Closed tracheal suction systems for prevention of ventilator-associated pneumonia
Abstract number: P816
Siempos I., Vardakas K., Falagas M.
Objective: By meta-analysis of randomised controlled trials (RCTs), we assessed the evidence that closed tracheal suction systems (TSS) prevent ventilator-associated pneumonia (VAP).
Methods: We searched PubMed and Cochrane databases to identify RCTs that compared closed with open TSS for the management of mechanically ventilated (MV) patients.
Results: Nine RCTs were included in the meta-analysis. There was no difference on VAP incidence between patients managed with closed and open TSS [odds ratio (OR) = 0.96, 95% confidence intervals (CI) 0.721.28]. There was no heterogeneity among the eligible trials (I2= 0, 95% CI 00.65). The compared groups did not differ on mortality (OR= 1.04, 95% CI 0.781.39) and on intensive care unit (ICU) length of stay (one RCT: 12.3 ± 1.1 vs 11.5 ± 1.4 days, and the other RCT: 15.6 ± 13.4 vs 19.9 ± 16.7 days). Suctioning with closed systems was associated with longer MV duration (weighted mean differences: 0.65 days, 95% CI, 0.281.03) and higher colonisation of the respiratory tract (OR= 2.88, 95% CI 1.505.52) than open TSS.
Discussion: The available evidence suggests that closed as opposed to open TSS usage did not provide any benefit on VAP incidence, mortality, or ICU stay of MV patients.
|Session name:||18th European Congress of Clinical Microbiology and Infectious Diseases|
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