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Clinical features of spondylodiscitis: a four-year survey

Abstract number: P1851

Turkulov V., Vukadinov J., Kne[zcaron]evic A., Sevic S., Doder R., Canak G.

Objectives: The spinal column diseases take a prominent place in the morbidity of adults. Spondylodiscitis represents an inflammatory process, localised in the bodies of spinal vertebrae and intervertebral disk. This research aimed to determine the most common complaints and clinical features of patients with spondylodiscitis as well as to analyse the correlation between the disease outcome and the beginning of therapy.

Methods: retrospective analysis of medical documentation was used, which encompassed 40 patients treated for spondylodiscitis at the Clinic for infectious diseases, Clinical Centre of Vojvodina, during the last four years. The diagnosis was confirmed in all patients using magnetic resonance (MR) imaging of spinal column.

Results: The average age of the patients was 58.5 years. In most of them, the inflammatory process was located in lumbar region (67.5%), then in lumbar sacral segment of spinal column (17.5%), while in the minority of the patients it was located in thoracic (7.5%) and cervical segment. The time before onset of the disease and establishing the diagnosis and beginning the therapy varied from one month (45%) to six and more months (17.5%). In all the patients the laboratory findings showed signs of inflammatory process. The aetiological agent has not been proved in 80% of them, in 12.5% it was tuberculosis of spinal column and in 7.5% brucellosis was found out. All patients were subjected to conservative-parenteral antibiotic therapy (tuberculostatic in case of tuberculosis). A combination of two or three antibiotics during six weeks to six months (51.6 days in average) was applied. Most often used antibiotics were the third generation cephalosporins, vancomycin, metronidazole, fluorochinolones, and aminoglycosides. In 4 (10%) patients surgical treatment was necessary in addition to the conservative one. The results of the therapy were followed out by clinical examination, as well as by laboratory findings and MR imaging.

Conclusion: The outcome of the disease was favourable in most of the patients – recovery or recuperation with lesser or major sequels. The sooner the diagnosis was established, the more favourable outcome was. It is important to consider this disease because timely diagnostics and therapy shorten the duration of the illness, reduce the costs of treatment and minimize the possibility of sequels.

Session Details

Date: 19/04/2008
Time: 00:00-00:00
Session name: 18th European Congress of Clinical Microbiology and Infectious Diseases
Subject:
Location: Barcelona, Spain
Presentation type:
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