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Prevalence of quinolone susceptible Pseudomonas aeruginosa and Staphylococcus aureus in delayed-healing diabetic foot ulcers in Ekpoma, Nigeria

Abstract number: P1395

Agwu E., Ihongbe J., Inyang N.

Aim: To investigate the prevalence and antibiogram of Pseudomonas aeruginosa and Staphylococcus aureus from delayed-healing foot ulcers of diabetic patients in Ekpoma.

Methods: Using standard aseptic microbiological methods, 220 delayed-healing diabetic-foot ulcer samples were analyzed for bacteria isolation, identification and susceptibility test. Chi-square (á=0.01) was used to test the statistical significance of data obtained.

Results: Out of 220 samples analyzed, 82.3% were infected (41.8%P. aeruginosa, 30.0%S. aureus and 10.5% co-infection of P. aeruginosa and S. aureus). There was statistically significant (p < 0.01) association between P. aeruginosa and S. aureus in the population studied. Among the quinolones tested, S. aureus and P. aeruginosa showed the highest (74.2% and 71.3%) and lowest (38.2% and 34.8%) susceptibilities to Levofloxacin and Sparfloxacin respectively. P. aeruginosa was also: 68.7% susceptible to rifampicin; 53.0% to erythromycin, 52.2% to vancomycin; 38.3% to ceftriazone; 36.5% to cefuroxin; and 32.2% to oxacillin. S. aureus was: 51.7% susceptible to rifampicin, 37.1% to cefuroxin; 33.7% to ceftriazone; 28.1% to vancomycin and 25.8% to oxacillin.

Conclusion: Delayed-healing diabetic foot ulcers in Ekpoma are colonised by levofloxacin and sparfloxacin susceptible Pseudomonas aeruginosa and Staphylococcus aureus. Surveillance with improved diagnostic facilities, surgical and biosurgical debridement of nonviable tissue, to halt progression of infection is recommended.

Session Details

Date: 16/05/2009
Time: 00:00-00:00
Session name: 19th European Congress of Clinical Microbiology and Infectious Diseases
Subject:
Location: Helsinki, Finland, 16 - 19 May 2009
Presentation type:
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