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L
Labarthe B. - Role of the affinity state of the a IIbb 3 receptor for fibrinogen in the formation and reversibility of model particle and platelet aggregation in shear
Lablanche J. M. - Tissue factor predicts long-term outcome after percutaneous coronary revascularization
Labrouche S. - In vitro and ex vivo study of the effects of core pentasaccharide and of longer heparin chains on latent antithrombin (AT)
  - The thrombin generation test (TGT) may be a predictive parameter for thrombus formation during endovascular embolization of cerebral aneurysms
Labrouche S. - LPS-activation of THP-1 cells: effect of anti-thrombin studied by in vivo footprinting of the tissue factor (TF) gene promoter
Lacerda P. - Association of MTHFR and ACE gene polymorphisms in reflux associated with renal damage
  - A different view on the inflammatory bowel disease – the role of adhesion molecules and angiogenic growth factors
Lachana A. - Factor VIII inhibitor in a patient with multiple sclerosis and interferon regimen
Lacroix-Desmazes S. - Perturbations in the blood T-cell repertoire of inhibitor-positive patients with severe hemophilia A
  - Peptide decoys selected by phage display block in vitro and in vivo activity of a human anti-FVIII inhibitor
Lacroix-Desmazes S. - Kinetics of hydrolysis by anti-FVIII antibodies in hemophilia A
Laduca F. - Precision of INR (International Normalized Ratio) measurement using laboratory and point-of-care assays: Understanding the impact of system influence on patient management
Laduca F. M. - Safety of low intensity warfarin regimen in Chinese patients With mechanical heart valve prostheses
Laduca F. - A novel recombinant tissue factor assay for measuring the anti-Xa effect of Low-Molecular-Weight Heparin (LMWH): implications for interventional coronary procedures
Laffan M. A. - Two novel mutations in severe factor VII deficiency
Laffan M. - Clinical manifestation of severe hemophilia B ameliorated by Prothrombin 20210A
Lages G. F. G. - Hemostatic parameters in Brazilian asymptomatic carriers of Factor V Leiden, prothrombin (G20210A) and methylenetetrahydrofolate reductase (C677T) mutations
  - Markers of hypercoagulability in Brazilian patients with DVT undergoing oral anti-coagulation therapy
Laggner A. N. - High prevalence of aspirin resistance in patients with acute coronary syndromes
Lago A. - Insufficient thromboxane A2 inhibition in patients with vascular disease chronically treated with aspirin: implications for platelet function
Laguna P. - Immune tolerance induction in the treatment of children with haemophilia A complicated by factor VIII inhibitor
  - Hemorrhage into the right cerebella hemisphere in hemophiliac boy with factor VIII inhibitor
Lahary A. - Hypercoagulability in sickle cell disease: increased monocyte tissue factor expression and increased erythrocyte microparticles expressing phosphatidyl serine
Laibbe S. - Interest of VASP measurement on patients treated by thienopyridines
  - Evaluation of aspirin resistance by platelet function analyzer (PFA-100™) in patients with acute coronary syndrome®
Laing G. - Characterization of novel platelet and procoagulant activities from Bothrops cotiara snake venom
Lak M. - Prenatal diagnosis of dysprothrombinemia in an Iranian family
  - Reporting presence of 9 novel mutations in hemophilia B patients in Iran
Lak M. - Analysis of 100 Iranian patients with factor XIII (sub unit A) deficiency
Lak M. - Rapid screening of factor IX mutations by SSCP and sequencing in 50 Iranian families
Lake J. R. - Successful liver transplantation in a hemophilia A patient with high titer factor VIII inhibitor
Lalezari S. - Clot from platelet rich plasma promotes wound healing
Lally C. - Association of plasma homocysteine, serum folate, and red-blood cell folate with venous thromboembolism in American whites and blacks: the GATE study
  - Relationship of the Val34Leu polymorphism in the factor XIII gene with venous thromboembolism in American whites and blacks: the GATE study
Lalor P. - Platelet deposition in the microvasculature of transplanted human liver provides an adhesive substrate for the recruitment of recipient leukocytes
Lalouschek W. - Impact of platelet glycoprotein Ibalpha Kozak polymorphism on risk of ischemic cerebrovascular events
Lam S. C. T. - Effect of cellular and receptor activation on the extent of integrin alphaIIb beta3 internalization
Lamanuzzi L. - Inhibition of human neutrophils plasminogen activation by elastase-derived apolipoprotein(a) fragments
Lambert T. - Response to DDAVP in mild/moderate hemophilia A patients according to the underlying factor VIII genotype
Lambert M. - Interest of diluted Russel viper venom time (dRVVT) in determining “pathogenic” lupus anticoagulants
Lambert T. - Effect of type of treatment (recombinant vs. plasmatic) on FVIII inhibitor incidence according to known risk cofactors in previously untreated severe hemophilia A patients (Pups)
Lambert J. - Splice site mutations of the von Willebrand factor gene in patients previously diagnosed with von Willebrand disease type 1
Lambert T. - Enhanced procoagulant and antifibrinolytic potential of superactive variants of recombinant factor VIIa in plasma from patients with severe haemophilia A
Lambiasi M. G. - cAMP inhibits convulxin-induced calcium mobilization; differences with collagen
Lambie J. - Venous thrombo-embolism in the black population
Lambrogiannakis E. - Is there an hypercoagulable state after treadmill exercise in patients with atrial fibrillation?
  - Obesity and coagulation. Is there any correlation?
  - Correlation SVCAM, SICAM plasma levels with the outcome of treadmill test and with attitudinal factors for coronary artery disease in patients without previous history of ischemic heart disease
Lambropoulos A. F. - High frequency of factor V Leiden and prothrombin G20210A mutations in Greek hemophiliacs
Lammi A. T. - Warfarin-induced skin necrosis in a child with protein C deficiency and Factor V Leiden mutation
Lämmle B. - Splenectomy in relapsing and plasma-refractory thrombotic thrombocytopenic purpura
Lammle B. - Long-term outcomes following recovery from thrombotic thrombocytopenic purpura – hemolytic uremic syndrome (TTP-HUS) measured by health-related quality-of-life (QOL) assessments
Lämmle B. - Multicenter comparison of assays for von Willebrand factor-cleaving protease (ADAMTS13) activity
Lämmle B. - Pathogenesis, diagnosis and therapy of TTP
Lämmle B. - Towards the development of a recombinant von Willebrand factor-cleaving protease (ADAMTS-13)
  - Titer of anti-heparin/PF4-antibodies and extent of in vivo activation of the coagulation and fibrinolytic systems
  - Observations on immunoadsorption (IA) as an auxiliary therapy for acquired thrombotic thrombocytopenic purpura (TTP)
  - ADAMTS13 gene defects in two brothers with constitutional thrombotic thrombocytopenic purpura and normalization of von Willebrand factor-cleaving protease activity by recombinant human ADAMTS-13
Lammle B. - Analysis of ADAMTS13 activity in consecutive patients with clinically diagnosed thrombotic thrombocytopenic purpura – hemolytic uremic syndrome (TTP-HUS)
LaMonte M. - The safety profile of Argatroban in acute stroke: results of a prospective trial
Lamotte M. - The Asp299Gly polymorphism of Toll-like receptor 4 as a genetic risk factor for acute coronary events
Lamping D. L. - Patients with the post–thrombotic syndrome have worse disease severity and quality of life than patients with primary chronic venous disease
Lamping D. - Resource utilization and loss of productivity during the 4 months following a diagnosis of deep venous thrombosis
Landmann H. - Hiruquant®, a new simple and quick assay for monitoring of hirudin therapy
Landray M. - Markers of inflammation, coagulation, endothelial damage and platelet activation in chronic renal disease
Landry F. - Baseline thrombophilic markers do not predict deep venous thrombosis in medical–surgical ICU patients
Lane D. A. - PROSIT: functional analysis of identified PROS1gene mutations
  - Roles of low specificity and cofactor interaction sites on thrombin during factor XIII activation: competition for cofactor sites on thrombin determines its fate
  - Human endothelial cell protein C receptor (EPCR) expression: role of proximal and distal 5'-gene regulatory elements
  - Impaired interaction of protein C Gla domain variants with the endothelial cell protein C receptor (EPCR)
  - Factor V Gly2112Asp, a C2-domain variant, is associated with severe deficiency and a bleeding tendency
Lang W. - Abciximab reduces monocyte tissue factor after carotid angioplasty and stenting: role of monocyte platelet cross talk in cerebral microembolization
  - Abciximab reduces monocyte tissue factor after carotid angioplasty and stenting: role of monocyte platelet cross talk in cerebral microembolization
Lang S. - Gene array transcript profiling of human endothelial cells identifies pathways regulated by Drotregocin alfa (activated)
Lang B. J. - APTT transmittance waveform analysis in a cohort of septic patients
Lang S. - Drotrecogin alfa (activated) inhibits degradation of cytokine-mRNA in an endothelial model of inflammation
Lang W. - Impact of platelet glycoprotein Ibalpha Kozak polymorphism on risk of ischemic cerebrovascular events
Langdown J. - The use of corn trypsin inhibitor to reduce the effect of sample contact activation in assays utilizing low tissue factor
Lange U. - Determination of direct thrombin inhibitors like hirudin in plasma – Comparison of the Ecarin Chromogenic Assay (ECA) with the Ecarin Clotting Time (ECT) and the Activated Partial Thromboplastin Time (APTT)
Lange U. - Anti-endothelial cell antibodies (AECA): cDNA-based antigen screening
Langhoff F. - PTS after calf vein thrombosis (CVT): a 10-year follow-up
Langhorne P. - Thrombophilia in pregnancy, combined oral contraceptives and hormone replacement therapy users: a systematic review
  - Screening for thrombophilia: an economic assessment
  - The risk of thromboembolism and the effectiveness of prophylactic treatment in thrombophilia patients undergoing major orthopaedic surgery: a systematic review
Langsenlehner U. - Association of a common 936 C/T polymorphism in the gene of vascular endothelial growth factor and VEGF plasma levels
Lanir N. - Mechanisms for acquired activated Protein C resistance in cancer patients
  - The hemostatic balance between tissue factor (TF) and tissue factor pathway inhibitor (TFPI) in cultures of human primary trophoblasts
Lanir N. - Endothelial protein C receptor (EPCR) is expressed in placental villi and cultured syncytiotrophoblasts
Lanir N. - Modulation of systemic and placental hemostatic mechanisms by enoxaparin in women with gestational vascular complications
Lanke E. - The molecular background to von Willebrand disease type 1 in Sweden
Lankes W. - Combination therapy with low-molecular-weight heparin and glycoprotein IIb/IIIa inhibitors in acute coronary syndromes: insights from the Global Registry of Acute Coronary Events (GRACE)
  - Combination therapy with low-molecular weight heparin and glycoprotein IIb/IIIa inhibitors in acute coronary syndromes: insights from the Global Registry of Acute Coronary Events (GRACE)
Lanning L. - DRVVT testing for lupus identification: a comparison of two methods
Lanoye P. - A prospective randomized study to assess the usefulness of venous compression ultrasonography (CUS) and plasma d-dimer (DD) assay in the decision to discontinue treatment with a vitamin K antagonist (VKA) after an acute deep-vein thrombosis (DVT)
Lanza F. - PLC g-dependent GPIb signaling following platelet adhesion to von Willebrand factor through a pathway distinct from FcR g chain and FcgRIIA
  - Evidence for a PLCg2-independent alpha2beta1-triggered signalling pathway contributing to platelet aggregation in response to collagen
  - Cytoskeletal regulation of the adhesive interactions between the platelet GPIb/V/IX receptor and von Willebrand factor
Lapecorella M. - Short-term effects of raloxifene on the main anti-coagulant systems in postmenopausal women
Lapini I. - Optimization of human 14 000 oligonucleotide-microarrays and study design for the evaluation of gene expression profiling in cardiovascular diseases
Laporte S. - Clinical experience with optional cava filters
  - A meta-analysis on the benefit-to-risk ratio of Vitamin K antagonists (VKA) in the prevention of venous thromboembolism in major orthopedic surgery
Laporte S. - Predictive factors of cancer discovery after deep-vein thrombosis: a 8-years follow-up study
Laporte S. - Factors predicting venous thrombotic complications after superficial–vein thrombosis
  - Differences between predictive factors for PE and DVT recurrences: results from 5 randomized trials
Laposata M.† - The effect of drotrecogin alfa (Xigris) on the biphasic PTT waveform in patients with sepsis
Lari B. - Evaluation of the fibrinolytic capacity before and after venous occlusion performed by serum d-dimer test after standardized coagulation
  - TAFI plasma levels are not increased in ischemic heart disease patients admitted to a coronary care unit
  - Increased lipoprotein(a) levels as an independent risk factor for idiopathic and recurrent venous thrombosis
Larina L. E. - Using NovoSeven (NS) – recombinant factor VIIa to control the bleedings in Bernard-Soulier (BSS) girl. Case report
  - The experience of treatment of children with hemostasis system pathology treatment with recombinant factor VII NovoSeven
Larini P. - Inferior vena cava filters: personal experience on 322 devices, with regard also to medical treatment during long-term follow-up
Larionova N. - Development of novel delivery systems of aprotinin
Larkin D. - Identification of an integrin-associated chloride channel in human platelets
Larkin E. C. - Protein C levels in critically ill ICU patients: differences seen between patients with and without sepsis
Larnkjaer A. - Comparison of TFPI release of various LMW heparins based on the molecular weight distribution of the LMW heparins and a model describing the TFPI release according to molecular mass
LaRocca T. - P2Y12 regulates platelet adhesion/activation, thrombus growth and thrombus stability in injured arteries
Larocca T. - Anticoagulants (thrombin inhibitors) and aspirin synergize with P2Y12 receptor antagonism in thrombosis
Larsen H. - Development of inhibitors against factor VII in patient with severe factor VII deficiency
Larsen L. F. - In vitro effect of recombinant activated factor VII on thrombin generation and clot formation in blood from patients on vitamin K-antagonist therapy
Larsen F. - Spiral computed tomography has a higher sensitivity and specificity than d-dimer in the diagnosis of acute pulmonary embolism
  - A comparison of spiral computed tomography and latex agglutination D-dimer assay in acute pulmonary embolism using pulmonary arteriography as Gold Standard
Larson P. - Evaluation of IgG formation to trace mammalian proteins in hemophilia patients treated with a recombinant therapeutic protein preparation
  - Stability of rFVIII-FS after continuous infusion using a mini-pump infusion device
Larson P. J. - Probabilistic modeling of population-based epidemiology and treatment modalities to determine unconstrained factor VIII demand
Larson P. - Pharmacokinetics of functional von Willebrand Factor (VWF) with infusion of Koate-DVI® in patients with von Willebrand's Disease (VWD)
  - Health-related quality of life in adults with hemophilia: the patient perspective
Larsson R. - Surface deposited fibrin activates factor XII and the intrinsic coagulation pathway
  - The activation of inflammation and coagulation by different heparin surfaces
Larsson K. - Plasma levels of soluble thrombomodulin and plasma thrombomodulin cofactor activity in the thrombin mediated activation of protein C: a comparative study
Lasierra J. - Biological effects of sulodexide on hemostatic risk factors of thrombogenesis
  - Is sulodexide an alternative treatment in the prophylaxis of thromboembolic disease?
