Incidence of infections in burn centres in France
Abstract number: P630
Vinsonneau C., Ravat F., Le Floch R., Ainaud P., Bertin-Maghit M., Carsin H., Perro G.
Objectives: Infections in burn patients are the leading cause of delayed death. To improve the prognosis of burns, prevention of infectious disease is mandatory, but large epidemiological study are lacking in our French population. This study aims to assess the incidence and characteristics of infections in this population.
Methods: Non-interventional study, epidemiological, longitudinal, conducted among 15 burn centres in France and held a period of three months from July to September 2006. Only new episodes of infection occurring during this period have been taken into account. Among the 784 patients admitted during the study period in participating centres, 348 had a burn centre stay strictly included within the range of the observation time.
Results: The characteristics of the whole population are (median, IQR): age 35 y.o , sex ratio (M/F) 7/10, Total Burn Surface Area (TBSA) 10% . 24% are younger than 15 y.o and 15% have a TBSA > 30%. The overall incidence of infected patients is 19% (N = 784) and 48.3% for burns over 30% (N = 120). The overall incidence of infections is 32.7%. The density of incidence of infected patients is 1.7 episodes/100 patient-days and density incidence of infections is 2.0 episodes/100 patient-days. The site of infection and their relative rate are burn wound (32%), lung (32%), urine (17%) and bacteraemia (14.6%). Multi-site infections represent 14.6% of all cases. Gram-negative pathogens are the leading strains (72%) with Pseudomonas aeruginosa (28%), Proteus (18%), E. coli (16%), Serratia (11%), Klebsiella (4%). Gram positive pathogens represent 55% of all infections with Staphylococcus aureus (32%) and Enterococci (9%). Yeasts represent about 5%. Strains antibiotic susceptibility analysis shows that 27% of them are multi-resistant. Overall mortality is 5%.
Conclusion: Infections acquired in burn centres are frequent and most of the patients experience several episodes. Burn wound and lungs mostly affected and micro-organisms have not infrequently a multi-resistant phenotype.
|Session name:||19th European Congress of Clinical Microbiology and Infectious Diseases|
|Location:||Helsinki, Finland, 16 - 19 May 2009|
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