different blood compartments after short term high intensity exercise   - Exercise-induced alterations of mitochondrial pathways in men suffering from non-insulin-dependent type 2 diabetes   - Endurance exercise improves peroxiredoxin expression in erythrocytes of men suffering from type 2 diabetes LENZI A - Short-term testosterone effects on neuromuscular excitability in hypogonadal males LENZI P - REM sleep entails arterial hypertension in hypocretin-ataxin3 narcoleptic mice   - Sleep-related and circadian control of arterial pressure are altered in leptin-deficient mice   - Leptin deficiency interferes with the physiological changes in cardiac vagal control among wake-sleep states   - Derangements of central autonomic and baroreflex control of heart period during the wake-sleep cycle in leptin-deficient obese mice   - Mathematical modelling provides proof of principle that phasic cardiovascular events in sleep result from integration of the arterial baroreflex and central autonomic commands   - The low-frequency fluctuations of blood pressure are not buffered by those of heart period during sleep: a pilot study with fixed-rate atrial pacing in rats LEO CH - Impairment of both nitric oxide and endothelium-derived hyperpolarizing factor in streptozotocin-induced diabetic small mesenteric artery.   - 7 day treatment with 3,4-dihydroxyflavonol prevents endothelial dysfunction in mesenteric arteries from streptozotocin-induced diabetic rats. LEONARDI G - Is there any benefit for experienced dancers in common upright stance? LEONARDI A - Technical learning affects physiological response of Nordic Walking at different slopes and speed. Leonardi I. - The role of the Leucine-Rich Repeat Kinase 2 (LRRK2) in development and severity of Inflammatory Bowel Disease (IBD) Leonardo-Mendonca R - Daily changes and regulation of melatonin receptors in rat liver   - Melatonin protects mitochondrial impairment in septic mice Leonardo-Mendoza R - BENEFICIAL EFFECTS OF TOPIC MELATONIN ADMINISTRATION AGAINST MITOCHONDRIAL DAMAGE DURING RADIOTHERAPY-INDUCED MUCOSITIS Leonarduzzi G - OXYSTEROL-MEDIATED SIGNALLING AS A PRIMARY MOLECULAR LINK BETWEEN HYPERCHOLESTEROLEMIA AND DISEASE LEONCINI S - Transcriptional and post-traslational modifications of scavenger receptor B1 (SRB1) in Rett syndrome. The role of oxidative stress   - Hypoxia affect the physiological behaviour of human neuroblastoma IMR-32 cells LEONE A - Is resting energy expenditure affected by TSH in euthyroid patients?   - Abdominal visceral adiposity measured by ultrasonography and risk of metabolic syndrome and its components: identification of predictive cut-off of risk LEONE L - Reduced D-serine levels in the nucleus accumbens of cocaine-treated rats hinder the induction of NMDA-dependent synaptic plasticity   - The dual role of Cav1 channels in neurogenesis and neurodegeneration   - Cyclic nucleotide-gated channels: new players in the regulation of neuronal and glial functions Leonhard-Marek S - Functional studies on Ca2+ -activated chloride secretion in the porcine colon   - 3-O-methyl-3H-glucose versus 3H-glucose as marker of intestinal glucose transport LEONI S - Proliferative non genomic effects of thyroid hormones are mediated by PI3kinase/Akt activation and ROS production   - Oleic acid but not fructose induces steatosis and insulin resistance in primary adult and fetal hepatocytes: preventive effect of 3,5-T2   - 3,5,3-Triiodothyronine (T3) stimulates cell growth through reactive oxygen species (ROS) and PI3K/Akt pathway   - Effect of Nickel salts on hepatocyte proliferation   - Nongenomic effects of thyroid hormones: An update Leontiev S - Processing of physiological function and vascularisation of an engineered heart tissue after implantation in rat heart in vivo   - New therapy for dilated cardiomyopathy based on engineered heart tissue (EHT) Leontyev S. - Electrophysiological changes in dilative cardiomyopathy during acidosis in rat heart Leon-Velarde F - Zinc supplementation leads to greater erythrocytosis and increased right ventricular hypertrophy (RVH) in rats exposed to hypoxia and related genes up-regulation. Lepage O - Dietary L-tryptophan suppresses aggression and stress responsiveness in juvenile rainbow trout (Oncorhynchus mykiss) Lepier A - Improved targeting of low affinity calcium indicators to the ER by overexpression of a carboxylesterase LEPPA E - Mechanisms of actions of neurosteroids in GABA-A receptor mouse model systems LEPPALUOTO J - Amount and intensity of physical activity and energy expenditure   - Impact exercise alters long-term bone turnover in a dose-dependent manner   - Time-course of exercise needed for bone changes in a 12-month intervention study   - Physical condition and objectively measured amounts and intensities of physical activity Lepran Á. - INVESTIGATION OF THE ROLE OF WATER-SOLUBLE CINNAMOMUM EXTRACT IN THE PREVENTION OF ATHEROSCLEROSIS Lepran I - EFFECTS OF FENOFIBRATE AFTER DIFFERENT FATTY ACID-RICH DIETS ON THE DEVELOPMENT OF HEART FAILURE IN RATS: DOBUTAMINE ECHOCARDIOGRAPHIC INVESTIGATION Lepran I. - INFLUENCE OF A PPAR ACTIVATOR AND DIFFERENT FAT-RICH DIETS ON ISCHEMIA-REPERFUSION INDUCED ARRHYTHMIAS IN RATS   - INVESTIGATION OF THE ROLE OF WATER-SOLUBLE CINNAMOMUM EXTRACT IN THE PREVENTION OF ATHEROSCLEROSIS Leprince P. - INTEREST OF A COMPARATIVE PROTEOMIC APPROACH TO UNRAVEL THE AETIOLOGY OF DOMS IN HUMANS Lerche H. - Nervous system Kv7 channelopathies Lerche H - Molecular analysis of a mutation in the S5-H5 linker of the KCNQ2 K+ channel causing neonatal convulsions   - Cu2+(1, 10 phenanthroline) 3 is an open channel blocker of the human skeletal muscle sodium channel   - The retigabine interaction site of KCNQ channels   - Subthreshold changes of voltage-dependent activation of the KV7.2 channel in neonatal epilepsy   - Functional characterization of a novel sequence variation in CACNA1H (Cav3.2) associated with childhood absence epilepsy   - Agonistic and potentiating effects of Phenobarbital on alpha1-A322D mutant GABAA receptor: a patch clamp analysis   - Coexpression of beta subunits refines the effects of a GEFS+ mutation on Nav1.1 channel gating Lerche H. - A conserved Threonine in the S1-S2 loop of Kv7.2/7.3 is important for voltage-dependent channel activation   - Developmental alterations in the expression of ion channels at axon initial segments associated with age-dependent seizures   - Depolymerization of cortical actin in chorea-acanthocytosis   - Chorein-sensitive polymerization of cortical actin and suicidal cell death in chorea-acanthocytosis Lerche Holger - KV7 CHANNELOPATHIES Leret ML - EFFECT OF EARLY STRESS ON BRAIN DEVELOPMENT Leret ML - GLUTAMIC DECARBOXYLASE ACTIVITY DETECTION IN A PARKINSONS RAT MODEL INDUCED BY HALOPERIDOL IN WISTAR MALE RATS, AND CAFFEINES EFFECTS ON BEHAVIOURAL AND BIOCHEMICAL PARAMETERS Lerma J - A ROLE FOR SNAP25 IN ENDOCYTOSIS OF KAINATE RECEPTORS AND SYNAPTIC PLASTICITY LERNMARK Å - Extrasynaptic-like GABA channels expressed in lymphocytes   - Lymphocytes express functional extrasynaptic-like GABA channels. Leroux A. - TWO-DIMENSIONAL, M-MODE AND PULSED WAVE DOPPLER ECHOCARDIOGRAPHIC REFERENCE VALUES IN HEALTHY ADULT SAANEN GOATS   - MYOCARDIAL DEPRESSION AS A COMPONENT OF ENDOTOXIC SHOCK IN HORSES: PRELIMINARY RESULTS FROM AN ECHOCARDIOGRAPHIC STUDY Leroy M. - Expression of porcine MX1 protein confers resistance to influenza A virus replication LESAGE F - TASK3 potassium channels are involved in the regulation of aldosterone secretion in mice Lesage F. - Monday, March 23, Hall 1Main SessionPhysiology and pathophysiology of K2P -channelsSymposium of the Working Group Heart and Circulation PhysiologyChairpersons: J. Daut (Marburg)R. Warth (Regensburg) Invalidation of TASK1 K+ channels disrupts adrenal gland zonation and mineralocorticoid homeostasis   - TASK3 potassium channels are involved in the regulation of aldosterone secretion in mice   - The role of Task3 K+ channels in development and function of the adrenal cortex   - Expression and localization of the TASK K+ channels in adrenal glands   - Deletion of TASK3 K+ channels leads to hyperaldosteronism in adrenal glands of neonatal mice   - Ca2+ signaling in adrenocortical slices   - The role of TASK3 potassium channel in the regulation of aldosterone secretion LESKELA TT - Interactions with calnexin and ER calcium pump SERCA2b regulate human delta opioid receptor maturation Lessmann V - Statin-induced nitric oxide production prevents C-reactive protein dependent disruption of the blood brain barrier   - Intracellular signalling cascades involved in activity-dependent synaptic secretion of neurotrophins LESSMANN V - Co-operation of N-cadherin and Neuroligin1 in the regulation of vesicle accumulation at nascent synapses Lestage P. - DESIGN, SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF NOVEL 7-SUBSTITUTED 3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE 1,1-DIOXIDES ACTING AS AMPA POTENTIATORS Letarte M - Role of endoglin in wound repair in adult endoglin heterozygous mice LETO G - Cytotoxic effects of a crude extract of extra virgin olive oil on Human HL60 cell lines sensitive and resistant with MDR phenotype   - Cytotoxic effects of polyphenols from wastewater of extra virgin olive oil on human HL60 and K562 cell lines Leuchtweis J. - The proinflammatory cytokine TNFα inhibits cortical spreading depolarization (CSD) in adult rat cortex via neuronal TNF receptor 2 Leuner *A. - Oxidized LDL-Cholesterol induces LOX-1 in human macrophages and endothelial dysfunction in aortas LEUNER A - Altered endothelial function in the thoracic aorta of LOX-1 overexpressing mice Leuner A. - Regulation of NADPH oxidase 4 in endothelian cells under hypoxia   - High-fat diet induces endothelial dysfunction in C57BL/6J mice   - Impaired vascular function in small resistance arteries of LOX-1 overexpressing mice on high-fat diet   - Phenotype of the adipose tissue in atherosclerotic LDLR-/- mice after high-fat diet feeding   - Expression pattern of scavenger receptor LOX-1 in metabolic active tissues after high-fat diet feeding   - NADPH oxidase 4 is upregulated under chronic hypoxia by a HIF-independent mechanism in endothelial cells Leung F. P. - Novel interaction between P450 eicosanoidsandendothelial nitric oxide in thecontrol arterial tone in mice LEUNG SWS - Long-term administration of rutin, a dietary flavonoid, increases the hypotensive actions of acetylcholine in spontaneously hypertensive rats. Levent Bas Ahmet - DEXAMETHASONE SUPRESSES KLEBSIELLA PNEUMONIAE INDUCED CYTOKINE PRODUCTION AND MIDKINE EXPRESSION IN RAT LUNGS LEVI R - Catestatin induces NO synthesis in endothelial cells by stimulating caveolae endocytosis and PI3K-dependent eNOS phosphorylation   - Catestatin-induced cardioprotection involves a PI3K-Akt-GSK3 pathway converging on mithocondrial membrane potential preservation Levitskaya NG - Study of ACTH (4–10) analogue Semax interaction with opioid system.   - Semax administration attenuates behavioral consequences of chronic restraint stress. Levitskaya NG - The heptapeptide Semax influence on analgesic and anxiolitic effects of morphine   - Influence of ACTH(4-10) analogue Semax administration on effects of neonatal stress caused by prolonged maternal deprivation in white rats.   - The ACTH(410) analogue SEMAX influence on stress-induced analgesia Levkau B. - Vasoconstrictor potential of aspirate from stented saphenous vein aorto-coronary bypass grafts and its pharmacological attenuation -insight into the no-reflow phenomenon-   - Vasomotor paralysis and potential downstream effects of paclitaxel from stents implanted for saphenous vein aorto-coronary bypass stenosis LEVONEN AL - Regulation of endothelial oxidative stress responses by microRNAs LEVY FO - Kinetics of myosin light chain phosphorylation in the heart Levy A. - TNFα is a central regulator of skeletal muscle resistance artery myogenic responsiveness in health and heart failure LEVY R - Safety and efficacy of genistein in osteopenic, postmenopausal women: a follow-up study Lewalter T - Cellular Cardiomyoplasty reduces Ventricular Vulnerability in the Infarcted Murine Heart Lewandrowski U. - Unravelling the interactome of guanylyl cyclase A, the receptor for atrial natriuretic peptide Lewczuk B. - Pinopsin in the pineal gland of the turkey   - The pineal concretions in the turkey as a result of collagen mediated calcification Lewen A - Properties of KCC2 mediated neuronal ammonium uptake Lewinska A - OXIDATIVE STRESS DURING MENSTRUAL CYCLE AND IN PREGNANCY Lewis and S. - Epinephrine stimulation of calcium-activated chloride channels in airway epithelia Leybaert L. - Influence of the membrane potential on Ca2+-dynamics in smooth muscle cells of intact small mesenteric arteries of the rat. Leybaert L. - GLIOTRANSMITTER RELEASE VIA CONNEXIN 43 HEMICHANNELS: ROLE OF CYTOPLASMIC CALCIUM CHANGES   - Connexin channels contribute to endothelial Ca2+ dynamics and alter blood-brain barrier function   - Cell death communication via connexin channels investigated in a C6 glioma cell model   - Calcium regulation of connexin-43 hemichannel-mediated ATP release in glial cells   - CONNEXIN HEMICHANNELS AND CALCIUM SIGNALLING BETWEEN BLOOD-BRAIN BARRIER ENDOTHELIAL CELLS   - CONNEXIN CHANNELS MEDIATE PROPAGATION OF APOPTOSIS IN A C6 GLIOMA CELL MODEL   - BETA-ODAP TOXICITY MAY BE RELATED TO A DISTURBANCE OF THE CELLULAR CA2+ HANDLING   - BETA-ODAP-TRIGGERED MITOCHONDRIAL CALCIUM OVERLOAD AS AN EARLY EVENT IN EXCITOTOXICITY   - MECHANISMS AND EFFECTS OF CALCIUM OSCILLATIONS/WAVES IN BLOOD BRAIN BARRIER ENDOTHELIAL CELLS   - INHIBITION OF CX43 HEMICHANNEL RESPONSES WITH HIGH [CA2+]I IS MEDIATED BY MECHANISMS DIFFERENT FROM CALCIUM ACTIVATION OF HEMICHANNEL RESPONSES   - Inhibition of connexin 43 hemichannel responses with high cytoplasmic calcium concentrations is mediated by mechanisms different from calcium activation of hemichannel responses   - Connexin 32, ATP release and X-linked charcot marie tooth disease   - CONNEXIN-43 HEMICHANNEL REGULATION BY INTRACELLULAR CALCIUM: INVOLVEMENT OF DIFFERENT SIGNALLING   - Hemichannels contribute to Ca2+ dynamics in smooth muscle cells in acutely isolated small mesenteric arteries   - Hemichannel involvement in Ca2+ dynamics and contractility of smooth muscle cells in acutely isolated small mesenteric arteries LEZNIK E - Role of amyloid-beta peptide in synaptic plasticity and memory   - Amyloid-beta peptide modulates hippocampal synaptic plasticity and memory Li *L. - Effects of the adiponectin paralogs CTRP 1-10 on glucose metabolism Li D - Noradrenergic neuron-specific gene transfer with nNOS decreases cardiac sympathetic neurotransmission   - Remodelling of Cardiac Pacemaker ICaL and Beta-adrenergic Responsiveness in Hypertension Following Cardiac nNOS Gene Transfer Li FYL - VASCULAR DYSFUNCTION IN AGING: PROTECTIVE ROLE OF PHYTOESTROGENS Li H - MIF: A brake for the neuronal actions of angiotensin Li L - Physical activity increases mitochondrial biogenesis and respiration independent of insulin resistance in left ventricular myocardium