  - Deep venous thrombosis of the arm: comparison of sulodexide and acenocoumarol for the secondary prevention of venous thromboembolism
Lasne D. - Extracorporeal adsorption of Factor VIII antibodies on randomly functionalized polystyrene resins
Lassen M. R. - A comparison of survival rates at 8–10 years for hip-fracture patients given thromboprophylaxis with enoxaparin vs. unfractionated heparin
  - No episode of thrombocytopenia after four-week administration of fondaparinux, a new synthetic and selective inhibitor of factor Xa, in the PENTHIFRA-PLUS study
  - Consistency of efficacy of extended thromboprophylaxis with fondaparinux (Arixtra) in prevention of venous thromboembolism (VTE) after hip fracture surgery according to different composite efficacy endpoints: the PENTHIFRA-PLUS study
  - Influence of the duration of fondaparinux prophylaxis in preventing venous thromboembolism (VTE) following major orthopedic surgery
  - Prevention of venous thromboembolism in orthopedic trauma patients receiving heparin thromboprophylaxis – a substudy analysis of autopsy-confirmed fatal pulmonary embolism
Lassen M. - Randomized trial of tinzaparin, a low molecular weight heparin (LMWH) vs. placebo in the treatment of mild-to-moderately active ulcerative colitis
Lassen M. R. - Efficacy and safety of the treatment regimen of melagatran and ximelagatran for prevention of thromboembolic events after total hip or knee replacement: a meta-analysis of 3 randomized, double-blind studies, to evaluate the influence of time and dose
  - Relevance of venographic distal thrombus assessment in venous thromboembolism (VTE) prophylaxis studies: lessons from the fondaparinux (Arixtra®) database in major orthopedic surgery
Lassen M. - Absence of transaminase increase after 4-week administration of fondaparinux (Arixtra®), a new synthetic and selective inhibitor of factor Xa, in the PENTHIFRA-PLUS study
Lassen J. F. - The platelet polymorphism PlA2 is a genetic risk factor for myocardial infarction
Lassen M. R. - A new, noninvasive test for rapid detection of coagulation activation
Lassen M. - Evaluating bleeding complications of thromboprophylaxis after hip replacement: a systematic review
Lassen M. R. - Fondaparinux vs. placebo for the prevention of venous thromboembolism in acutely ill medical patients (artemis)
  - Reviparin normalizes tissue factor pathway activation in patients with lower limb immobilization and is not associated with heparin antibody production
  - Persistence of the risk of venous thromboembolism (VTE) for at least four weeks after hip fracture surgery: evidence from the fondaparinux hip fracture surgery database
Lassen M. R. - Efficacy of fondaparinux (Arixtra) in extended thromboprophylaxis in hip fracture surgery is irrespective of patient and surgical characteristics: subgroup analyses of the Penthifra-Plus study
Lassen M. R. - Lower limb trauma is associated with a moderate risk of thrombosis caused by sustained release of tissue factor despite early functional mobilization
Lasser G. W. - CTRP1 – a vascular wall protein that can prevent platelet thrombosis without causing bleeding
Lassila R. - Inhibition of P2Y12-receptor in vivo and in vitro in patients undergoing elective percutaneous coronary intervention (PCI)
  - Tyrosine kinases regulate the activation of phosphatidylinositol 3-kinase in platelets stimulated by the PAR1-activating peptide
  - PECAM-1 expression in adherent platelets differs from that of thrombi during human microvascular anastomosis
Lastoria S. - Efficacy and safety of once-daily Enoxaparin given in the outpatient setting compared with in-hospital unfractionated heparin for treatment of proximal lower limb deep-vein thrombosis
  - Prophylaxis of deep vein thrombosis after lower extremity amputation: comparison of low molecular weight heparin with unfractionated heparin
Laszlo P. - Anti-phospholipid syndrome during pregnancy: only the high-dose of LMWH thromboprophylaxis is successful
Laszló P. - Different blood flow parameters between high-shear conditions in patients with type 1 and type 2 diabetes mellitus
Lathrop M. - A quantitative trait locus on chromosome 11 is the major genetic determinant of homocysteine plasma levels. Results from the GAIT Project
  - Genetic dissection of thrombin-activatable fibrinolysis inhibitor (TAFI)
Latifzadeh S. - Prevalence of activated protein C – resistance (APC-R) in patients with thromboembolic events: the first report from Iran
Lau C. - The prognostic value of platelet count drop in an intensive care unit
Lau A. - Ex vivo thrombin generation capacity in pediatric patients receiving Tinzaparin
Lau C. - Development of the Canadian hemophilia outcomes – Kids Life Assessment Tool (CHO-KLAT)
  - Coagulation inhibitor monitoring rationale in critical patients with severe sepsis
Laubriat M. - Efficacy and safety of the first nanofiltered plasma-derived FVIII (FACTANE®) in previously treated haemophilia A patients
Laude I. - The role of the ATP-Binding Cassette transporter A1 (ABCA1) in phosphatidylserine cell surface exposure and in the modulation of the procoagulant phenotype
Laurendeau I. - A new co-operative effect of low molecular weight polysaccharides and cell surface heparin sulfate in enhancing bFGF-induced endothelial cell differentiation
  - Tissue Factor-603 A–G promoter polymorphism is associated with human monocyte constitutive but not with LPS induced gene expression
Laurenzi I. J. - Kinetic analysis of mutations associated with a platelet adhesion receptor or its ligand reveals similarities between the genetically distinct bleeding disorders known as PT- and type 2B vWD
Laurian Y. - Thrombinography can differentiate bleeding from nonbleeding patients with prolonged APTT
Lauro R. - Increased platelet superoxide anion production in patients with hypertension: role of AT1 receptors
Lauroua P. - Treatment of patients with inhibitors with FEIBA: the French experience from 1995 to 1999
Lausen I. - Prolonged thromboprophylaxis with low molecular weight heparin (tinzaparin) following major general surgery primarily for cancer: An individual patient data meta-analysis
Lavender F. L. - Factor VII Padua: diagnosis based on differential laboratory tests
  - Platelet glycoprotein Iba VNTR polymorphisms: association with thromboembolic diseases
  - Does thromboelastography demonstrate hypercoagulability in patients with both a clinical history of thrombosis and the lupus anti-coagulant antibody?
LAVEND'Homme R. - The C1 domain substitution His2155Asp severely reduces factor VIII binding to von Willebrand factor
  - Deletion of residue Ala2201 in the factor VIII C2 domain impairs FVIII interactions with phospholipids and vWF and results in mild hemophilia A
  - Response to DDAVP in mild/moderate hemophilia A patients according to the underlying factor VIII genotype
Laverda A. M. - Incidence of recurrent ischemic stroke in children with coagulation abnormalities
Lavergne J. M. - Deletion of residue Ala2201 in the factor VIII C2 domain impairs FVIII interactions with phospholipids and vWF and results in mild hemophilia A
Lavergne J.-M. L. S. - Screening for annexin A5 gene mutations and the risk of the C-1T mutation in venous thrombosis and myocardial infarction
Lavergne J. M. - Response to DDAVP in mild/moderate hemophilia A patients according to the underlying factor VIII genotype
  - Identification of intron 1 and 22 inversion mutation in the factor VIII gene of 94 Iranian families with hemophilia A
  - Identification of seven new candidate mutations of ADAMTS13 gene in four French families related to congenital thrombotic thrombocytopenic purpura
Lavielle G. - Influence of selective nonpeptide PAR-1 and PAR-4 antagonists on thrombin-induced aggregation of human platelets
Lavigne G. - Anti-protein Z antibodies in women with abnormal pregnancies
Lavoretano S. - In vitro expression study of four single nucleotide polymorphisms in the ADAMTS13 gene
Lavrentieva N. N. - The principles of therapy of hemorrhagic vasculitis at children
Lavrentyeva N. N. - Plasma glycocalicin level in diagnosis of the idiopathic thrombocytopenic purpura (ITP) in children
Lawler J. - The control of von Willebrand Factor multimer size by thrombospondin-1
Lawler K. - Shear-induced activation of metastatic cells is enhanced by the platelet secreteome and inhibited by aspirin
Lawrence D. - Neuroprotective functions of neuroserpin and PAI-1
Lawrie A. - Using ETP to predict which factor V Leiden heterozygotes will suffer from venous thrombo-embolism
Lawrie A. S. - A novel r-polypeptide, kunitz-type inhibitor with high specificity for plasma kallikrein and potential for therapeutic use
Lawrie A. L. - The effect of pathogen inactivation treatment processes on VWF cleaving protease, VWF:Ag and protein S levels in blood components used in therapeutic plasma exchange for thrombotic thrombocytopenic purpura
Lawrie A. S. - A multicentre assessment of the endogenous thrombin potential using a continuous monitoring amidolytic technique
Lawshe A. - Kinetic analysis of mutations associated with a platelet adhesion receptor or its ligand reveals similarities between the genetically distinct bleeding disorders known as PT- and type 2B vWD
Lawson D. - New chromogenic screening assay for detecting deficiencies in protein C and protein S
Lawson J. - Haemostasis in surgery: Mechanism of action of rFVlla and the potential of control of massive haemorrhage in patients without a pre-existing coagulopathy
Lawson D. - A new screening assay for abnormalities in the Protein C anticoagulant pathway
Lay M. J. - Intrauterine growth retardation and recurrent pregnancy loss associated with prothrombin gene variants 20221C > T and 20209C > T
Layton M. - Two novel mutations in severe factor VII deficiency
Lazaraki G. - Congenital defect of inferior vena cava and thrombophilia Leiden
Lázaro I. - Effect of antiphospholipid antibodies in the activation of the contact complex: importance in the obstetric complications of the antipospholipid syndrome
Lazzari M. A. - Low molecular weight heparin (LMWH) in pregnant women with mechanical prosthetic heart valves (MPHV)
  - Behaviour of the protein C (PC)/protein S (PS) ratio in patients with thrombosis
  - Influence of factor VIII (fVIII) levels in patients treated with DDAVP on the activated protein C resistance (APCR)
  - Cysteine–homocysteine ratio in patients with C677T mutation of the MTHFR gene
  - Comparative study of conformation sensitive gel electrophoresis and DNA sequencing for polymorphisms and mutation detection in von Willebrand disease type 2 N
  - Platelet von Willebrand factor antigen (VWF:Ag-i) in patients with mucocutaneous bleeding tendency and normal von Willebrand factor (VWF) plasma levels
  - Fibrinolytic activity and response to venous occlusion in activated protein C resistance phenotype
  - Prostacyclin protects basal and nitric oxide-induced megakaryocytes apoptosis
  - Prevalence of haemostatic and fibrinolytic abnormalities in women with unexplained embryofetal losses and vascular obstetric complications
  - Characterization of the von Willebrand factor present in circulating PMN
  - Von Willebrand factor cleaving protease (VWFCP) activity in patients with pre-eclampsia history: preliminary results
  - Incidence of major hemorrhages related to surgery in type 1 von Willebrand's disease patients
  - Anti-phospholipid antibodies and hyperhomocysteinemia: response to therapy with folic acid
  - Effects of factor VIII (fVIII) levels and activated partial thromboplastin time (aPTT) in activated protein C resistance (APC-R) ratio using two different methods
  - Anticoagulation therapy outcome in children after extracardiac conduit Fontan operation
  - Control of von Willebrand factor multimer size by a fibronectin related substance
  - Virtual decrease of von Willebrand Factor-cleaving protease (ADAMTS13) after infusion of desmopressin (DDAVP)
  - Flow cytometry analysis of platelet activation throughout normal gestation and puerperium
Lazzerini G. - At least two distinct pathways generating reactive oxygen species mediate endothelial VCAM-1 induction by advanced glycation endproducts
Le Cam-Duchez V. - Thrombophilic risk factors and idiopathic sudden sensorineural hearing loss
Le Cam-Duchez V. - Frequency and effects of cytochrome P450 2C9 polymorphisms in 61 patients treated by warfarin
  - Prethrombotic biological markers in congenital thrombophilic patients. Preliminary results of a randomized long-term secondary prophylaxis study using warfarin and comparing two INR target ranges
Le Cam-Duchez V. - Protein C promoter polymorphisms are potential additional risk factors for cerebral venous thrombosis
Le Courvoisier-Flaujac C. - Thrombospondin triggers P-selectin expression and phosphatidyl serine exposure on platelets
Le Deist F. - A new evidence of a relationship between store-operated calcium entry and the regulation of procoagulant phosphatidylserine exposure at the surface of stimulated cells
Le Moal V. - Prevalence of methylenetetrahydrofolatereductase (MTHFR) gene polymorphism (C677T) in the Moroccan population
Le Moigne-Amrani A. - Prolonged prophylaxis against VTE with enoxaparin in patients undergoing surgery for malignancy: 1-year survival study
Le Quan Sang K. H. - Intravenous immunoglobulins G modulate calcium signals, von Willebrand factor secretion and nitric oxide metabolism in human endothelial cells
Le Querrec A. - Acquired von Willebrand Syndrome: four cases associated with monoclonal gammopathy
  - Comparison of FVIII levels as venous thrombosis risk factor measured by a chromogenic and a coagulant assay
Leadley R. J. - Inhibition of human prothrombinase by PD0313052 reveals advantages of active site-directed factor Xa inhibition
Leadley R. - The Gas6 receptors Axl, Sky, and Mer function to enhance human platelet degranulation and aggregation
  - Compound 48/80 inhibits thrombosis in balloon-injured arteries of hypercholesterolemic rabbits by inhibiting TF/FVIIa-mediated coagulation
Leander K. - Prospective evaluation of t-PA/PAI-1 complex predicting myocardial infarction in controls included in the SHEEP study
  - The t-PA/PAI-1 complex in plasma in relation to risk of myocardial infarction as evaluated in the Stockholm heart epidemiological program (SHEEP)
Leão P. P. - Prevalence of factor V Leiden, FII G20210A, FXIII Val34Leu and MTHFR C677T polymorphisms in cancer patients with and without venous thrombosis
Lear J. D. - Activation of the platelet integrin aIIbb3 by thermodynamic modulation of transmembrane helix associations
Lebos C. - Primordial role of the P2Y12 ADP receptor in different phases of platelet–collagen interactions
Lebret D. - The Asp299Gly polymorphism of Toll-like receptor 4 as a genetic risk factor for acute coronary events
Lecchi A. - Does plasma homocysteine influence the in vitro anti-coagulant response to activated Protein C?
