Subject Index
Coagulation Factors and Inhibitors
Fibrinolysis, fibrinogen, fibrin
Haemorrhagic Disorders
Invited
Other
Platelets
Thrombotic Disorders and antithrombotic therapy
Vascular Biology
Platelets
Animal and experimental models
Biochemistry and signal transduction
Inherited and acquired platelet disorders
Integrins and other adhesive proteins
Interaction with other cells
Megakaryocytes and thrombopoiesis
Other blood cells
Other glycoproteins
Other platelets
Physiology and pharmacology
Platelet activation markers
Platelet (function) tests
Procoagulant and fibrinolytic activity
Receptors for primary agonists
Secretion and protein trafficking
Structural biology and drug design
aIIbb3 integrin activation mechanisms – switchblade or scissors?
Hantgan R. R., Mallett T. C., Lyles D. S., Weisel J. W., Rocco M.
b3 integrin haplotype influences gene regulation
Payne K., Bray P. F., Grant P. J., Carter A. M.
b3-integrin deficiency and antibody-mediated b3-integrin inhibition have paradoxical effects on murine smooth muscle cell proliferation and the development of intimal hyperplasia after vascular injury
Smyth S. S., Thomas C. V., Hu Y., Reis E. D.
A new gene structure of disintegrin family: a subunit of dimeric disintegrin has short coding region
Morita T., Okuda D., Koike H.
A novel role for cytosolic calcium in down-regulating integrin aIIbb3 activation and platelet adhesiveness
Kulkarni S., Jackson S. P.
A role for the thiol isomerase activity of a IIbb 3 in receptor clustering
Robinson A., O'Neill S., Moran N.
Acquired platelet dysfunction with eosinophilia in children: A tropical disease present in Venezuela
Ruiz-Sáez A., Nuñez L., Feijoo R., Certad G., Arenas A., Rodriguez L., Ferrara R., Jimenez R., Bosch N.
Activation of the platelet integrin aIIbb3 by thermodynamic modulation of transmembrane helix associations
Bennett J., Li R., Vilaire G., Gratkowski H., Mitra N., Li W., Lear J. D., DeGrado W. F.
Analysis of Arg-Gly-Asp contact sites in the av subunit of integrin avb3 employing single amino acid mutations
Honda S., Tomiyama Y., Kashiwagi H., Kiyoi T., Kato H., Kosugi S., Shiraga M., Kurata Y., Matsuzawa Y.
Anti-CD63 monoclonal antibodies inhibit platelet spreading on immobilized fibrinogen
Israels S. J., McMillan-Ward E. M.
Biochemical, immunologic and computer-modeling evidence localizing the mAb 7E3 Epitope on aIIbb3
Artoni A., Li J. H., Mitchell W. B., Ruan J., Coller B. S., French D. L.
Calcium- and integrin-binding (CIB) protein is required for platelet spreading on immobilized fibrinogen: functional association of CIB with GPIIb/IIIa
Naik M. U., Naik U. P.
CD84 signaling is a novel platelet stimulatory mechanism that occurs during platelet aggregation
Nanda N., Bao M., Clauser K., Phillips D. R.
Characterization and preliminary crystallographic studies of EMS16, an antagonist of collagen receptor (GPIa/IIa) from the venom of Echis multisquamatus
Okuda D., Horii K., Mizuno H., Morita T.
Comparison of the binding character of triflavin on resting and activated aIIbb3 integrin in human platelets by electron microscopy
Fong T. H., Hsiao G., Sheu J. R.
Demonstration of activation of integrin aIIbb3 by inside-out signaling in a megakaryocytic cell line, CMK
Kashiwagi H., Tomiyama Y., Shiraga M., Honda S., Kosugi S., Kiyoi T., Kato H., Kurata Y., Matsuzawa Y.
Effect of cellular and receptor activation on the extent of integrin alphaIIb beta3 internalization
Schober J. M., Lam S. C. T., Wencel-Drake J. D.
Frequency of platelet glycoproteins alpha2807T and GPIbalpha Kozak polymorphisms in central retinal vein occlusion
Regina S., Arsene S., Delahousse B., Maakaroun A., Gruel Y.
Functional modulation of platelet aIIbb3 by its endogenous thiol isomerase activity
Walsh G., Moran N., O'Neill S.
Glycoprotein Ib and integrin a IIbb 3 contribute to GPVI-dependent vWF-collagen induced thrombus formation under flow
Kuijpers M. J. E., Oury C., Schulte V., Feijge M. A. H., Hoylaerts M. F., Lindhout T., Nieswandt B., Heemskerk J. W. M.
Identification of a novel inhibitory monoclonal antibody against the integrin a2b1
Schoolmeester A., Vauterin S., Vanhoorelbeke K., Deckmyn H.
Identification of a quantal unit mediating platelet tethering and microparticle formation through glycoprotein Ibalpha–VWF interaction
Reininger A. J., Ruggeri Z. M.
Identification of an integrin-associated chloride channel in human platelets
Larkin D., Reilly D., Edwards R. J., Cahill D. J., Moran N.
Inactivation of the human P2Y12 receptor by thiol reagents requires interaction with both extracellular cysteine residues, C17 and C270
Ding Z., Kim S., Dorsam R. T., Jin J., Kunapuli S. P.
Increased shear rate threshold in mouse blood for the dependence of platelet thrombus formation on glycoprotein Iba
Ruggeri Z. M., Marchese P., Kanaji T., Mendolicchio L., Ware J.
Influence of anti-thrombin on platelet adhesion onto immobilized fibrinogen in simulated low flow in vitro system
Loncar R., Stoldt V., Zotz R. B., Niesen T., Hellmig S., Scharf R. E.
