Changes in the detection of C.trachomatis in a female population in Greece during the last 4years
Abstract number: R2280
Kakisi O., Avdeliodi C., Simou M., Kada H., Falagas M.
Background: Our purpose was to measure and compare the annual incidence of Chlamydia trachomatis infection in an urban population of women of reproductive age during the last 4 years in Athens Greece and report the relevant findings.
Material and Methods: In total, 6554 endocervical samples of unique women that attended our hospital outpatients' gynaecological department during the last 4 years (1/1/200531/12/2008) were included in the study. The molecular method used for the detection of C. trachomatis was SDA (strand displacement amplification) BD PROBE TEC TM. Patients were also stratified by age, pregnancy, previous miscarriages, symptoms and nationality.
Results: The figure shows the respective incidences of C. trachomatis in our study population during 20052008. The observed decrease is in the magnitude of >50% between 2005 and 2008 (P < 0.05). To our knowledge there exists no known factor for the significant decrease in the measured incidence of C. trachomatis infection of women in Athens, Greece.
Conclusion: In light of the recent discovery of new plasmid mutants of C. trachomatis that evade detection by standard molecular methods in Sweden, we believe that attention is warranted for the observed decrease in our own study population. Although the BD PROBE TEC assay is believed not to be affected by the presence of mutant strains, there is an evident need for the investigation of factors that have attributed to this change.
|Session name:||19th European Congress of Clinical Microbiology and Infectious Diseases|
|Location:||Helsinki, Finland, 16 - 19 May 2009|
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