  - Concomitant activation of both the P2Y1-driven Gq and the P2Y12-driven Gi pathways is necessary for normal ADP-induced mobilization of platelet cytoplasmic Ca2+
Lechler R. I. - Expression of human tissue factor pathway inhibitor and hirudin fusion proteins on mouse vascular smooth muscle cells inhibits vascular remodeling after wire-induced carotid artery injury
  - Targeted expression of tissue factor pathway inhibitor and hirudin fusion proteins to endothelial cells reduces pathology in murine LPS-induced endotoxic shock – a novel model to study vascular inflammation
Lechner K. - Is inflammation involved in the development of thrombosis in patients with the lupus anticoagulant?
  - IgG-antibodies (IgG-Ab) against beta-2-glycoprotein I (b2-GPI) are associated with an increased risk for thrombotic events (TE) in patients (pts) with the lupus anticoagulant (LA)
Leclerc P. - The role of the ATP-Binding Cassette transporter A1 (ABCA1) in phosphatidylserine cell surface exposure and in the modulation of the procoagulant phenotype
Leclercq M. - Observer variability in the assessment of clinical probability in patients with suspected pulmonary embolism
Leclercq A. - Metalloproteinase 9 and plasmin as secreted markers of complicated atherosclerotic plaques
Lecompte T. - The thrombin potential in contrast to clotting times is only slightly modified after uncomplicated heart valve replacement in adults
Lecompte T. - Thrombinography can differentiate bleeding from nonbleeding patients with prolonged APTT
Lecompte T. - Increased thrombin potential due to acquired activated protein C resistance in patients with lupus anticoagulants
  - Phenotypic sensitivity to activated protein C in healthy families: importance of genetic components and environmental factors in the Stanislas Cohort
Lecut C. - A new platelet activation marker specific for activated integrin alpha2beta1: monoclonal antibody IAC-1
Lecut C. - Integrin activation upon human platelet adhesion to collagen under flow
Ledford M. R. - Variability of clinical laboratory practice in testing for disorders of platelet function: results of a NASCOLA survey
Lee K. H. - A collaborative study to establish a Korean standard for factor VIII : C concentrate
Lee S. H. - A collaborative study to establish a Korean standard for factor VIII : C concentrate
  - A collaborative study to establish a Korea National Biological Standard for antithrombin III concentrate
Lee K. H. - A collaborative study to establish a Korea National Biological Standard for antithrombin III concentrate
Lee S. H. - A collaborative study to establish a Korea National Biological Standard for antithrombin III concentrate
Lee Y. M. - Oral contraceptives decrease the sensitivity of plasma for the anticoagulant activity of activated protein C (APC) by decreasing plasma glucosylceramide (GlcCer) level
Lee Y. K. - Thrombin-activatable fibrinolysis inhibitor is not associated with the occurrence of ischemic stroke
Lee B. - Thrombin-activatable fibrinolysis inhibitor is not associated with the occurrence of ischemic stroke
Lee K. W. - Abnormal thrombogenesis and endothelial damage/dysfunction is related to ‘nondipping’ pattern of nocturnal blood pressure in patients with coronary artery disease
Lee L. H. - Patterns of cases and impact of venous thromboembolism (VTE) in a tertiary institution in Singapore: defying notions of VTE as a disorder of lower significance among Asians
Lee M. J. - Normal pregnancy is associated with decreased protein Z levels in the second and third trimesters compared to early pregnancy
Lee S. H. - Pharmacokinetics and pharmacodynamics of LB30870, a novel oral low molecular weight direct thrombin inhibitor in healthy volunteers
Lee J. H. - Pharmacokinetics and pharmacodynamics of LB30870, a novel oral low molecular weight direct thrombin inhibitor in healthy volunteers
Lee S. M. - Hereditary coagulation factor deficiencies in Korea
Lee K. S. - Hereditary coagulation factor deficiencies in Korea
Lee J. H. - Polymorphisms of 5,10-methylenetetrahydrofolate reductase gene and risk of Korean acute leukemia
Lee J. A. - Polymorphisms of 5,10-methylenetetrahydrofolate reductase gene and risk of Korean acute leukemia
Lee T. - A novel recombinant tissue factor assay for measuring the anti-Xa effect of Low-Molecular-Weight Heparin (LMWH): implications for interventional coronary procedures
Lee K. - A novel plasma proteinase that enhances incorporation of a2-antiplasmin into fibrin
Lee W. C. - Does DVT exist in Asia? – The AIDA study (assessment of the incidence of Deep Vein Thrombosis in Asia following major orthopedic surgery): study rationale and interim results
Lee K. K. C. - Does DVT exist in Asia? – The AIDA study (assessment of the incidence of Deep Vein Thrombosis in Asia following major orthopedic surgery): study rationale and interim results
Lee C. A. - Promotion of thrombin generation at low FVIII concentrations by FIXa
Lee T. U. - To evaluate the mechanism of neutrophil activation caused by a Cox-2 inhibitor-celecoxib
Lee S. M. - Detection of Ala601-Thr mutation in dysplasminogenemic patients with thrombosis in Korean population
Lee K. W. - Abnormal thrombogenesis and endothelial damage/dysfunction is related to high pulse pressure in patients with coronary artery disease
Lee C. A. - Increased VWF antigen clearance in partial quantitative von Willebrand factor deficiency and reporting of a familial tendency
Lee R. - Correlation of supra-therapeutic (ST) International Normalized Ratio (INR) with vitamin-K-dependent factors (VKDF)
Lee A. Y. Y. - Long-term treatment with dalteparin low-molecular-weight heparin (LMWH) is more effective than oral anticoagulant (OA) therapy in cancer patients with venous thromboembolism (VTE)
Lee Y. M. - Synergy between deficiencies of plasma glucosylceramide and deficiency of activated protein C for venous thromboembolism
Lee A. Y. - From Trousseau to targeted therapy: new insights and innovations in thrombosis and cancer
Lee M. J. - Patients with adverse pregnancy outcome have lower levels of protein Z and protein S compared to patients with normal pregnancy outcome
Lee A. - Ability of d-dimer to reduce the need for diagnostic imaging in patients with suspected pulmonary embolism: A randomized trial
Lee C. J. - A snake venom metalloproteinase reduces neutrophil-platelet adhesion through down-regulation of PSGL-1 expression
Leebeek F. W. G. - Association between genetic variability of von Willebrand factor and peripheral atherosclerosis: the Rotterdam Study
  - Genetic variability of von Willebrand factor and coronary heart disease: the Rotterdam Study
Leebeek F. W. G. - High-dose interferon-alpha induction treatment combined with ribavirin for chronic hepatitis C in congenital coagulation disorders. A randomized, double-blind, placebo-controlled clinical trial
Leebeek F. W. G. - Use of double virus-inactivated factor VIII concentrate (Immunate®) as treatment of von Willebrand disease
Leeming D. - A multicentre assessment of the endogenous thrombin potential using a continuous monitoring amidolytic technique
Lees S. - Population-based study of acquired hemophilia A
Leeuwenkamp O. R. - The prevalence and prognostic importance of elevated cardiac troponins in patients with acute submassive pulmonary embolism
Leftheriotis G. - Diagnosing pulmonary embolism with clinical assessment, d-dimer, venous ultrasound and helical computed tomography: a multicenter management study
Legani C. - Risk for recurrent venous thromboembolism among patients with severe inherited thrombophilia
Legault K. J. - Fibrinolysis within the procoagulant VX-2 tumor of rabbit lungs in vivo: Anti-angiogenic behavior of fibrin(ogen) degradation products
Legemate D. - Tissue factor (TF) and high-sensitivity CRP (HS-CRP) in patients with peripheral arterial disease (PAD) undergoing peripheral bypass surgery or angioplasty: a retrospective study
Legendre P. - Platelet translocation on von Willebrand factor is inhibited by RGDS peptide at high shear rate
  - Activation of pp125FAK by type 2B recombinant von Willebrand factor binding to platelet GPIb at high shear rate occurs independently of aIIb3 engagement
  - Specific interaction of the proteolytic SPII fragment of von Willebrand factor with fibrin
Léger P. - In terms of clinical impact, thromboplastins with an ISI close to 1 yield better results than thromboplastins with an ISI close to 2, in an external quality control campaign
Léger PH. - Bilateral deep-vein thrombosis and cancer: prospective study of 103 patients
Legnani C. - Risk of recurrence of venous thromboembolism (VTE) and high factor VIII plasma levels
  - Emotional impact of testing for inherited thrombophilia
Legnani C. - Thrombophilia and residual vein thrombosis are independent risk factors for recurrent venous thromboembolism
  - D-dimer and residual vein thrombosis assessed at 3 months after anti-coagulation withdrawal are independent risk factors for recurrent venous thromboembolism
Legnani G. - Genetic variants of CYP2C9 cytochrome do not account for high intraindividual variability of patients in their response to oral anti-coagulants (OA): a collaborative controlled study
Legnani C. - The risk of recurrence after a first episode of venous thromboembolism in cancer patients
  - Venous thromboembolic complications in patients with multiple myeloma treated with thalidomide:prophylatic effect of fixed dose Wafarin L
  - Markers of inflammation, d-dimer and recurrences after a first episode of venous thromboembolism
  - Comparative evaluation of a new automated latex agglutination d-dimer assay for exclusion of deep vein thrombosis
Legrand C. - Role of the affinity state of the a IIbb 3 receptor for fibrinogen in the formation and reversibility of model particle and platelet aggregation in shear
  - Primordial role of the P2Y12 ADP receptor in different phases of platelet–collagen interactions
  - Platelet aggregates modulate the adhesion of breast adenocarcinoma cells (MDA-MB-231) to endothelial cells and their matrix in whole blood and under flow conditions
Legrand E. - Human endothelial cells synthesize Protein Z
Lehnerer M. - A novel recombinant factor VIII produced by a human cell line functionally restores coagulation deficits in a mouse model of hemophilia A
Lehnigk U. - Expression and function of platelet glycoproteins in newborns and adults
Lehot J. J. - Anti-thrombotic treatment after coronary artery bypass graft surgery (CABGS):economic consequence of a change in regimen
Lehr S. - Is inflammation involved in the development of thrombosis in patients with the lupus anticoagulant?
  - C-reactive protein in patients with venous thromboembolism
  - IgG-antibodies (IgG-Ab) against beta-2-glycoprotein I (b2-GPI) are associated with an increased risk for thrombotic events (TE) in patients (pts) with the lupus anticoagulant (LA)
Leibach L. - Efficacy and safety of low dose vitamin K in outpatient management of patients with an INR > 10
Leidy N. K. - Health-related quality of life in adults with hemophilia: the patient perspective
Leijte A. - Effect of hyperhomocysteinemia on coagulation activation and endothelial cell activation
Leis L. A. - P38 MAP kinase is rapidly phosphorylated via agonist-specific pathways in human and dog platelets, but its activation is not causally linked to secretion
  - Experimental studies of anorectic drug cardiovascular toxicity: oral fenfluramine decreases dog platelet serotonin uptake and content, elevates plasma serotonin and causes mild mitral valve regurgitation
Leissinger C. - Prophylaxis Study in Inhibitor Patients
  - Pilot introduction study of a needleless transfer device (BAXJECT) for reconstitution of Factor VIII concentrates for infusion
Leitinger N. - Oxidized phospholipids inhibit action of endotoxin in vitro and in vivo
  - Oxidized phospholipids induce the human heme oxygenase-1 via CREB: a feedback mechanism in inflammatory disorders
  - Oxidized phospholipids induce proatherogenic genes in murine carotid arteries
Leivada A. - Early therapeutic splenectomy may reduce morbidity and management costs in selected resistant or relapsing cases of TTP/HUS
Leizorovicz A. - Epidemiology of postoperative venous thromboembolism in Asian countries: results of the SMART study
Leizorovicz A. - How should we prevent VTE in medical patients?
