Update on Scedosporium/Pseudallescheria infections

Abstract number: P2193

Horré R., Lackner M., de Hoog S., Bouchara J.P.

Objective:Pseudallescheria boydii and Scedosporium prolificans are truly emerging fungal pathogens. They cause local and/or disseminated infections in human and animals. In 2002, a "Working Group on Pseudallescheria/Scedosporium Infections" was established by the European Confederation Of Medical Mycology (ECMM) and accepted as worldwide working group by the International Society For Human And Animal Mycology (ISHAM) in 2006. The aim of this working group is to collect strains and data, to improve our knowledge in the pathogenic mechanisms of these fungi, and to develop new diagnostic methods and treatment options. A summary of the latest results of the members of this working group will be presented.

Methods: Studies have been performed about different human and fungal perspectives, such as: (1) clinical significance studies, (2) taxonomical research, (3) selective detection using different techniques (e.g. serology, PCR, culture, histopathology), (4) resistance studies, (5) treatment investigations, (6) virulence factors, (7) epidemiology, and (8) ecology.

Results: For better understanding of these fungi as human and animal pathogens results have been obtained with

•a recently developed selective culture media, which was used for the isolation from environmental, as well as, from clinical specimen

•taxonomic evaluation and reclassification

•resistance studies

•occurrence in artifical and native environment

•analyses of published case reports

Conclusion: Since the first meeting of the ECMM (-ISHAM) Working Group on Pseudallescheria/Scedosporium Infections (April 2004), lots of interesting results have been achieved and established by our worldwide network of members.

We welcome interested physicians to support our work by sending strains, participating in studies, or sending data. Further information is available on our website:

Session Details

Date: 19/04/2008
Time: 00:00-00:00
Session name: 18th European Congress of Clinical Microbiology and Infectious Diseases
Location: Barcelona, Spain
Presentation type:
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