The VEINES-QOL/Sym Questionnaire Is a Valid and Reliable Measure of Quality of Life in Patients with Deep Venous Thrombosis
Abstract number: P1634
Kahn1 SR, Lamping2 DL, Ducruet1 T, Arsenault1 L, Miron3 MJ, Roussin3 A, Desmarais4 S, Joyal3 F, Kassis5 J, Solymoss6 S, Desjardins7 L
11Centre for Clinical Epidemiology and Community Studies, Jewish General Hospital, Montreal, Canada 11Centre for Clinical Epidemiology and Community Studies, Jewish General Hospital, Montreal, Canada 22Health Services Research Unit, London School Hygiene & Tropical Medicine, London, UK 33Department of Medicine, Hopital Notre Dame, Montreal, Canada 44Department of Medicine, Hopital Pierre Boucher, Longueuil, Canada 55Department of Medicine, Hopital Maisonneuve Rosemont, Montreal, Canada 66Department of Medicine, McGill University Health Centre, Montreal, Canada 77Department of Medicine, CHUL, Quebec, Canada
Background: To date, there is no fully validated disease-specific quality of life measure for use in venous thrombosis.
Objective: To assess the validity of VEINES-QOL/Sym, a patient-reported questionnaire, for the evaluation of quality of life and symptoms in patients with DVT.
Design of study: Psychometric study within the Venous Thrombosis Outcomes (VETO) Study, a research program on long term outcomes after venous thrombosis.
Setting: Seven hospitals in the province of Quebec, Canada.
Subjects: 359 English and French-speaking patients with acute, objectively diagnosed DVT who participated in the VETO study.
Outcome measure: The 26-item VEINES-QOL/Sym is a patient-reported questionnaire that was originally developed and validated for use in patients with chronic venous disorders of the leg. It generates separate summary scores for symptoms (VEINES-Sym) and quality of life (VEINES-QOL). We evaluated the acceptability, reliability, validity and responsiveness of VEINES-QOL/Sym in patients with acute DVT.
Results: Standard psychometric tests confirmed that VEINES-QOL/Sym fully meets accepted criteria for acceptability (missing data, item endorsement frequencies, floor and ceiling effects), reliability (internal consistency, item-total and inter-item correlations, test-retest), validity (content, construct, convergent, discriminant, known groups) and responsiveness to clinical change in patients with deep vein thrombosis.
Conclusions: The VEINES-QOL/Sym is a practical and scientifically sound patient-reported measure of outcomes that was developed using gold-standard methods. Our results indicate that VEINES-QOL/Sym is valid and reliable for use as a measure of quality of life and symptoms in patients with acute DVT. VEINES-QOL/Sym provides a rigorous tool to allow more comprehensive evaluation of outcomes in clinical trials and epidemiological studies of patients with DVT.
To cite this abstract use the following format:
Journal of Thrombosis and Haemostasis 2005; Volume 3, Supplement 1: abstract number
|Session name:||XXIst ISTH Congress|
|Subject:||Poster Session Wednesday|
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