Leizorovicz A. - A randomized placebo controlled trial of dalteparin for the prevention of venous thromboembolism in 3706 acutely Ill medical patients: the PREVENT medical thromboprophylaxis study
  - A systematic review of the accuracy of ultrasound in the diagnosis of asymptomatic deep venous thrombosis: preliminary results
Leizoroviscz A. - Factors predicting venous thrombotic complications after superficial–vein thrombosis
Lekakul Y. - The use of recombinant activated factor VII for controlling life-threatening bleeding in dengue shock syndrome
Lekatsas J. - C-reactive protein: a link between inflammation and thrombosis formation in patients with unstable angina?
Lekehal M. - The thrombin potential in contrast to clotting times is only slightly modified after uncomplicated heart valve replacement in adults
Lemarié E. - Quantitative evaluation of TFPI-2 and MMP-9 expression in nonsmall cell lung cancer
Lembrez N. - Role of NADPH oxidase on mechanisms implicated in anoxia/reoxygenation-induced leukocyte adhesion to HUVECs
Lemke G. - Deficiency in one Gas6 receptor (Axl, Sky or Mer) protects mice against thrombosis because of a platelet dysfunction
Lemmens W. - Preconceptional, gestational and puerperal low anti-annexin A5 antibody levels in women who develop pre-eclampsia
Lemoine N. R. - Low-molecular weight heparin therapy and survival in patients with malignant disease
Lenain N. - A key role of the fast ATP-gated P2X1 cation channel in the thrombosis of small arteries in vivo
  - A key role of the fast ATP-gated P2 X 1 cation channel in the thrombosis of small arteries in vivo
Lenain N. - The role of the P2Y1, P2Y12, and P2X1 platelet receptors in a laser-induced model of arterial thrombosis in vivo
Lenk H. - The development of inhibitors directed against factor VIII after continuous infusion of factor VIII concentrates in patients with hemophilia A
Lennemann K. - New mutations in the fibrinogen genes of patients with dys, hypo- or fibrinogenemia
Lennon L. - Associations of hemostatic and inflammatory variables with prevalent myocardial infarction, angina and stroke in British men: British Regional Heart Study
Lenormand B. - Hypercoagulability in sickle cell disease: increased monocyte tissue factor expression and increased erythrocyte microparticles expressing phosphatidyl serine
Lens D. - Association between recurrent pregnancy loss and prothrombotic gene polymorphisms
Lensen R. P. M. - Linkage analysis of factor VIII and von Willebrand factor loci as quantitative trait loci
Lensing A. W. A. - Potential reversal agents for the long-acting pentasaccharide idraparinux
  - Fondaparinux vs. placebo for the prevention of venous thromboembolism in acutely ill medical patients (artemis)
  - Subsequent diagnosis of malignancy in patients presenting with an idiopathic venous thromboembolism – a number needed to screen and decision analysis based on the results of a prospective study
Lensing A. W. A. - Symptomatic chronic thromboembolic pulmonary hypertension after symptomatic pulmonary embolism: incidence and risk factors: a long-term follow-up study
Lensing A. W. A. - Below-knee elastic compression stockings for prevention of the post–thrombotic syndrome in patients with proximal-vein thrombosis: a prospective controlled randomized study
  - Compression ultrasound in diagnosis of asymptomatic deep venous thrombosis
  - The long-term clinical course of acute deep vein thrombosis of the arm: a prospective cohort study
  - Atherosclerosis as a potential risk factor of venous thrombosis
Lenti L. - Antioxidant effect of wine in human: role of polyphenols
Lenti M. - New risk factors for coronary artery disease: the endothelial nitric oxide synthase polymorphisms
Lenti L. - Enhanced TNF-a and oxidative stress in patients with heart failure: effect of TNF-a on platelet O2 production
Lenti M. - Optimization of human 14 000 oligonucleotide-microarrays and study design for the evaluation of gene expression profiling in cardiovascular diseases
  - Increased lipoprotein(a) levels as an independent risk factor for idiopathic and recurrent venous thrombosis
Lenti L. - Increased platelet superoxide anion production in patients with hypertension: role of AT1 receptors
Lenting P. J. - An in vivo model to study von Willebrand factor (VWF) clearance: fundamental aspects and application to the Arg1205His Vicenza mutation
Lenting P. J. - Increased metastatic potential of tumor cells in von Willebrand factor (VWF)-deficient mice
  - LDL-receptor related protein (LRP) interacts with leukocyte integrin CD11b/CD18: a novel pathway in inflammatory regulation?
  - Dimers of b2-glycoprotein I increase platelet deposition to collagen via interaction with phospholipids and the apolipoprotein E receptor 2: an explanation for arterial thrombosis in the anti-phospholipid syndrome
  - Platelet sensitization is mediated by Apolipoprotein E Receptor 2
  - Factor VIII – factor IX interactions probed by chimeric factor VIII/V variants: complex assembly and cofactor function involve different residues within the A3 domain region 1803–1818
  - Role of factor IX surface loop 342–347 in factor VIII-mediated enhancement of catalytic activity
  - Binding of b2-glycoprotein I and dimeric b2-glycoprotein I to members of the low-density lipoprotein receptor superfamily: implications for the anti-phospholipid syndrome
Lentz B. R. - Efficient human thrombin generation requires molecular phosphatidylserine and not a membrane surface
Lentz S. R. - Effect of mechanical ventilation on carotid artery thrombosis induced by photochemical injury in mice
Lentz B. R. - Water soluble phosphatidylserine (C6PS) induces bovine factor Xa structural change and dimerization; do factor Xa dimers have a physiological role?
Lentz B. R. - A phosphatidylserine binding site distinct from the C2 domain membrane attachment site regulates the assembly and activity of the human prothrombinase
Lentz S. - Role of the FcR gamma chain in collagen-induced platelet procoagulant activity
Lentze M. J. - Treatment of thrombotic complications and prophylactic use of protein C concentrate in two homozygous protein C deficient patients during surgery
Lenzi T. J. - Intrauterine growth retardation and recurrent pregnancy loss associated with prothrombin gene variants 20221C > T and 20209C > T
Leo L. - Role of the FcR gamma chain in collagen-induced platelet procoagulant activity
Leon C. - The role of the P2Y1, P2Y12, and P2X1 platelet receptors in a laser-induced model of arterial thrombosis in vivo
Leonard D. G. B. - A phase I/II trial of AAV-mediated, liver-directed gene transfer for hemophilia B
Leonardi-Bee J. - The effects of three anti-platelet drugs (aspirin, clopidogrel, dipyridamole) given singly or together on platelet and leukocyte function in healthy subjects and patients with previous ischemic stroke
Leone G. - Risk for recurrent venous thromboembolism among patients with severe inherited thrombophilia
  - Risk for venous thromboembolism among younger or older carriers of inherited thrombophilia
  - Risk for recurrent venous thromboembolism after a first superficial vein thrombosis among carriers of inherited thrombophilia
Leone T. - Risk for venous thrombosis in unusual sites associated with inherited thrombophilia: analysis of 133 patients
Leone G. - Inherited thrombophilia and associated risk for unexplained fetal loss
Lepäntalo A. - Inhibition of P2Y12-receptor in vivo and in vitro in patients undergoing elective percutaneous coronary intervention (PCI)
Lepape M. T. - Lack of correlation between HPA1 polymorphism and ADP induced platelet activation: study of a large cohort of normal subjects
Leprotti C. - Venice DVT
Leroux B. - Platelet function peculiarities throughout childhood: a flow cytometric study from healthy premature new-borns up to 15-year-old-children
Leschnik B. - Hemostatic risk factors, metabolic control, and microalbuminuria in diabetes mellitus type 1
Lester W. A. - A common mutation 4247T ® A (I1416N) causing type 2M von Willebrand disease in patients from three unrelated families previously diagnosed as severe type 1 VWD
  - Evaluation of a protein truncation test (PTT) for mutation detection in von Willebrand disease
Lester Z. - Dramatic improvement in the care and management of patients with DVT in a large UK hospital
Lester W. A. - Inherited and de novo von Willebrand disease ‘Vicenza’ in UK families with the R1205H mutation
Lester W. - Mutation analysis in type 1 von Willebrand disease patients entered in the multicenter MCMDM-1VWD study
Letellier P. - Acquired von Willebrand Syndrome: four cases associated with monoclonal gammopathy
Lethagen S. - A comparative in vitro evaluation of seven von Willebrand factor concentrates
Lethagen S. - Molecular and clinical markers for the diagnosis and management of type 1 von Willebrand's disease (VWD): The progress of a European collaboration
  - Mutation analysis in type 1 von Willebrand disease patients entered in the multicenter MCMDM-1VWD study
  - Sensitivity and specificity of PFA-100® vs. bleeding time in the diagnosis of type 1 von Willebrand disease (VWD)
Lethagen S. R. - Treatment of patients with VWD requiring elective surgery with a pasteurized von Willebrand Factor/FVIII concentrate (Haemate®P) – the use of a PK-guided approach
Lethagen S. - Evaluation of an automated assay for rapid analysis of von Willebrand ristocetin cofactor activity
  - An improved multimeric analysis identifies a subgroup of patients with Type 1 von Willebrand disease characterized by reduced VWF:RCo/Ag ratio
  - Comparison of hemorrhagic symptoms in obligatory carriers of type 1 and type 3 von willebrand disease (VWD): results from a collaborative, international, multicenter study
  - In vitro expression of 4 novel mutations identified in type 1 von Willebrand disease patients
  - Co-segregation of Von Willebrands disease type 1 phenotype and Von Willebrand factor gene haplotypes: first results from the multicenter study molecular and clinical markers for the diagnosis and management of type 1 Von Willebrands disease
  - The molecular background to von Willebrand disease type 1 in Sweden
  - Evaluation of a new quantitative, rapid test (VWF-LIA) for the diagnosis of type 1 VWD
  - Clinical presentation of type 1 von Willebrand disease (VWD) in obligatory carriers: final results from a collaborative, international, multicenter study
Leumas J. - The Rapidpoint™ ENOX point-of-care test has strong correlation with anti-Xa levels for detecting the anti-coagulant effects of enoxaparin
Leung L. - Roles of low specificity and cofactor interaction sites on thrombin during factor XIII activation: competition for cofactor sites on thrombin determines its fate
Leung L. L. K. - Quantitative transcript profiling and novel gene identification of vascular endothelial cell subtypes by serial analysis of gene expression (SAGE)
  - Factor XI-activation by thrombin on activated platelets requires both anion binding exosites I and II
Leung R. - Procoagulant surface expression on activated human platelets persists despite increased aminophospholipid translocase activity
Leung L. - Understanding thrombin
Leung L. L. K. - Role of surface amino acid residues in thrombin essential for inhibition by antithrombin, heparin cofactor II and protein C inhibitor
  - Activated TAFIa down-regulates the pro-inflammatory activity of thrombin cleaved osteopontin
Leurs J. - Carboxypeptidase U (TAFIa) prevents fibrinolysis from proceeding into the propagation phase through a threshold-dependent mechanism
Levels J. H. M. - Alterations in lipoprotein homeostasis during experimental and clinical sepsis in primates
Levels H. - A proteomic approach to identify plasma lipoprotein-associated proteins with a potential role in atherothrombosis
Lever R. - Platelet depletion abolishes eosinophil recruitment to the lungs and tissue remodelling in an allergic asthma model in mice
Levesque H. - Bilateral deep-vein thrombosis and cancer: prospective study of 103 patients
  - Hypercoagulability in sickle cell disease: increased monocyte tissue factor expression and increased erythrocyte microparticles expressing phosphatidyl serine
  - Prethrombotic biological markers in congenital thrombophilic patients. Preliminary results of a randomized long-term secondary prophylaxis study using warfarin and comparing two INR target ranges
  - Frequency and effects of cytochrome P450 2C9 polymorphisms in 61 patients treated by warfarin
  - Thrombophilic risk factors and idiopathic sudden sensorineural hearing loss
Levi M. M. - Age and first INR after standard initiation of oral anti-coagulant therapy with acenocoumarol predict the maintenance dosage
Levi M. - Recombinant factor VIIa reverses the anticoagulant effect of the long-acting pentasaccharide idraparinux in healthy volunteers
  - Prospective assessment of the diagnostic accuracy of the ISTH criteria for the diagnosis of DIC
Levi R. - CD39 ecto-nucleotidase activity (metabolizing ATP to ADP to AMP) constitutes a homeostatic mechanism for control of platelet reactivity, depending on the ratio of ADPase to ATPase activity. Results from patients with coronary artery disease
Levi M. - Inhibition of plasmin activity by tranexamic acid does not influence inflammatory pathways during human endotoxemia
  - Optimal intensity of oral anti-coagulant therapy in patients with mechanical heart valves
  - Clopidogrel suppresses rebound coagulation after discontinuation of enoxaparin treatment in patients with acute coronary syndromes
Levine M. N. - Long-term treatment with dalteparin low-molecular-weight heparin (LMWH) may improve survival in patients with nonmetastatic malignancy and venous thromboembolism (VTE)
Levine M. - How should we treat VTE in cancer patients
Levine M. N. - Long-term treatment with dalteparin low-molecular-weight heparin (LMWH) is more effective than oral anticoagulant (OA) therapy in cancer patients with venous thromboembolism (VTE)
