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Susceptibility patterns of Ureaplasma urealyticum isolates, obtained form urogenital samples

Abstract number: P2072

Agudo S., Domingo D., Somodevilla A., Alarcon T., López-Brea M.

Introduction:Ureaplasma urealyticum can be isolated from the human urogenital tract as common comensal or pathogen. It can cause various pathologies such as non-gonococcal urethritis, bacterial vaginosis, cervicitis, endometritis or pelvic inflammatory disease. The aim of this study was to analyse antimicrobial susceptibility of Ureaplasma urealyticum isolated from urogenital samples.

Methods: All the urogenital samples received at the Department of Microbiology (Hospital Universitario de la Princesa, Madrid) from January 2005 to November 2007 were collected into the selective broth and transported to the laboratory. The diagnostic method was using Mycoplasma IST 2 kit (BioMerieux), a biochemical comercial method. Susceptibility to doxycycline, josamycin, azithromycin, erythromycin, clarithromycin, tetracycline, ofloxacin and ciprofloxacin were tested using Mycoplasma IST 2 kit.

Results: Six hundred and fifty nine urogenital samples were positive to Ureaplasma urealyticum in this period. 42.0% were obtained from women samples (165 endocervical exudates and 112 urine samples) and 58.0% were obtained from men samples (183 protatitis protocols, 92 uretral exudate and 107 urethritis protocols). The susceptibility rate was 89.0% for doxycycline, 85.7% for tetracycline, 11.9% for ofloxacin, 2.1% for ciprofloxacin, 38.7% for erythromycin, 38.4% for azitromycin, 72.9% for clarithromycin and 73.7% for josamycin. In the previous years, from January 2001 to December 2004, the susceptibility rate to ofloxacin and erythromycin were 70.7% and 62.5% respectivily.

Conclusion: According our review, the resistance to quinolones was higher than resistance to other antibiotics tested. Ofloxacin resistant strains have increased from 29.3% in the years 2001–2004 to 88.1% in the years 2005–2007. The resistance rate to erithromycin also was higher in the years 2005–2007 than in the previous years.

Session Details

Date: 19/04/2008
Time: 00:00-00:00
Session name: 18th European Congress of Clinical Microbiology and Infectious Diseases
Subject:
Location: Barcelona, Spain
Presentation type:
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