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ESBL-producing Enterobacteriaceae among neonates in an academic clinical centre, Gdansk, Poland

Abstract number: R2538

Rybak B., Naumiuk L., Naumiuk E., Samet A., Domzalska-Popadiuk I.

Objectives: The aim of this study was to analyse occurrence of ESBL [Extended-Spectrum Beta-Lactamases] producing Enterobacteriaceae in patients who were hospitalised in the Depart. of Neonatology Medical University of Gdansk.

Methods: We analysed microbiological records obtained from 2003 to 2007. Strains were identified by classical method and VITEK, VITEK 2 (BioMerieux). Production of ESBL was detected by double disk method.

Results: In the studied period 8632 patients were hospitalised. ESBL+ isolates were recovered from 425 patients. In 2003 ESBL+ isolates were recovered from 216 patients, then 2004 – 48 patients, 2005 – 27 patients, 2006 – 110 patients and 2007 – 24 patients.

The most often isolated was Enterobacter aerogenes from 131 patients (47.1%), then Klebsiella pneumoniae 96 patients (34.5%) Escherichia coli 17 patients (6.1%); Enterobacter cloacae 16 patients (5.8%); Klebsiella oxytoca 11 patients (4%); Citrobacter freundii 6 patients (2.2%) and Enterobacter intermedius 1 patient.

Isolates were recovered from stools and rectal swabs (54%), respiratory tract (37.4%), urine (3.89%) and blood (1.73%).

All strains were susceptible to carbapenems, about 90% to fluoroquinolones and nearly 80% urine isolates to nitrofurantoin, but about 90% isolates were resistant to aminoglicosides and co-trimoxazole.

Conclusions: High percentage of ESBL carriage among children complicates infection control measures and treatment of common infections like urinary tract infection.

Newborns should be screened for ESBL carriage in our setting.

Session Details

Date: 19/04/2008
Time: 00:00-00:00
Session name: 18th European Congress of Clinical Microbiology and Infectious Diseases
Subject:
Location: Barcelona, Spain
Presentation type:
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