  - Venous thrombosis in cancer patients: insights from the FRONTLINE survey
  - Low-molecular weight heparin therapy and survival in patients with malignant disease
Levine M. N. - From Trousseau to targeted therapy: new insights and innovations in thrombosis and cancer
Levi-Setti P. - Embryo implantation after assisted reproductive procedures and maternal thrombophilia
Levy G. - ADAMTS13 mutations identified in familial TTP patients result in loss of VWF-cleaving protease activity
Levy S. E. - Chronic paclitaxel exposure increases human endothelial expression of plasminogen activator inhibitor-1, tissue-type plasminogen activator and tissue inhibitor of metalloproteinase-1
Lewandowski K. - Antiphospholipid antibodies in patients diagnosed for thrombophilia
Lewandowski L. - High frequency of combined genetic prothrombotic defects in young patients with ischemic stroke
Lewandowski K. - Thrombin activable fibrinolysis inhibitior (TAFI) in patients with obesity
Lewis R. R. - Recognized and unrecognized clinical venous thromboembolism (VTE) after acute ischemic stroke (AIS): a prospective study using magnetic resonance direct thrombus imaging (MRDTI)
Lewis B. - Argatroban in HIT type II: clinical experience - trials and practice
Lewis R. R. - Performance characteristics of the VIDAS and IL test d-dimer (d-d) assays as exclusionary tests for venous thromboembolism (VTE) after acute ischemic stroke (AIS)
Lewis K. B. - CTRP1 – a vascular wall protein that can prevent platelet thrombosis without causing bleeding
Lewis B. E. - The predictors of clinical outcome in patients with heparin-induced thombocytopenia
Lewis S. - Factor X Cardiff and Factor X Newcastle: Two new FX mutations associated with low activity and antigen levels
Lewis H. - Bleeding in patients with factor XII deficiency may relate to concomitant platelet function disorders if von Willebrand's disease is excluded
Lewis R. K. - Factors that influence the prescribing of low-molecular-weight heparins (LMWHs) in community hospitals: opinions of physicians, clinical pharmacists, and formulary committee members
Lewis B. - Argatroban anticoagulation inhibits thrombin generation and its rebound during percutaneous interventional procedures
Lewis D. R. - A prospective randomized trial of anti-platelet therapies in patients with carotid artery disease (preliminary results)
Lewis B. - Percutaneous coronary interventions: is there a place for Argatroban
Lewis K. B. - Cross–species interactions of FXIII and fibrinogen
Lewis D. A. - Inhibition of factor VIII binding to phospholipids by single-chain variable domain fragments indicates that F2200 plays a more important role than M2199 in membrane-binding
Lewis R. R. - The relationship between acute ischemic stroke (AIS) per se and plasma D-D (D-D) levels
Lewis B. - Plasma procarboxypeptidase U is up-regulated in patients undergoing percutaneous intervention: effects of anticoagulant dosage of low molecular weight heparins
  - Case study on HIT
  - Elevated soluble thrombomodulin levels in patients with acute coronary syndrome: down-regulation by anticoagulant dosage of low molecular weight heparins
Lewis H. - Peri-operative bleeding in patients with Pseudomyxoma peritonei appears to relate to trauma induced hypofibrinogenemia
  - TAFI antigen levels in local hemophilia A and vWD population
Lewis R. R. - The relationship between plasma D-dimers (D-d) and thrombus load in patients with deep vein thrombosis (DVT) after acute ischaemic stroke (AIS): a prospective study using magnetic resonance direct thrombus imaging (MRDTI)
Lewis B. E. - Platelet and inflammatory changes induced by angioplasty and brachytherapy
Lewis K. B. - Agreement between FXIII activity assays and calibrator plasma pools: the need for a FXIII reference standard with regulatory recognition
Leya F. - Platelet and inflammatory changes induced by angioplasty and brachytherapy
  - Elevated soluble thrombomodulin levels in patients with acute coronary syndrome: down-regulation by anticoagulant dosage of low molecular weight heparins
  - Plasma procarboxypeptidase U is up-regulated in patients undergoing percutaneous intervention: effects of anticoagulant dosage of low molecular weight heparins
  - Argatroban anticoagulation inhibits thrombin generation and its rebound during percutaneous interventional procedures
Leyte A. - Endothelial cell and monocyte-derived microparticles in severe dengue virus infections
Leyte A. - A two-stage thrombophilia screening protocol: more efficient use of laboratory tests
Leytin V. - Extension of human platelet storage up to 7–8 days does not reduce their in vivo viability in a rabbit model
  - Flow cytometric evaluation of glycoprotein Iba on the platelet surface in vitro can predict post-transfusion viability of stored platelet concentrates
Li F. - A single point mutation of asparagine 511 to serine is responsible for the increased rate of cleavage of high molecular weight in Lewis rat, which is genetically susceptible to inflammatory stimuli
Li R. - The clinical relevance of anti-b2-GP1 antibodies assays in the presence of antiphospholipid antibodies and/or lupus anticoagulant
Li H. - Inhibition of angiogenesis by statins: a possible contribution for the protection of the vascular risk in atherosclerotic patients
  - The anti-angiogenic effect of endostatin is associated to a direct effect on the tumor growth in colon cancer
Li J. Z. - The study on phenotype and genotype of Protein C in a Chinese family with hereditary Protein C deficiency
Li N. - Enhanced platelet and leukocyte activation by strenuous exercise in type I diabetes mellitus
Li Y. M. - Inhibitory effects of andrographolide on lipopolysaccharide-induced tissue factor expression in human monocytic THP-1 cells
Li R. - Activation of the platelet integrin aIIbb3 by thermodynamic modulation of transmembrane helix associations
Li W. - Activation of the platelet integrin aIIbb3 by thermodynamic modulation of transmembrane helix associations
Li N. - Platelet function and inflammatory markers in patients with type 1 diabetes with and without microvascular complications
  - Enhanced leukocyte-platelet cross-talk in type 1 diabetes mellitus
Li A. - Spinal cord vascular malformations: imaging and endovascular treatment
Li Z. - Biphasic human platelet response to cGMP mediated via distinct signaling pathways: a predominant role for cAMP-dependent protein kinase in the cGMP-induced platelet inhibition and phosphorylation of vasodilator-stimulated phosphoprotein
Li N. - Platelet-leukocyte aggregation under shear stress: Differential involvement of selectins and integrins
Li J. H. - Biochemical, immunologic and computer-modeling evidence localizing the mAb 7E3 Epitope on aIIbb3
Li Z. Y. - Thrombotic thrombocytopenic purpura in a patient with acquired vWF protease (ADAMTS13) deficiency was heralded by variable stimuli and lacked a good correlation between platelet counts and vWF protease levels
Li X. - Studies of the relationship between elevated factor VIII level and ischemic stroke in China
Li X. F. - Effects of adrenaline and noradrenaline on the expression of tissue factor in endothelial cells
Li N. - Acute hyperglycemia enhances platelet secretion but not platelet aggregation
Li N. - Clopidogrel treatment reduces platelet activity in vivo, but does not counteract exercise-induced platelet activation
  - Clopidogrel treatment provides limited protection against exercise-induced platelet-leukocyte conjugation
Li X. - Hemophilia as a model for analysis of human germ-line mutagenesis: frequent mosacism and low male to female sex ratio for G:C®A:T nonCpG transitions and the first observation of a nucleotide bi-mutation are consistent with effects in early embryogenesis
Li J. C. - Determinations of plasma protein C activity and antigen levels in patients with liver diseases and its clinical significance
Liakopoulou-Kyriakidis M. - Synthetic tripeptides with specific inhibitory action against Gp-Ib glycoprotein
Lian E. C. - Thrombotic thrombocytopenic purpura in a patient with acquired vWF protease (ADAMTS13) deficiency was heralded by variable stimuli and lacked a good correlation between platelet counts and vWF protease levels
Liang O. D. - Regulation of neovascularization by a-defensins: a link between inflammation and angiogenesis
Liang A. - Development of small molecule compounds that inhibit PAI-1 activity in vitro and in vivo
Liang Z. - Examining the role of coagulation Factor VII using FVII-insufficient mice
Liang H. P. - Glycoprotein IX Asn45Ser: an ancestral mutation causing Bernard–Soulier syndrome in Europeans?
Liao C. H. - To evaluate the mechanism of neutrophil activation caused by a Cox-2 inhibitor-celecoxib
Liao P. - GH9001, a novel anti-thrombotic agent, is more effective than low-molecular-weight heparin, fondaparinux, or hirudin in rabbit models
  - Paradoxical effect of unfractionated heparin in combination with streptokinase on arterial recanalization
Liaw P. - Prognostic value of activated protein C levels in patients with severe sepsis
Liaw P. S. - Effects of full and partial substitution of the reactive center loop of alpha-1-proteinase inhibitor by that of heparin cofactor II on the inhibition of thrombin and activated protein C
Libby E. - Bridging therapy for mechanical heart valves: a model comparing unfractionated and low molecular weight heparin
Liboni A. - The G>T point mutation (Val34Leu) in the Factor XIII-A subunit gene in venous leg ulcers
Libourel E. J. - Increased risk for venous thromboembolism and myocardial infarction in family members of patients with prothrombin 20210 A mutation
  - The risk of pregnancy complications in women from families with thrombophilic defects
Libourel E. J. - Absolute risk of venous and arterial thromboembolism associated with mild hyperhomocysteinemia. Preliminary results of a family cohort study
Libourel E. J. - Venous and arterial thromboembolic risk in first degree family members of patients with elevated plasma levels of clotting factor VIII:c
Libourel E. - Absolute risk of venous thromboembolism (VTE) associated with a single or combined thrombophilic disorder. Preliminary results of a family cohort study
Libourel E. J. - Risk assessment of venous thromboembolism in pregnant women with factor V Leiden, prothrombin 20210 A mutation, elevated factor VIII levels or mild hyperhomocystinaemia
Librè L. - Oral anticoagulation telemedicine management system: the MC-SAT project
Lichy F. - Platelet function under aspirin, clopidogrel and both after ischemic stroke. A case-crossover study
Lideo L. - Anti-thrombin III levels in cynomolgus monkey recipients of a life-supporting porcine renal xenograft
Liebe V. - TIMP-1, TIMP-2 and MMP-9 as prognostic markers for clinical outcome in sepsis
  - MCP-1 as early marker for cell activation in septic patients
Liebe V. - The impact of factor V Leiden on the endothelial cytokine response to coagulation activation modulated by drotrecogin alfa (activated)
Liebe V. - Gene array transcript profiling of human endothelial cells identifies pathways regulated by Drotregocin alfa (activated)
  - Drotrecogin alfa (activated) inhibits degradation of cytokine-mRNA in an endothelial model of inflammation
Lieberman J. R. - Randomized, double-blind comparison of ximelagatran, an oral direct thrombin inhibitor, and warfarin to prevent venous thromboembolism (VTE) after total knee replacement (TKR)
Liesenfeld K. H. - Pharmacokinetics of BIBR 953 ZW, the active form of the oral direct thrombin inhibitor BIBR 1048, in patients undergoing hip replacement
  - The effect of BIBR 953 ZW, the active form of the oral direct thrombin inhibitor BIBR 1048, on the prolongation of aPTT and ECT in orthopedic patients: a population pharmacodynamic study
Liesner R. - Subcutaneous administration of protein C
  - Paradoxical association between the 316 Trp to Ser beta 2-glycoprotein I (beta2GPI) polymorphism and antibeta2GPI antibodies
  - The mechanism of platelet activation by recombinant factor VIIa in normal subjects and inherited hemostatic disorders – a whole blood, flow cytometric study
  - Transient lupus anti-coagulant directed against factor II
Liesum A. - Crystal structure of benzamidine-Factor VIIa/soluble tissue factor at 1.87 Å resolution: mapping of calcium, magnesium, sodium, and zinc sites in the Factor VIIa structure
Lietz H. - Activated clotting time guided dosage optimization of a low molecular weight heparin (tinzaparin) for surgical and interventional indications
  - Differential effects of unfractionated heparin and a low molecular weight heparin on anti-thrombin activity during the treatment of deep vein thrombosis
Lietz T. - Benefit and risk of heparin addition in maintaining peripheral venous catheters in neonates – a prospective, double-blind, placebo-controlled trial
Lietz H. - The irrelevance of International Normalized Ratio in the monitoring of anti-IIa and anti-Xa drugs
  - Malignancy-related thrombotic state is independent of defects in Factor V Leiden, prothrombin 20210 and MTHFR. Results from the initial profiling of cancer patients entering in a secondary prevention of venous thrombosis with enoxaparin (ONCENOX)
Lijima K. - Cys61stop is the first identified nonsense mutation in the factor X gene causing severe factor X deficiency in 3 unrelated homozygotes of Arab origin
Lijmer J. G. - Physicians' interpretation of ventilation-perfusion lung scans
Lijnen H. R. - Plasminogen activator inhibitor type I-deficient (PAI–/–) mice show an improved early host defense in E. coli peritonitis by a neutrophil-dependent mechanism
Lijnen H. - Deficiency of tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) impairs nutritionally induced obesity in mice
Likhanov I. - Disseminated intravascular coagulation in surgary
Likousi S. - Genetic risk factors in patients with myocardial infarction and correlation with echocardiographic study
