Staphylococcus aureus nasal carriage among diabetic and non-diabetic volunteers

Abstract number: R2339

Sergouniotis P., Sergouniotis F., Karakoida C., Koukou E., Papoulia E.

Introduction:S.aureus is one of the most important human pathogens. It is a common cause of hospital and community-acquired infections worldwide, the incidence of which has been rising with increasing emergence of drug resistant strains.

Purpose: This study aims to estimate the extent of S.aureus carriage, particularly MRSA, among diabetic and non-diabetic residents of Fokida, a rural area in central Greece, by performing nasal swabs.

Methods: We conducted a cross-sectional study involving 82 adults. Samples were collected from the anterior nares using sterile cotton wool swabs. Nasal specimens were examined for the presence of S.aureus by standard quantitive culture methods including the tube coagulase test, the Microscan system and the Kirby-Bauer disk-diffusion test. Epidemiological information concerning risk factors for nasal carriage was also obtained. These included history of antibiotic usage in the past month, previous hospitalisation, history of chronic illnesses and residence in nursing home.

Results: A total of 82 individuals were examined. These comprised 40 diabetic (48.8%) and 42 non-diabetic (51.2%) persons with ages ranging from 14 to 85 years (mean age 56.68±17.04 years). None of the participants were ever hospitalised or had any other risk factor. Overall nasal carriage of S.aureus in this study population was 31.7% (26/82). From 82 nasal swabs collected, 4 MRSA isolates (4.88%) were identified, 2 of which were from diabetic persons. S.aureus positivity was noted in 12 of the 40 diabetic patients (30%) and 14 of the 42 healthy adults (33.33%). Heavy colonised carriers were 12 persons (46.1%) and half of them were diabetics.

Conclusions: Our study showed that there was no association between S.aureus carrier state and diabetes mellitus. Among the diabetic subjects, S.aureus colonisation was not associated with level of HBA1c and glucose control.

The findings also revealed that nasal carrier rates among residents of Fokida (31.7%) are higher as compared to those among the area's hospital personnel (20%), according to a previous study of ours. The prevalence of MRSA in our study population was found to be 4.88%.

Session Details

Date: 19/04/2008
Time: 00:00-00:00
Session name: 18th European Congress of Clinical Microbiology and Infectious Diseases
Location: Barcelona, Spain
Presentation type:
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