Genotype of hepatitis C virus in Libya
Abstract number: 1734_197
Dow M., Alamari A., Elahwel A., Abdulla A., Albagar S., Ranganathan A.
Objective: Information about the incidence of genotypes in hepatitis C virus (HCV) infected patients in Libya is limited. Aim of the study to investigate the incidence of hepatitis C virus (HCV) genotypes in Sirte, Libya.
Method: Sera were obtained from 78 (48 males and 30 females) Libyan patients who were anti-HCV positive by ELISA (Enzyme-Linked Immunosorbent Assay). The studied patients ranged in age from 20 to 80 years old. HCV RNA was genotyped by PCR (Cobas Amplicor Roche, Switzerland).
Results: In this study, half of the 78 patients (54%) were infected with genotype 4. Genotype 1 was the second most dominant genotype with a prevalence of 11.5%. Genotypes 2 and 36 were found in 6.4 and 7.6% of the patients, respectively.
Conclusion: in this study, most of the Libyan isolates were genotype 4. The higher presence of genotype 4 in the Libya may indicate a larger immigration from neighbouring country (Egypt) and Central African countries, where genotype 4 is predominant. Few of the Libyan isolates were closely related to the European ones where the majority of patients are infected with genotype 1, 2 or 3.
|Session name:||European Society of Clinical Microbiology and Infectious Diseases|
|Location:||ICC, Munich, Germany|
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