Liliensiek B. - Long-term RAGE-mediated NF-kB activation in diabetic neuropathy and its role in loss of pain perception
Lillicrap D. - A type 2A (Group II) von Willebrand disease mutation (Leu1503Glu) associated with a minimal loss of high molecular weight von Willebrand factor (VWF) multimers
  - Treatment of severe canine hemophilia A by helper-dependent adenoviral-mediated gene therapy
  - An ancient von Willebrand Disease (VWD) mutation that associates with a common haplotype in ~14% of type 1 VWD patients
Lillicrap D. P. - The type 1/type 2M von Willebrand disease dilemma: findings from the Canadian Type 1 VWD study
  - Clear familial co-segregation of the type 1 von Willebrand disease phenotype and VWF haplotypes in the Canadian type 1 VWD study
Lillicrap D. - Gene therapy for hemophilia A with high-capacity adenoviral vectors: preclinical evaluation in hemophilic mice and dogs
Lillicrap D. P. - A new von Willebrand factor (VWF) online mutation and polymorphism database created on behalf of the ISTH VWF scientific and standardization committee (http://www.sheffield.ac.uk/vwf)
Lillicrap D. - Triple heterozygosity in the alphaIIb gene of a patient with Glanzmann thrombasthenia and platelets with a low alphaIIbbeta3 content
  - An in silico analysis of type 2 A von Willebrand disease mutations
  - Stability of dilutions of the recombinant factor VIII Kogenate FS stored in syringes
Lillicrap D. - Molecular genetics in hemophilia care
Lillicrap D. P. - The use of three hemophilia A mouse models to illustrate strain-specific differences in immune responses to FVIII protein replacement via protein infusion or adenoviral gene therapy
Lim B. C. B. - The effect of factor XIII Val34Leu on clot structure is fibrinogen dependent: evidence for a mechanism for cardioprotection of the Leu allele at high fibrinogen levels
  - Bb448 Lys/Lys variant alters coronary risk by an effect on fibrin structure/function due to conformational changes in fibrinogen
  - Cross-linking of fibrin by factor XIII and its effect on fibrin structure/function
Lim F. K. - Plasminogen activators, plasminogen activator inhibitor-1 and D-dimer levels in gynecological cancer
Lim L. - MTHFR C677T, Prothrombin G20210A and Factor V Leiden gene mutations in 80 patients with thromboembolic disease – the Singapore experience
Lima M. - Glanzmann thrombasthenia: a study of two Portuguese families and identification of a new homozygous C insertion in exon 10 of the GPIIIa
Lin S. W. - Expression of full-length recombinant factor VIII by doxycycline-controlled expression system
Lin X. - Interaction of the glycoprotein (GP) Ib-IX/V complex with the platelet collagen receptor GPVI
Lin J.-S. - INTERCEPT platelets, treated to inactivate pathogens, maintain hemostasis in thrombocytopenic patients: results of the SPRINT trial
Lin C. I. - Enhanced anti-angiogenesis ability of human kringle 1–5 domain via altering glycosylation sites and lysine binding properties
Lin F. - Human antibody against CD11b inhibits platelet–leukocyte interaction under high shear
Lin S. R. - Consequences of expression of hepsin in murine vascular systems
Lin S. W. - Consequences of expression of hepsin in murine vascular systems
Lin J. S. - A G-to-A mutation at -33 position in the promoter region of thrombomodulin gene and non-O blood group are associated with idiopathic venous thromboembolism: Taiwan Thrombophilia Study
Lin C. H. - A G-to-A mutation at -33 position in the promoter region of thrombomodulin gene and non-O blood group are associated with idiopathic venous thromboembolism: Taiwan Thrombophilia Study
Lin B. B. - A G-to-A mutation at -33 position in the promoter region of thrombomodulin gene and non-O blood group are associated with idiopathic venous thromboembolism: Taiwan Thrombophilia Study
Lin J. S. - Novel mutations in the factor X gene of a Taiwanese factor X-deficient patient
Lin S. W. - Novel mutations in the factor X gene of a Taiwanese factor X-deficient patient
Lin B. - Novel mutations in the factor X gene of a Taiwanese factor X-deficient patient
Linari S. - Comparison of hemorrhagic symptoms in obligatory carriers of type 1 and type 3 von willebrand disease (VWD): results from a collaborative, international, multicenter study
  - Clinical presentation of type 1 von Willebrand disease (VWD) in obligatory carriers: final results from a collaborative, international, multicenter study
Lincoff A. M. - Issues in monitoring direct thrombin inhibitors: comparison of a new, rapid Ecarin Clotting Time (ECT) test to activated clotting time (ACT) and anti-IIa assays
Lincz L. - Using ETP to predict which factor V Leiden heterozygotes will suffer from venous thrombo-embolism
Lind H. - Identification of a Factor IX cleaving protease and efficient reduction in a high purity Factor IX manufacturing process
Lindahl T. - Effects of anticoagulation, red blood cells and number of platelets on coagulation and clot elasticity measured by free oscillation rheometry
Lindahl T. L. - The relative importance of P2Y12/P2Y1 in thrombin/ADP-induced platelet activation and true synergistic action in-between inhibition of P2Y12 and P2Y1
  - Studies of blood coagulation and platelet function in thoracic surgery utilizing a point of care instrument, a free oscillation rheometer
Lindahl T. L. - The choice of tubes for blood collection – a plastic tube is not enough
Lindahl T. L. - Platelet-dependent coagulation amplification – role of tissue factor, factor XI and factor XII
Linde R. - Successful immune tolerance therapy in hemophilia B patients with fix: a new immunesuppressive strategy
  - A new protocol for inhibitor elimination in high responding hemophilia A patients
Lindgaard A. K. - Localized short-term myocardial ischemia causes massive coronary t-PA release
Lindhoff-Last E. - Routine homocysteine monitoring: stabilization of blood samples with fluoride
  - Detection of lupus anticoagulant: development of a new precise, sensitive and specific aPTT-based assay
Lindhoff-Last E. - The German thrombophilia-registry – first results: Women specific risk factors and venous thrombosis
  - Use of danaparoid sodium for continuous renal replacement therapy in intensive care patients
  - Lupus anticoagulant in systemic lupus erythematodes as risk factor for cryptogenic stroke
Lindhoff-Last E. - Risk factors and long-term follow-up of patients with the immune type of heparin induced thrombocytopenia
  - Safe anti-coagulation with danaparoid in pregnancy and lactation
  - Determination of heparin-platelet factor 4-IgG antibodies improves diagnosis of heparin-induced thrombocytopenia
  - Discontinuation of long-term oral anticoagulation (OAC): effects of concomitant administration of low-molecular weight heparin (LMWH) during the termination period – a prospective study
Lindhout T. - Specific interaction of the proteolytic SPII fragment of von Willebrand factor with fibrin
  - Platelet translocation on von Willebrand factor is inhibited by RGDS peptide at high shear rate
Lindhout J. - Binding of minute amounts of thrombin to GPIbalpha accelerates early platelet reactions, but not the platelet procoagulant response
Lindhout T. - Glycoprotein Ib and integrin a IIbb 3 contribute to GPVI-dependent vWF-collagen induced thrombus formation under flow
  - Interplay of glycoprotein Iba, integrin a2b1 and glycoprotein VI is required for human thrombus formation under flow
Lindley C. - Phase I study of a novel recombinant human soluble thrombomodulin, ART-123
Lindqvist P. G. - Coagulation factor V Leiden not increased in pregnancies complicated by abruptio placentae
Ling M. - Low detection rate of antibodies to nonfunctional epitopes on factor VIII in patients with hemophilia A and negative for inhibitors by Bethesda assay
Linkins L. A. - Use of different d-dimer levels to exclude venous thromboembolism depending on clinical pretest probability
Linkins L. - Ability of d-dimer to reduce the need for diagnostic imaging in patients with suspected pulmonary embolism: A randomized trial
Linthorst Homan M. W. - Long-term follow-up of patients with suspected deep vein thrombosis of the upper extremities: survival, risk factors and post–thrombotis syndrome
Linuma Y. - Coagulation factor XII activity, but not an associated common genetic polymorphism, is linked to recurrent miscarriage
Lip G. Y. H. - Endothelial damage in congestive heart failure (CHF): relationship between circulating endothelial cells (CECs) and von Willebrand factor (vWf)
Lip G. - Platelet P-selectin and target organ damage in hypertension
Lip G. Y. H. - Plasma P selectin must be measured in a citrated sample, not in serum
  - Abnormal thrombogenesis and endothelial damage/dysfunction is related to ‘nondipping’ pattern of nocturnal blood pressure in patients with coronary artery disease
  - Markers of inflammation, coagulation, endothelial damage and platelet activation in chronic renal disease
  - Impaired vascular function in hypertensive pregnancy
  - Which is the ideal plasma marker of endothelial damage/dysfunction in atrial fibrillation? A comparison of von Willebrand factor, E-selectin and soluble thrombomodulin
  - Abnormal thrombogenesis and endothelial damage/dysfunction is related to high pulse pressure in patients with coronary artery disease
Lip Y.H. - Prevention of stroke in atrial fibrillation - can we do better?
Lip G. Y. H. - Increased plasma tissue factor predicts adverse outcome in chronic heart failure
Lip G. Y. - Platelet activation and morphologic changes in hypertension
Lip G. Y. H. - Increased platelet adhesion in metastatic cancer
Lipari M. - Differential use of variable domains of D3H44 antibody in binding to tissue factor or to an anti-idiotypic antibody
  - Similar molecular interactions of factor VII and factor VIIa with the tissue factor region that allosterically regulates enzyme activity
Lira S. - Association of MTHFR and ACE gene polymorphisms in reflux associated with renal damage
Lischetzki G. - Thrombin generation in patients with stroke and elevated factor VIII levels
Lischetzki G. - Disseminated intravascular coagulation after varicella infection
Lisman T. - Recombinant factor VIIa restores adhesion and aggregation of a IIbb 3-deficient platelets in vitro
  - Enhancement of fibrinolytic potential in vitro by anticoagulant drugs targeting factor Xa, but not by those inhibiting thrombin or tissue factor
  - Enhanced procoagulant and antifibrinolytic potential of superactive variants of recombinant factor VIIa in plasma from patients with severe haemophilia A
Lite Investigators†  - Does rebound exist? A comparison of venous thromboembolic event rates in the post-treatment period for patients randomized to long-term low-molecular-weight heparin vs. warfarin sodium
Little M. - Human, conformation-specific, anti-GPIIb/IIIa (aIIbb3) single-chain antibodies generated by differential phage-display: a new generation of platelet inhibitors specific for the activated GPIIb/IIIa receptor?
Litvinov R. I. - Intermolecular forces of individual aIIbb3-fibrinogen and aVb3–osteopontin interactions on platelets
Litzler P. Y. - Human endothelial cells synthesize Protein Z
Liu Y. - Spinal cord vascular malformations: imaging and endovascular treatment
Liu D. - Activated protein C (APC) blocks p53-mediated apoptosis in ischemic human brain endothelium through endothelial protein C receptor (EPCR) and protease activated receptor 1 (PAR-1)
  - In vivo activated protein C (APC) neuroprotective activity involves endothelial protein C receptor (EPCR) and protease activated receptor 1 (PAR-1)
Liu Y. - Activated protein C as a proteolytically activable antioxidant, anticoagulant protein
Liu J. L. - aIIbb3 activation by botrocetin/vWf is ADP or TXA2 dependent and the resulting aIIbb3 outside-in signaling is the major trigger for subsequent granule release and TXA2 production
Liu G. - Identification of two novel point mutations in XIII A chain gene associated with congenital deficiency in a Chinese FXIII deficiency family
Liu L. - The study on phenotype and genotype of Protein C in a Chinese family with hereditary Protein C deficiency
Liu D. - Protein S confers neuronal protection during ischemic/hypoxic injury in mice
Liu P. - Overexpression of PAI-1 prevents abdominal aortic aneurysm development
Liu J. W. - High-level transgene expression of lentivirus-transduced human endothelial cells
Liu C. - Soluble platelet GPV: a new marker of thrombosis status
Liu D. - Recombinant murine activated protein C is neuroprotective in a murine ischemic stroke model
Livadiotaki A. - Correlation between SVCAM, SICAM plasma levels, the outcome of treadmill test and the systolic function of left ventricular (LV) in patients with coronary artery disease
  - Correlation SVCAM, SICAM plasma levels with the outcome of treadmill test and with attitudinal factors for coronary artery disease in patients without previous history of ischemic heart disease
  - Levels of plasma tissue activator plasminogen (tPA)- A useful marker in the differential diagnosis of chest pain (marker of plaque destabilization)
LIVE-ENOX INVESTIGATORS  - Efficacy and safety of two doses of enoxaparin in pregnant women with thrombophilia and recurrent pregnancy loss: the LIVE-ENOX study
Livingstone W. - NovoSeven does not produce an inflammatory reponse in a monocyte (THP-1) cell line or primary monocytes prestimulated with lipopolysaccharide
  - Thrombin causes an inflammatory cytokine response, which is inhibited by protein C, in both primary human monocytes and a monocyte (THP-1) cell line
Livnat T. - The severely impaired thrombin generation in 5 patients with severe factor XI deficiency and inhibitors is corrected in vitro by recombinant factor VIIa
Ljung R. - Paediatric haemophilia care: maximizing benefit, minimizing risk
Ljung R. C. R. - Why does the mutation G 17736A, Val 107 Val (silent), in the FIX gene cause hemophilia B in five Swedish families?
