Focal organ involvement in a series of 99 brucellosis patients

Abstract number: P1858

Turunc T., Demiroglu Y., Aliskan H., Colakoglu S., Arslan H.

Objectives: Brucellosis is a zoonosis which affects all organs and systems and causes severe complications. The aim of this study was to evaluate demographic features, clinical findings and treatment outcomes of brucellosis with focal involvement.

Methods: This is a prospective study and included 99 patients with brucellosis aged over 15 years and presenting to our clinic between January 2003 and July 2007.

Results: The study included 99 patients, of whom 50 (50.5%) were female and 49 (49.5%) were male. They were aged between 15 and 77 years with a mean of 50.1 years. Out of 99 patients, 69 (69.6%) had acute brucellosis, 24 (24.2%) subacute brucellosis and 6 (6.2%) chronic brucellosis. Eighty-two patients (82.8%) had a history of consumption of unpasteurised milk and dairy products and 29 patients (29.2%) had a history of stockbreeding. In addition, 16 patients (16.1%) had a history of brucellosis at least one year before. The most frequent complication was musculoskeletal involvement (n = 80), followed by endocarditis (n = 9) and peritonitis (n = 1). The most frequent musculoskeletal involvement was spondylodiscitis (n = 50;50.5%), followed by sacroileitis (n = 21;21.2%) and peripheric arthritis (n = 9;9.09%). Brucella melitensis was isolated in blood cultures of 42 patients, spinal fluid cultures of one patient, ascites fluid culture of one patient, joint fluid culture of one patient and psoas abscess culture of one patient.

Conclusion: Brucellosis is a disease presenting with various clinical pictures and severe complications and difficult to diagnose. Therefore, caution should be exerted with focal organ involvement and brucellosis cases should be followed at regular intervals in regions where the disease is endemic. In addition, it should be kept in mind that Brucella spp. can be isolated in all sterile bodily fluids and that specimens should be obtained from appropriate sites.

Session Details

Date: 19/04/2008
Time: 00:00-00:00
Session name: 18th European Congress of Clinical Microbiology and Infectious Diseases
Location: Barcelona, Spain
Presentation type:
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