NA Antimicrobial prophylaxis in surgery: an international survey

Abstract number: O394

Alexiou V., Ierodiakonou V., Peppas G., Falagas M.

Background: We sought to investigate current clinical practice of antimicrobial prophylaxis (AMP) in surgery.

Methods: Survey regarding the administration of AMP to patients, without comorbidity or allergy, undergoing surgery, among surgeons indexed as corresponding authors for articles published in general surgery, orthopedics, gynaecology and cardiac surgery journals.

Results: 1068 surgeons answered (response rate 68%). 26.1% of the respondents do not begin infusion of the first antimicrobial dose within 1 hour from incision, as suggested by guidelines, 27.2% continue administering AMP for 2 or more days after surgery, including 7.6% that continues for 4–7 days after surgery. There were significant differences in the selection of AMP regimens between participating surgeons from Europe and North America. Furthermore, 19% of Europeans order infusion of the first antimicrobial dose during incision compared to 3.9% of North Americans, 74.2% of Europeans discontinue AMP within 24 hours from surgery compared to 86% of North Americans. Finally, 31% of general surgeons originating from the North America administer supplementary oral prophylaxis for colectomy compared to only 5% of surgeons from Europe.

Conclusions: Even among experts, certain aspects of AMP are rather controversial. A uniform, evidenced-based practice is warranted especially in the era of increasing antimicrobial resistance.

Session Details

Date: 16/05/2009
Time: 00:00-00:00
Session name: 19th European Congress of Clinical Microbiology and Infectious Diseases
Location: Helsinki, Finland, 16 - 19 May 2009
Presentation type:
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