Aetiology of community-acquired pneumonia in children during the influenzaA (H1N1) outbreak
Abstract number: O215
Michelim L., Fracasso J., Garrido P., Buffon V., Generosi L., Oliveira Filho P.
Objective: In July 2009, a respiratory illness outbreak caused by influenza A virus (H1N12009) was identified in Caxias do Sul, Brazil. The aim of the study is to determine the impact of influenza A H1N1 2009 on the viral etiology of pneumonia among children admitted at General Hospital of Caxias do Sul from July 01 to August 31, 2009.
Methods: Retrospective medical chart reviews on the pediatric hospitalized patients diagnosed with acute respiratory infection between July and August 2009. We evaluated demographic data, clinical and laboratory findings. Nasopharyngeal aspirates for detection of respiratory viruses were analyzed by indirect immunofluorescence (IFI) and real-time polymerase chain reaction (RT-PCR).
Results: A total of 53 children were hospitalized for severe acute respiratory disease, according to the criteria established by the Health Ministry of Brazil. Most patients were male (60.3%) and had less than one year of age (35.8% with less than 6 months and 26.4% between 6 and 12 months). Comorbidities were identified in 9.4%. Fifteen patients were referred for the intensive care unit, and one third of them required mechanical ventilation. No deaths occurred. Six patients (11.3%) had confirmed influenza A (H1N1) and in 27 children (50.9%) were identified respiratory syncytial virus (RSV) as the etiologic agent of pneumonia.
Conclusion: As in previous years, respiratory syncytial virus has remained as predominant agent in the etiology of viral pneumonia in spite of the outbreak of influenza A (H1N1) experienced in 2009.
|Session name:||Abstracts 20th European Congress of Clinical Microbiology and Infectious Diseases|
|Location:||Vienna, Austria, 10 - 13 April 2010|
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