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Evaluation of Crimean-Congo haemorrhagic fever patients: epidemiological, clinical and laboratory features

Abstract number: R2340

Caylan R., Keske S., Yapar D., Arslan T., Tasyaran M.A.

Introduction: Crimean Congo haemorrhagic fever (CCHF) is a disease caused by CCHF virus of family Bunyaviridae and transmitted to humans generally by Hyalomma tick bites or by direct contact with blood or other excretes of infected humans. There has been annual increases in case numbers in Turkey since 2002.

Materials and Methods: From April 2007 to September 2009 CCHF virus ELISA and/or RT-PCR confirmed cases in Ankara Ataturk Education and Research Hospital were included in the study. All the informations of the patients have been provided from patient charts.

Results: From 2007 to 2009, 94 comfirmed cases were hospitalized in our hospital. Female to male ratio was 1.14. Median age was 49 (15–76 years) years. 93% of the cases were from rural areas. 74% of patients had tick bite or contact history. Of these 94 patients one (1.06%) was nosocomial infection. The most seen clinical complaints were malaise (90%), fever (85%) and myalgia (81%). Cholecystitis were seen in 6 patients (6.4%). The mean hospitalization duration was 10 (1–62 days) days. Mortality rate was 6.4% (6/94). Ribavirin treatment were administered at 26 patients and also supportive treatment to all patients.

Discussion: CCHF is a big seasonal health problem for Turkey with increasing cases annually. The main risk factor for transmission of disease is mostly tick bite. The cholecystitis seems to be a new defined clinical finding in CCHF. There is not a specific treatment for CCHF; efficacy of ribavirin treatment is controversial. The mortality rate was similiar with those reported in literature from Turkey.

Session Details

Date: 10/04/2010
Time: 00:00-00:00
Session name: Abstracts 20th European Congress of Clinical Microbiology and Infectious Diseases
Subject:
Location: Vienna, Austria, 10 - 13 April 2010
Presentation type:
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