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Copper and zinc plasma level in brucellosis patients in Iran

Abstract number: P1861

Hajabdolbaghi M., Jafari S., Alipouran A., Mobayen M.

Objectives: Brucellosis which is a zoonotic disease is a common endemic disease and health problem in Iran. Based on multiple studies, copper and zinc have influence on immune system. In other studies it has been shown that plasma levels of these trace elements in patient with Brucellosis are changing. The aim of this study was to measure the serum zinc and copper level in patients with brucellosis and in comparison with healthy individuals.

Methods: In this cross sectional study the plasma level of zinc and copper of brucellosis patients were measured and compared to the level of healthy individuals.

Results: Forty three patients (34 men and 9 women) with brucellosis matched with 43 healthy (34 men and 9 women) individuals were included in two teaching hospital in two cities of Iran in 2006. The mean age of patients were 40.14 years old (range 14–60 years old) and the mean age of healthy individuals were 40.3±15.89 years old (range 14–60 years old). The plasma level of copper was found to be significantly higher in patients with brucellosis than healthy individuals (160.84±54.61 vs 101.74±27.37 mg/dl). The plasma level of zinc was less than healthy individuals (91.47± 46.91 vs 107.19±35.18 mg/dl) but was not statistically significant. Zinc plasma concentration was lower in female brucellosis patients compared with healthy female individuals (80.33± 44.2 vs 119±28.17 mg/dl).

Conclusion: Plasma zinc and copper level showed significant alterations in patients with brucellosis compared with healthy persons and there is influenced of gender on it. It is still not clear that these changes are result of the disease or these changes predispose individuals to infection.

Session Details

Date: 19/04/2008
Time: 00:00-00:00
Session name: 18th European Congress of Clinical Microbiology and Infectious Diseases
Subject:
Location: Barcelona, Spain
Presentation type:
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