Subject Index
Coagulation Factors and Inhibitors
Fibrinolysis, fibrinogen, fibrin
Haemorrhagic Disorders
Invited
Other
Platelets
Thrombotic Disorders and antithrombotic therapy
Vascular Biology
Coagulation Factors and Inhibitors
Animal and experimental models
AT, HCII, serine protease inhibitors
Contact phase
Factor IX and vitamin K-dependent factors
Factor XIII
Factor VIII, factor V
Methods
Other coagulation factors and inhibitions
Procoagulant phospholipids
Protein C, protein S, thrombomodulin
Structural biology and drug design
Thrombin, thrombin receptors
Tissue factor, TFPI, factor VII
In vivo activated protein C (APC) neuroprotective activity involves endothelial protein C receptor (EPCR) and protease activated receptor 1 (PAR-1)
Griffin J. H., Liu D., Cheng T., Fernandez J. A., Castellino F., Rosen E. D., Fukudome K., Zlokovic B. V.
A new screening assay for abnormalities in the Protein C anticoagulant pathway
Safa O., Smirnow M., Thomas E., Lawson D.
Activated protein C (APC) blocks p53-mediated apoptosis in ischemic human brain endothelium through endothelial protein C receptor (EPCR) and protease activated receptor 1 (PAR-1)
Griffin J. J., Cheng T., Liu D., Fernandez J. A., Fukudome K., Zlokovic B. V.
Activated protein C as a proteolytically activable antioxidant, anticoagulant protein
Yamaji K., Abeyama K., Kawahara K., Wang Y., Liu Y., Hashiguchi T., Maruyama I.
Activated protein C generation is greatly decreased in plasma from newborns compared to adults in the presence or absence of endothelium
Berry L. R., Patel S., Chan A. K. C.
Activated protein C induces angiogenesis in vivo and in vitro
Uchiba M., Okajima K., Oike Y., Ito Y., Suda T.
Analytical comparison of recombinant and plasma-derived activated protein C (APC)
Weber A., Nikolic N., Varadi K., Turecek P. L., Schwarz H. P.
Assessment of diagnostic procedures, ratio method and posterior probability method, for protein C deficiency using protein C and antithrombin activities
Sakata T., Mannami T., Okamoto A., Kario K., Katayama Y., Miyata T.
Behaviour of the protein C (PC)/protein S (PS) ratio in patients with thrombosis
Blanco A., Gennari L. C., Nadal M. V., Domínguez M. P., Meschengieser S., Lazzari M. A.
Characterization of a thrombomodulin binding site on protein C and its distinction from an activated protein C binding site for factor Va
Gale A. J., Griffin J. H.
Circulating activated protein C in Behcet's disease and risk of thrombosis
España F., Vayá A., Villa P., Todolí J., Calvo J., Ricart J. M., Medina P., Estellés A., Navarro S., Micó M. L., Aznar J.
Degradation pathway of the naturally occurring mutants of protein C and plasmin inhibitor by the proteasome
Nakahara M., Koyama T., Shibamiya A., Nakazawa F., Hirosawa S.
Detection of Thrombomodulin (TM) Ala455Val polymorphism using sequence-specific primer–polymerase chain reaction (PCR) in patients with severe obstetric complications
Ayman I., Ibrahim A. H., Perez-Casal M., Alfirevic Z., Toh C. H.
Determinations of plasma protein C activity and antigen levels in patients with liver diseases and its clinical significance
He X. F., Wen Z. B., Xiong S. L., Han J. Z., Li J. C., He S. L.
Drotrecogin alfa (activated) inhibits degradation of cytokine-mRNA in an endothelial model of inflammation
Brueckmann M., Lang S., Weiler H. M., Liebe V., Hoffmann U., Borggrefe M., Haase K. K., Huhle G.
Elevated soluble thrombomodulin levels in patients with acute coronary syndrome: down-regulation by anticoagulant dosage of low molecular weight heparins
Hoppensteadt D., Florian-Kujawski M. R., Leya F., Kereiakes D. J., Lewis B., Fareed J.
