FEBS Journal highly cited papers

Top cited FEBS Journal papers 2010-2011 (two years from publication period October 2008 – March 2009)

Post-ischemic brain damage: pathophysiology and role of inflammatory mediators
Amantea, D; Nappi, G;Bernardi, G; Bagetta, G; Corasaniti, MT
FEBS Journal 276, 13-26, January 2009

Diana Amantea obtained a PhD in Pharmacology from the Birmingham University, UK (2003) followed by an honorary lecturership. She has been Aggregate Professor in Pharmacology at the School of Pharmacy, University of Calabria (Italy) since 2005, and is leader of the research unit on stroke. She has contributed to the understanding of acute brain regional differential neuroinflammatory mechanisms in the course of stroke, and most recent discoveries in this field have been patented; this work will allow a transition of her research activity to translational research.

Ribonuclease H: the enzymes in eukaryotes
Cerritelli, SM; Crouch, RJ
FEBS Journal 276, 1494 - 1505, March 2009

Emerging pathways in genetic Parkinson's disease: Potential role of ceramide metabolism in Lewy body disease
Bras, J; Singleton, A; Cookson, MR; Hardy, J
FEBS Journal 275, 5767 - 5763, December 2008

Investigation of leucine-rich repeat kinase 2
Anand, VS; Reichling, LJ; Lipinski, K; Stochaj, W; Duan, WL; Kelleher, K; Pungaliya, P; Brown, EL; Reinhart, PH; Somberg, R; Hirst, WD; Riddle, SM; Braithwaite, SP
FEBS Journal 276, 466 - 478, January 2009

MicroRNAs - micro in size but macro in function
Singh, SK; Bhadra, MP; Girschick, HJ; Bhadra, U.
FEBS Journal 275, 4929 - 4944, October 2008

Dr. Sunit Kumar Singh completed his PhD degree at the University of Wuerzburg, Germany in the area of Molecular Infection Biology, and completed his postdoctoral training at the Department of Internal Medicine, Yale University, and the Department of Neurology, University of California, Davis Medical Centre, USA. He is currently leading a research group in the area of virology at the Centre for Cellular and Molecular Biology (CCMB), Hyderabad, India. He has several awards to his credit and he is also associated with a number of international journals as Associate Editor and Editorial Board Member.

Protein transport in organelles: Dual targeting of proteins to mitochondria and chloroplasts
Carrie, C; Giraud, E; Whelan, J
FEBS Journal 276, 1187 - 1195, March 2009

Jim Whelan obtained his BSc and PhD degrees from University College, Dublin, Ireland. He moved to the Australian National University and later the University of Western Australia.

His primary research interest is the study of mitochondrial biogenesis. This ranges from defining the switches that control gene expression for organelle proteins to the targeting of proteins to mitochondria and the mechanisms to avoid mis-sorting to chloroplasts.

Natural polyphenols as proteasome modulators and their role as anti-cancer compounds
Bonfili, L; Cecarini, V; Amici, M; Cuccioloni, M; Angeletti, M; Keller, JN; Eleuteri, AM.
FEBS Journal 275, 5512 - 5526, November 2008

ANNA MARIA ELEUTERI is an associate professor in Clinical Biochemistry and Molecular Biology at the University of Camerino.
She had a post doc position (1994-1996) at the Mount Sinai School of Medicine of New York, under the guidance of Prof. Marian Orlowski and, since then, her major research interest has focussed on the study of proteasomes modulation to understand the potential role of the complex on the onset of pathologies, like neurodegenerative and neoplastic diseases.

Autophagy inhibits reactive oxygen species- mediated apoptosis via activating p38-nuclear factor-kappa B survival pathways in oridonin- treated murine fibrosarcoma L929 cells
Cheng, Y; Qiu, F; Ye, YC; Guo, ZM; Tashiro, SI; Onodera, S; Ikejima, T
FEBS Journal 276, 1629 - 1640, March 2009

Takashi Ikejima was born in Okayama City in Japan in 1947, got Ph.D. in Developmental Biology at Tohoku University in Japan in 1978, moved to Harvard Medical School Dept. Anatomy and Tufts University Medical School. In 1996, he started study on anti-inflammatory effects of Traditional Chinese Medicine in Changchun, China. Now he is a Director of China-Japan Research Institute of Medical and Pharmaceutical Sciences at Shenyang Pharmaceutical University, specializing in apoptosis, autophagy and necroptosis.

SREBPs: physiology and pathophysiology of the SREBP family
Shimano, H
FEBS Journal 276, 616 - 621, February 2009

Professor Hitoshi Shimano, a Professor of Internal Medicine (Endocrinology and Metabolism Group) at the Graduate School of University of Tsukuba, received his M.D. and Ph.D. from the University of Tokyo in Japan. After working as a research fellow in the Goldstein, Brown Lab at UT Southwestern, he has been studying transcriptional regulation of fatty acid synthesis with patho-physiological links to metabolic and cardiovascular diseases at Tsukuba. He is also attempting to reveal upstream mechanisms of energy sensing and novel functions of tissue fatty acids in broader biology, including brain function.

Amyloid-beta protofibril levels correlate with spatial learning in Arctic Alzheimer's disease transgenic mice
Lord, A; Englund, H; Soderberg, L; Tucker, S; Clausen, F; Hillered, L; Gordon, M; Morgan, D; Lannfelt, L; Pettersson, FE; Nilsson, LNG
FEBS Journal 276, 995 - 1006, February 2009

Lars Nilsson is Associate Professor at the Department of Public Health & Caring Sciences, Uppsala University in Sweden, where he has been active as group leader since 2002. The objective of his research is to decipher mechanisms of amyloid formation and to develop therapeutics for Alzheimer’s disease, which involves modeling disease in transgenic mice.

Dynamic association of MLL1, H3K4 trimethylation with chromatin and Hox gene expression during the cell cycle
Mishra, BP; Ansari, KI; Mandal, SS
FEBS Journal 276, 1629 - 1640, March 2009

Subhrangsu Mandal is an Assistant Professor at the Department of Chemistry and Biochemistry, University of Texas at Arlington. He received his PhD from the Indian Institute of Science and pursued postdoctoral studies at the University of Alberta (Alberta Heritage Foundation for Medical Research postdoctoral fellow) and University of Medicine and Dentistry of New Jersey/HHMI. His current research interest is to explore the functions of histone modification in human gene regulation, steroid hormone signaling, endocrine disruption, epigenetics and disease.