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Osteoarthricular involvement in brucellosis: study of 155 cases

Abstract number: P1528

Turan H., Serefhanoglu K., Karadeli E., Togan T., Arslan H.

Objectives: Despite the high morbidity rates of brucellosis in Turkey, its mortality rate is relatively low. Osteoarthiculary complications has been reported in 10–80% of all brucellosis cases. The aim of this study was to determine the rates, types and clinical features osteoarthricular involvement of 155 brucellosis cases.

Methods: 155 brucellosis cases admitted to our hospital between June 2003 and November 2008 were evaluated in terms of clinical and laboratory findings. The diagnosis was established on the basis of standard tube agglutination titre of 1/160 of antibodies for brucellosis and/or positive blood sample cultures. Osteoarthicular involvement was defined by inflammatory signs in peripheral joints with radiologic alterations and/or lumbar and sacral vertebrate magnetic resonance imagine in for patients who had lumbago of brucellosis.

Results: Sixty-five patients (42%) had osteoarthicular involvement (55.4%male, 44.6% female). The mean age was 45.8 18 years. Sacroiliitis was the most common involvement (n: 39, 60%), followed by spondylodiskitis (n: 27, 41.5%), peripheral arthritis (n: 10, 15.4%), bursitis (n: 1, 1.5%). In addition, there were 11 (17.5%) patients with more than one site of involvement: nine had concomitant sacroiliitis and spondylodiskitis, one had sacroiliitis and peripheral arthritis, and the remainder sacroiliitis and bursitis. Spinal epidural abscess was found seven cases. Sacroiliitis has been determined symmetrical 82% rate. Lumbar spondylodiskitis was the most common involvement among the spondylodiskitis (n:25, 92.5%). All of the cases were treated doxycycline and rifampicin or streptomycin, rifampicin and doxycycline according to their clinical progress at least 3 months.

Conclusion: Brucellosis should be included in the differential diagnosis of any patient with arthralgia or symptoms of sacroiliitis and spondylodiskitis especially where this infection is endemic countries such as Turkey.

Session Details

Date: 16/05/2009
Time: 00:00-00:00
Session name: 19th European Congress of Clinical Microbiology and Infectious Diseases
Subject:
Location: Helsinki, Finland, 16 - 19 May 2009
Presentation type:
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