Llamas P. - Retrospective analysis of heritable thrombophilia in 90 children with Legg-Perthes disease
  - Hypercoagulability in cerebrovascular disease (CD): factor V Leiden, prothrombin G20210A and MTHFR C677T mutations and polymorphism in the annexin V kozac sequence
  - TNF-alpha promoter polymorphisms (-238 and -308) in patients with cerebrovascular disease
Llancheran A. - Plasminogen activators, plasminogen activator inhibitor-1 and D-dimer levels in gynecological cancer
Llanto L. - An interactive coagulation laboratory database benefiting the entire Hemophilia Center team
  - An improved simpler method for using the ReFacto™ Laboratory Standard in monitoring patients receiving BDDrFVIII
Llari I. - Assessment of platelet function during cardiopulmonary bypass using two new "point of care" devices
Llobet D. - Heritability of plasma antiphospholipid antibodies
Lloyd J. V. - Analysis of adult patients with von Willebrand disorder in South Australia
Lloyd A. - An economic evaluation of the costs and benefits of heparin rationalisation in a UK hospital
Lloyd J. - Laboratory diagnosis of von Willebrand Disorder: current and past practice in Australasia
  - Laboratory diagnosis of congenital thrombophilia: current and past practice in Australia
  - Laboratory assessment of acquired thrombophilia: current and past experience in Australasia with lupus anticoagulant (LA) and anti-cardiolipin antibody (ACA) testing
Lloyd J. V. - Low detection rate of antibodies to nonfunctional epitopes on factor VIII in patients with hemophilia A and negative for inhibitors by Bethesda assay
Lo Bue A. - Prevalence of haemostatic abnormalities in women with 3 or more implantation failures after in vitro fertilization
Lo Coco L. - Coagulation and complement inhibitors levels predict outcome in patients with severe sepsis
  - Chemotherapy-induced activation of hemostasis: the role of d-dimer
Loar P. - A program for the point of care testing (POCT) of the ACT to ensure safe control of heparinization in coronary angioplasty
Lobatto S. - The assessment of pretest probability in patients with suspected Deep-Vein Thrombosis is of great value in nonacademic teaching hospitals
Locadia M. - Relation between compliance and quality of treatment with vitamin K antagonists
  - The balance between the benefits and risks of treatment with vitamin K antagonists as perceived by patients
  - Patients' valuation of outcomes after venous thromboembolism
Locadia M. - The optimal duration of treatment with vitamin K antagonists in patients with a first episode of venous thromboembolism: a decision analytic approach
Locker G. - Treatment of adults with sepsis-induced coagulopathy and purpura fulminans with a plasma-derived protein C concentrate (Ceprotin®)
Lockett J. M. - Binding at two distinct exosites is required for activation of prothrombin by prothrombinase
Lockwood C. J. - Patients with adverse pregnancy outcome have lower levels of protein Z and protein S compared to patients with normal pregnancy outcome
  - Normal pregnancy is associated with decreased protein Z levels in the second and third trimesters compared to early pregnancy
Lodetti B. - Post-treatment of rats with simvastatin affords brain protection after focal ischemia as assessed by magnetic resonance imaging
  - Pentoxifylline prevents spontaneous brain ischemia in stroke-prone rats
Lodigiani C. - Embryo implantation after assisted reproductive procedures and maternal thrombophilia
Loeb M. - Prognostic value of activated protein C levels in patients with severe sepsis
Loeffler C. - The Jarvik 2000 artificial heart does not affect the activation status of platelets
Loetzer K. - Evidence for a functionally active protease-activated receptor-3 in human vascular smooth muscle cells
Loffredo L. - Fibrinogen as predictor of ischemic stroke in patients with nonvalvular atrial fibrillation
Loganath A. - Plasminogen activators, plasminogen activator inhibitor-1 and D-dimer levels in gynecological cancer
Loh Y. S. M. - Thrombotic events associated with the use of recombinant factor VIIa in a single institution: a role for caution
Lohmann S. M. - cGMP regulates thrombopoietin-induced CD34+ human stem cell proliferation and differentiation into megakaryocytes
Lohmann T. - The molecular mechanisms of platelet activation by prolactin
Loirat C. - Identification of seven new candidate mutations of ADAMTS13 gene in four French families related to congenital thrombotic thrombocytopenic purpura
Loisance D. - Aspirine resistance: a particularly high prevalence in patients after ventricular assist device implantation
Lollar P. - Characterization of high level expression sequence determinants within porcine factor VIII
  - Determination of free sulfhydryls in human factor VIII
Lollar P. - The antigenicity and immunogenicity of factor VIII
Lollike K. - In vitro effect of recombinant activated factor VII on thrombin generation and clot formation in blood from patients on vitamin K-antagonist therapy
Lombardi A. M. - Pseudogene coamplification mimicking a 14-bp deletion mutation in exon 5 of plasminogen gene: a methodological study
Lombardi A. - Evaluation of the fibrinolytic capacity before and after venous occlusion performed by serum d-dimer test after standardized coagulation
Lombardi A. - A frequent, apparently silent, polymorphism in prekallikrein (Fletcher factor) gene
Lombardi M. R. - Guidelines on management of nontherapeutic INRs: are really easy to apply in daily practice?
Lombardi R. - Concomitant activation of both the P2Y1-driven Gq and the P2Y12-driven Gi pathways is necessary for normal ADP-induced mobilization of platelet cytoplasmic Ca2+
  - Does plasma homocysteine influence the in vitro anti-coagulant response to activated Protein C?
Lombardi A. - Factor VII deficiency associated with severe hemophilia A
Loncar R. - Influence of anti-thrombin on platelet adhesion onto immobilized fibrinogen in simulated low flow in vitro system
London C. A. - Inhibition of retinal neovascularization in mice by antisense phosphorodiamidate morpholino oligomer against av integrins
London J. - Effect of hyperhomocysteinemia on paraoxonase activity
London F. S. - Thrombin-induced platelet signaling results in factor IXa binding to a subpopulation of platelets with low or absent GP1b antigen
Lonergan A. - Using ETP to predict which factor V Leiden heterozygotes will suffer from venous thrombo-embolism
Long G. - Quality of life and risk perception in a large family with heritable protein C deficiency (IPCI: International Protein C Investigation)
Long J. R. - Intrasvascular tissue factor procoagulant activity increases following joint replacement surgery
Long G. - Asymptomatic venous thrombosis is a frequent event in protein C deficiency: a systematic ultrasound assessment of 208 family members with the 3363-C insertion mutation (IPCI: International Protein C Investigation)
Long G. L. - Lower degree of protein C activation in protein C deficient individuals of a large kindred with type I PC deficiency, as measured by the level of APC-PCI complex
  - Heritability of clotting factors and the prothrombotic state: results from a large thrombophilic pedigree of French Canadian descent with Type I protein C deficiency
Longstaff C. - A survey of streptokinase products shows inconsistencies in the quality of thrombolytic products used worldwide
Longstaff C. - In vitro studies and computer simulations of plasminogen activation kinetics in fibrin clots
Loof A. - Evaluation of the surface-enhanced laser desorption/ionization time-of-flight mass spectrometry proteomic approach to determine Glanzmann Thrombasthenia in blood platelet lysates
Lopaciuk S. - Lupus anticoagulant and elevated anticardiolipin antibodies as risk factors for venous thromboembolism
Lopaciuk S. - Polymorphisms of the factor VII gene and ischemic stroke in young adults
Lopatina E. G. - Results of clinical use of ‘NovoSeven’ in Russia
  - Home treatment of patients with hemophilia in Russia
  - Comparative study of the effect of recombinant factor VIIa on clot growth and thrombin generation in normal and hemophilia A plasma in vitro
Lopez L. R. - Increased thrombin–anti-thrombin III levels in pre-eclampsia and disseminated intravascular coagulation
López J. - Peptides from the C-terminal regions of ADAMTS-13 specifically block cleavage of ultra-large von Willebrand factor multimers on the endothelial surface under flow
Lopez J. A. - Coexistence of multiple hemostatic genetic risk factors does not increase risk of coronary heart disease: The ARIC Study results
López M. A. - Temporary discontinuation of oral anti-coagulants in oncologic patients with mechanical heart valves
Lopez J. - Shear stress and the high molecular weight vWF multimers in thrombus formation
Lopez D. - IgG autoantibodies to OxLig-1/B2GPI complex are associated with arterial thrombosis in patients with anti-phospholipid syndrome
Lopez L. R. - IgG autoantibodies to OxLig-1/B2GPI complex are associated with arterial thrombosis in patients with anti-phospholipid syndrome
Lopez D. - IgG antiphosphatidylserine and anti-b2GPI are better predictors of arterial and venous thrombosis than anticardiolipin antibodies in antiphospholipid syndrome
Lopez L. R. - IgG antiphosphatidylserine and anti-b2GPI are better predictors of arterial and venous thrombosis than anticardiolipin antibodies in antiphospholipid syndrome
Lopez D. - OxiLDL/b2GPI complexes are frequent in SLE whereas autoantibodies to oxLig-1/b2GPI are more prevalent in patients with antiphospholipid syndrome
Lopez L. R. - OxiLDL/b2GPI complexes are frequent in SLE whereas autoantibodies to oxLig-1/b2GPI are more prevalent in patients with antiphospholipid syndrome
Lopez I. - Prospective study of the risk factors for the development of post–thrombotic syndrome after proximal deep vein thrombosis
Lopez J. A. - Identification of a binding site for glycoprotein Iba in the Apple 3 domain of factor XI
  - Tissue factor-bearing microparticles arise from monocyte lipid rafts and can fuse with activated platelets, consolidating all of the membrane-bound coagulation reactions on the platelet surface
López F. - Pharmacogenetics in the thrombolytic treatment of myocardial infarction: role of the FXIII V34L polymorphism
Lopez D. - Pro-atherogenic role for IgG antioxidised-low-density-lipoprotein-beta-2-glycoprotein-I complex in primary antiphospholipid syndrome
Lopez L. - Pro-atherogenic role for IgG antioxidised-low-density-lipoprotein-beta-2-glycoprotein-I complex in primary antiphospholipid syndrome
López M. F. - Detection of conformational transformation of antithrombin in blood by crossed immunoelectrophoresis: new application for a classical method. Effect of temperature in plasmatic antithrombin; role in senescence of antithrombin and thrombosis
Lopez M. L. - Massive life-threatening lung hemorrhage and successful treatment with recombinant human-activated FVIIa concentrates
Lopez M. - Characterization of the urinary metabolites of dipetarudin
Lopez Lira F. - Characterization of the specific interaction between plasminogen and b2-glycoprotein I
Lopez-Duarte M. - Successful use of recombinant FVIIa (Novoseven) for severe bleeding in a patient undergoing bone marrow transplantation refractory to standard hemostatic support
López-Fernández M. F. - Replacement therapy for surgery and delivery in three patients from a single family with R1374C type 2M von Willebrand disease (VWD): the role of PFA100 monitoring
López-Franco M. - Retrospective analysis of heritable thrombophilia in 90 children with Legg-Perthes disease
Lopez-Pedrera C. - Increased tissue factor expression in monocytes from patients with anti-phospholipid syndrome depends on NFkB activation
Lopez-Pedrera C. - A promising therapeutic strategy in acute promyelocytic leukemia (APL): disruption of MEK/ERK, arsenic and retinoids
Lopez-Saura P. - Gene transfer of naked plasmid DNA encoding VEGF121 leads to revascularization of ischemic tissue in animal models of vascular diseases
  - Gene transfer of naked plasmid DNA encoding VEGF121 leads to revascularization of ischemic tissue in animal models of vascular diseases
Lord S. T. - High resolution crystal structures of two variant fibrinogens suggest ‘B:b’ interactions are critical to normal polymerization
  - Investigation of residues in the fibrin(ogen) gamma chain involved in t-PA binding and plasminogen activation
  - Alteration of the KGD sequence in fibrinogen b-chain slowed platelet mediated clot retraction
Lord S. T. - Altered vascular remodeling in hyperfibrinogenemic mice
Lorenzet R. - Resveratol and quercetin inhibit tissue factor expression in vascular cells by preventing IkappaBalpha degradation and c-Rel/p65 activation
  - Tissue factor expression by human endothilial cells is down-regulated by antagonists of the renin-angiotensin system
  - Polymorphisms of the interleukin 1-b gene, inflammatory and hemostatic response and the risk of premature myocardial infarction
Lorenzo J. I. - Treatment with recombinant activated factor VII of intra-abdominal bleeding associated with disseminated intravascular coagulation caused by septic shock
Lorenzoni R. - Clopidogrel plus aspirin in the prevention of thromboembolism in cardioverted atrial fibrillation: results of the clopidogrel aspirin atrial fibrillation (CLAAF): a pilot study
Lorin J. - CD39 ecto-nucleotidase activity (metabolizing ATP to ADP to AMP) constitutes a homeostatic mechanism for control of platelet reactivity, depending on the ratio of ADPase to ATPase activity. Results from patients with coronary artery disease
Loriot M.-A - Variations of INR and Factor VII Level are linked to Cytochrome P450 2C9 genotype
Lorrain J. - Thrombolysis induced by streptokinase or recombinant plasminogen activator (rt-PA) is improved by SSR182289A, a direct orally active thrombin inhibitor, in rabbit models of thrombosis
Loscalzo J. - FXIII promotes endothelial cell migration, proliferation, and inhibits apoptosis
Lösche W. - Activated platelets and platelet-derived microvesicles (PMV) transfer tissue factor (TF) to monocytes but not to neutrophils
  - Oral infection as a risk factor of atherosclerosis: first results of an intervention study
Losert H. - High prevalence of aspirin resistance in patients with acute coronary syndromes
Loskutoff D. J. - Aging and obesity augment the stress-induced expression of tissue factor gene in the mouse
Losonczy G. - A novel mutation (1668delC) in the glycoprotein IIb (CD41) gene causing Glanzmann's thrombasthenia
Lotfi V. - Prenatal diagnosis of dysprothrombinemia in an Iranian family