of obese mice LI R - Vasodilation by perivascular adipose tissue: unaltered in SHR Li Wei - Structure and function of serpins in blood coagulation system Li C - LEUKIN experiment on board the International Space Station demonstrated that microgravity inhibits the Rel/NFkB Pathway and Transcription of Immediate Early Genes in T cell activation Li Geng-Lin - Quantal size and multivesicular exocytosis at the hair-cell synapse: Paired recordings with membrane capacitance measurements LI J - The electroneutral Na+HCO3-cotransporter NBCn1 plays an essential role in duodenal acid/base balance and colonic mucus layer build-up in anesthetized mice   - Membrane expression of deltaF508 mutant increases epithelial HCO3-secretion via functional Cl-/HCO3-exchanger(s)   - Loss of anion exchanger Slc26a3 (DRA) expression results in severely decreased murine colonic HCO3-secretion, low surface pH, disturbed mucus barrier, signs of colonic mucosal inflammation, and increased susceptibility to DSS-induced injury Li J - Differential involvement of Slc26a3 (DRA), CFTR, and other HCO3- transporters in murine ileal, proximal and distal colonic HCO3- secretion Li J. - Membrane expression of F508del mutant increases epithelial HCO3- secretion via functional Cl-/HCO3-exchanger(s)   - Evaluation of Current Components in murine CD117(pos) AT2R(pos) Bone Marrow Stem Cells LI JP - Chemotactic Gradient Induces Directional Intravascular Crawling of Leukocytes Li L. - Effects of a chronic deficiency in nitric oxide on the structural and functional remodeling of the left and right ventricle   - Protective effects of adiponectin and the paralogs CTRP 1-10 in the heart   - Mitochondrial biogenesis and PGC-1alpha deacetylation by physical activity: Intact leptin signaling is required LI M - Zebrafish larval muscle physiology - a novel approach for analysis of sarcomeric protein function   - Myosin binding protein C (MyBPC) plays a role in contraction of zebrafish skeletal muscle LI R - Vasodilation by perivascular fat: modulation by steroids Li S - Role of histaminergic system in dopamine-induced arousal Li S. - Waking action of ursodeoxycholic acid (UDCA) depends on histamine and GABAA receptor block Li Tongju - The hypertonicity-induced cation channel (HICC) in human hepatocytes: Role in proliferation vs. apoptosis and molecular characterization LI VOLSI G - Noradrenergic modulation of neuronal activity in cerebellar deep nuclei of the rat LI W - Ciliary Function of the Drosophila TRPP2 Homologue Li Y. - Pre- and postsynaptic functional changes at glutamatergic and GABAergic synapses in a focal lesion model in rat visual cortex LI VOLSI G - 1 adrenergic modulation of NMDA-evoked neuronal responses in the vestibular complex   - From head-related vestibular signals to body-related vestibulospinal reflexes: the role of medullary reticular formation   - Forelimb afferents may tune the responses of cerebellar cortex and vestibular nuclear neurons to labyrinthine stimulation   - Effect of dexamethasone and estradiol on proliferation and differentiation of rat bone marrow mesenchymal stem cells in cultures   - Noradrenergic modulation of N-methyl-D-aspartate-evoked neuronal responses mediated by 1-adrenoceptor in vestibular secondary neurons LIANG CF - Loss-of-function in Toll-like receptor 4 (TLR4) alleviates metabolic syndrome and endothelial dysfunction in genetically obese mice. LIANG B - Reduction in cardiac Kir3.4 channel expression causes congenital long QT syndrome - A functional role of GIRK currents in ventricular repolarization LIANG L - Protective potential role of CGRP in the onset of murine hypertension. LIANG M - Temporal expectancy and not refractoriness explains the repetition suppression of laser-evoked potentials (LEPs)   - Determinants of laser-evoked EEG responses: effect of predictable and unpredictable changes in stimulus location Liantonio A - Biophysics and molecular pharmacology of chloride transporting CLC proteins Liao Y - Coexpression of beta subunits refines the effects of a GEFS+ mutation on Nav1.1 channel gating   - Increased brain infarction after transient focal cerebral ischemia in BK channel-deficient mice Liardet M.P. - Blood oxygen binding in sheep – a comparative study. LIASHKOVICH I - Dexamethasone induces nuclear envelope barrier leakiness   - Novel method of controlled and inducible AFM tip functionalisation for investigation of orientation-specific interactions between large biomolecule complexes Liashkovich I. - Shedding light onto the enigmatic nuclear delivery process of herpes simplex virus genome   - Caspases 3 and 9 pave the way for apoptosis through breakdown of the nuclear barrier   - Structural arrangement of the nuclear pore permeability barrier   - How does the Herpes simplex virus genome overcome the tight nuclear barrier?   - Endothelial cell stiffness explored by a combination of fluorescence and atomic force microscopy   - Delivery of herpes simplex virus type 1 genome through the nuclear pore complex   - Controlled breakdown of the nuclear pore permeability barrier   - Interaction of Herpes Simplex Virus with the Nuclear Pore Complex   - Nuclear Permeability Barrier - What is the Structural and Molecular Basis? Libran-Perez M - Arginine vasotocin is a potent anorexigenic factor in the trout   - Glucose concentration influences ACTH-stimulated cortisol release by head kidney of rainbow trout Libran-Perez M. - A metabolic fatty acid sensing mechanism is present in central and peripheral tissues of rainbow trout LICATA F - Noradrenergic modulation of neuronal activity in cerebellar deep nuclei of the rat   - 1 adrenergic modulation of NMDA-evoked neuronal responses in the vestibular complex   - Noradrenergic modulation of N-methyl-D-aspartate-evoked neuronal responses mediated by 1-adrenoceptor in vestibular secondary neurons LICATA G - Effects of genistein, a soy-derived isoflavone, in postmenopausal women with metabolic syndrome LICCIARDI A - Adaptations to long-term apnoea training   - Plasma leptin and VEGF levels after maximal exercise at high altitude (5050 m)   - Bronchial epithelial thickness is incresed in small airways of MDX mice at rest and after training   - Recovery of damaged skeletal muscle in mdx mice by low-intensity endurance exercise Licht AH - The AP-1 subunit Junb controls the contractile capacity of vascular smooth muscle cells Lichtman JW - Brainbow: Combinatorial expression of fluorescent proteins to visualize neuronal circuits Lidington D - Caveolin-1 and Kv channels modulate the myogenic response LIDINGTON D - Serine 225 phosphorylation governs the localization and function of sphingosine kinase 1 in resistance arteries   - Tumor necrosis factor is involved in the myogenic response of resistance arteries Lidington D. - Targeting TNFα/S1P signaling restores microvascular reactivity and normal cerebral blood flow following experimental subarachnoid hemorrhage Liebau S - SK3 channels are involved in triggering the outgrowth of filopodia like structures in neural progenitor cells Liebau S. - Analysis of EBIO induced Ca2+-signalling in layer-cultures of differentiating embryonic stem cells   - Ca2+-activated K+-Channels induce cardiac fate determination in various pluripotent cell types LIEBERER E - Biophysical consequences of KCNJ10 mutations causing EAST syndrome   - EAST syndrome: Mutations in the KCNJ10 potassium channel gene cause epilepsy, ataxia, sensorineural deafness, and salt-wasting tubulopathy Lieberer E. - KCNJ10 potassium channels in the mouse distal nephron Lieberz R. - Cytochrome P4502S1 a novel monocyte/macrophage fatty acid epoxygenase Liebig G - Amyloid induced suicidal erythrocyte death Liebler S. - Deregulated angiogenesis as the cause of cerebral cavernous malformations   - Notch signalling is essential to maintain vascular integrity Liebner S. - sEH-deficiency attenuates neointima formation in the femoral artery cuff model of hyperlipidemic mice LIEDKE W - The cation channel TRPV2 is upregulated in skeletal muscle of TRPV4 deficient mice and may contribute to background Ca2+ influx. Liedtke W. - TRPV4 channels in mouse skeletal muscle: their role for Ca2+ homeostasis, muscle fatigue and motor function Liegeois J.-F. - LONG-TERM EFFECTS OF JL13, A CLOZAPINE-LIKE ANTIPSYCHOTIC, ON RAT DOPAMINE RECEPTORS   - COMPARATIVE EFFECTS OF RECENTLY DEVELOPED ANTIPSYCHOTICS AND JL13 IN A PASSIVE AVOIDANCE TASK IN MICE Liegeois J.-F. - SYSTEMIC INJECTION OF A SK BLOCKER INCREASES BURSTING OF MIDBRAIN DOPAMINE NEURONS IN AWAKE RATS   - Combined experimental and computational approaches to study the action of blockers of small conductance calcium-activated potassium (SK) channels   - Combined experimental and computational approaches to study the action of blockers of small conductance calcium-activated potassium (SK) channels   - SYSTEMIC ADMINISTRATION OF AG525E1, A SK CHANNEL BLOCKER, MODULATES MOTOR ACTIVITY IN RATS   - BLOCK OF SK CHANNELS BY THE SIGMA AGONIST 1,3-DI-O-TOLYL-GUANIDINE: EVIDENCE FOR A NOVEL SITE OF ACTION FOR SK BLOCKERS Liegeois J-F. - SK CHANNEL BLOCKADE PROMOTES BURSTING IN VIVO IN DORSAL RAPHE SEROTONERGIC NEURONS Liehn EA - Essential role of the growth-regulated oncogene alpha/CXCR2 axis in homing of human endothelial progenitor cells Liem D. - Chronic -adrenergic agonist induced regulation of proteasome function in cardiac remodeling   - Regulation and role of proteasome subpopulations in -adrenergic agonist-induced cardiac remodeling LIERE P - Neurosteroids in neuronal damage and repair Lies *B. - Gastrointestinal nitrergic relaxation by smooth muscle and non-smooth muscle cells Lies B. - Fertility in male mice lacking NO-sensitive guanylyl cyclase   - Two independent cGMP-mediated pathways mediate nitrergic relaxation in ICC and SMC: Studies in mice lacking NO-sensitive guanylyl cyclase   - Achalasia in mice lacking NO-sensitive guanylyl cyclase   - NO - guanylyl cyclase in murine endothelial cells? LIETTU A - Functional connectivity alterations in seasonal affective disorder overlap with extra-visual light therapy effects LIFTON R - Functional characterization of a novel mutation in the -subunit of the epithelial sodium channel (ENaC) found in Liddle's syndrome Ligeti L. - Diabetic cardiomyopathy is associated with impaired intracellular calcium (Ca2+i) release and sequestration Ligeti L - Computational analysis of disturbed calcium handling in the diabetic heart   - Calcium handling in the diabetic heart Lightman S.L. - Pulsatility as a key aspect of HPA regulation Ligia Rusu - NEUROMUSCULAR INVESTIGATIONS IN MULTIPLE SCLEROSIS LIGNANI G - Role of Synaptic Vesicle trafficking in excitation/inhibition balance LIGUORI E - Effects of ischemia-reperfusion injury on fatty liver microcirculation Likavcanova K - Metabolic changes in thalamus after spinal cord injury. Lilienthal Hellmuth - Effects of environmental pollutants on auditory function in adult rats after exposure during development Lilius E-M - BACTERIAL AND VIRAL INFECTIONS ACTIVATE NEUTROPHILS DIFFERENTLY LILJA M - Biochemical characterization and comparison of N-terminal Gly16Arg variants of the 2-adrenergic receptor LILLE M - Effects of modified protein structure on intestinal peptide release and satiety in healthy young men LILLYWHITE HB - The influence of gravity on heart position and blood pressure regulation LIM   - Excitation and contraction of cardiac muscle and coronary arteries of normal and brain dead pigs Lima CF - Salvia fruticosa tea reduces the expression of SGLT1 in rat intestinal epithelium Lima E - INFLAMMATORY RESPONSES INDUCED BY ECCENTRIC EXERCISE IN PERIPHERAL BLOOD MONONUCLEAR CELLS IN THE ELDERLY Lima E - ECCENTRIC EXERCISE INDUCES HIF-1 ACTIVATION AND iNOS EXPRESSION IN RAT SKELETAL MUSCLE Lima I S. - Vagalnitric oxide axis regulates postprandial glucose excursions. Lima Rodriguez L - Interleukin-6 deficiency modulates the hypothalamic expression of energy balance regulating peptides during pregnancy in mice Lima-Flores A - OXIDATIVE DAMAGE IN YOUNG PEOPLE BY ALCOHOLIC BEVERAGES CONSUMPTION LIMATOLA C - Neuroprotective activity of fractalkine in cerebral ischemia Limatola Cristina - CROSS-TALK BETWEEN CHEMOKINES AND ADENOSINE IN NEUROPROTECTION AND NEUROMODULATION LIMATOLA C - Glioma cells alter neuronal chloride equilibrium through extracellular glutamate release   - CX3CL1-induced modulation at CA1 synapses reveals multiple mechanisms of EPSC modulation involving adenosine receptor subtypes   - Hippocampal neurons obtained from A1R-/- mice are not protected against Glu-induced excitotoxicity by CX3CL1   - Desensitization of GABAA receptors expressed in glial cell membranes of mouse neocortex using the xenopus oocyte microtransplantation expression system is reduced compared to that developing in nerve cells   - Differential effects of Zn2+ and Cu2+ on neuronal and glial GABAA receptors, expressed by Xenopus oocytes microtransplanted with mouse neocortex membranes   - Modulation of GABAA-mediated currents by GABAB receptors in temporal pyramidal neurons in control or epileptic tissue   - CX3CL1 modulates stretch-activated channels in mouse microglial cells Limatola C - Attentional cortical responses to enlarged faces are reduced in underweight subjects: an electroencephalographic study LIMATOLA C - nAChRs in Amyotrophic Lateral Sclerosis   - CXCL12-induced glioblastoma cell migration requires intermediate-conductance calcium-activated K channel activity   - Effects of CX3CL1-CX3CR1 signaling on the functional properties of microglial cells in hippocampal acute slices from developing mice   - PKA and A2A adenosine receptor activation functionally modulate human nicotinic 34 receptors   - Anomalous levels of Cl- transporters in human peritumoral cortical tissue make GABA excitatory   - CXCL16 neuroprotection upon glutamate excitotoxicity is mediated by adenosine Limatola Cristina - CXCL16 ORCHESTRATES ADENOSINE A3 RECEPTOR AND MCP-1/CCL2 ACTIVITY TO PROTECT NEURONS FROM EXCITOTOXIC CELL DEATH IN THE CNS Limberg S - Thymosin b 4 activates calcium dependent potassium current in human monocytes   - Inside-out patch-clamp measurements reveal that diacylglcerol directs regulates TASK-3 channels Limberg M. - Electrophysiological characterization of novel SCN5A mutations involved in LQT syndrome Limberg S. - TASK-1 channels in cardiac muscle cells of murine and human heart Limet R. - COMPARATIVE EFFECTS ON LV PERFORMANCE, ARTERIAL HEMODYNAMICS AND VENTRICULO-ARTERIAL COUPLING OF TWO PORCINE MODELS OF CORONARY ARTERY OCCLUSION LIMONTA E - Effect of respiratory muscle training on maximum aerobic power in normoxia and hypoxia   - Fatigue and cooling alter skeletal muscle electromechanical characteristics during isometric contractions LIMONTA P - Role of type 1 GnRH receptor in mediating the anti-proliferative effect of GnRH-II in human prostate cancer cells   - Role of ER on the migratory behaviour of prostate cancer cells Lin BJ - Spontaneous and odor-modulated calcium activities in the olfactory bulb and their correlation with electrical activities   - In-situ background estimation in quantitative fluorescence imaging Lin H - Expression and activity of SNAT2 in isolated rat cardiomyocytes.   - Effect of cysteine on the activity of antioxidant enzymes in isolated rat cardiomyocytes   - Cardioprotection with hyperkalaemia but not with ischaemic preconditioning is associated with inhibition of mitochondrial permeability transition pore Lin Fang-Chin - -Adrenoceptor stimulation potentiates insulin-stimulated PKB phosphorylation in rat cardiomyocytes via cAMP and PKA Lin Hua - Postnatal changes in the cardiomyocyte- contractility and calcium transients LIN H-Y - Thyroid hormone inhibition of IGF-1-mediated glucose uptake in myoblasts L-6 through interaction with the alphaVbeta3 integrin Lin J. - GUCY2C at the intersection of obesity and colorectal cancer Lin J.S. - Waking action of ursodeoxycholic acid (UDCA) depends on histamine and GABAA receptor block Lin J.-S. - Excitation of histaminergic tuberomamillary neurons by thyrotropin-releasing hormone Lin JS - Role of histaminergic system in dopamine-induced arousal Lin Y. - Sgk1 sensitivity of Na+/H+ exchanger activity and cardiac remodeling following pressure overload   - Cardiomyocyte-specific Prolyl-4-hydroxylase Domain 2 knock out protects from acute myocardial ischaemic injury but is deleterious with aging   - Detrimental consequences of chronic cardiac overexpression of HIF-1 for heart function Linares V - PRO-OXIDANT EFFECTS IN THE BRAIN OF RATS EXPOSED TO BDE-99   - IMPAIRMENT IN THE REPRODUCTIVE SYSTEM OF MALE RATS INDUCED BY BDE-99 EXPOSURE Linares-Clemente P - VISUALIZATION OF SYNAPTIC VESICLE CYCLE ALTERATIONS AT THE NERVE TERMINALS OF SYNAPTOPHLUORIN TRANSGENIC MICE LACKING CYSTEINE STRING PROTEIN-ALPHA (CSP-ALPHA).   - FUNCTIONAL MAINTENANCE OF NERVE TERMINALS IN THE ABSENCE OF CYSTEINE STRING PROTEIN-ALPHA (CSP-ALPHA). Linares-Clemente P - CSP-ALPHA IS REQUIRED TO PREFERENTIALLY PREVENT NEURODEGENERATION OF GABAERGIC SYNAPSES IN CULTURED HIPPOCAMPAL NEURONS LINARI M - Orthophosphate and orthovanadate inhibit isometric force via two different pathways of the acto-myosin ATPase cycle LINARI M - X-ray diffraction estimate of the relative contributions of subfragment-1 and -2 of the myosin molecule to the compliance of muscle cross-bridges   - Structural changes in the myosin motors during activation and force generation of muscle   - N-benzyl-p-toluene sulphonamide (BTS) used to test force generation kinetics of myosin motors in muscle   - The effect of phosphate on the mechanics and energetics of the isometric contraction of skeletal muscle   - Relative contribution of attached and detached myosin heads to the X-ray pattern determined in muscle fibers contracting at different sarcomere lengths   - Structural changes in myosin motors and filaments during unloaded shortening and isometric force redevelopment after shortening   - X-ray diffraction study of the effect of temperature on the structure of mammalian muscle at rest and during isometric contraction   - Structural changes in muscle during relaxation   - Cholesterol biosynthetic pathway inhibition is related to functional changes of fast skeletal muscle   - A low angle X-ray diffraction study of the relaxed and activated states of skinned fibres of rabbit psoas muscle   - The effect of inorganic phosphate on transient and steady state responses of demembranated fibres from skeletal muscle LIND O - Colour vision limits in dim light Lindblad-Toh K - The dog as a genetic model of human cardiovascular disease LINDBOM L - Cross-talk in innate immunity: Neutrophils enhance bacterial phagocytosis in macrophages   - Evidence for neutrophil interactions with atherosclerotic endothelium in vivo Linde Sofia - Glial fibrillary acidic protein and vimentin are negative regulators of the neurogenic niche Lindecke A - Cardiac function and gene expression pattern in myoglobin knockout mice under isoproterenol induced stress Lindecke A. - Accelerated atherosclerosis inapolipoprotein E/ecto-5nucleotidase (CD73) double-deficient mice Lindemann *O. - The role of TRPC6 in chemotactic signaling of murine neutrophils   - TRPC channels in neutrophil recruitment Lindemann O - The role of TRPC1 and TRPC6 channels in chemotaxing neutrophils LINDEMANN O - System dynamics of directed cell migration   - Is the transient receptor potential canonical 1 (TRPC1) channel a downstream target of mechanosensitive signalling cascades? Lindemann O. - The role of the Ca2+ channels TRPC1 and TRPC6 in neutrophil migration   - Monday, March 23, Hall 4Oral SessionTRP channelsChairpersons: A. Cavali (Homburg/Saar)A. Schwab (Mnster) TRPC1 channels guide migrating cells in chemokine gradients   - Pancreatic stellate cells can migrate and chemotax   - TRPC channels 1 and 6 are required for efficient transendothelial migration of neutrophil granulocytes   - The role of TRPC1 and TRPC6 channels in the regulation of intravascular migration of neutrophils under shear stress   - Mathematical model analysis of the influence of TRPC1 channels on directed migration of murine neutrophils   - Role of TRPC1 in murine granulocyte stimulation Lindemann Otto - Ion channels keep mobile cell on the go Lindemann S. - SDF-1 mediated platelet migration is regulated by the PI3K downstream effector SGK1   - SGK1 and ion channels in the regulation of platelet migration LINDEN A-M - Do outbred ICR:CD1 mice form attentional sets in a bait digging set-shifting procedure? LINDEN AM - Mechanisms of actions of neurosteroids in GABA-A receptor mouse model systems LINDENBERG KS - Altered kinetics of Ca2+ transients in skeletal muscle fibres of a mouse expressing an N-terminal mutant huntingtin fragment Linderholm Bim - IN VITRO AND IN VIVO CHARACTERISTICS OF CYCLED LUNG SURFACTANT ARE PRESERVED BY FIBRINOGEN Linders J.T.M. - Molecular Determinants of IKs channel sensitivity to JNJ-303 LINDFORS C - Kei Tatemoto's and Viktor Mutt's neuropeptides: Focus on NPY and anorexia LINDHOLM M - Evaluation of vascular effects of oats in mice LINDHOLM D - Neuroprotective action of resveratrol against oxidative stress in the MPTP mouse model of Parkinson's disease   - Activation of PGC-1 protect dopaminergic neurons in the MPTP mouse model of Parkinson's disease Lindholm Harri - NORDIC WALKING DECREASED CIRCULATING CHEMERIN AND LEPTIN CONCENTRATIONS IN PREDIABETIC MIDDLE-AGED MEN Lindner *M. - A toolset to dissect Gq-protein coupled receptor signaling provides new insights into TASK-channel regulation Lindner R - Upregulation of HERG channels by the serum and glucocorticoid inducible kinase isoform SGK3 Lindner M. - Analysis of Phospholipase C dependent inhibition of TASK channels   - Inhibition of the potassium channel TASK-1 in rat cardiac muscle by endothelin-1 is mediated by phospholipase C LINDNER R - Regulation of the glutamate transporter EAAT4 by PIKfyve Lindner R. - Regulation of the EAAT3 by PIKfyve LINDQUIST C - GABAA receptors, the channels that grow in conductance Lindqvist R - Cholecystokinin (CCK-8) induced stimulation of duodenal bicarbonate secretion and intracellular calcium signaling is independent of food intake LINDQVIST R - Cholecystokinin but neither ghrelin nor galanin stimulates duodenal mucosal alkaline secretion LINDROOS M - The effect of adenosine, hypoxia and exercise on local skeletal muscle blood flow in humans Lindstrom Jaana - NORDIC WALKING DECREASED CIRCULATING CHEMERIN AND LEPTIN CONCENTRATIONS IN PREDIABETIC MIDDLE-AGED MEN Lindvig A. - Long-term depression of pain perception in man affects peripheral receptive fields   - Long-term depression of pain perception in man affects peripheral receptive fields Link C - Effects of calcium antagonists on veratridine-induced epileptiform activity of hippocampal CA3-neurons Link A. - Voltage-gated sodium channel NaV1.6 is required for stimulus evoked repetitive action potential firing in response to cooling and oxaliplatin in peripheral myelinated axons   - Sea Anemone toxin ATX-II increases resurgent and persistent sodium currents selectively in large diameter sensory neurons   - Oxaliplatin induces Nav1.6-mediated resurgent and persistent currents in large DRG neurons in a temperature dependent manner Link A.S. - Electrophysiological characterization of human stem cell derived nociceptors Linke *W.A. - Smyd2 controls cytoplasmic lysine methylation of Hsp90 and muscle sarcomeric organization   - Myofilament Phosphorylation and Function in Experimental Heart Failure with Preserved Ejection Fraction Linke W - Inter-Species Differences in Developmental Changes of Titin Size, TnI Isoforms, Ca2+ Sensitivity, and Passive Stiffness Linke WA - Thyroid hormone is an important regulator of titin isoform switching in developing rat cardiomyocytes   - Effect of chronic afterload increase on titin expression   - Titin-Isoform Diversity in Relation to Passive and Active Contractile Properties of Rabbit Skeletal Muscles   - Titin is inherently phosphorylated in human heart and alters its stiffness depending on phosphorylation state Linke W.A. - Cyclic GMP Enhancing Therapy Promotes Titin Phosphorylation and Corrects High Cardiomyocyte Passive Stiffness in Diastolic Heart Failure Linke W. A. - Crucial role for Ca2+/calmodulin-dependent protein kinase-II in regulating diastolic stress of normal and failing hearts via titin phosphorylation   - Dynamic regulation of titin stiffness in the Z/I region of the sarcomere Linke W.A. - Insulin as a modulator of cardiac titin   - Probing the local mechanical properties of isolated skeletal myofibrils using atomic force microscopy   - Phosphorylation of muscle LIM protein participates in hypertrophic signaling via the mitogen activated protein kinase and calcineurin signaling pathways   - Protein kinase G mediated phosphorylation of the elastic N2A titin domain   - Small heat shock proteins associate under stress conditions with the elastic titin filaments and provide protection from aggregation   - PKG-mediated phosphorylation of titin N2-B unique sequence is a conserved mechanism in mammalian heart   - Protein phosphatase-5 is a novel titin ligand which dephosphorylates cardiac titin and reduces passive myocyte stiffness   - Coordinated changes in titin phosphorylation increase myofilament stiffness in failing hearts   - Insulin mediates rapid titin phosphorylation via NO-dependent activation of PKG   - Cyclic GMP Enhancing Therapy Promotes Titin Phosphorylation and Corrects High Cardiomyocyte Passive Stiffness in Diastolic Heart Failure   - Protein interactions and phosphorylation of the peripheral Z-disk segment of the sarcomeric protein titin   - Exon Skipping - Or How to Chop a Titan   - Changes in titin domain phosphorylation increase myofilament stiffness in failing hearts Linke WA - Muscle lim protein deficiency dependent changes of the myocardial proteome LINKE WA - Titin Isoforms and Titin-based Stiffness in Diastolic Heart Failure   - PKG-mediated phosphorylation of titin N2-B unique sequence is a conserved mechanism in mammalian heart   - Insulin signaling regulates cardiac titin isoform composition in development and diabetic cardiomyopathy Linn T. - Anti-inflammatory thalidomide improves islet grafts survival and functions in a xenogenic environment Linnane DM - The central and peripheral effects of hyperthermia on voluntary force production in man. Linnarsson D. - Cardiovascular control, exercise and gravity LINNEMANN A - Acute effects of histamine and VEGF on endothelial permeability Linss V - The cochleogram of the guinea pig ? comparison of different approaches to evaluate hair cell loss Linss W - The cochleogram of the guinea pig ? comparison of different approaches to evaluate hair cell loss   - Possibilities and limitations of surface EMG of the back extensors by modelling. Linte R.M. - Evidence for functional expression of TRPV2 in rat DRG neurones Linte R - A high-threshold heat-activated channel in rat DRG resembles TRPV2 Lintges M - Hydrostatic pressure induced ATP-sensitive K+ channel activation depends on pannexin and connexin hemichannel mediated ATP release Lintges M. - Mechanosensitive ATP-release trough pannexin and connexin hemichannels involves activation of ATP-sensitive K+ channels in native pulmonary epithelium (Xenopus laevis) Linthorst A. - Pulsatility as a key aspect of HPA regulation Linz P - Which Neurons Convey ASIC and TRPV1 Currents in Renal Afferent Nerve Fibers ?   - Capsaicin-induced TRPV1-type Currents in Renal Afferent Neurons from AKR and C57BL/6 Mice LIONETTI L - Alterations in hepatic mitochondrial morphology and function in rats fed high fat diet rich in lard or in fish oil   - Cellular mechanisms involved in onset and development of hepatic injury in rats fed high fat diet rich in lard or in fish oil   - High fat induced hepatic steatosis and mitochondrial dynamic behaviour: time-dependent adaptations LIONETTI V - Nestin is a key regulator of cardioprotection and nestin-640 gene therapy rescues infarcted myocardium   - Magnetic resonance imaging with hyperpolarized 13C-pyruvate to study carbohydrate metabolism in vivo LIONETTI L - High Fat diet increases pAMPK-1 in the hyphotalamus   - Dietary supplementation with omega-3-PUFA-rich milk decreases energy efficiency and improves antioxidant and anti-inflammatory status in rodents   - Effect of donkey milk on body composition, triglyceridemia, inflammatory parameters and mitochondrial energy efficiency   - Role of skeletal muscle mitochondria energy efficiency and insulin resistance development in rats fed high fat diet rich in fish oil or lard   - Effect of high fat diet rich in fish oil or in lard on obesity, insulin resistance and hepatic steatosis development in rats: role of hepatic mitochondrial energy efficiency   - High fat diet increases AMPK in the hyphotalamus after 6 weeks of treatment   - Glucose tolerance in high fat diet fed rats is improved by 3,5-diiodo-L-thyronine treatment   - The acute phase protein Haptoglobin affects Apolipoprotein E modulation of cholesterol homeostasis in brain   - 3,5-diiodo-L-thyronine protects against high fat diet induced insulin resistance and glucose intolerance in rats LIONETTI V - Early long-term L-T3 replacement rescues mitochondria and prevents ischemic cardiac remodeling in rats   - A partial knockdown of glucose-6-phosphate dehydrogenase impairs cardiac contractile performance and efficiency, in vivo LIONETTO MG - Cell volume regulation and apoptosis in rat distal colon   - Protective effect of the daily ingestion of a purified anthocyanin extract on serum antioxidant capacity LIONETTO M.G - Cell volume regulation and apoptotic volume decrease in isolated eel enterocytes LIONETTO MG - Study of the actin cytoskeleton in rat colon exposed to osmotic stress by confocal microscopy   - Transepithelial absorption and intracellular antioxidant activity of hydroxytyrosol in rat intestine   - Immunolocalization of the cotransport Na+/K+/2Cl- by confocal microscopy in eel intestinal epithelium exposed to hypertonic stress   - In vitro measurement of the anthocyanin antioxidant activity in a living epithelium   - In vivo effect of anthocianin extract oral administration on rat serum antioxidant activity   - Role of myosin II in the response to hypertonic stress: a study in a native intestinal epithelium   - Anoikis and apoptotic volume decrease in isolated rat distal colon surface cells   - BK channels in the Apoptotic Volume Decrease LIPINSKI H-G - A flexible real time system for molecular imaging by means of Fluorescence Resonance Energy Transfer Lipnik-Stangelj Metoda - Histamine as a regulator of astrocyte function LIPOMA M - Levels of blood lactate and quality of attentional processes Lipp *P. - Basal cardiac calcium signalling is modulated by TRPC1 and TRPC4 channels via a constitutively active background calcium entry   - In a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia dantrolene rescues arrhythmogenic RYR2 defect Lipp P - Is there a calcium signalling in erythrocytes?   - Expression patterns of elements of the Gq-dependent signalling cascade in human cardiac tissue   - Cardiac region dependent Ca2+ signalling in murine atrial and ventricular myocytes   - Long-term expression of a Ca2+ sensor protein in cultured adult rat cardiac myocytes   - High resolution 3D-imaging of isolated cardiac myocytes   - High-resolution real-time confocal microscopy   - Insights into long-term adult cardiac myocytes culture   - Isolation, culture, and morphology of human atrial myocytes   - Effect of chronic Gq-coupled stimulation and Ca2+ handling in long-lasting cultured adult cardiac myocytes   - Efficient T-cell activation requires kinesin/dynein-dependent mitochondrial translocation to the plasma membrane   - Optical recording of PKC-membrane interactions: the PKC pas-de-deux Lipp P. - All-electronic documentation practical course for first year medical students Lipp P - Influence of the anesthetic carbondioxide (CO2) on hormone-induced effects on isolated murine cardiomyocytes LIPP P - Versatile imaging of adult rat ventricular myocytes reveals remodelling of subcellular structures during long-term culture   - Adaption, evaluation and application of optical action potential recording on adult cardiomyocytes   - Subcellular localisation and functional effect of atypical PKC and PKD in rat ventricular myocytes   - Influence of Cytochalasin D on morphology and physiology of rat cardiac myocytes Lipp P. - Characterisation of ventricular myocyte remodelling in RacET mice   - New insights in the consequences of calcium influx in human erythrocytes   - Frequency modulated two-photon uncaging   - Pixel-wise fitting: a robust analytical 3D visualization of calcium handling in cardiac myocytes   - The impact of hyperaldosteronism on cellular excitation and contraction varies within different cardiac myocytes   - Lysophosphatidic acid induced signaling in human and mice erythrocytes   - The electrophysiological effects of chronic application of aldosterone on ventricular myocytes of Gq/11 knock out mice   - Left and Right atria of RacET mice follow a different cellular remodelling   - Cytocalasin D preserves functional parameters in rat ventricular myocytes in culture without mechanical uncoupling   - Web-associated teaching as an alternative in preclinical education   - Excitation-contraction coupling alterations in ventricular myocytes of RacET mice   - Functional and morphological development of hearts from Gq/11 knockout mice LIPPE C - Permeability of three herbicides across the isolated frog and pig skins   - In frog skin, the increase of sodium absorption caused by pesticides is related to their lipid solubility Lips K. - The non-neuronal cholinergic system in mouse tracheal epithelium: Evidence for the participation of muscarinic M1, M3 receptors and nicotinic receptors   - Tuesday, March 24, Hall 4Oral SessionAnion transportChairpersons: J. Deitmer (Kaiserslautern)A. Schwab (Mnster) Nicotine activates chloride channels in mouse tracheal epithelium   - Nicotinic acetylcholine receptors activate ion transport in mouse tracheal epithelium via Ca2+ and cAMP signalling Liptak N. - THE ROLE OF PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE IN MORPHINE WITHDRAWAL-INDUCED ANXIETY AND LOCOMOTOR ACTIVITY IN MICE Liptak N. - ROLE OF OBESTATIN IN MORPHINE-INDUCED BEHAVIORAL RESPONSES   - THE EFFECT OF TYR-D-ALA-GLY-PHE-D-NLE-ARG-PHE, A SYNTHETIC OPIATE ON THE HORMONAL AND BEHAVIORAL STRESS RESPONSE Lipton SA - Role of astrocytic glutamatergic signaling in Abeta oligomers toxicity LIQUORI GE - Aquaglyceroporin AQP9 has patho-physiological relevance in non-alcoholic fatty liver disease (NAFLD)   - Hepatocyte AQP9 and glycerol membrane permeability are decreased in fatty liver disease   - Aquaporin-9 (AQP9) and basolateral osmotic water permeability are reduced in the hepatocytes of rats with extra-hepatic cholestasis Liroa-Romero M - RECOGNITION AND TREATMENT OF AN ACUTE MYOCARDIAL INFARCTION IN A SIMULATED SCENARIO   - A SIMULATED SCENARIO TO TEACH MEDICAL STUDENTS THE PATHOPHYSIOLOGY OF A SEPTIC SHOCK Lis A - TRPM3 is a ionotropic steroid receptor in pancreatic beta cells   - Identification of TRPM3-like currents in native murine cells   - Permeation of mono- and divalent cations through the alpha2 splice variant of TRPM3 channels   - Pharmacological characterization of the Ca2+ permeable channel TRPM3alpha2 LISCIA A - Functional anatomy and the motor programme at the base of calling behaviour in the female gypsy moth Lymantria dispar   - The water taste transduction mechanism in the blowfly couples aquaglyceroporins and stretch-sensitive channels Liskova A. - Effects of transient cerebral ischaemia on the heart mitochondria in the rat Liskova S - Effect of melatonin on reactivity of rabbit blood vessels Liss B. - An exciting role of KATP channels in dopamine midbrain neurons for novelty-coding and for Parkinson disease   - ATP-sensitive potassium channels are crucial modulators of in vivo burst firing in medial substantia nigra dopamine neurons, which control novelty-induced exploratory behaviours   - L-type calcium channels control age-dependent desensitization and cocaine-induced plasticity ofD2-autoreceptor function in substantia nigra dopamine midbrain neurons LISS P - Activation of NADPH oxidase and uncoupling of nNOS result in increase in oxygen consumption in the diabetic kidney Lissandron Valentina - HETEROGENEITY OF Ca2+ HOMEOSTASIS IN THE GOLGI APPARATUS LISSNER S - NHERF2 PDZ-adapter determines the membrane raft association of the apical Na+/H+ exchanger NHE3 in murine small intestine List D. - Hypertrophic cardiomyopathy mutations R723G and R453C in the myosin head homain cause force enhancement by different mechanisms LITTARRU GP - Naturally occurring substances propionyl-L-carnitine, (PLC) coenzyme Q10 (CoQ10) and omega-3 fatty acids (omega-3) exert cardioreparative action on disarrayed geometry and kinetics of myosin molecular motors on BIO TO-2 cardiomyopathic Syrian hamsters Littwitz C - Influence of cTnI-R145G on ventricle cell contraction depends on b-adrenergic receptor stimulation   - Gene-silencing using adenoviral RNAi vectors in adult cardiac myocytes Littwitz C. - Acetylcholine-activated GIRK current (IK(ACh)) provides a sensitive assay for autocrine production and action of extracellular adenosine in rat atrial myocytes in vitro   - Overexpression of A1-adenosine receptors in rat atrial myocytes results in increased functional expression of Kir2 inward-rectifying K+ channels Liu *Z.Z. - A stronger constrictive effect of contrast media on afferent than efferent arterioles in mice Liu H - THYROID HORMONE AND SENSORY FUNCTIONS Liu G. - Up-regulation of the large conductance voltage- and Ca2+-activated K+ channels by Janus-activated kinase JAK2 Liu H. - Controlling inflammatory responses: How ephrinB2 supports vascular remodeling processes Liu I. - Interleukin-1 interferes with sarcoplasmic Ca2+ release through the skeletal muscle ryanodine receptor: a new mechanism explaining muscle failure in critical illness myopathy LIU JQ - Reduction in cardiac Kir3.4 channel expression causes congenital long QT syndrome - A functional role of GIRK currents in ventricular repolarization LIU S - Sildenafil improves synaptic function, memory and Amyloid-beta load in an Alzheimer Mouse Model Liu SX - Neuropeptides and their receptors at the spinal level: Involvement in pain mechanisms Liu X. - Expression and function of Slc26a9 member of the Slc26 anion transporter family in the Gastrointestinal tract LIVERINI G - Increased skeletal muscle mitochondrial efficiency in a model of obesity induced by diets rich in fructose Livet J - Brainbow: Combinatorial expression of fluorescent proteins to visualize neuronal circuits LIVREA MA - Mechanism of action of the betalain pigment indicaxanthin, purified from fruits of Opuntia ficus-indica, on mouse ileal motility in vitro Lizanecz E - DECREASE IN THE ELEVATED SERUM ACE2-ACTIVITY AFTER CARDIAC RESYNCHRONIZATION THERAPY IN PATIENTS WITH SYSTOLIC HEART FAILURE Lizasoain I - ISCHEMIC CASCADE: TARGETS FOR CYTOPROTECTION IN ACUTE ISCHEMIC STROKE LIZIO R - Frontal attentional responses to food size are abnormal in obese subjects: an electroencephalographic study Ljaschenko *D. - Patterns of synaptic plasticity at the Drosophila neuromuscular junction Ljaschenko D. - Influence of chronic neuronal activity on synaptic development   - Extracting single molecule information from super-resolved nanostructures of active zones   - Characterisation of dCIRL in Drosophila melanogaster   - Rabphilin supports evoked synaptic release in Drosophila   - Functional Nanoscopy of Synaptic States LJOSA V - Quantification of subtle cellular phenotypes in microscopy-based high-throughput experiments Ljubojevic S. - Quantification and regulation of nucleoplasmic Ca2+ concentration in cardiac myocytes Ljungvall I - The dog as a genetic model of human cardiovascular disease Llamas MA - CHRONIC AND ACUTE PORTAL HYPERTENSION INDUCE INTESTINAL BACTERIAL TRANSLOCATION TO MESENTERIC LYMPH NODES IN THE RAT Llaneza P - REGULATION OF IRS-1 SERINE/TYROSINE PHOSPHORYLATION BY OVARIAN SEX STEROIDS IN RAT. IMPLICATIONS ON INSULIN SENSITIVITY Llewellyn Smith Ida J - PREPROGLUCAGON (PPG) NEURONS INNERVATE NEUROCHEMICALLY IDENTIFIED AUTONOMIC NEURONS IN THE MOUSE BRAINSTEM LLEWELLYN-SMITH IJ - GLP-1 neurons extensively innervate autonomic control regions of the CNS Llinas MT - ALTERED RENAL HEMODYNAMIC AND EXCRETORY FUNCTION IN RATS WITH A REDUCED NEPHRON NUMBER   - ROLE OF ANGIOTENSIN II IN THE HYPERTENSION ELICITED BY A REDUCTION IN NEPHRON NUMBER DURING RENAL DEVELOPMENT Llinas M - Age- and sex-dependent differences in the hypertension and renal hemodynamic changes in rats with an altered nephrogenesis. Role of angiotensin II.   - Renal hemodynamic angiotensin II effects in male and female rats at different ages. Llobet A - A MUTATION IN THE FIRST INTRACELLULAR LINKER OF CACNA1A MODIFIES P/Q CHANNEL REGULATION, SYNTAXIN 1A BINDING AND LOWERS SECRETION EFFICIENCY: RELEVANCE TO MIGRAINE CLINICAL PHENOTYPE. Llompart I - EFFECTS OF INTENSE EXERCISE ON H2O2 PRODUCTION AND ON THE ANTIOXIDANT ENZYME ACTIVITIES IN PMA-ACTIVATED LYMPHOCYTES Llopis J - IMAGING PROTEIN INTERACTIONS WITH FLUORESCENT PROTEINS Llopis J - FLUORESCENT PROTEIN-AEQUORIN FUSIONS AS IMPROVED BIOLUMINESCENT Ca2+ REPORTERS   - IRONVANADIUM INTERACTIONS IN HEPATOCYTES OF STREPTOZOTOCIN-DIABETIC RATS TREATED WITH VANADIUM MALTOLATE Llorens S - ASSESSMENT OF VASCULAR FUNCTION IN SENESCENCE-ACCELERATED MICE (SAM-P8)   - EFFECTS OF GLITAZONES ON MICROVASCULAR FUNCTION AND AORTA IN GENETIC HYPERTENSION IN RATS Llorens S - EFFECTS OF GLITAZONES ON ENDOTHELIAL FUNCTION AND SMOOTH MUSCLE CALCIUM MOBILIZATION OF MICROVESSELS IN HYPERTENSION AND METABOLIC SYNDROME IN RATS   - Effect of visceral perivascular adipose tissue on endothelial function of mesenteric resistance arteries from Obese Spontaneously Hypertensive (SHROB) and non-obese Wistar Kyoto (WKY) rats. Llorente R - CANNABINOIDS-NICOTINE INTERACTIONS: ANIMAL MODELS OF ADOLESCENCE; IMPLICATIONS FOR FEEDING AND EMOTIONAL RESPONSES Lloret A - Mitochondrial aggregation in apoptosis induced by B-Amyloid in PC12 cells. Lloret A - ROLE OF BCL-2 IN GSH-MEDIATED GENE EXPRESSION   - NUCLEAR GLUTATHIONE IS ESSENTIAL FOR THE ONSET OF CELL PROLIFERATION   - THE -AMYLOID INCREASES THE EXPRESSION OF RCAN   - OXIDATIVE STRESS IS PRESENT IN PRIMARY FIBROBLASTS FROM A KINDLER SYNDROME PATIENT   - DIFFERENT PATTERNS OF IN VIVO PRO-OXIDANT STATES IN A SET OF CANCER-OR AGING-RELATED GENETIC DISEASES   - VITAMIN E PARADOX IN ALZHEIMERS DISEASE: IT DOES NOT PREVENT LOSS OF COGNITION AND MAY EVEN BE DETRIMENTAL   - CHARACTERIZATION OF OXIDATIVE STRESS IN DOWN SYNDROME. IN VITRO AND IN VIVO STUDIES. Lluch P - DIMETHYLARGININE DIMETHYLAMINOHYDROLASE-ASYMMETRIC DIMETHYLARGININE-NITRIC OXIDE SYSTEM (DDAH-ADMA-NO) IN MORBID OBESITY   - PARTICIPATION OF CA2+-ACTIVATED K+ CHANNELS ON ADRENERGIC RESPONSES OF HUMAN SAPHENOUS VEIN.   - DIMETHYLARGININE DIMETHYLAMINOHYDROLASE IN LIVER OF CIRRHOTIC RATS Lo CC - Analysis of Sleep Fragmentation across species Lo D - DELAYED ONSET OF A SLOWLY RECOVERING COMPONENT OF SHORT-TERM DEPRESSION DURING EXHAUSTIVE USE AT EXCITATORY CENTRAL SYNAPSES LO FURNO D - Mesenchymal stem cells from adipose tissue differentiated in chondrocytes express hyaline cartilage markers   - Expression of apoptosis markers in human mesenchymal stem cells from adipose tissue during differentiation into adipocytes LO FURNO D - The effect of Bradykinin on expression of -SMA in human lung fibroblasts cultures   - Involvement of flotillin-2 and caveolin-1 in psychosine-induced apoptosis LO GERFO E - The cerebellum and perceptual learning   - Perceptual and attentional mechanisms within the human lateral occipital (LO) region LO GERFO E1,2 - Enhanced filtering of visual distracters by rTMS of the human LO region LO MARTIRE V - Effects of ambient temperature on cardiovascular control during sleep in narcoleptic mice with genetic ablation of hypocretin neurons LO MARTIRE V - Circadian rhythms of blood pressure occur during each wake-sleep state in mice   - REM sleep entails arterial hypertension in hypocretin-ataxin3 narcoleptic mice   - Central and baroreflex control of heart period as a function of ambient temperature in narcoleptic mice with genetic ablation of hypocretin neurons   - Theta wave bursts during rapid-eye-movement sleep and cataplexy in hypocretin-deificient narcoleptic mice   - The low-frequency fluctuations of blood pressure are not buffered by those of heart period during sleep: a pilot study with fixed-rate atrial pacing in rats LOBACH AS - Effects of intravenously administered nanoparticles on arterial blood pressure and heart rate in rats Lobaton CD - MODULATION OF Ca2+ RELEASE AND CYTOSOLIC Ca2+ OSCILLATIONS BY THE MITOCHONDRIAL Na+/Ca2+ EXCHANGER   - INHIBITION OF THE MITOCHONDRIAL Ca2+ UNIPORTER BY KB-R7943 REVEALS MODULATION BY MITOCHONDRIA OF ENDOPLASMIC RETICULUM Ca 2+ RELEASE   - EFFECTS OF ACTIVATION OF MITOCHONDRIAL Ca2+ UPTAKE ON Ca2+ RELEASE AND Ca2+ OSCILLATIONS   - MITOCHONDRIA: A KEY CONTROLLER OF INTRACELLULAR Ca2+ SIGNALING Lober R - Interactions between GPCR signaling components studied with fluorescence recovery after photobleaching (FRAP) LOBINA A - Hemodynamic effect of acute vasodilatation during postexercise-induced metaboreflex activation Lobotkova J - ASSESSMENT OF GAIT INITIATION PARAMETERS FROM TRUNK ACCELERATIONS AND CAMERA-BASED MOTION CAPTURE SYSTEM   - HOW STANDING ON INCLINED SURFACE AFFECTS FUNCTIONAL LIMIT OF STABILITY?   - VISUAL BIOFFEDBACK MAGNIFICATION IN RELATION TO POSTURAL SWAY LOCATELLI F - Post-synaptic regulation in unipolar brush cell by voltage-dependent currents Loch S - Characterization of TRPM3-like steroid receptors in rodent endocrine cells   - Permeation of mono- and divalent cations through the alpha2 splice variant of TRPM3 channels   - Pharmacological characterization of the Ca2+ permeable channel TRPM3alpha2   - TRPM3 is a ionotropic steroid receptor in pancreatic beta cells   - Identification of TRPM3-like currents in native murine cells Loch S - The fractional calcium current through fast ligand-gated TRPM channels Lochmuller H - The role of TRP channels in differentiating muscle cell lines from normal and dystrophic mdx mice LOCHOVSKY C - A polymer chip-based technology for the investigation of small resistance arteries Lockridge O. - AChE knockout mice/receptor adaptation mechanisms in AChE-/- mice Lodewick C. - Influence of hypoxia inducible factor (HIF)-1 deficiency in dendritic cells on the course of acute and chronic viral infections   - Hypoxia inducible factor-1 drives type I interferon expression in dendritic cells LODI L - Training of skilled motor actions and movement related brain macropotentials Loeh B - Downregulation of beta receptor signalling in alveolar epithelial cells in hypoxia Loerinczi Ï - Voltage dependence of transient and stationary photocurrents of Proteorhodopsin expressed in Xenopus laevis oocytes   - Voltage dependence of transient and stationary photocurrents of Proteorhodopsin expressed in Xenopus laevis oocytes   - Voltage dependence of transient and stationary photocurrents of Proteorhodopsin expressed in Xenopus laevis oocytes   - Effects of sequence variation on plasma membrane localization of Wilson Disease Protein expressed in Xenopus laevis oocytes   - Effects of sequence variation on plasma membrane localization of Wilson Disease Protein expressed in Xenopus laevis oocytes   - Effects of sequence variation on plasma membrane localization of Wilson Disease Protein expressed in Xenopus laevis oocytes Loetsch M - The endothelial glycocalyx prefers albumin for evoking shear-stress induced, NO mediated coronary dilatation Loffing J - Dietary Na intake regulates the expression of the ubiquitin-protein ligase Nedd4-2 in mouse kidney LOFFING J - Acidosis in mice lacking aldosterone synthase Loffing-Cueni D - Dietary Na intake regulates the expression of the ubiquitin-protein ligase Nedd4-2 in mouse kidney Loffler BG - Calcium signals in murine intestinal lymphocytes LOFGREN M - Milk Sugar Test: social competition model for study of direct effect of GABAA receptor active compounds Login Cristian Cezar - THE ANTIOXIDANT EFFECT OF CHITOSAN IN CARBON TETRACHLORIDE-INDUCED HEPATITIS IN RATS LOGIN C - The protective effect of chitosan against oxidative injuries induced by chronic exposure to carbon tetrachloride Login C. - Non-invasive oxidative stress markers for liver fibrosis development in toxic hepatitis evolution LOGOTHETIS NK - In vivo Connectivity: Paramagnetic Tracers, Electrical Stimulation & Neural-Event Triggered fMRI Logunova L. - The tau mutation in mice and hamsters Loh B. - Beta-adrenergic stimulation prevents inhibition of alveolar Na-transport in hypoxia LOH YP - C-terminal Chromogranin A-derived Serpinin and pyroglutaminated serpinin as novel cardiac -adrenergic agonists Lohinai Zs. - NEW APPROACH IN VITAL MICROSCOPY: THREE-DIMENSIONAL TRANSPARENT IMAGING Lohmann C. - Tuesday, March 24, Audimax, Poster Area GPoster Session: Vascular function and remodelingModerators: R. P. Brandes (Frankfurt a. M.)G. Siegel (Berlin) Diet-induced obesity increases plasma aldosterone and impairs endothelial function Lohmann Ebba - EVALUATION OF COGNITIVE DEFICITS IN PATIENTS WITH PARKIN (PARK2) GENE MUTATIONS USING AUDITORY EVENT-RELATED POTENTIALS Lohmer S. - Mitochondrial Ca2+mobilization is a key element in olfactory signaling Lohmuller B. - The role of the CaV1.2 L-type calcium channel in smooth muscle tissues LOHN M - Inhibition of the small GTP-binding proteins RhoA and Rac prevents vascular dysfunction in chronic renal failure in mice Lohn M. - Rho kinase inhibition more potently inhibits endothelin-1-induced constriction in renal than in non-renal resistance arteries Lohner K - Effects of flavonoids on p-glycoprotein expression in intestinal epithelial cells Lohner R - In vivo application of Eritoran restores cardiac function during endotoxemia LOIACONO A - Reduced effects of pacing respiration at 0.2 Hz on heart rate variability in migraineurs   - Reduced effects of pacing respiration at 0.2 Hz on heart rate variability in fibromyalgic women LOIODICE F - Effects of novel sintetic peroxisome proliferator-activation receptor (PPARs) agonist on neuronal differentiation in the human neuroblastoma SH-SY5Y cell line LOKKA G - Vessel permeability of a macromolecular contrast agent in mouse muscle using Magnetic Resonance Imaging (MRI) Loma P - siRNA: ITS THERAPEUTIC POTENTIAL IN THE TREATMENT OF OCULAR HYPERTENSION AND GLAUCOMA Lombardi *G. - Relationship between osteocalcin, undercarboxylated osteocalcin and markers of energy status in elite cyclists during the Giro dItalia three weeks-long stage race LOMBARDI A - Metabolic effects exerted by 3,5-diiodothyronine : focus on brown adipose tissue   - 3,5-diiodothyronine (T2) activates brown adipose tissue oxidative capacity: a morphological and functional study LOMBARDI L - Responsiveness to NGF is reduced in sympathetic neurons of mdx mice, affecting axon outgrowth and regeneration both in vivo and in vitro LOMBARDI V - The elasticity and the working stroke of the myosin motor in muscle LOMBARDI A - Role of uncoupling protein 3 in the translocation of lipid hydroperoxide across the mitochondrial inner membrane and in inducing lipid hydroperoxide-dependent mitochondrial uncoupling   - A combined Blue Native- and 2D-electrophoresys approach to study rat fatty liver proteome following 3,5-diiodothyronine treatment   - High fat diet-induced insulin resistance: effects of 3,5-diiodo-L-thyronine on muscle mitochondrial proteome and function.   - Role of AMPK in the organ-specific responses to 3,5-diiodo-L-thyronine in high-fat diet-fed rats   - Response of rat gastrocnemius skeletal muscle lipid metabolism to iodothyronines administrations: focus on FAT/CD36   - 3,5-diiodo-L-thyronine protects against high fat diet induced insulin resistance and glucose intolerance in rats   - Influence of 3,5-diiodo-L-thyronine on cellular distribution of FAT/CD36 in skeletal muscle: a morphological approach   - Influence of 3,5-diiodo-L-thyronine on skeletal muscle lipid metabolism.   - Rapid effect of 3,5-diiodo-L-thyronine on skeletal muscle mitochondrial fatty acid oxidation rate and thermogenesis   - Glucose tolerance in high fat diet fed rats is improved by 3,5-diiodo-L-thyronine treatment   - Rapid activation by 3,5,3-L-triiodothyronine of AMPK/ACC and Akt/PKB signaling pathways in rat gastrocnemius muscle in vivo Lombardi G. - Evaluation of bone metabolism in elite cyclists during the Giro dItalia three weeks-long stage race LOMBARDI L - Functional characterization of neuronal nicotinic receptors in sympathetic neurons of wild type and dystrophic mdx mice   - PACAP-38 induces sensitisation in the leech Hirudo medicinalis   - Components of the NGF signaling complex are altered in mdx mouse superior cervical ganglion and its target organs   - Lack of dystrophin affects axon regeneration in vivo and neurite outgrowth in vitro   - Reduced neurite growth of cultured sympathetic neurons from dystrophic mdx mice LOMBARDI M - Magnetic resonance imaging with hyperpolarized 13C-pyruvate to study carbohydrate metabolism in vivo LOMBARDI V - Toward the construction of a myosin based machine   - Structural changes in muscle during relaxation   - The molecular mechanism of the response of skeletal muscle to stretch   - Mechanics of the unwinding of DNA helix under force clamp   - The effect of inorganic phosphate on transient and steady state responses of demembranated fibres from skeletal muscle   - A low angle X-ray diffraction study of the relaxed and activated states of skinned fibres of rabbit psoas muscle   - Orthophosphate and orthovanadate inhibit isometric force via two different pathways of the acto-myosin ATPase cycle   - X-ray diffraction estimate of the relative contributions of subfragment-1 and -2 of the myosin molecule to the compliance of muscle cross-bridges   - DNA unwinding under force clamp and its dependence on temperature   - Kinetics of the increase in stiffness following stretches superposed on the isometric contraction of single muscle fibres   - N-benzyl-p-toluene sulphonamide (BTS) used to test force generation kinetics of myosin motors in muscle   - Structural changes in the myosin motors during activation and force generation of muscle   - A dual-laser optical-tweezers for mechanical measurements on single molecules and filaments   - Relative contribution of attached and detached myosin heads to the X-ray pattern determined in muscle fibers contracting at different sarcomere lengths   - Structural changes in myosin motors and filaments during unloaded shortening and isometric force redevelopment after shortening   - X-ray diffraction study of the effect of temperature on the structure of mammalian muscle at rest and during isometric contraction   - The effect of phosphate on the mechanics and energetics of the isometric contraction of skeletal muscle LOMBARDO P - Serotonergic modulation of cerebellar granular layer activity LOMBARDO L - Antiepileptic drugs induce drug-resistance proteins and nuclear receptors in the brain microvascular endothelial cells LOMBARDO P - Alpha7 nicotinic receptor activation enhances neurotransmission and plasticity in the cerebellar glomerulus   - Complex dynamics in the granular layer network of the cerebellum: experimental results and computational reconstructions   - Alfa-7 nicotinic receptors enhance glutamatergic transmission and plasticity in the cerebellum LOMBARDO X - Theta-frequency resonance emerges from intrinsic properties of neurons and synapses in the cerebellum granular layer circuit Lomo T - Plateau potentials in motoneurones contribute to body temperature regulation   - Developmental fates of satellite cells in regenerating fast and slow muscles of adult rats Loncar-Stevanovic H. - Dose-dependent antiseizure effects of ethanol on experimental lindane-induced epilepsy in rats   - EKG and EEG changes during tonic seizures in metaphit-injected rats challenged by sound stimulation LONG X - MicroRNAs and SMC Phenotype LONGA E - Modifications in specific force and myosin concentration in aging and disuse LONGA E - Temperature dependence of MgATP and MgADP affinity of fast and slow rat myosin isoforms: an IVMA approach Longhi Renato - Oxytocin receptor coupling to different G-proteins: role in receptor trafficking LONGONE P - Distribution of group II metabotropic glutamate receptors in the spinal cord of G93A-SOD1 mice, an animal model of amyotrophic lateral sclerosis LONOBILE G - Comparison of effects of Valproate and the newly synthesized Valproil-L-Tryptophan on epileptiform activity in rat brain slices   - Evidences of cannabinoids-induced modulation of paroxysmal events in an experimental model of partial epilepsy in the rat   - Nitric oxide-active compounds modulate the intensity of glutamate-evoked responses in the globus pallidus of the rat   - Evidences of cannabinoids-induced modulation of paroxysmal events in an experimental model of partial epilepsy in the rat LOOSE KO - Ryanodine receptor sensitivity determines Ca2+ wave velocity in cardiomyocytes LOOSER P - Monitoring of junior competitive cyclists over the competition period reveals a load-dependent slow to fast phenotype fiber shift decreasing cycling efficiency Loot *A. - 11,12-Epoxyeicasotrienoic acid contributes to hypoxic pulmonary vasoconstriction by activating mitochondrial large-conductance potassium channels through the 1 subunit Loot AE - TRPV4 plays a crucial role in NO- and prostacyclin- independent, flow-induced vasodilatation Loot A. - Angiotensin II impairs endothelial function through PYK2-dependent tyrosine phosphorylation and inactivation of eNOS   - The AMP-activated protein kinase modifies gene expression in endothelial cells by interfering with protein lysine acetylation   - Interfering with the association of A kinase anchoring proteins (AKAPs) to PKA prevents the fluid shear stress induced phosphorylation of eNOS in endothelial cells Loot A.E. - Pharmacological inhibition of the proline-rich tyrosine kinase PYK2 improves eNOS-dependent VEGF-induced angiogenesis LOOT AE - Angiotensin II causes endothelial dysfunction through tyrosine phosphorylation and inactivation of eNOS: role of Pyk2, Nox2 and H2O2.   - A high fat Western diet attenuates Ca2+-sensing receptor-dependent vascular responses.   - Fluid shear stress increases A kinase anchoring protein (AKAP) 12 expression and changes its intracellular localisation in human endothelial cells LOOT AEL - Lack of effect of the AMP-activated protein kinase (AMPK) on the activity of the endothelial nitric oxide synthase (eNOS) Lopatina L.P. - Lanthanides induce neurotransmitter release from the vesicular pool in presynaptic brain endings Lopez FJ - CELLULAR DISTRIBUTION OF GALANIN AND ITS SUBTYPE 2 RECEPTOR IN THE ANTERIOR PITUITARY GLAND OF FEMALE RATS DURING ESTROUS CYCLE Lopez JJ - Platelet PMCA activity in patients with non-insulin dependent diabetes mellitus is reduced by endogenously generated reactive oxygen species   - Non-apoptotic caspase-3 activation is necessary for cellular function   - BID AND BAX PROTEINS PARTICIPATE IN THROMBIN-INDUCED HUMAN PLATELET APOPTOSIS.   - 5,6-Epoxyeicosatrienoic acid is involved in Ca2+ entry by de novo conformational coupling in human Platelets   - INVOLVEMENT OF CALCIUM IN H2O2-INDUCED APOPTOSIS IN RAT PANCREATIC ACINAR AR42J CELLS   - A role for PKC in the translocation of caspases 3 and 9 to the cytoskeleton Lopez L - TRAINING INCREASES INTRINSIC ATRIOVENTRICULAR CONDUCTION SYSTEM REFRACTORINESS Lopez Miguel - Role of hypothalamic fatty acids, AMPK and ghrelin in the regulation of food intake Lopez A - CoQ Biosynthesis and Genotype-Phenotype Relationships in New Mouse Models of Primary CoQ Deficiency   - LIVER AND BRAIN SUBCELLULAR DISTRIBUTION AND SYNTHESIS REGULATION OF MELATONIN   - CONSTITUTIVE MITOCHONDRIAL NITRIC OXIDE SYNTHASE AND MITOCHONDRIAL BIOENERGETICS DURING SEPSIS. ROLE OF MELATONIN.   - BENEFICIAL EFFECTS OF TOPIC MELATONIN ADMINISTRATION AGAINST MITOCHONDRIAL DAMAGE DURING RADIOTHERAPY-INDUCED MUCOSITIS   - MELATONIN PROTECTS NORMAL MITOCHONDRIA FROM OXIDATIVE DAMAGE REDUCING SUPEROXIDE ANION PRODUCTION.   - CoQ deficiency: molecular and pathophysiological consequences. Lopez B - GENDER DIFFERENCES IN OXIDATIVE AND NITROSATIVE STRESS DURING RENAL ISCHEMIA   - THE BODY MASS INDEX AND LIPID PROFILE ARE THE MOST INFLUENTIAL FACTORS ON OXIDATIVE STRESS IN THE HUMAN AGEING CARDIOVASCULAR SYSTEM. Lopez JI - EXPRESSION OF CB1 CANNABINOID RECEPTOR IN FETAL AND ADULT HUMAN KIDNEY LOPEZ JJ - TRPA1 plays a functional role in the megakaryoblastic cell line MEG01 Lopez JJ - APOPTOSIS TRIGGERED BY ENDOPLASMATIC RETICULUM STRESS IS ASSOCIATED TO CASPASES 3, 8 AND 9 ACTIVATION IN HUMAN PLATELETS   - H2O2-INDUCED CASPASE ACTIVATION IS DEPENDENT OF CALCIUM SIGNAL IN HL-60 CELLS Lopez L - IS THE TRAINING-INDUCED INCREASE OF INTRINSIC VENTRICULAR REFRACTORINESS MEDIATED BY POSTGANGLIONIC PARASYMPATHETIC NEURONS ACTIVITY? AN EXPERIMENTAL STUDY.   - CELLULAR AND MOLECULAR BASIS OF THE RADIOTHERAPY-INDUCED MUCOSITIS. EXPERIMENTAL EVALUTION OF THE BENEFICIAL THERAPY WITH MELATONIN   - EFFECTS OF MELATONIN ON NEURAL STEM CELL VIABILITY AND DIFFERENTIATION: ROLE OF THE MITOCHONDRIA Lopez L.C - Modulation of the NF-kappaB pathway by melatonin in septic aged mice Lopez LC - CoQ Biosynthesis and Genotype-Phenotype Relationships in New Mouse Models of Primary CoQ Deficiency   - PREVENTION OF AGE-DEPENDENT OXIDATIVE DAMAGE AND INFLAMMATION BY CHRONIC MELATONIN ADMINISTRATION   - CoQ deficiency: molecular and pathophysiological consequences.   - Unstable Mitochondrial Supercomplexes Contributes to the Pathophysiology of CoQ Deficiency Syndrome   - MELATONIN PROTECTS NORMAL MITOCHONDRIA FROM OXIDATIVE DAMAGE REDUCING SUPEROXIDE ANION PRODUCTION.   - BENEFICIAL EFFECTS OF TOPIC MELATONIN ADMINISTRATION AGAINST MITOCHONDRIAL DAMAGE DURING RADIOTHERAPY-INDUCED MUCOSITIS   - Melatonin modulation of the NF-kappaB signaling pathway in sepsis.   - Melatonin, nitric oxide synthases and Parkinson's disease Lopez M - CHRONIC CENTRAL ADMINISTRATION OF AMYLIN DECREASES FAT MASS BUT DOES NOT MODIFY BODY WEIGHT   - IS CIDEA MEDIATING HIGH FAT DIET INDUCED GHRELIN RESISTANCE?   - Leptin and Fasting Regulate Rat Gastric Glucose-Regulated Protein 58   - Nicotine regulates energy balance through hypotalamic AMP-activated protein kinase in rats fed in high fat diet   - Adipose and Liver lipid metabolism are influenced by central Melanin-Comcentrating Hormone   - p53 mediates the adipogenic effect of ghrelin   - Antipsychotic-induced metabolic adverse effects - is hypothalamic lipid metabolism involved?   - HYPOTHALAMIC MTOR SIGNALING MEDIATES THE OREXIGENIC ACTION OF GHRELIN   - Hypothalamic Kappa Opioid Receptor Modulates the Orexigenic Effect of Ghrelin   - The lack of Nur77 affects energy and glucose metabolism in females fed on high fat diet.   - Thyroid hormone-induced hyperphagia in hyperthyroidism is mediated by hypothalamic mtor pathway   - Deficiency of Endoglin Protects Against High Fat Diet-Induced Insulin Resistance Lopez V - Effects of extracts obtained from wine by-products on isolated rat duodenum   - Biological activity of Borago officinalis on isolated rat smooth muscle and antioxidant capacity Lopez Barneo J - Hypoxic-induction of T-type calcium channels involves HIF-1a and RhoA/ROCK signaling in neonatal rat cardiac myocytes Lopez Bendito G - Metabotropic receptor signaling in the developing brain Lopez Davila A. - Is contraction or relaxation of rabbit psoas myofibrils rate-limited by Ca2+-regulated switch of the troponin complex?   - Transgenic mice with a low expression rate of the FHC-linked mutation cTnI-K184 exhibit predominantly signs of diastolic dysfunction Lopez de Jesus M - BRAIN CB1 AND PHOSPHORYLATED CB1 CANNABINOID RECEPTOR EXPRESSION IS INCREASED IN OBESE ZUCKER RATS Lopez de Oyague S - MELATONIN BLOCKS NICOTINIC CHANNELS IN CEREBELLAR GRANULE CELLS Lopez de Pablo AL - Influence of maternal undernutrition on mechanical properties of the aorta in the offspring   - Maternal undernutrition in rats induces early heart hypertrophy in young male and female offspring Lopez Novoa JM - OXYGEN FREE RADICALS, RENAL AGING AND HYPERTENSION Lopez Novoa JM - A ROLE FOR NITRIC OXIDE IN THE ISCHEMIA/REPERFUSION INJURY IN THE KIDNEY Lopez Patino M. A. - A metabolic fatty acid sensing mechanism is present in central and peripheral tissues of rainbow trout Lopez Pingarron L - Oxidative stress and aging in duodenal nervous plexus Lopez Ramirez A. - Melatonin, nitric oxide synthases and Parkinson's disease Lopez-Barneo J - DOWN-REGULATION OF MAXI-K CHANNEL b1-SUBUNIT BY HYPOXIA IN CARDIAC MYOCYTES; ROLE IN HYPOXIC PRECONDITIONING   - REGULATION OF AQP1 EXPRESSION BY HYPOXIA IN ENDOTHELIAL CELLS   - Metabotropic Ca2+-channel-induced Ca2+ release; modulation by ATP and hypoxia Lopez-Barneo J - Role of L-type Ca2+ channels, sarcoplasmic reticulum and RhoA/Rho-associated kinase in the maintenance of arterial contraction   - METABOTROPIC Ca2+ RELEASE FROM SARCOPLASMIC RETICULUM PARTICIPATES IN Ca2+ CHANNEL-DEPENDENT CONTRACTION IN BASILAR ARTERY Lopez-Barroso D - 5-HT1A RECEPTOR ACTIVATION PREVENTS THE ONSET OF LEARNED HELPLESSNESS BY TARGETING LOWER BRAIN STEM SEROTONERGIC AND NORADRENERGIC NUCLEI Lopez-Burillo S - MELATONIN EFFECT ON CELLULAR PROLIFERATION AND APOPTOSIS IN RAW 264.7 CELLS. Lopez-Calderon A - EFFECT OF GHRELIN ON SKELETAL MUSCLE CELLS DIFFERENTIATION AND PROLIFERATION.   - MSH TREATMENT HAS AN ANTI-INFLAMMATORY EFFECT AND AMELIORATES ARTHRITIS-INDUCED MUSCLE ATROPHY   - PPAR AGONIST FENOFIBRATE DECREASES MUSCULAR ATROGENES AND MYOSTATIN GENE EXPRESSION IN ARTHRITIC RATS Lopez-Davila A. - Modelling of the fast kinetics observed with skeletal and cardiac troponin reveals differences in their mechanisms LOPEZ-GARCIA MÁ - Antiproliferative and proapoptotic activities of hydroxytyrosol derivatives on human promyelocytic leukemia cell lines Lopez-Gines C - ANGIOTENSIN-II INDUCES DIFFERENTIAL EXPRESSION OF FRACTALKINE AND MONONUCLEAR CELL RECRUITMENT IN HUMAN ARTERIAL OR VEIN ENDOTHELIAL CELLS Lopez-Gonzalez MV - EFFECTS OF HYPOTHERMIA ON THE INHIBITION OF THE BARORECEPTOR RESPONSE EVOKED TO STIMULATION OF THE CAUDAL PERIFORNICAL HYPOTHALAMUS. A FREQUENCY DOMAIN APPROACH TO AUTONOMIC CARDIOVASCULAR CONTROL Lopez-Gonzalez MV - INTERACTION BETWEEN THE DORSOLATERAL PERIAQUEDUCTAL GRAY MATTER (DL-PAG) AND THE A5 REGION. ROLE OF GLUTAMATE Lopez-Grueso R - INDUCCIÓN DE LA EXPRESIÓN DE SIRTUINAS EN MOSCAS DROSOPHILA MELANOGASTER POR EL CONSUMO DE ETANOL Lopez-Grueso R - ESTROGENS PROTECT AGAINST OXIDATIVE STRESS IN TYPE 2 DIABETES   - Identification of plasma biomarkers of frailty in humans   - NUTRITIONAL MODULATION OF SIRTUIN EXPRESSION IS MEDIATED BY REDOX CHANGES   - DIETARY SOY ISOFLAVONES SHOW BENEFICIAL METABOLIC EFFECTS IN MALE MICE: A NUCLEAR MAGNETIC RESONANCE STUDY   - Evaluation of rat brain glucose consumption by means of semi-automatic positron emission tomography image analysis.   - Effect on longevity genes by red wine consumption in nuns   - LOW IN VIVO BRAIN GLUCOSE CONSUMPTION AND HIGH OXIDATIVE STRESS IN ACCELERATED AGING   - DIRECT ANTIOXIDANT AND PROTECTIVE EFFECT OF ESTRADIOL ON ISOLATED HEPATIC MITOCHONDRIA   - IMPORTANCE OF THE INITIATION OF ESTROGEN REPLACEMENT THERAPY AFTER OVARIECTOMY ON OXIDATIVE STRESS PARAMETERS AND IN VIVO GLUCOSE UPTAKE Lopez-Hernandez FJ - FLUVASTATIN INHIBITS THE EXPRESSION OF EXTRACELLULAR MATRIX COMPONENTS IN CANCER CELLS.   - IDENTIFICATION OF NEW URINE MARKERS ASSOCIATED TO GENTAMICIN-INDUCED RENAL DAMAGE Lopez-Hernandez FJ - Excretion of KLK9 in the urine is associated to sustained hypertension, aorta wall thickening and cardiac hypertrophy. Lopez-Jurado M - EFFECTS OF TWO FUNCTIONAL INGREDIENTS ON FOOD INTAKE, NUTRIENT DIGESTIBILITY AND BODY WEIGHT GAIN IN RATS   - INFLUENCE OF TWO FUNCTIONAL INGREDIENTS ON THE PLASMA CONCENTRATIONS OF INSULIN, LEPTIN, GHRELIN AND PEPTIDE YY (PYY) IN RATS Lopez-Lopez JR - ASSOCIATION OF Kv4.3 WITH DPPX MODIFIES DRUG SENSITIVITY OF THE HETEROMULTIMERS   - A NEW ROLE OF Kv3.4 CHANNELS AS MODULATORS OF PROLIFERATION, MIGRATION AND CELL CYCLE PROGRESSION IN HUMAN UTERINE ARTERY SMOOTH MUSCLE CELLS.   - MODULATION OF Kv2.1 ASSEMBLY CONTRIBUTES TO THE CHANGES IN VASCULAR SMOOTH MUSCLE CELL EXCITABILITY IN A HYPERTENSIVE MICE STRAIN Lopez-Menduina M - PPAR AGONIST FENOFIBRATE DECREASES MUSCULAR ATROGENES AND MYOSTATIN GENE EXPRESSION IN ARTHRITIC RATS   - EFFECT OF GHRELIN ON SKELETAL MUSCLE CELLS DIFFERENTIATION AND PROLIFERATION.   - MSH TREATMENT HAS AN ANTI-INFLAMMATORY EFFECT AND AMELIORATES ARTHRITIS-INDUCED MUSCLE ATROPHY Lopez-Millan MB - MEMBRANE ENRICHMENT WITH SPECIFIC FATTY ACIDS (OLEIC ACID OR W3 PUFA) MODIFIES THE INFLAMMATORY RESPONSE IN CERULEIN-STIMULATED AR42J CELLS   - IMPAIRMENT OF CALCIUM HOMEOSTASIS AND SECRETORY RESPONSE IN AR42J CELLS AFTER CERULEIN TREATMENT. INFLUENCE OF CHANGES IN MEMBRANE FATTY ACID PROFILE.   - MODIFICATION OF MEMBRANE FATTY ACID COMPOSITION AFFECTS CELL DEATH AND ANTIOXIDANT DEFENCES IN CERULEIN-STIMULATED AR42J CELLS.   - ADAPTATION OF MEMBRANE LIPID PROFILE AND AMYLASE SECRETION OF AR42J CELLS TO FATTY ACIDS IN CULTURE MEDIUM: INFLUENCE OF EXPOSURE PERIOD   - MODIFICATION OF MEMBRANE FATTY ACID COMPOSITION OF PANCREATIC AR42J CELLS INFLUENCES BILE ACID-INDUCED Ca2+ RESPONSES Lopez-Novoa JM - H- AND N-RAS ISOFORMS MODULATES DIFFERENTIALLY EXTRACELLULAR MATRIX SYNTHESIS AND PROLIFERATION INDUCED BY TRANSFORMING GROWTH FACTOR-BETA 1   - IDENTIFICATION OF NEW URINE MARKERS ASSOCIATED TO GENTAMICIN-INDUCED RENAL DAMAGE   - FLUVASTATIN INHIBITS THE EXPRESSION OF EXTRACELLULAR MATRIX COMPONENTS IN CANCER CELLS.   - ANTIDIABETIC EFFECTS OF SILYBIN: SILYBIN INHIBIT GLUCAGON-INDUCED STIMULATION OF HEPATIC GLYCOGENOLYSIS AND GLUCONEOGENESIS IN PERIFUSED LIVER CELLS. Lopez-Novoa J - Role of endoglin in wound repair in adult endoglin heterozygous mice   - Deficiency of Endoglin Protects Against High Fat Diet-Induced Insulin Resistance Lopez-Novoa JM - K-RAS ISOFORM REGULATES FIBROBLASTS PROLIFERATION AND CELL MOTILITY TROUGH ERK AND AKT ACTIVATION.   - Excretion of KLK9 in the urine is associated to sustained hypertension, aorta wall thickening and cardiac hypertrophy.   - L-endoglin and S-endoglin differentially modulate TGF-beta induced fibrotic responses. Role of p38 and ERK1/2 MAPK   - ALK1 HETEROZYGOUS DISRUPTION INCREASES RENAL FIBROSIS FOLLOWING URETERAL OBSTRUCTION DUE TO A HIGHER SMAD3 PHOSPHORYLATION   - K-Ras isoform modulates extracellular matrix synthesis through Erk and Akt signalling. Lopez-Oliva ME - MODULATION OF SKELETAL MUSCLE NUCLEASES BY GROWTH HORMONE TREATMENT Lopez-Oliva MaE. - THE EFFECTS OF DIETARY PROTEIN RESTRICTION ON rhGH ANTI-ATHEROGENIC AND ANTIOXIDANT ACTIVITY Lopez-Patino M.A. - Melatonin synthesis in trout pineal organ is influenced by stress. Lopez-Pingarron L - Cellular membrane fluidity levels and lipid peroxidation during experimental pancreas transplantation   - Effects of acute and chronic exercise on cell and mitochondrial membrane fluidity in skeletal and cardiac muscles LOPEZ-PINGARRON L. - Effect of tryptoline in stabilizing membranes against oxidative stress Lopez-Pingarron L. - N-acetyl-serotonin prevents membrane rigidity of hepatocytes due to oxidative stress Lopez-Ramos JC - AN IN VIVO STUDY OF CA1-PREFRONTAL SYNAPSE PROPERTIES DURING A CLASSICAL CONDITIONING EYEBLINK PARADIGM IN SAMP8 EARLY-AGING MODEL OF ACCELERATED SENESCENCE Lopez-Rivas Abelardo - AMP-activated protein kinase serves as a universal regulator of autophagy Lopez-Rodas G - UP-REGULATION OF GAMMA-GLUTATMYL CYSTEINE FAILS IN NECROTIZING ACUTE PANCREATITIS Lopez-Rodas G - LOSS OF PP2A SER/THR PHOSPHATASE ACTIVITY AND EPIGENETIC REGULATION OF PRO-INFLAMMATORY GENES IN ACUTE PANCREATITIS Lopez-Sanchez R - OXIDATIVE DAMAGE IN YOUNG PEOPLE BY ALCOHOLIC BEVERAGES CONSUMPTION Loppnow H. - Modulation by lipopolysaccharide of cardiac pacemaker channel activity critically depends on the presence of Lipid A and the O-chain polysaccharide   - Lipopolysaccharide modulates cardiac pacemaker function by reduction of HCN channel activity Lora AJ - RESPIRATORY RATE, HEART RATE AND OXIMETRY ALTERATION DUE TO THE USE OF KETAMINE IN ASSOCIATION WITH DIFFERENT DEPRESSORS Lorand T. - MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF): THE DOYEN OF CYTOKINES IS STILL A MOST INTERESTING FACTOR Lorenc A. - Turkey retina and pineal gland differentially respond to prolonged exposure to constant darkness and light: studies on serotonin N-acetyltransferase activity Lorenz G. - Wednesday, March 25, Hall 4Oral SessionVascular inflammation: Clinical aspectsChairpersons: W. Franz (Mnchen)A. Grlach (Mnchen) The renin-angiotensin system as a primary cause in the pathophysiology of polyarteritis nodosa in rats LORENZETTO E - Rac1 activation improve retina ganglion cells survival and regeneration by ERK1/2 and Pak LORENZI B - Use of bone marrow derived mesenchymal stem cells for muscle regeneration in a model of rat anal sphincters injury LORENZI M - Use of bone marrow derived mesenchymal stem cells for muscle regeneration in a model of rat anal sphincters injury Lorenzo-Diaz F - Heat-shock protein 90 acetylation regulates mineralocorticoid receptor subcellular localization and ligand-induced nuclear translocation LORENZON P - Neural agrin enhances the regenerative potential of aged human skeletal myoblasts   - Adenosine-mediated modulation of the embryonic isoformof the muscle nicotinic acetylcholine receptor LORENZON P - Aggregation of the nAChRs favours Ca2+ spiking and twitching in mouse myotubes during myogenesis   - Effects of hydrogen peroxide (H2O2) on electrical membrane properties of skeletal muscle myotubes   - Age-dependent effect of Hydrogen peroxide (H2O2) on skeletal muscle cells and neuromuscular transmission Lorenzon Paola - The role of reactive oxygen species on proliferation and Ca2+ signalling of skeletal muscle cells during IN VITRO ageing   - Neuronal functional differentiation in mammalian postnatal stem/precursor cells LORENZONI P - Use of bone marrow derived mesenchymal stem cells for muscle regeneration in a model of rat anal sphincters injury Loria A - ALTERED RENAL HEMODYNAMIC AND EXCRETORY FUNCTION IN RATS WITH A REDUCED NEPHRON NUMBER   - ROLE OF ANGIOTENSIN II IN THE HYPERTENSION ELICITED BY A REDUCTION IN NEPHRON NUMBER DURING RENAL DEVELOPMENT Lorincz O. - DIFFERENTIAL EFFECTS OF CALORIC-RESTRICTION ON LEPTIN-INDUCED HYPERMETABOLISM AND ANOREXIA IN MIDDLE-AGED (LEPTIN-RESISTANT) RATS Lorinczy D. - SKELETAL ACTIN DYNAMICS WITH DIFFERENT BOUND NUCLEOTIDES Lornejad-Schafer *M.R. - Reduced bioavailability of Acetaminophen and of co-administered substances across an intestinal barrier model through different mechanisms LORUSSO D - Effect of hydroxytyrosol on motility and permeability in human colonic circular muscle and mucosa respectively Losada M - ANGIOTENSIN-II INDUCES DIFFERENTIAL EXPRESSION OF FRACTALKINE AND MONONUCLEAR CELL RECRUITMENT IN HUMAN ARTERIAL OR VEIN ENDOTHELIAL CELLS LOSANO G - Contribution of antioxidant compound to the protective effect of nitric oxide donors LOSANO G - Myocardial protection by the endogenous