Seroepidemilogical study of HTLV and its clinical impacts in thalassaemia, haemophilia and haemodialysis patients in Hormozgan

Abstract number: R2380

Abedi F., Shkibzade A., Khalvati B., Yavarian M.

Background: Transmission of blood borne infections is common among multitransfusion patients such as thalassaemia, Hemophilia and haemodialysis patients. HTLV (Human T-Lymphotropic Virus) is one of the Retroviruses which is transmitted by blood and its products. In Iran HTLV is endemic only in Khorasan. This virus causes (HAM/TSP) and (ATL). In this study we consider the seroepidemiological patterns of HTLV infections in thalassaemia, Hemophilia and haemodialysis patients in Hormozgan in South of Iran in order to assess the possibility of the virus trasmision and its clinical impacts.

Methods: In this study, 210 patients, including 163 thalassaemias, 40 haemodialysis patients and 7 hemophilia (98 female, 112 male) with the age range of 9 to 79 were analysed. Their plasma was tested for detection of Ab against HTLV and patients were examined for its clinical manifestations.

Results: Anti-bodies against HTLV were detected in 2.38% (5 patients) which is higher than its prevalence in healthy individuals. All of positive samples were belonging to Thalassaemia patients. Anti-body positive patients were symptomatic clinically as well.

Conclusion: This study shows that multitransfusion patients were infected probably via blood transfusion or haemodilyse and existence of this virus is not limited only to the Khorasan.

Session Details

Date: 19/04/2008
Time: 00:00-00:00
Session name: 18th European Congress of Clinical Microbiology and Infectious Diseases
Location: Barcelona, Spain
Presentation type:
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