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Readme file
SERIES
C
 Applied
Statistics
The assessment of tumour response to treatment, by
E. Demidenko
Journal of the Royal Statistical Society, Series
C, Applied Statistics, Volume 55
(2006), 365 - 377
The following is the description of software and data sets that were used
in the paper.
The S-Plus function synerg plots all graphs, computes estimates and table
results (specifically, version S-Plus 6.1 was used). Parameter job controls
specific computations. To download the function, issue source("c:\\projects\\synerg\\synerg.s"),
assuming that synerg.s is saved in the directory c:\projects\synerg\
The data files with tumour volume of four groups of rats are
c:\\projects\\synerg\\contrtum.txt
c:\\projects\\synerg\\pdtum.txt
c:\\projects\\synerg\\contrps.txt
c:\\projects\\synerg\\pdtps.txt
Only pdtum data are used as a treatment group in this paper.
More information about cancer experiments and photodynamic therapy can
be found in the following references.
Pogue, B. W., O'Hara, J. A., Demidenko, E., Wilmot, C. M., Goodwin, I.
A., Chen, B., Swartz, H.M. and Hasan T. (2003) Photodynamic therapy with
verteporfin in the radiation-induced fibrosarcoma-1 tumor causes enhanced
radiation sensitivity. Cancer Research, 63, 1025 - 1033.
Chen, B., Pogue, B. W., Zhou, X., O’Hara, J. A., Solban, N., Demidenko,
E., Hoopes, P. J. and Hasan T. (2005) Effect of tumor host microenvironment
on photodynamic therapy in rat prostate tumor model. Clinical Cancer Research,
11, 720 - 727.
Eugene Demidenko
Section of Biostatistics and Epidemiology
Dartmouth Medical School
Hanover
NH 03755
USA
E-mail: eugened@dartmouth.edu Datasets (Demidenko.zip,
size - 9KB) |
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Applied
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