Eosinophils as a novel target for protein C
Feistritzer C., Sturn D. H., Kaneider N. C., Wiedermann C. J.
Ethnic differences in the frequencies of polymorphisms of protein S and protein C in South African populations
Nel M. J., Gaillard M.-C., Thomson P. D.
Expression of endothelial protein C receptor by human neutrophils and its role in cell migration
Sturn D. H., Kaneider N. C., Feistritzer C., Djanani A., Wiedermann C. J.
Functional impairment of protein S in carriers of the prothrombin G20210A mutation
Koenen R.R., Tans G., van Oerle R., Hamulyák K., Rosing J., Hackeng T.M.
Functional protein S testing does not exclude protein S deficiency
Rodger M. A., Carrier M., Gervais M., Rock G.
Gene array transcript profiling of human endothelial cells identifies pathways regulated by Drotregocin alfa (activated)
Brueckmann M., Lang S., Weiler H. M., Liebe V., Hoffmann U., Borggrefe M., Haase K. K., Huhle G.
Genetic coregulation of C4b-binding protein (C4BP) and free Protein S plasma levels: a link between complement and hemostasis
Esparza-Gordillo J., Soria J.M., Buil A., Martinez-Marchan E., Martinez-Sanchez E., Souto J.C., Almasy L., Blangero J., Rodriguez De Codoba S., Fontcuberta J.
Genetically defined protein S (PS) deficiency is associated with venous thrombosis
Biguzzi E., Fontana G., Castaman G., Razzari C., Margaglione M., Prisco D., Castori L., Brancaccio V., Bucciarelli P., Faioni E. M., on behalf of PROSIT, Protein S Italian Team, Italy
Gla-domain mutated human protein C demonstrating enhanced inactivation of both factor Va and factor VIIIa
Sun Y., Norstrom E., Dahlbäck B.
High-level in vitro expression of protein S after modifications of protein S cDNA
Rezende S. M., Razzari C., Simmonds R. E.
Human endothelial cell protein C receptor (EPCR) expression: role of proximal and distal 5'-gene regulatory elements
Crawley J., Follows G. A., Cockerill P. N., Mollica L., Bonifer C., Simmonds R. E., Wells D. J., Lane D. A., Rance J. B.
Impaired interaction of protein C Gla domain variants with the endothelial cell protein C receptor (EPCR)
Preston R., Villegas-Mendez A., Hermida J., Simioni P., Tormene D., Lane D. A., Simmonds R. E., Philippou H.
Investigation of plasma related influence factors of a new protein S activity assay (protein S Ac®)
Patzke J., Merz M., Siegmund A.
Modulation of thrombin signaling by internalization of thrombin and thrombomodulin complex
Huang H. C., Wu C. M., Shi G. Y., Wu H. L.
New chromogenic screening assay for detecting deficiencies in protein C and protein S
Smirnov M., Safa O., Thomas E., Lawson D.
Plasma levels of soluble thrombomodulin and plasma thrombomodulin cofactor activity in the thrombin mediated activation of protein C: a comparative study
Öhlin A., Larsson K., Hansson M.
Platelet factor 4 up-regulates protein C activation relative to TAFI activation
Mosnier L. O., Bouma B. N., Griffin J. H.
Platelets regulate protein C activity
Räike P.
Prediction and prevention of thrombosis during pregnancy and oestrogen use
Ivey L. M., Staton J. M., Maslen K. E., Sayer M. S., Hughes Q. W., Barden A. E., Singh R., Beilin L. J., Baker R. I.
Prevalence of activated protein C – resistance (APC-R) in patients with thromboembolic events: the first report from Iran
Latifzadeh S., Entezari V., Shashaani T., Jazebi M.
