Back

A comparative study between 2009 H1N1 influenzaA virus and seasonal influenza virus infections at a Bangkok hospital, Thailand

Abstract number: P1102

Thiansukhon E., Paitoonpong L., Suwanpimolkul G., Bhattarakosol P., Suankratay C.

Objective: To compare the epidemiology and clinical features between the patients with laboratory-confirmed 2009 H1N1 influenza A and seasonal influenza virus infections.

Methods: A retrospective study of laboratory-confirmed 2009 H1N1 influenza A and seasonal influenza virus infected patients at King Chulalongkorn Memorial hospital was carried out from June 3 to August 20, 2009. Reverse transcriptase polymerase chain reaction tests were used to confirmed diagnosis.

Results: There were 167 and 57 patients with 2009 H1N1 influenza A and seasonal influenza infections. The 2009 H1N1 influenza A group had less mean age (29.1+19.5 years) than the seasonal influenza virus group (36.5+21.6 years) because there are less patients that are more than 50 years old in 2009 H1N1 influenza A group. Of all 224 patients with influenza infection, the most common symptom was fever (89.7%), followed by cough (83.4%), rhinorhea (61.9%), sore throat (54.3%), myalgia (45.3%), and dyspnea (22.9%). There was no significant difference in most clinical manifestations between the two groups except a higher frequency of diarrhea in the 2009 H1N1 influenza A group than the seasonal influenza virus group (16.3 vs 5.3%, p = 0.042). Pneumonia was noted in 41 (24.7%) patients in the 2009 H1N1 influenza A group, in comparison with 5 (8.8%) patients in the seasonal influenza virus group (p = 0.013). The mortality rate was 1.8% in the 2009 H1N1 influenza A group, but no patient in the seasonal influenza virus group died.

Conclusions: The patients with 2009 H1N1 influenza A infection are younger than seasonal influenza virus infected patients. Diarrhea is only symptom that is more common in 2009 H1N1 influenza A infected patients. 2009 H1N1 influenza A infection seems to be more severe because there are more pneumonia and death.

Clinical data of H1N1 2009 influenza A and seasonal influenza infections in King Chulalongkorn Memorial Hospital

 Total, n (%)H1N1 2009 (n = 167)Seasonal (n = 75)P-value
Fever200 (89.7)147 (88.6)53 (93)0.453
Cough186 (83.4)144 (86.7)42 (73.7)0.037
Myalgia101 (45.3)72 (43.4)29 (50.9)0.357
Rhinorrhea138 (61.9)99 (59.6)39 (68.4)0.271
Sore throat121 (54.3)89 (53.6)32 (56.1)0.76
Dyspnea51 (22.9)42 (25.3)9 (15.8)0.2
Diarrhea30 (13.5)27 (16.3)3 (5.3)0.042
Vomit29 (13)26 (15.7)3 (5.3)0.065
Pneumonia46 (20.6)41 (24.7)5 (8.8)0.013
Dead3 (1.3)3 (1.8)00.572

Session Details

Date: 10/04/2010
Time: 00:00-00:00
Session name: Abstracts 20th European Congress of Clinical Microbiology and Infectious Diseases
Subject:
Location: Vienna, Austria, 10 - 13 April 2010
Presentation type:
Back to top