Toxoplasma gondii infection in centre of Portugal: seroprevalence during 20002006
Abstract number: P1878
Sousa M.C., Silveira L., Poiares-da-Silva J., Donato A.
Toxoplasma gondii is an obligate intracellular protozoan that can infect all kind of birds and all mammals including humans and is common throughout the world. The prevalence varies according to social and cultural habits, pet cats in homes and geographic factors. Domestic cats are considered to be an important source of T. gondii infection. Toxoplasmosis is the most widespread zoonosis and an important human disease particularly the congenital infection where it could cause visual and neurological impairment and mental retardation in children. In the present study, the prevalence of T. gondii infection in centre of Portugal were determined from January 2000 to December 2006 by testing the sera collected from women (n = 1,003) and men (n = 168) for T. gondii immunoglobulins G and M antibodies. The anti-toxoplasma IgM and IgG were determined using ELFA technique (Enzyme Linked Fluorescence Assay) (VIDAS Toxo, BioMériuex). Results for IgG antibodies were reported in International Units (IU); samples with 4 IU were considered positive for T. gondii immunoglobulin G antibodies. The results for IgM were reported as positive if the index was >0.65 and negative if was <0.55. In women, the rates of T. gondii IgM antibodies were 0.9% (9/1,003) and 24.9% (250/1,003) for IgG antibodies. Along the study period 20002006 the toxo anti-IgG ranged from a minimum of 13.6% in 2005 to a maximum of 30.3% in 2001. In men, the rates of IgM antibodies were 0% and 58.9% (99/168) for IgG antibodies. The total rate of positively of T. gondii antibodies was 30% (351/1,171) and the negativity was 70% (820/1,171). The age-adjusted T. gondii seroprevalence among males with 2029 years old (n= 24) was 20.8% and among females with 2029 years old was 27.3% (135/495). The prevalence of T. gondii IgG antibodies increased with age: the highest positive rates (83%) have been founded in persons with age more than seventy years old (25/30). These results indicate that preventive measures should be implemented in pregnant women's to prevent the congenital toxoplasmosis.
This work was supported FCT POCTI (FEDER).
|Session name:||18th European Congress of Clinical Microbiology and Infectious Diseases|
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