Part I: Evidence-based medicine, randomised trials, and systematic reviews

1 Is evidence-based medicine still an option?
Neville W Goodman

2 Why do we need large randomised trials in anaesthesia and analgesia?
Paul S Myles

3 Why do we need systematic reviews in anaesthesia and analgesia?
R Andrew Moore

Part II: Systematic reviews in anaesthesia and analgesia

4 Acute pain
Henry J McQuay

5 Peripheral treatment of postoperative pain
Steen Møiniche, Jørgen B Dahl

6 Epidural analgesia for labour and delivery
Stephen Halpern, Barbara Leighton

7 Intravenous fluids for resuscitation
Peter T-L Choi

8 Postoperative nausea and vomiting
Martin R Tramèr

9 Propofol for anaesthesia and sedation
Bernhard Walder, Martin R Tramèr

10 Preventing central venous catheter related complications
Mehrengise K Cooper, Adrienne G Randolph

Part III: Dissemination, implementation, and research agenda

11 The Cochrane Collaboration — what is it about?
Tom Pedersen

12 Cost effectiveness of anaesthesia and analgesia
Ceri J Phillips

13 From evidence to implementation
Anna Lee, Tony Gin

14 Postoperative epidural analgesia and outcome — a research agenda
Kathrine Holte, Henrik Kehlet

Index

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