Prevelance of blood-borne viruses amongst antenatal clinic patients and blood donors in a tertiary referral hospital in Oman
Abstract number: P2004
Schuster H., Serebour E., Nograles J., Al-Belushi I., Hassan K.
Objective: Recent data published for the Gulf region on chronic hepatitis B infection in pregnancy suggested a prevalence of 7.1% for Omani woman. The sample population in this report was small and we intended to re-evaluate the prevalence of Hepatitis B infection for pregnant woman attending antenatal care at Sultan Qaboos University Hospital. We compared the data for Hepatitis B and HIV infection and also assessed the Hepatitis C infection rate amongst of a blood donor population at the same institution.
Methods: The laboratory information for HIV, HBV and HCV infection data was obtained from the laboratory information system for the period from 01/07/2006 to 31/12/2008. The data was analysed with MSExcel and Minitab.
Results: Amongst 3142 pregnant woman a prevalence rate of 7.07% was found for chronic HBV infection. 0.12% of chronic infections in pregnancy were of high infectivity. For 0.34% neither Hepatitis B e antigen nor anti-Hepatitis B e antigen antibody could be detected. There was a significant difference between the HBV infection rate amongst blood donors (n = 6726) and pregnant women 2.81% vs. 7.07 respectively. The HIV rate was found to be 0.17% for pregnant women and amongst blood donors 0.01%. Only blood donors were tested for HCV infection and a rate of 0.45% was seen.
Amongst blood donors anti-Hepatitis core antibody was detected in 18.8% of 745 donors without Hepatitis B surface antigenaemia. Hepatitis core antibody testing had only been introduced into blood bank screening in November 2008.
Conclusions: The rate of hepatitis B infection in Omani pregnant women remains at an intermediate endemicity level. The lower blood donor prevalence may be explained by a pool of stable donors although ad hoc blood donations by relatives are common. The HIV rate amongst pregnant women is very low and even lower in the blood donor population. The HCV infection rate amongst blood donors is very low in the Sultanate.
A high rate of anti-Hepatitis B core antibody presence was found for blood donors without Hepatitis B surface antigenaemia. Because of the danger of occult HBV infection in such cases strategies for effective testing have to be found in order to maintain sufficient quantities of blood products.
Prevalence of blood borne viruses amongst antenatal clinic patients and blood donors in a tertiary referral hospital in Oman from 01/07/2006 to 31/12/2008
|Session name:||19th European Congress of Clinical Microbiology and Infectious Diseases|
|Location:||Helsinki, Finland, 16 - 19 May 2009|
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