Lotto V. - Low vitamin B6, markers of inflammation, and coronary artery disease
Loudon R. G. - The peptide LSARLAF directly induces a conformation change in the platelet integrin aIIbb3
Loughran T. - Treatment of myelodysplastic syndrome with arsenic trioxide (ATO): response in refractory, transfusion-dependent patients
Loulakis Z. - Comparison and diagnostic value of two different D-dimer methods in the clinical laboratory
Lounes K. - Fibrinogen binds to aIIbb3 through a composite site where the known g 400–411 sequence is complemented by residues located in the vicinity of the ‘a’ polymerization site
Lounes K. C. - Investigation of residues in the fibrin(ogen) gamma chain involved in t-PA binding and plasminogen activation
Lounes K. C. - Alteration of the KGD sequence in fibrinogen b-chain slowed platelet mediated clot retraction
Lounes K. C. - High resolution crystal structures of two variant fibrinogens suggest ‘B:b’ interactions are critical to normal polymerization
Lourenço D. M. - A transcobalamin gene polymorphism and the risk of deep venous thrombosis
  - Prothrombin mutation G20210A, and not factor V Leiden, is a significant risk factor for cerebral venous thrombosis in 27 Brazilian patients
  - Factor XIII (FXIII) Val34Leu, His95Arg and G30899A polymorphisms and the risk of deep venous thrombosis
  - A 23-bp insertion in the EPCR gene and the risk of venous thrombosis
Lourenssen G. J. A. C. M. - Long-term in vivo platelet presensitization may explain the mechanism of factor VIIa prophylaxis in factor VII-deficient patients
Lourenssen G. - The Nijmegen low-titer factor VIII inhibitor assay: a highly sensitive assay for the detection of low-titer factor VIII inhibitors
Lourés E. - Replacement therapy for surgery and delivery in three patients from a single family with R1374C type 2M von Willebrand disease (VWD): the role of PFA100 monitoring
Louwen F. - Favourable course of hemorrhagic complication in early pregnancy of a patient with congenital afibrinogenemia under replacemant therapy
Love B. - Effectiveness of polybrene neutralization of heparin and low-molecular weight heparin in plasma
Lovegrove J. L. - The inhibitory action of quercetin on GPVI-mediated platelet signaling and activation
Lovejoy A. - Paradoxical effect of Factor XIII replacement on clot initiation
Lovely R. S. - Inhibition of coagulation and thrombin-mediated platelet aggregation by plasmin-cleaved fibrinogen g'-chain carboxyl terminal peptide
Low J. - Detection of procoagulants with a more reliable nonactivated clotting test
  - Laboratory assessment of acquired thrombophilia: current and past experience in Australasia with lupus anticoagulant (LA) and anti-cardiolipin antibody (ACA) testing
Low J. - Diagnostic utility of Simplify d-dimer – a new d-dimer test for patients with suspected venous thromboembolism
Low J. - Laboratory diagnosis of congenital thrombophilia: current and past practice in Australia
  - Procoagulant phospholipid in blood normally associates mainly with cells or aggregates larger than microparticles or platelets
Low J. - An evaluation of preoperative hemostatic variables as risk factors for deep venous thrombosis after elective lower limb arthroplasty
Low V. - Low-molecular weight heparin therapy and survival in patients with malignant disease
Lowe G. - Is homocysteine an independent risk factor for myocardial infarction? Results from the Glasgow myocardial infarction study
  - Thrombophilia in pregnancy, combined oral contraceptives and hormone replacement therapy users: a systematic review
  - Associations of hemostatic and inflammatory variables with obesity and blood pressure in men and women aged 30–59 years: cross-sectional population survey
  - Screening for thrombophilia: an economic assessment
Lowe G. - Associations of hemostatic and inflammatory variables with prevalent myocardial infarction, angina and stroke in British men: British Regional Heart Study
Lowe G. - The risk of thromboembolism and the effectiveness of prophylactic treatment in thrombophilia patients undergoing major orthopaedic surgery: a systematic review
Lowe G. D. O. - Effect of bezafibrate on plasma homocysteine in men with lower extremity arterial disease
  - Coagulation activation markers in atrial fibrillation: dose-dependent correlation with warfarin therapy
  - Population prevalence of atrial fibrillation and factors associated with use of warfarin
Lowe G. - Effects of age, sex, and oral contraceptive use on hemostatic, fibrinolytic and inflammatory variables: cross-sectional population survey
Lowenhoff T. - Suppression of thrombin generation and fibrinolysis in patients with rheumatoid arthritis treated with anti-TNFa monoclonal antibody (Infliximab)
Lowry D. - Effects of clopidogrel-aspirin combination vs. aspirin alone on platelet aggregation and major receptor expression in patients with heart failure. For the plavix use for treatment of congestive heart failure (PLUTO-CHF) trial
Lowry D. R. - Platelet inhibition by valsartan and valeryl 4-hydroxy valsartan: a possible missing link to explain benefits of angiotensin II receptor blockers in patients after acute vascular events
Lowry P. J. - Evidence for a role of tachykinins in the regulation of human platelet activation
Loyau S. - Effect of apolipoprotein(a) on plasminogen activation-induced apoptosis of vascular smooth muscle cells
Lozano M.L. - Analysis of the HPS-1 gene in patients with single platelet dense-granule deficiency and mild bleeding diathesis
Lozano M. - Stored platelets contain residual amounts of tissue factor
Lu X. - Development of bifunctional inhibitors of both platelet aggregation and factor Xa
Lu D. - Development of bifunctional inhibitors of both platelet aggregation and factor Xa
Lu X. - Development of bifunctional inhibitors of both platelet aggregation and factor Xa
Lu L. - Evaluation of protein Z (PZ) and protein Z-dependent protease inhibitor (ZPI) plasma levels and the in vitro inhibition of activated factor X by PZ/ZPI in patients with autoimmune aPL
Lu H. - The anti-angiogenic effect of endostatin is associated to a direct effect on the tumor growth in colon cancer
Lu L. - Phosphoinositide 3-kinase beta (PI3Kb): a novel target for antithrombotic therapy
Lu S. - Interaction of the glycoprotein (GP) Ib-IX/V complex with the platelet collagen receptor GPVI
Lu G. - Competitive activation of IX and X by the extrinsic pathway. Studies of the differential regulation of enzyme and products by antithrombin III and tissue factor pathway inhibitor reveal that active IXa is a major reaction product of this pathway
Lu A. - Anti-thrombin III phenylalanines 122 and 121 contribute to its high affinity for heparin and conformational activation
  - Inflammatory modulation of alveolar coagulation inhibition in a mouse model of acute respiratory distress syndrome (ARDS)
Lu Y. - Thrombin generation after ischemic stroke: the hemostatic system activation study (HAS)
Lu X. - The influence of the substitution of arginine within the RGD tripeptide motif of dendroaspin on its activity as a potent inhibitor of platelet aggregation and cell adhesion
Lu D. - The influence of the substitution of arginine within the RGD tripeptide motif of dendroaspin on its activity as a potent inhibitor of platelet aggregation and cell adhesion
Lubenow N. - Anaphylactic reactions associated with lepirudin in patients with heparin-induced thrombocytopenia (HIT)
  - Cross-reactivity of anti-lepirudin antibodies from patients with heparin-induced thrombocytopenia with bivalirudin
Lubetsky A. - Cone and plate(let) analyzer as a diagnostic tool in various types of thrombotic thrombocytopenic purpura and haemolytic uremic syndrome
Luboshitz J. - Clot from platelet rich plasma promotes wound healing
Lucarelli G. - Platelet-derived nitric oxide (NO) is suppressed by hyperhomocysteinemia: a possible prothrombotic effect
Lucarini L. - Optimization of human 14 000 oligonucleotide-microarrays and study design for the evaluation of gene expression profiling in cardiovascular diseases
  - Cytokine gene expression and production in human LPS-stimulated mononuclear cells are inhibited by sulfated heparin-like semi-synthetic derivatives
Lucas C. - Tissue factor pathway in carotid atherosclerotic plaques: relationships with clinical patterns and risk factors
Lucas J. - Prospective study of the risk factors for the development of post–thrombotic syndrome after proximal deep vein thrombosis
Luddington R. - The use of corn trypsin inhibitor to reduce the effect of sample contact activation in assays utilizing low tissue factor
Luddington R. - Incidence of recurrent venous thromboembolism in relation to clinical and thrombophilic risk factors
Ludwig R. - P-selectin-dependent lung colonization of melanoma cells is targeted by heparin treatment
Ludwig K. - Correlation of parameters characterizing healthy newborns with cord blood concentration of thrombin activatable fibrinolysis inhibitor (TAFI)
Lugovskoy E. - Utilization of monoclonal antibodies for the quantification of molecular markers of hemostasis
Lugovskoy E. V. - New polymerization sites in the central and peripheral domains of human fibrin molecule
Lugovskoy E. - N-terminal disulfide knot of fibrin increases the accumulation of hyaluronic acid in the pericellular matrix of human umbilical vein endothelial cells
Lukas J. C. - Population pharmacokinetics of the ReFacto coagulation factor VIII in clinical hemophilia patients with HIV
Lukasik M. - High frequency of combined genetic prothrombotic defects in young patients with ischemic stroke
Luken B. M. - Novel approaches to determine the characteristics of ADAMTS13 inhibitors in patients with acquired TTP
Lund T. - The relationship between sh-CRP and reactivity of monocytes and various blood parameters known to play an important role in atherogenesis
  - Epinephrine promotes LPS-induced interleukin-8 (IL-8) production in whole blood through thromboxane A2
Lundholm C. - Platelets synthesize large amounts of PAI-1
Lundqvist G. - Spiral computed tomography has a higher sensitivity and specificity than d-dimer in the diagnosis of acute pulmonary embolism
  - A comparison of spiral computed tomography and latex agglutination D-dimer assay in acute pulmonary embolism using pulmonary arteriography as Gold Standard
Lundström T. - Extended secondary prevention with the oral direct thrombin inhibitor ximelagatran for 18 months after 6 months of anticoagulation in patients with venous thromboembolism: a randomized, placebo-controlled trial
Lunghi B. - Modulation of factor V levels in plasma by intragenic polymorphisms
Luni S. - The incidence of venous thromboembolism in homozygous or double heterozygous carriers of the factor V Leiden mutation, prothrombin 20210 A mutation and HR2 aplotype: interim report
  - The incidence of venous thromboembolism in carriers of single identified prothrombin G20210A: a retrospective cohort study
  - Correlation between internal carotid artery stenosis and hematological risk factors for thrombosis (CAST study): final results
Luo H. - Ultrasound improves myocardial perfusion in a canine model of myocardial infarction
Lupu C. - Cholesterol and caveolin modulate the cell surface distribution and activity of TFPI
Lupu F. - Cholesterol and caveolin modulate the cell surface distribution and activity of TFPI
Lupu F. - Trafficking and cell surface dynamics of tissue factor pathway inhibitor in living cells
Lupu C. - Trafficking and cell surface dynamics of tissue factor pathway inhibitor in living cells
Lusher J. - Comparison of hemorrhagic symptoms in obligatory carriers of type 1 and type 3 von willebrand disease (VWD): results from a collaborative, international, multicenter study
Lusher J. M. - An improved simpler method for using the ReFacto™ Laboratory Standard in monitoring patients receiving BDDrFVIII
Lusher J. - Clinical presentation of type 1 von Willebrand disease (VWD) in obligatory carriers: final results from a collaborative, international, multicenter study
Lusher J. M. - An interactive coagulation laboratory database benefiting the entire Hemophilia Center team
Lussana F. - Contribution of factor V deficiency to the thrombotic risk associated with factor V HR2
Luther T. - Microvesicle and platelet associated tissue factor promote initiation of coagulation
Lutters B. - Importance of beta-2 glycoprotein I in the lupus anticoagulant cofactor effect: a case report
Lutters B. C. H. - Binding of b2-glycoprotein I and dimeric b2-glycoprotein I to members of the low-density lipoprotein receptor superfamily: implications for the anti-phospholipid syndrome
Lutters B. C. H. - Dimerization of beta2-glycoprotein I is necessary for binding to and activation of endothelial cells
Lutters B. C. H. - Dimers of b2-glycoprotein I increase platelet deposition to collagen via interaction with phospholipids and the apolipoprotein E receptor 2: an explanation for arterial thrombosis in the anti-phospholipid syndrome
Lux P. - The presence of antiphospholipid antibodies is not related to increased levels of annexin A5 in plasma
Luxembourg B. - Routine homocysteine monitoring: stabilization of blood samples with fluoride
Luxembourg B. - The German thrombophilia-registry – first results: Women specific risk factors and venous thrombosis
Lv M. - Soluble platelet GPV: a new marker of thrombosis status
Ly L. - Effect of a RNA-thrombin aptamer on thrombin inhibition by antithrombin, heparin cofactor II and protein C inhibitor
  - Role of surface amino acid residues in thrombin essential for inhibition by antithrombin, heparin cofactor II and protein C inhibitor
Lyapin G. - Influence of heparin-like plant component on fibrinolysis
Lyapina I. N. - Influence of heparin-like plant component on fibrinolysis
Lyapina L. - Activation of anti-coagulating system by gelatin introduction to animals
Lyberg T. - Localized short-term myocardial ischemia causes massive coronary t-PA release
Lyengar S. - Single-dose use of recombinant factor VIIa (NovoSeven) for correction of hepatic-induced coagulopathies prior to minor, invasive procedures
Lyles D. S. - aIIbb3 integrin activation mechanisms – switchblade or scissors?
Lynch C. M. - Effect of mechanical ventilation on carotid artery thrombosis induced by photochemical injury in mice
Lynn R. - Thromboembolism in childhood: a prospective 2 years study in the United Kingdom (February 2001 – February 2003)
Lyons R. M. - Secondary prevention of venous thromboembolic events (VTE) in patients with active malignancy: a randomized study of enoxaparin sodium alone vs. initial enoxaparin sodium followed by warfarin for a 180-day period