Bronchial asthma and Chlamydia pneumoniae
Abstract number: R2543
Kalikatzaros D., Stagas M., Hristodoulou G., Mavrea S., Anastasakou E.
Introduction:C. pneumoniae is a known cause for respiratory diseases such as pneumonia, bronchitis and more but it has not yet been determined the role at the pathogenesis of bronchial asthma. The purpose of our study was to detect the presence of C. pneumoniae antibodies to the serum of patients of our hospital and correlate with the disease.
Material and Methods: We studied 750 patients from which 470 were female and 280 male. All patients were nursed at the pneumonological clinics of our hospital during the last year (20062007). 100 healthy controls were also used. 165 out of the 750 patients had symptoms of bronchial asthma following a respiratory infection. At those 165 patients as well as at the 100 controls (IFA) was used to detect C. Pneumoniae antibodies while the rest immunological tests were negative.
Results: All 165 patients had positive IgG antibodies for C. pneumoniae in titles ranging from 1/16 to 1/512 with a higher percentage at titles 1/32 and 1/64. The healthy controls had a high title antibodies at 1/16 while no one had a title of 1/128 or 1/512.
Conclusions: As shown on the table the title of IgG antibodies for C. pneumoniae is much higher to patients with bronchial asthma than it is to the healthy individuals. Despite the fact that high titles of IgG antibodies for C. pneumoniae can be found at countries with low morbidity for bronchial asthma (tropical countries) it is possible that chronic infection with C. pneumoniae can be a causing factor for the disease.
|Session name:||18th European Congress of Clinical Microbiology and Infectious Diseases|
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