PROS1 mutations that introduce a premature termination codon explain protein S deficiency by nonsense-mediated mRNA decay
Muñoz X., Espinosa-Parrilla Y., Hurtado B., Navarro G., Domènech P., Pérez-Riba M., Sala N.
PROSIT: functional analysis of identified PROS1gene mutations
Razzari C., Simmonds R. E., Biguzzi E., Castaman G., Margaglione M., Faioni (for Prosit) E. M., Lane D. A.
Protein C levels in critically ill ICU patients: differences seen between patients with and without sepsis
Gosselin R. C., Roach D. M., King J. H., Larkin E. C., Alberston T., Owings J. T.
Protein C, S and antithrombin III levels in patients with acute mechanical valve thrombosis
Ayaz S., Yilmaz S., Tutun U., Ulus T.
Protein S confers neuronal protection during ischemic/hypoxic injury in mice
Liu D., Guo H., Griffin J. H., Fernandez J. A., Zlokovic B. V.
Recombinant activated protein C (drotrecogin) is effective for purpura fulminans secondary to severe genetic protein C deficiency
Manco-Johnson M., Knapp-Clevenger R.
Recombinant murine activated protein C is neuroprotective in a murine ischemic stroke model
Fernandez J. A., Xu X., Liu D., Zlokovic B. V., Griffin J. H.
Reduced protein C and S activity and sickle cell disease severity
Schnog J., Meijer J., Duits A., Rojer R., Mac Gillavry M., Ten Cate H., Brandjes D.
Reduced sensitivity to aPC after fish oil supplementation via increased LDL and platelet microparticle formation
Englyst N. A., Byrne C. D.
Role of protein C system in the advancement of activation zone of coagulation: A two-dimensional mathematical model
Barynin Y. A., Vystavkin A., Khanin M. A.
Subcutaneous administration of protein C
Mathias M., Khair K., Burgess C., Liesner R.
The 4678G/C polymorphism in the endothelial protein C receptor (EPCR) gene is associated with levels of soluble plasma EPCR
Medina P., Mira Y., Villa P., Estellés A., Vayá A., Navarro S., Ferrando F., Aznar J., Bertina R. M., Woodhams B., Migaud-Fressart M., España F.
The 4678G/C polymorphism in the endothelial protein C receptor (EPCR) gene reduces the risk of venous thromboembolism in carriers of the factor V Leiden mutation
Navarro S., Medina P., Vayá A., Estellés A., Villa P., Mira Y., Ferrando F., Aznar J., Bertina R. M., España F.
The fourth epidermal growth factor-like domain of thrombomodulin interacts with the basic exosite of protein C
Yang L., Rezaie A. R.
The human protein C gene promoter is regulated by androgenic but not oestrogenic factors
Andia A., Spray J. R. K., Winship P. R.
The natural anticoagulant Thrombomodulin has radical scavenging activity and acts as an antioxidant C-type lectin
Maruyama I., Yamaji K., Kawahara K., Sarker K. P., Iino S., Yamakuchi M., Stern D. M., Abeyama K.
The regulation of thrombin formation by protein S in plasma in the absence of APC
Seré K. M., Rosing J., Hackeng T. M.
The study on phenotype and genotype of Protein C in a Chinese family with hereditary Protein C deficiency
Liu L., Guo W. R., Huang F. Q., Li J. Z., Schlelgel N.
Tissue-specific regulation of protein S gene transcription
De Wolf C. J. F., Bertina R. M., Vos H. L.
Treatment of patients with VWD requiring elective surgery with a pasteurized von Willebrand Factor/FVIII concentrate (Haemate®P) – the use of a PK-guided approach
Lethagen S. R., Kyrle P. A., Schulman S., Haertel S., Muysers C., Mannucci P. M.
Treatment of thrombotic complications and prophylactic use of protein C concentrate in two homozygous protein C deficient patients during surgery
Hertfelder H. J., Kornbrust A. M., Pannier-Fischer M., Rabe E., Hanfland P., Lentze M. J.