Antibiotic susceptibility monitoring using a Microsoft Access database

Abstract number: R2154

Objectives: The clinical effectiveness of antimicrobial therapy is constantly being undermined by the development of antimicrobial resistance. Appropriate antibiotic prescribing is critical to good patient outcomes and a significant factor in the battle against emerging resistance. As resistance is a constantly evolving problem active, real time surveillance of susceptibility rates is necessary to optimise empirical treatment and prophylactic regimens. We aimed to develop a local surveillance system for monitoring our susceptibility rates and present here the tool and some initial findings.

Methods: All microbiology sample results are retrieved from the laboratory computer system (Telepath, iSoft Laboratory Systems) using the list generation function for either hospital or community (general practice) locations. Microsoft Access databases are used to process these results and allow simple searching for antibiotic susceptibility rates and trends over time. De-duplication of results is achieved by identifying samples from the same hospital number with the same antibiogram to leave single episodes within the selected time frame (either monthly or quarterly). Twenty-three antibiotics and two antifungal agents are imported into the hospital database and cumulative results can be reported across the whole trust, by location (down to ward or speciality level). Eighteen antibiotics are imported into the community database, and cumulative results can be reported across the whole city or by Primary Care Trust. The databases are reported via a separate Access interface, allowing users to select locations and organisms and generate bespoke reports.

Results: Graphical results are obtained to display both the numbers of isolates tested within a time frame, the absolute susceptibility rate and the trend over the time period. An example of the output is shown in the Figure, which displays the susceptibility rate of Staphylococcus aureus from wound swabs to flucloxacillin.

Conclusions: The reporting of trends in antibiotic susceptibilities using Microsoft Access has shown to be both feasible and useful. A simple source for susceptibility rates has proved useful for the development of empirical prescribing guidelines and to allow proactive changes in local prescribing guidelines for both treatment and prophylaxis in response to observed trends.

Session Details

Date: 10/04/2010
Time: 00:00-00:00
Session name: Abstracts 20th European Congress of Clinical Microbiology and Infectious Diseases
Location: Vienna, Austria, 10 - 13 April 2010
Presentation type:
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