Readme file
SERIES C
 Applied Statistics
A model of toxoplasmosis incidence in the UK: evidence synthesis
and consistency of evidence, by N. J. Welton and A. E. Ades
Journal of the Royal Statistical Society,
Series C, Applied Statistics, Volume
54 (2005) part 1, 385 - 404
DATA-SET: toxo_web.txt (Tab-Delimited text file, 23 columns, first
row labels)
NB The data all come from published sources. See the main text for
cited references.
Columns
obs = observation number
r = number of IgG positives for seroprevalence data
n = total number in sample for seroprevalence data
r.sc = number of sero-conversions for seroconversion data
n.sc = total person-years exposure observed for seroconversion data
r.igm = number of IgM positives for IgM data
n.igm = total number at risk (IgG negatives plus IgM positives) for
IgM data
region = region of seroprevalence, seroconversion or IgM data point
1 Inner London (E) 7 Midlands
2 Inner London (N) 8 South Yorkshire
3 Inner London (W) 9 Glasgow
4 Outer London (N) 10 Scotland Central
5 Non-Metropolitan (SE) 11 Inverness
6 East Anglia 12 Wales and West
time = observation time interval for sero-conversion and IgM data
1 1920-39 5 1970-79
2 1940-49 6 1980-89
3 1950-59 7 1990-present
4 1960-69
s[,a,t] = exposure in age group a and time interval t for sero-prevalence
data
a=1 0-14 a=2 15+
Note the final 3 rows are non-UK paired seroconversion/IgM data
PROGRAMS: The models were fitted using WinBUGS 1.4 (see comments in
individual files)
toxo_rbyt.mod is a text file with the code for Model III (regionxtime
interaction)
toxo_rbyt.dat is a text file with the data in two parts, a list and
an array (s)
to be read into WinBUGS
toxo_rbyt.ini is a text file containing two sets of initial values
toxo_rbyt_5077.dat is as above but excluding outliers 50 and 77
toxo_rbyt_5077.ini is as above but excluding outliers 50 and 77
WinBUGS .odc files are available at the above web site.
CONTACT:
Nicky Welton
MRC Health Services Research Collaboration
Department of Social Medicine
Canynge Hall
University of Bristol
Whiteladies Road
Bristol
BS8 2PR
UK
E-mail: Nicky.Welton@bristol.ac.uk
WEB-SITE: http://www.hsrc.ac.uk/Current_research/research_programmes/mpes.htm
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