Closed tracheal suction systems for prevention of ventilator-associated pneumonia

Abstract number: P816

Siempos I., Vardakas K., Falagas M.

Objective: By meta-analysis of randomised controlled trials (RCTs), we assessed the evidence that closed tracheal suction systems (TSS) prevent ventilator-associated pneumonia (VAP).

Methods: We searched PubMed and Cochrane databases to identify RCTs that compared closed with open TSS for the management of mechanically ventilated (MV) patients.

Results: Nine RCTs were included in the meta-analysis. There was no difference on VAP incidence between patients managed with closed and open TSS [odds ratio (OR) = 0.96, 95% confidence intervals (CI) 0.72–1.28]. There was no heterogeneity among the eligible trials (I2= 0, 95% CI 0–0.65). The compared groups did not differ on mortality (OR= 1.04, 95% CI 0.78–1.39) and on intensive care unit (ICU) length of stay (one RCT: 12.3 ± 1.1 vs 11.5 ± 1.4 days, and the other RCT: 15.6 ± 13.4 vs 19.9 ± 16.7 days). Suctioning with closed systems was associated with longer MV duration (weighted mean differences: 0.65 days, 95% CI, 0.28–1.03) and higher colonisation of the respiratory tract (OR= 2.88, 95% CI 1.50–5.52) than open TSS.

Discussion: The available evidence suggests that closed as opposed to open TSS usage did not provide any benefit on VAP incidence, mortality, or ICU stay of MV patients.

Session Details

Date: 19/04/2008
Time: 00:00-00:00
Session name: 18th European Congress of Clinical Microbiology and Infectious Diseases
Location: Barcelona, Spain
Presentation type:
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