The most important function of the pylorus (P) is its discriminating function - ability to delay evacuationg of the big parts of solid food from stomach (S). For today our knowledges about the role of ramus pyloricus nervi vagi (RPNV) which innervates P in discriminating function of P are limited. The aim of the study was to investigate the influence of transection of RPNV on emptying on small and big corpuscles from S. The study was done in chronical experiments on dogs with fistulas of fundus of S and duodenum. The 4 dogs were with intact nervous system (INS). The 3 dogs were after operation of cutting of RPNV. 600 small (1x1x1 mm) and 300 big (3x3x4 mm) rubber corpuscles were added into the 100 gram of bread. During experiment the duodenal fistula was opened. Rubber corpuscles leave the stomach regularly with chime that is why amount of corpuscles shows the part of food which left the stomach for each 30 minutes. It was established that in dogs with INS each 30 min 16% of small corpuscles and 5,9% of big corpuscles from their amount in S leaved S. In the ending phase of digestion big corpuscles leaved S without obstacles. The cutting of RPNV lead to the disturbance of this proportion. During first and second 30 min of the emptying 40–50% of small and big corpuscles leaved S. In the third and fourth half an hour they lefting decreased to the 12–14% from general amount.