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Acta Physiologica Congress

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Acta Physiologica 2006; Volume 186, Supplement 650
Joint Meeting of The German Society of Physiology and The Federation of European Physiological Societies 2006
3/26/2006-3/29/2006
Ludwig-Maximilians-University, Munich


EFFECTS OF GREEN TEA ON OXIDATIVE STRESS IN STREPTOZOTOCININDUCED DIABETIC RATS
Abstract number: PW10P-6

Tas1,2 S, Sarandol1,2 E, Dirican1,2 M

1Department of Biology, Uludag University, Science and Literature Faculty, Bursa, TURKEY
2Department of Biochemistry, Uludag University Medical Faculty, Bursa TURKEY

The purpose of this study was to determine the effects of green tea on lipid profile, oxidant and antioxidant status in streptozotocin-induced diabetic rats. Male Wistar rats were randomly divided into four groups; control (C), control + green tea (C + GT), diabet (D), diabet + green tea (D + GT). Serum insulin level was significantly increased in the D + GTgroup; serum lipid, and plasma and tissue malondialdehyde levels were significantly reduced in the D + GT groups. Oxidizability of apolipoprotein B-containing lipoprotein fraction was found to be significantly reduced in the D + GT group. Paraoxonase activity was significantly reduced in the D group and increased in the D + GT group. We conclude that green tea exerts beneficial effects on glucose metabolism, has hypolipidemic and antioxidative effects and may slow down the progression of atherogenesis by playing role in protecting lipoproteins against oxidation.

To cite this abstract, please use the following information:
Acta Physiologica 2006; Volume 186, Supplement 650 :PW10P-6

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