Epidemiological and clinical characteristics of influenzaA (H1N1)V infection in Isfahan, Iran, JulyOctober2009

Abstract number: R2374

Babak A., Akhtar E., Fadaei Nobari R.

Objectives: Following the declaration by the World Health Organization (WHO) of human cases of infection with a new influenza A (H1N1) virus, the Iranian Ministry of Health (MoH) launched a system to monitor and report the presence of this new virus on 10 May 2009. Here we report the confirmed cases of this new virus identified in Isfahan, a province in Iran.

Methods: In a laboratory-based reporting system, the Provincial Health Centers were supplied by the MoH with case definition and patient information forms to be disseminated to all health care institutions in their province. Any person who fulfilled the case definition criteria was directed to one of the three designated health facilities that were prepared to receive suspected cases. The nasopharyngeal samples were sent to the National Influenza Reference Laboratory at Tehran school of Public Health in a viral transport medium (virocult, Medical wire & Equipment, UK) and were tested with the real time RT-PCR protocol and reagents supplied by the WHO.

Results: A total of 376 samples were taken from suspected cases between 1 July and 21 October 2009.50 from these samples were positive for influenza A (H1N1). The date of symptoms onset of the first confirmed case of pandemic H1N1 influenza was 13 July 2009. She had traveled to Mecca (Saudi Arabia) and had already become symptomatic while staying there. 58% of the cases were female. The median age was 27 years (range: 10–75 years). The majority of cases (34%) were from 25 to 29 years old. 9 of them (18%) were hospitalized. 58% of the patients had a travel history to other affected areas. Most travel-associated cases had been returning travelers from Saudi Arabia (55.2%), followed by Malaysia (17.24%).12.24% had close-contact with other patients. The Median duration between developing symptoms and referring to health centers was 3 days (range: 0–9 days). Fever was the most common symptom, presented in 95.9% of the cases, followed by cough (85.7%) and myalgia (77.5%). One death was reported.

Conclusion: Influenza A (H1N1) v entered Isfahan through travelers, mainly coming from Saudi Arabia. The Majority of the confirmed cases consisted of young adults as reported from other countries. They mainly manifested clinical symptoms were similar to those reported in other areas. Because of many patients with influenza like symptoms may not visit the physicians, it is possible that the cases have been under diagnosed.

Session Details

Date: 10/04/2010
Time: 00:00-00:00
Session name: Abstracts 20th European Congress of Clinical Microbiology and Infectious Diseases
Location: Vienna, Austria, 10 - 13 April 2010
Presentation type:
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