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Is there any difference between non-smoker and smoker tuberculous patients in clinical manifestations and radiographic findings?

Abstract number: P1561

Sharifi-Mood B., Metanat M.

Introduction and Aim: Cigarette smoking and tuberculosis are responsible for a large portion of morbidity and mortality in the developing countries. It has been well documented that smoking increases the risk of tuberculosis (TB). However, a few studies have evaluated the impact of smoking on TB. In order to evaluate the influences of smoking on the clinical manifestations and radiographic findings in smoker tuberculous patients, we conducted this study.

Materials and Methods: From May 2005 to December 2006, two hundred smear positive pulmonary TB patients who referred to Zahedan tuberculosis centre for treatment, identified. Then, we evaluated the influences of smoking on the Clinical and radiograohic manifestations of TB.

Results: A total of 200 TB patients, including 100 (50%) who had ever smoked, were studied. There was no significant difference in age between smokers and non-smokers. Smokers more likely to have pulmonary underlying diseases such as chronic bronchitis and asthma and a duration of symptoms > three months, and less likely to have extra-pulmonary involvement. Radiographically, more smokers with pulmonary tuberculosis (PTB) presented with cavitation, miliary lesions, multiple nodules or masses, and infiltrations in two lungs than non-smokers. Also, there was a significant delay in sputum smear conversion time in smoker patients with pulmonary tuberculosis at 2, 4 and 6 months of treatment (P < 0.05).

Conclusion: Our results showed that smoking is significantly associated with clinical and radiographic manifestations of PTB and a delay in sputum smear conversion time.

Session Details

Date: 19/04/2008
Time: 00:00-00:00
Session name: 18th European Congress of Clinical Microbiology and Infectious Diseases
Subject:
Location: Barcelona, Spain
Presentation type:
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