peptide Apelin-13   - Ischemia-induced increase of APJ mRNA and protein level and myocardial protection by Apelin-13   - Nitric oxide and antioxidant activity in the protection of the heart ischemia/reperfusion injury Losciuto S. - MODULATION OF MICROGLIA-ASTROCYTE INTERACTION THROUGH LXR ACTIVATION Losekoot M. - A bone overgrowth disorder due to a gain-of-function mutation of guanylyl cyclase B, the receptor for C-type natriuretic peptide Losel C. - Functional Interaction between Smooth Muscle Cells, ICCs, and Nerve Plexus in Uterine Smooth Muscle (USM) Loser S. - Sensitization of afferent nerve fibers by TNF in normal rat knee can be prevented by etanercept, COX-inhibitors, and by inhibitors of the p38 kinase pathway LOSI G - Glutamatergic and GABAergic signaling to astrocytes: focus on entorhinal and temporal cortices during epileptic activities Losonczy Gy. - CLINICAL INVESTIGATION ON THE ROLE OF ADENOSINE TRIPHOSPHATE (ATP) IN AIRWAY DISEASES USING NON-INVASIVE METHODS Lostale F - PINOLINE AND MELATONIN PREVENT CHANGES IN MEMBRANE FLUIDITY IN THE LIVER DUE TO CARBON TETRACHLORIDE. Lostao MP - EFFECT OF TNFalpha ON SUGAR ABSORPTION IN CACO-2 CELLS Lotz C - Effects of acidosis and/or hypoxia on the activity of the p-glycoprotein in human colon carcinoma cells Lou-Bonafonte JM - KINETICS OF VOLUME CHANGE IN H2O2 INDUCED CELL DEATH IN QUAIL RED BLOOD CELLS. LOUCH W - Myocardial infarction in adult mice induces hypertrophy and congestive heart failure without reduced contraction of non-infarcted cardiomyocytes LOUCH WE - Reduced t-tubule density and less synchronous Ca2+ release in cardiomyocytes from rats with congestive heart failure Louch WE - Heart function is sustained in adult cardiac Serca2null mice with enhanced plasma membrane Ca2+ flux. LOUCH WE - Keeping the balance between sodium and calcium in cardiac disease   - Ryanodine receptor sensitivity determines Ca2+ wave velocity in cardiomyocytes   - Structural remodelling of failing cardiomyocytes and impairment of SERCA function consequences for dyssynchrony of Ca2+ release   - Variable t-tubule density and excitation-contraction coupling in rat atrial cardiomyocytes   - Alterations in potassium currents, AP shape, and resting membrane potential during heart failure   - The effect of -adrenergic stimulation on arrhythmogenic Ca2+ release in ventricular cardiomyocytes with reduced SERCA2 abundance. Louchami K. - HYPOTONICITY INDUCES INSULIN RELEASE BY OPENING VOLUME SENSITIVE ANION CHANNELS IN BRIN-BD11 B CELLS   - ALTERATION OF CALCIUM FLUXES AND CALCIUM-DEPENDENT INSULIN RELEASE IN PANCREATIC ISLETS FROM w3 FATTY ACID-DEPLETED RATS Louchami K. - HYPOTONICITY-INDUCED INSULIN RELEASE IN BRIN BD11 CELLS IS MEDIATED BY HYDROGEN PEROXIDE   - ROLES OF SGLT1, GLUT1 AND GLUT4 IN THE SECRETION OF GLUCOSE BY ACINAR PAROTID CELLS   - MODULATION BY LONG-CHAIN POLYUNSATURATED 3 AND 6 FATTY ACIDS OF THE METABOLIC SYNDROME IN RATS EXPOSED TO A FRUCTOSE-RICH DIET   - THE PRESENCE OF SGLT1 AND GLUT4 IN DUCTAL CELLS OF RAT AND HUMAN SALIVARY GLANDS   - HYPOTONCITY-INDUCED INSULIN RELEASE IS MEDIATED BY H2O2   - EXPRESSION OF THE ELECTROGENIC NA-HCO3-COTRANSPORTER NBCE1-A IN PANCREATIC ISLET CELLS   - INCREASED [CA2+]I AND SECRETORY RESPONSES TO CARBAMYLCHOLIN IN PANCREATIC ISLET CELLS IN LONG-CHAIN OMEGA-3 FATTY ACID-DEPLETED RATS   - IMPAIRED [CA2+]I AND SECRETORY RESPONSES TO OUABAIN IN PANCREATIC ISLET CELLS FROM RATS DEPLETED IN LONG-CHAIN POLYUNSATURATED 3 FATTY ACIDS Loudon A.S.I. - The tau mutation in mice and hamsters LOUHIVUORI L - Inhibition of glucose induced insulin secretion by orexin-A LOUHIVUORI L - Glutamate receptors in migrating neural progenitor cells Louis M. - CALCIUM ENTRY THROUGH TRPC1 CHANNELS INDUCES CALPAIN ACTIVATION AND CONTROLS MYOBLASTS MIGRATION   - TRPC1 REGULATES SKELETAL MYOBLASTS MIGRATION AND DIFFERENTIATION Lourdel S - Cl-/H+-exchange mediated by CLC proteins Loussouarn G. - Molecular mechanisms underlying kcnq1 voltage-dependency: the channel gate is locked closed by the S4-S5 linkers Lovas G - IDENTIFICATION OF THE CELL TYPES EXPRESSING DIFFERENT TGF-BETA PROTEINS FOLLOWING FOCAL ISCHEMIA IN THE RAT BRAIN   - THE EXPRESSION PATTERNS OF TGF BETA 1, 2 AND 3 AT DIFFERENT TIME POINTS FOLLOWING FOCAL BRAIN ISCHEMIA LOVDAHL C - The small GTPase Rac1 is required for smooth muscle force development   - Excitation and contraction of cardiac muscle and coronary arteries of normal and brain dead pigs LOVISOLO D - Calcium dependence of bFGF-mediated neurite growth in cultured parasympathetic neurons LOVISOLO D - FGF-2, calcium signals and the control of neurite growth in chick developing parasympathetic neurons   - FGF-2 and neurite outgrowth in cultured chick ciliary ganglion neurons: somatic versus neuritic signaling pathways   - The involvement of ERK and PI3K pathways in the neurotrophic effects of basic Fibroblast Growth Factor on cultured parasympathetic neurons Lovric M. - Hepatic and renal sat-1 in ethylene glycol-induced oxaluria in rats Loyens E. - EFFECTS OF SIMVASTATIN ON CELL VIABILITY AND H2O2-INDUCED OXIDATIVE INJURY IN OLN-93 OLIGODENDROGLIAL CELLS Loyens E. - Anticonvulsive effects of insulin-regulated aminopeptidase deletion in a pentylenetetrazol mouse seizure model are not mediated by the accumulation of somatostatin-14   - Decreased expression of vGLUT1 increases vulnerability to seizures   - INVESTIGATIONS INTO THE ROLE OF SOMATOSTATIN IN THE ANTICONVULSIVE EFFECTS OF INSULIN-REGULATED AMINOPEPTIDASE INHIBITORS   - INVOLVEMENT OF THE CYSTINE/GLUTAMATE ANTIPORTER IN HIPPOCAMPAL FUNCTIONING: IMPLICATIONS FOR SEIZURE SENSITIVITY   - ANTIDEPRESSANT-LIKE EFFECTS OF OXYTOCIN IN MICE SEEM DEPENDENT ON METABOLISATION BY INSULIN-REGULATED AMINOPEPTIDASE   - VGLUT2 HETEROZYGOUS MICE SHOW MORE SUSCEPTIBILITY TO CLONIC SEIZURES INDUCED BY PENTYLENETETRAZOL Lozano GM - CASPASE 3 ACTIVATION IN HUMAN SPERMATOZOA IN RESPONSE TO PROGESTERONE   - H2O2-INDUCED CASPASE 3 ACTIVATION IS DEPENDENT OF CALCIUM SIGNAL IN HUMAN SPERMATOZOA Lozano GM - A STUDY OF CALCIUM HOMEOSTASIS IN SPERMATOZOA FROM ASTHENOZOOSPERMIC PATIENTS Lozinsky I - Complex kinetics of P2X7-dependent single channel currents Lozova V. - Exploratory behaviour of stressed rats in the elevated alley Suok test under the quercetin administration Lozova V - Adiachrom influence on a behavior of rats subjected to the immobilization stress Lozovaya N - Opioids and cannabinoids control P2X nociceptors in mammalian sensory neurons Lpez Daniel Horacio - 2-HYDROXY ARACHIDONIC ACID (2OAA), A NEW NON STEROIDEAL ANTI-INFLAMMATORY DRUG Lpez Miguel - THYROID HORMONE THERMOGENESIS IS MEDIATED BY BROWN ADIPOSE TISSUE LTrujillo M - Interleukin-6 Regulates the Expression of Hypothalamic Neuropeptides Involved in Body Weight in a Gender and Age-Dependent Way Lu J - Brainbow: Combinatorial expression of fluorescent proteins to visualize neuronal circuits LU N - Role of integrins in maintaining tissue homeostasis: a11b1 integrin and fibroblast function LU B - Roles of the NALCN ion channel complex in neuronal excitability and its modulation by neurotransmitters Lu L. - Electrophysiological Properties of Human Atrial Fibroblasts from Patients in Sinus Rhythm and Atrial Fibrillation Lu X. - THE (PRO)RENIN RECEPTOR IS REQUIRED FOR VACUOLAR H+-ATPASE REGULATION IN COLLECTING DUCT CELLS Lu Z. - A role for urea in the regulation of ruminal pH Lubamba B. - CORRECTING EFFECT OF PHOSPHODIESTERASE 5 INHIBITORS ON CHLORIDE TRANSPORT IN CYSTIC FIBROSIS Lubics A - DISTRIBUTION OF PACAP AND ITS TYPE I RECEPTOR IN THE RAT KIDNEY Lubics A. - EFFECTS OF IN VIVO RENAL ISCHEMIA/REPERFUSION IN HETEROZYGOUS PACAP DEFICIENT MICE   - MICE DEFICIENT IN PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE (PACAP) SHOW INCREASED SUSCEPTIBILITY TO IN VIVO RENAL ISCHEMIA/REPERFUSION INJURY   - PRESENCE OF PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE (PACAP) IN THE HUMAN PLACENTA AND ITS EFFECTS ON CYTOTHROPHOBLAST CELLS   - PACAP-LIKE MOLECULES IN EARTHWORMS AND THEIR INFLUENCE ON THE BRAIN REGENERATION   - INVESTIGATION OF PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE IN HUMAN ANDROLOGICAL FLUID AND ITS EFFECT ON SPERM MOTILITY LUBKE J - Synapses on layer 4 excitatory neurons in the rat barrel cortex LUBKE JR - Fast spiking interneurons in layer 4 of rat barrel cortex   - Developmental changes in synaptic transmission between layer 4 spiny neurons of rat barrel cortex Lubkemeier I. - Functional connexin40 protein is mandatory for conduction of endothelium-dependent dilations in arterioles and blood pressure control   - The Connexin40 A96S Loss-of-Function mutation from a patient suffering from atrial fibrillation causes renin dependent hypertension in mice Lubomirov *L.T. - Effect of eNOS inhibition on subcellular localization of myosin phosphatase targeting subunit, MYPT1 in mouse brain vasculature Lubomirov L - Regulation of nuclear genes encoding mitochondrial proteins during skeletal muscle differentiation by cAMP responsive element binding protein 1 (CREB1) Lubomirov LT - Deletion of the myosin binding domain of caldesmon augments endothelium-dependent relaxation   - cAMP activates smooth muscle myosin phosphatase (SMPP-1M) through a PKA-dependent and PKA- independent mechanism LUBOMIROV L T - Signalling events involved in cyclic nucleotide mediated relaxation of murine gastric fundus (GF)   - Ca2+-independent monophosphorylation of MLC20 at Thr18 during cyclic nucleotide-mediated relaxation Lubomirov L. T. - Ileal smooth muscle contractile activity of neonatal mice is less sensitive to cAMP/PKA than to cGMP/PKG signaling   - Endothelium dependent modulation of phosphorylation of smooth muscle myosin phosphatase in brain vessels by the thromboxane A2 mimetic, U-46619 LUBRANO C - Safety and efficacy of genistein in osteopenic, postmenopausal women: a follow-up study LUBRANO LAVADERA M - Haptoglobin impairs the anti-atherosclerotic function of Apolipoprotein E Luc Snoeckx - Minimum standard and learning outcomes required by the Bologna process Lucas A - EFFECT OF PHOTOPERIOD ON INCUBATION TIME, SURVIVAL AND GROWTH OF NOTHOBRANCHIUS KORTHAUSAE   - CHARACTERIZATION OF NOTHOBRANCHIUS KORTHAUSAE AS A MODEL FOR STUDYING AGING PHYSIOLOGY LUCAS J - Increased neocortical excitability and loss of synaptic plasticity in NPC1-knockout tissue in vitro Lucas ML - Lack of effect in vivo of K+-channel modulators of fluid absorption after Escherichia coli enterotoxin (STa) challenge. LUCCHETTI C - May the warning auditory-visual neurons help the monkey to play the piano?   - Neglect sindrome for aversive and pleasant stimuli in a macaque monkey with PEEF lesion Luchka I. - Influence of carbohydrates on the methanogenesis in the cattle rumen Lucian Mocan - SINGLE WALLED CARBON NANOTUBES FUNCTIONALIZED WITH SINGLE STRAND DNA EFFECTS OVER REDOX BALANCE. AN IN VITRO AND IN VIVO STUDY Luciana Dumitriu Irina - Involvement of the intrapulmonary renin angiotensin system in the development of allergic lung disease   - The angiotensins vasomotor effects on rat renal arteries   - Nitric oxide involvement on apelin effects on bronchial reactivity LUCIANI G - Muscular effects of orexin A on the mouse duodenum: mechanical and electrophysiological studies   - Electrophysiological characterization of neuronal and smooth muscle differentiation of human stem cell from adipose tissue LUCINI D - Cardiovascular responses to standing at the end of 35-day bed rest in humans Lucini Daniela - Maximal oxygen consumption in upright and supine posture at the end of prolonged bed rest in humans Luckenbach JA - Fish as a Model to Study Metabolic Influences on Puberty Onset Luckhoff A - Who is the keeper of the gate? - Single-channel properties after reciprocal exchange of the pore in the cation channels TRPM2 and TRPM8 LUCONI M - Electrophysiological characterization of neuronal and smooth muscle differentiation of human stem cell from adipose tissue Luculescu Maria - Cardioprotection at reperfusion: uncoupling effects of diazoxide and cyclosporine a on infarct size and functional recovery in isolated rat hearts Luddens H - The anesthetic ketamine modulates GABAA -receptors in the cerebellum LUDDENS H - Heterogeneity of responses to GABA and other agonists in recombinant receptor subtypes Ludes A - Endogenous ion channels in bone-marrow derived mast cells from mice   - Calcium signals in murine intestinal lymphocytes LUDVIGSEN S - Cerebellar neuronal hypoxia tolerance in a diving bird, the common eider duck (Somateria mollissima) Ludwig *F.T. - NHE1 generates pH-nanoenvironments at focal adhesions Ludwig A - Deletion of the cardiac pacemaker channel HCN4 in adult mice results in sinus node dysfunction with arrhythmia and repetitive asystolic phases Ludwig MG - Regulation of ion transport by the proton-activated receptor OGR1   - The ovarian cancer G-protein coupled receptor 1 (OGR1) modulates the activity of the vacuolar H+ - ATPase and Na+ /H+ exchangers   - Regulation of ion transport by the proton-activated receptor OGR1 Ludwig Y - Separate routes for ions and macromolecules through nuclear pore complexes   - Evidence for the existence of two separate pathways in the nuclear pore complex   - Genome of herpes simplex virus type-1 translocates through the nuclear pore as a condensed, rod-like structure   - Specific nuclear pore clusters mediate glucocorticoid induced import and export processes Ludwig A. - Analysis of pacemaker currents in intralaminar and sensory thalamic nuclei Ludwig F. - Expression and activity of the calcium-activated potassium channels KCa3.1 in pancreatic stellate cells   - Is the antimetastatic effect of NHE1-inhibition on melanoma metastasis target organ-specific? Ludwig F.T. - pH-taxis: Directional tumor cell migration along pH-gradients Ludwig M. - Evaluation of Current Components in murine CD117(pos) AT2R(pos) Bone Marrow Stem Cells Ludwig Steppan Dominik - ROLE OF BLOOD PRESSURE TO MEDIATE THE INFLUENCE OF SALT INTAKE ON RENIN EXPRESSION IN AT1A RECEPTOR DEFICIENT KIDNEYS Lueg G. - N-octanoyl-dopamine, NOD, is an agonist at the capsaicin receptor TRPV1 that improves renal function in an ischemia induced acute renal failure model Luft FC - Evidence against direct coupling between single L-type Cav1.2 Ca2+ channels and RyRs to generate Ca2+ sparks in arterial vascular smooth muscle cells (VSMC).   - Adiponectin is a novel potent humoral vasodilator LUFT F - Systemic peripheral artery relaxation by KCNQ channel openers and hydrogen sulphide Luft F. C. - Novel interaction between P450 eicosanoidsandendothelial nitric oxide in thecontrol arterial tone in mice Luheshi G. N. - Leptin modulates neuroinflammation and neutrophil recruitment into the brain of mice during severe LPS-induced systemic inflammation   - Spatiotemporal activation of the transcription factor NF-IL6 in the rat brain during systemic inflammation Luhmann H - Intracellular signalling cascades involved in activity-dependent synaptic secretion of neurotrophins Luhmann HJ - Statin-induced nitric oxide production prevents C-reactive protein dependent disruption of the blood brain barrier   - Hypoosmolar conditions enhance epileptiform activity and reduce extracellular volume fraction in the CA3 region of the immature rat hippocampus   - Chloride Regulation in Cajal-Retzius Cells of the Neonatal Rat Cerebral Cortex Luhmann H. - Use dependent shifts in intracellular Cl- alter GABAergicactions in identified neurons of the immature neocortex   - Sunday, March 22, Audimax, Poster Area APoster SessionYoung Investigator Award (Poster)Cardiovascular systemModerators: K. Brixius (Kln)U. Decking (Dsseldorf) Protein based nanoparticles for the efficient delivery of genes into brain endothelial cells   - GABAergic networks in the developing cerebral cortex are activated by taurine LUIGETTI M - nAChRs in Amyotrophic Lateral Sclerosis Luigi De Riu Pier - ENCODING OF VIBRISSAE MOVEMENT DIRECTION BY MESENCEPHALIC TRIGEMINAL NEURONS   - EVOKED RESPONSES OF TRIGEMINAL MESENCEPHALIC NEURONS TO ARTIFICIAL WHISKING IN THE RAT   - SENSORY INNERVATION OF THE WHISKER PAD BY MESENCEPHALIC TRIGEMINAL NEURONS Luik S. - Participation of leukotriene C4 in the regulation of suicidal erythrocyte death Luin Elisa - The role of reactive oxygen species on proliferation and Ca2+ signalling of skeletal muscle cells during IN VITRO ageing LUIN E - Neural agrin enhances the regenerative potential of aged human skeletal myoblasts   - Effects of hydrogen peroxide (H2O2) on electrical membrane properties of skeletal muscle myotubes   - Age-dependent effect of Hydrogen peroxide (H2O2) on skeletal muscle cells and neuromuscular transmission   - Adenosine-mediated modulation of the embryonic isoformof the muscle nicotinic acetylcholine receptor Luiten P. G. M. - HEALTHY VS. PATHOLOGICAL AGING OF THE BRAIN: ROLE OF PREVENTION Lujan R - Ionic mechanisms controlling dampened neuronal oscillations in the nucleus reticularis thalami Lujan R - CSP-ALPHA IS REQUIRED TO PREFERENTIALLY PREVENT NEURODEGENERATION OF GABAERGIC SYNAPSES IN CULTURED HIPPOCAMPAL NEURONS Lujan R. - L-type calcium channels control age-dependent desensitization and cocaine-induced plasticity ofD2-autoreceptor function in substantia nigra dopamine midbrain neurons Luka B - Hypercapnic ventilatory responses in patients with brainstem lesions Lukacs B - EFFECT OF MAUROCALCINE ON THE SKELETAL TYPE RYANODINE RECEPTOR   - ALTERED MODULATION OF THE SKELETAL TYPE RYANODINE RECEPTOR / CALCIUM RELEASE CHANNEL BY ATP IN MALIGNANT HYPERTHERMIA Lukács P. - Evidence for a rotational movement of the domain IV S6 segment of the voltage-gated Na channel during fast inactivation Lukacsi E - MULTIPLE IMMUNOFLUORESCENT LABELLING AND COMBINED CONFOCAL AND ELECTRON MICROSCOPIC METHODS IN STUDYING THE FUNCTION AND SYNTHESIS OF ENDOMORPHIN-2. Lukashev D - The fibrous sheath protein TSGA10 prevents nuclear accumulation of testis-specific hypoxia-inducible factor (HIF)-1a I.1 Lukashov D. - Zinc content in stomach mucosa cells of cold stressed animals Lukaszuk A. - RENAL VASOCONSTRICTOR AND PRESSOR RESPONSES TO ANGIOTENSIN PEPTIDES IN WILD TYPE, AT2 RECEPTOR AND IRAP KNOCK OUT MICE   - [3H]AL-11, A new stable and selective ligand for the IRAP/AT4 receptor in both membranes and intact cells   - PRESSOR AND RENAL EFFECTS OF ANGIOTENSIN A Lukic I.K. - Leukocyte rolling in vivo is regulated by RAGE Lukowski R - cGMP signals through cGMP- and cAMP-kinase in murine aorta Lukstina Zane - BILATERAL DIFFERENCE IN SUPERFICIAL AND DEEP FEMORAL ARTERY BLOOD FLOW Lukyanetz OO - Features of lipid droplets ultrastructure in rat adrenocortical cells are connected with attributes of accelerated steroidogenesis and also are supervised through calcium dependent mechanisms Luleci Nurettin - COMPARISON OF MELATONIN AND OZONE IN THE PREVENTION OF REPERFUSION INJURY FOLLOWING UNILATERAL TESTICULAR TORSION: AN EXPERIMENTAL STUDY IN RATS Lullmann-Rauch R. - Renal pathophysiology in mice deficient for the tetraspaninCD63/LIMP-1 LULY P - Thyroid hormone inhibition of IGF-1-mediated glucose uptake in myoblasts L-6 through interaction with the alphaVbeta3 integrin   - Nongenomic effects of thyroid hormones: An update Luna C - NEURAL BASIS OF SENSATIONS IN THE INTACT AND THE INJURED CORNEA Luna Sanchez M - CoQ Biosynthesis and Genotype-Phenotype Relationships in New Mouse Models of Primary CoQ Deficiency Luna-Sanchez M - CoQ deficiency: molecular and pathophysiological consequences.   - Unstable Mitochondrial Supercomplexes Contributes to the Pathophysiology of CoQ Deficiency Syndrome   - Melatonin modulation of the NF-kappaB signaling pathway in sepsis.   - BENEFICIAL EFFECTS OF TOPIC MELATONIN ADMINISTRATION AGAINST MITOCHONDRIAL DAMAGE DURING RADIOTHERAPY-INDUCED MUCOSITIS LUND J - High intensity interval training normalizes cardiac energetics and ventricular function in diet-induced obese mice LUND S - Regulation of the hepatic glycerol channel aquaporin-9 in starved rats is gender specific   - Maternal protein restriction before pregnancy reduces offspring early body mass and affects glucose metabolism in C57BL/6JBom mice Lund S.F. - Novel roles of NHE1 in motility of serum-starved MCF7 breast cancer cells expressing truncated ErbB2 (?NErbB2) LUNDBERG J - LPS and PGN stimulates mucus secretion in colon   - Dietary nitrate increases intraduodenal NO and blood flow and reduces inflammation caused by non-steroidal anti-inflammatory drugs   - Oral bacteria regulate gastric mucosal defense via bioactivation of dietary nitrate Lundblad James - Familial hypocalciuric hypercalcemia: Reduced affinity of calcium sensing-receptor heterodimers underlies impaired receptor function Lundby A. - KCNQ1 mutation Q147R is associated with atrial fibrillation and prolonged QT-interval Lundby C - WHY IS MAXIMAL CARDIAC OUTPUT REDUCED IN CHRONIC HYPOXIA? LUNDBY A - The Transient Outward Potassium Channel Activator NS5806 exerts Differential Effect in Canine Atrial and Ventricular Cells Lundbye-Jensen J - The role of plastic changes in the motor cortex and spinal cord for motor learning Lunde IG - PPAR is a link between muscle activity and a slow/oxidative muscle phenotype LUNDE P - Contribution of skeletal muscle to cytokine production in heart failure LUNDE PK - Fatigue in slow twitch skeletal muscle following a dynamic exercise protocol Lunde PK - The Role of SERCA2 in Skeletal Muscle Function LUNDE IG - Cardiac O-GlcNAc signaling is increased in hypertrophic and failing hearts   - Isoform-specific activation of NFAT transcription factors in ANGII and NA-stimulated hypertrophic cardiomyocytes LUNDE IG - Syndecan-4 regulates NFAT activation in cardiac fibroblasts following stretch Lunden L.K. - Electrophysiological characterization of a loss-of-function mutation of Nav1.8 in a patient with erythromelalgia LUNDERVOLD A - Assessment of structural and functional connectivity of the human brain using multimodal MRI and graph theory Lundgaard I - Neurotransmitter signalling to oligodendrocytes and their precursors in health and disease LUNDGREN P - Millisecond substance exposure on HEK-293 cells expressing several GABA-A receptor subtypes using patch-clamp in DynaflowTM system   - Mechanisms for neurosteroid action on cognitive function from receptors to human disorders   - Neurosteroids 3,20 (R/S)-pregnandiols decrease offset rate of the GABA-site activation at the recombinant GABAA receptor Luneburg N - Identification of a novel enzyme degrading the cardiovascular risk marker symmetric dimethylarginine(SDMA) LUNGHI L - NADPH oxidase involvement in SRB1 modulation by lipid peroxidation   - Stability and Permeability study of a Zidovudine-Bile Acid Prodrug   - Beta-methasone effects on trophoblast connexin expression LUNNEMANN M - Defective jejunal and colonic salt absorption and altered Na+/H+ exchanger 3 (NHE3) activity in NHE regulatory factor 1 (NHERF1) adaptor protein deficient mice Lunnemann M. - Preserved abundance but functional dysregulation of Na+/H+ exchanger isoform NHE3 in the small and large intestine in CD45RBhigh transfer colitis mice with diarrhea LUO J - Increased neocortical excitability and loss of synaptic plasticity in NPC1-knockout tissue in vitro LUO M - NHERF2 PDZ-adapter determines the membrane raft association of the apical Na+/H+ exchanger NHE3 in murine small intestine Luo M. - Interleukin-1ß-induced decrease of NHE3 interacting protein PDZK1, as well as sh-RNA-mediated PDZK1 knockdown, is associated with NHE3 dysfunction in the colonic epithelial cell line Caco-2bbe Luomala M - The use of a cooling vest during exercise in warm condition improves cycling performance ... with no risk of getting high level of urinary testosterone! LUOMALA M - The use of a cooling vest during exercise in warm condition delays the appearance of fatigue and improves cycling performance Lupant A. - DISTRIBUTION OF MECHANICAL ADVANTAGE AND RESPIRATORY ACTIVITY IN THE LEVATOR COSTAE MUSCLE Lupescu *A. - Carbon monoxide stimulates Ca2+ entry into erythrocytes triggering programmed cell death Lupescu A - Mitochondria-independent death receptor mediated cytosolic acidification during apoptosis of T cells   - Impaired mast cell activation in mice lacking the Serum- and Glucocorticoid-inducible Kinase SGK1   - Inhibition of Na+/H+ Exchanger Activity by Parvovirus B19 Protein NS1 Lupescu A. - Withaferin A induced erythrocyte membrane phospholipid asymmetry   - Parvovirus B19 protein NS1 inhibits Na+/H+ exchanger   - Effect of honokiol on erythrocytes   - Apigenin-induced suicidal erythrocyte death LUPIDI G - Thymoquinone induces apoptosis in human glioblastoma cell lines LUPPI M - Heart rate variability is modulated by neurons within the rostro ventromedial medulla   - Neurons within the rostro ventromedial medulla control cutaneous vasomotion   - Torpor-like state induction by inhibition of the rostral ventromedial medulla in the free behaving rat   - Activation of muscarinic receptors within the lateral hypothalamus increases cardiovascular and thermogenetic sympathetic outflow LUPPI P-H - Hypothalamic and brainstem GABAergic neurons controlling paradoxical (REM) sleep Luque ME - ESTROGENIC EFFECT OF 17 BETA-ESTRADIOL ON MEMBRANE POTENTIAL IN AORTIC SMOOTH MUSCLE CELLS OF RATS Lurbke A - CFTR regulates the paracelluler permeability in bronchial epithelium   - Analysis of CFTR clustering by Quantum Dot techniques Lurie Robert H. - Serpin in cancer: Maspin as a paradigm Luscher HR - Combined voltage and calcium imaging in vitro and in vivo reveals subthreshold and suprathreshold dynamics of mouse barrel cortex LUSSIGNOLI D - Changes in contractile properties induced by posttetanic potentiation of two different human leg muscles Lutfi Erdem Tamer - THE EFFECTS OF RADIOTHERAPY AND CHEMOTHERAPY ON ROOT DEVELOPMENT: REPORT OF 2 CASES Lutge C - Philosophy and physiology Luthi A - Ionic mechanisms controlling dampened neuronal oscillations in the nucleus reticularis thalami Luthje L - AT1 receptor blockade ameliorates pulmonary and extrapulmonary manifestations of elastase-induced lung emphysema in mice Lutsenko S - Effects of sequence variation on plasma membrane localization of Wilson Disease Protein expressed in Xenopus laevis oocytes Lutz H - Enhanced erythro-phagocytosis in polycytemic mice overexpressing erythropoietin Lutz Thomas Alexander - REDUCED BODY WEIGHT IN HYPOXIC RATS AND MOUNTAINEERS LUTZ B - Cannabinoid-CB1 receptor in mouse central amygdala is involved in depolarization-induced suppression of excitation and fear behavior Lutz H. - ANALYSIS OF IMIDAZOLINE RECEPTORS IN THE REGULATION OF GASTRIC MOTILITY IN MICE Lutz R. - Electrophysiological Properties of Human Atrial Fibroblasts from Patients in Sinus Rhythm and Atrial Fibrillation Lutz S. - Cellular changes induced by hypoxia in fibroblast and myoblasts Lutz W. - The proinflammatory cytokine TNF dose-dependently inhibits spreading depolarization (SD) in adult rat cortex Lütz W. - The proinflammatory cytokine TNFα inhibits cortical spreading depolarization (CSD) in adult rat cortex via neuronal TNF receptor 2 LUTZE P - Overexpression of cytosolic renin improves survival of cardiac cells after exposure to ischemia-associated conditions Lutze P. - Monday, March 23, Audimax, Poster Area EPoster Session: Stem and progenitor cells and transcription factorsModerators: B. Fleischmann (Bonn)A. Sachinidis (Kln) Cytosolic exon(29)renin protects H9c2 cardiomyoblasts from necrosis induced by oxidative stress via beneficial effects on mitochondrial functions Lutz-Meindl U - Ultrastructural Characterisation of Apoptosis in the Microglial Cell Line, BV-2, after UV-Irradiation   - Cholinergic mechanisms modulate cell differentiation in the green alga, Micrasterias denticulata Lutz-Meindl Ursula - Apoptosis without karyorrhexis in microglia Luu V.-D. - Onconeuronal cerebellar degeneration-related antigen Cdr2 is strongly expressed in papillary renal cell carcinoma and leads to attenuated hypoxic response LUUKKO K - Imaging millimeters thick tissues using confocal microscopy LUX RL - Dynamic analysis of SA nodal cells action potential sequences and their autonomic modulation by means of a newly developed software Luzhinskaya A - Neurotransmitter signalling to oligodendrocytes and their precursors in health and disease LUZI L - Resveratrol promotes myogenesis and hypertrophy in murine myoblasts   - Effects of betaine on myogenesis in murine myoblasts   - The effects of DNA methylation during muscle differentiation in mouse myoblasts   - Insulin-mimetic action of conglutin- in mouse myoblasts   - Improved resistance to exercise in mice treated with metformin Lyaschenko T. - Bombesin influence on bile lipid composition in rat Lybaert L. - KATP CHANNELS IN HUMAN PLACENTA, POSSIBLE IMPLICATION IN hPL AND hCG RELEASE? Lybaert P. - EVIDENCE FOR KATP CHANNELS EXPRESSION IN THE EPIDIDYMIS FROM VARIOUS MAMMALIAN SPECIES   - KATP CHANNELS IN SPERMATOZOA: EXPRESSION IN DIFFERENT SPECIES AND INVOLVEMENT IN CALCIUM INFLUX   - ACROSOME DETECTION AND REACTION TO CALCIUM IONOPHORE CHALLENGE IN MOUSE SPERMATOZOA: METHODOLOGICAL CONSIDERATIONS   - EXPRESSION AND LOCALIZATION OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR IN THE ENDOCRINE PANCREAS.   - EXPRESSION OF THE ELECTROGENIC NA-HCO3-COTRANSPORTER NBCE1-A IN PANCREATIC ISLET CELLS   - THE PRESENCE OF SGLT1 AND GLUT4 IN DUCTAL CELLS OF RAT AND HUMAN SALIVARY GLANDS   - EXPRESSION OF GLUT-2 AND THE ELECTROGENIC NA+-HCO3COTRANSPORTER NBCE1 IN HUMAN ENDOCRINE PANCREAS Lye S.J. - The effect of oxygen on placental connexins 43 and 46 and its contribution to preeclampsia LYONS D - A Hypothalamo-Cortical Circuit for Recruiting Arousal to Food Intake LYRENAS S - Plasma vasopressin, oxytocin, estradiol, and progesterone related to water and sodium excretion in normal pregnancy and gestational hypertension Lyrmann H. - Quantitative analysis of calcium dependent migration in human cytotoxic T cells Lysenko N - Kva2 subunits carry a large part of the Kv current of rat cerebral artery smooth muscle cells Lysenko N. - Unusual role of Kv2 channels in rat posterior cerebral small arteries Lyssenko V - Common genetic variants of the human L-type calcium channel Cav1.3 associate with impaired insulin secretion