Influence of flow on inhibition of platelet dependent thrombin generation by an anti-GPIIb/IIIa antibody
Thomas S., Rigsby P., Goodall A. H., Gray E.
Integrin a2b1 stimulates platelet spreading through protein tyrosine phosphorylation and calcium mobilization
Inoue O., Suzuki-Inoue K., Frampton J., Dean W. L., Watson S. P.
Integrin aIIbb3 outside-in calcium signals sustain platelet–fibrinogen interactions under flow
Hughan S. C., Goncalves I., Schoenwaelder S. M., Yap C. L., Yuan Y., Jackson S. P.
Integrin aVb3 dependent adhesion and spreading under shear stress is particular dependent on the two phenylalanines in the highly conserved GFFKR-region
Ahrens I., Moran N., Meede G., Connolly P., Fitzgerald D.J., Bode C., Peder K.
Integrin activation upon human platelet adhesion to collagen under flow
Lecut C., Schoolmeester A., Deckmyn H., Jandrot-Perrus M., Heemskerk J. W. M.
Integrin clustering mechanisms explored with a soluble aIIbb3 ectodomain construct
Hantgan R. R., Gibbs W., Alspaugh E., Stahle M. C., Mallett T. C., Rocco M., Aster R. H., Peterson J. A.
Interacting sites within Talin and the integrin b3 cytoplasmic tail
Kreis S., Melchior C., Tremuth L., Schaffner-Reckinger E., Kieffer N.
Interaction of CD47 with SHPS-1 negatively regulates platelet function
Kato H., Tomiyama Y., Honda S., Yoshida H., Kashiwagi H., Kosugi S., Shiraga M., Kiyoi T., Honma N., Kurata Y., Matsuzawa Y.
Intermolecular forces of individual aIIbb3-fibrinogen and aVb3–osteopontin interactions on platelets
Litvinov R. I., Bennett J. S., Shuman H., Weisel J. W.
Interplay of glycoprotein Iba, integrin a2b1 and glycoprotein VI is required for human thrombus formation under flow
Siljander P. R.-M., Munnix I. C. A., Smethurst P. A., Deckmyn H., Lindhout T., Ouwehand W. H., Farndale R. W., Heemskerk J. W. M.
Labrirhagin, a protein with metalloprotease and disintegrin domains from Trimeresurus albolabris venom, activates platelets by a mechanism involving GPVI, aIIbbIII3
Doermann D., Navdaev A., Clemetson J. M., Kehrel B. E., Clemetson K. J.
Ligand binding to GP IIb–IIIa and stimulation of platelet release reactions
Mauzurov A. V., Naimushin Y. A.
Mechanisms of conformational activation of prothrombin by staphylocoagulase and fibrinogen substrate recognition
Panizzi P. R., Friedrich R., Verhamme I., Anderson P. J., Huber R., Fuentes-Prior P., Bode W., Bock P. E.
Mechanotransduction through glycoprotein Iba induces a unique series of morphologic changes in translocating platelets
Maxwell M. J., Dopheide S. M., Turner S., Mistry N., Jackson S. P.
Multimerin supports platelet adhesion by functioning as an RGD ligand for platelet integrin receptors
Joshi N. B. J., Zheng S., Kelton D., Horsewood I., Sandhu A. S., Hayward C. P. M.
Murine (m) aIIb out-competes human (h) aIIb for mouse b3 in a transgenic mouse model: Implications for integrin subunit interactions
Thornton M. A., Zhang C., Frampton J., Kowalska M. A., Poncz M.
Normal arterial thrombus formation in integrin a2-deficient mice
Gruener S., Schulte V., Holtkoetter O., Eckes B., Nieswandt B.
Novel polymorphic short tandem repeat in the human a2 integrin gene promoter is associated with GPIa/IIa density on the platelet surface
Sydor W. J., Sanak M., Bazan-Socha S., Szczeklik A., Musial J.
Plasminogen activator inhibitor-1 promotes fibrosarcoma cell migration by modifying cellular attachment to vitronectin via a vb 5 integrin
Urano T., Takahashi T., Suzuki K., Ihara H., Mogami H.
Platelet endothelial cell adhesion molecule-1 (PECAM-1) of platelets is cleaved under high shear stress
Naganuma Y., Satoh K., Yi Q., Asazuma N., Yatomi Y., Ozaki Y.
P-Selectin deficiency results in impaired thrombus formation and frequent embolization in mouse model of carotid artery thrombosis
Jirouskova M., Chereshnev I., Vaanaanen H., Coller B. S., Smyth S. S.
Recombinant proteins mimicking an integrin a2b1 cytoplasmic tail heterodimer
Kreis S., Kieffer N.
Role of the affinity state of the a IIbb 3 receptor for fibrinogen in the formation and reversibility of model particle and platelet aggregation in shear
Frojmovic M., Bonnefoy A., Labarthe B., Legrand C.
Specific interaction of the proteolytic SPII fragment of von Willebrand factor with fibrin
Keuren J., Baruch D., Legendre P., Girma J.-P., Lindhout T.
The peptide LSARLAF directly induces a conformation change in the platelet integrin aIIbb3
Taylor D., Derrick J. M., Cho M. J., Loudon R. G., Gartner T. K.
The role of integrin alpha2beta1 during activation of protein tyrosine kinases induced by low concentration of collagen
Kralisz U., Stasiak M., Cierniewski C. S.
Thrombospondin triggers P-selectin expression and phosphatidyl serine exposure on platelets
Le Courvoisier-Flaujac C., Adam F., Guillin M.C., Jandrot-Perrus M.