Electrical fields can affect carrier-mediated transport by modulating ion binding or conformational transitions. Various forms of perturbation analysis exploit these phenomena to obtain information about individual rate constants of complex kinetic mechanisms. Herein, oscillatory voltage stimuli can produce potentially large effects that are often more informative than pre- steady state current measurements (Horn LW, BiophysJ 64:281,1993). However, the corresponding mathematical models have no general analytical solution, and previous reports were limited to tractable special cases. Here, we used numerical methods to study the effect of oscillatory voltage on electroneutral transport by a general four-state carrier (i.e. of an uncharged substrate) and six- state carriers (symport of opposite charges or antiport of similar charges) in which all individual reaction steps were potentially voltage sensitive (Läuger P, PhysiolRev 67(4):1296). Sensitivity of steady-state flux to various parameters (e.g. stimulus frequency and amplitude, relative electrical distances for binding or reorientation) was studied systematically. The results were verified by different algorithms, and identified several scenarios where oscillatory voltage effects are particularly useful to discriminate between competing kinetic models. The approach is feasible in Xenopus oocytes and mammalian cells and may be helpful to elucidate the largely unknown microscopic kinetics of electroneutral transporters.