Prevalence study on antibiotic consumption in Latvian general practitioners

Abstract number: P1505

Dumpis U., Tirans E., Akermanis M., Veide S.

Introduction: The largest proportion of antibiotics is used in ambulatory care. Despite general consumption data are calculated, they don't provide information on indications for use and demographics of the patients. This information is essential to analyze resistance selection pressure. Easy and cheap methodology was designed to benchmark ambulatory antibiotic use.

Methods: GPs where asked to record data on each patient that received antibiotics during one week in November, 2008. The questionnaire was handed out on registration for the annual conference. Explanation on the methodology was given during the presentation in conference and written instructions. Questionnaire contained information of an antibiotic, dose and dosing interval, indication for use and general demographic data. Participation was voluntary and did not contain financial incentives.

Results: Two hundred forty eight questionnaires out of 600 (41%) where returned by post to the investigators. During one week one GP made mean 113 consultations and antibiotic was prescribed in mean 7 patients (0–33). Children younger than 10 years received most the prescriptions (24.8%). Patients older than 60 years accounted for 13% of the treated. All together, 1763 antibiotics were prescribed during the study period. Most of the patients received monotherapy, only 22 (1.3%) patients where prescribed two antibiotics. Most commonly prescribed antibiotic was amoxicillin (34% of prescribed), amoxicillin/clavulanate (19%) and clarithromycin (8%). Most commonly treated infections where pharingitis (29.1%), acute bronchitis (24.7%) and rhinosinusitis (9.9%). Pneumonia was mostly treated with amoxicillin/clavulanate(25%) amoxycillin (16%) and clarithromycin (19%). Uncomplicated urinary tract infection was mostly treated with oral furagine (27.5%), ciprofloxacin (22%) and norfloxacin (19%).

Conclusions: Methodology employed was cheap and easy to use and provided information on antibiotic use pattern in general practice. Despite rather low return rate and possible bias, we consider obtained information extremely important. Future interventions to reduce ambulatory antibiotic prescriptions should be focused on treatment of acute pharyngitis and bronchitis in children. Another point of significant concern was the high use of fluoroquinolones for uncomplicated urinary tract infection.

Session Details

Date: 10/04/2010
Time: 00:00-00:00
Session name: Abstracts 20th European Congress of Clinical Microbiology and Infectious Diseases
Location: Vienna, Austria, 10 - 13 April 2010
Presentation type:
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