Adjustment of grip forces is required to maintain a slipping object in hand. The aim of the study was to test associative learning of grip force adjustment using the classical conditioning approach. A special grip rod with 200 strange gauges equally distributed on 50 cm2 was developed. The rod was moved unexpectedly in horizontal direction with different load forces. Subjects were asked to hold the rod in its initial position with a three finger precision grip against varying load forces. Object slippage was provoked by liquid soap on the rod, resulting in a reduction of the friction between finger tips and rod. The unconditioned stimulus (US) consisted of a steplike pull/push load change up to 6N for 1s each. The conditioning stimulus (CS) was a 1000 Hz tone preceding the US by 400ms. Biomechanical data (grip-, load force) as well as electrophysiological data (m. thenar, m. interossius1, m. extensor digitorum communis, m. flexor carpi radialis) were measured. Preliminary results show that subjects react in US-alone trials with an increase of grip forces 165 ms after load perturbation. During paired trials subjects established conditioned responses by increasing the grip forces 130 ms before load perturbation. These results show that grip forces in healthy subjects can be conditioned in a classical conditioning paradigm.