Urinary tract infection in asymptomatic jaundiced newborns

Abstract number: 1734_223

Mosayebi Z., Movahhedian A.

Objectives: The incidence of neonatal urinary tract infection (UTI) varies from 0.1% to 1% of all infants. Previous studies have noted that jaundice may be one of the first signs of bacterial infection in infants. The aim of this study was to evaluate the incidence of UTI in asymptomatic jaundiced newborns admitted for evaluation and treatment of indirect hyperbilirubinaemia in Beheshti Hospital (Kashan-Iran) during 15 months period.

Methods: We prospectively investigated 377 asymptomatic jaundiced newborns during the study period.A bilirubin work up as well as urinanalysis and urine culture by bag were performed for all patients. If the urine culture was positive, a suprapubic aspiration were done. Newborns with positive urine culture by suprapubic aspiration results were accepted as having UTI.

Results: Of 377 newborns with indirect hyperbilirubinaemia UTI was diagnosed in 13 cases (3.4%). Isolated organisms included Escherichia coli (70%), Klebsiella pneumoniae (23%) and Staphylococcus epidermidis (7%). UTI was more common in male and term newborns.

The mean serum bilirubin level of neonates with UTI was 19.4 mg/dl (SD = 3.2). Eight newborns with UTI had bilirubin level greater than 20 mg/dl.

Patient with the onset of jaundice after 7 days of age had a higher incidence of UTI.

Conclusion: UTI can be associated with neonatal indirect hyperbilirubinaemia. We recommend that urine culture be included as part of the evaluation in asymptomatic jaundiced newborns.

Session Details

Date: 31/03/2007
Time: 00:00-00:00
Session name: European Society of Clinical Microbiology and Infectious Diseases
Location: ICC, Munich, Germany
Presentation type:
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