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Clinical manifestations and outcomes of therapy in 44 cases of brucellar spondylitis

Abstract number: P1856

Hasanjani Roushan M.R., Laly A., Soleimani Amiri M.J., Janmohammadi N.

Objectives: For assessing the clinical features and outcome of treatment in brucellar spondylitis

Methods: This study was conducted on 44 cases with brucellar spondylitis from April 1998 through September 2007.The clinical manifestations and outcome of treatment were recorded

Results: Twenty six (59.1%) cases were male. the mean age of the patients was 47.9±16 years. Back pain, sweating, fever and artheralgia were the most clinical findings. The disease was acute in 23 (52.3%), sub-acute in 18 (40.9%) and chronic in 3 (6.8%) of the cases. Brucellar spondylitis was seen in 38 (86.4%) cases in lumbar and lumbo-sacral in 3 (6.8%) cases in cervical regions. Twenty cases were treated with doxycycline plus rifampin for 4 months. Relapse was seen in 1 (5%) case. Relapse was seen in 1 (9.1%) of 11 cases who were treated with cotrimoxazole plus rifampin for 4 months. Relapse was not seen in 15 cases treated with streptomycin for 14 days plus doxycycline and rifampin for 4 months

Conclusion: Brucellar spondylitis may develop in any sites of the spine mostly in the lumbar region. Streptomycin for 14 days plus doxycycline plus rifampin for four months may be better regimen for therapy of brucellar spondylitis.

Session Details

Date: 19/04/2008
Time: 00:00-00:00
Session name: 18th European Congress of Clinical Microbiology and Infectious Diseases
Subject:
Location: Barcelona, Spain
Presentation type:
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