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Genotype of hepatitis C virus in Libya

Abstract number: 1734_197

Dow M., Alamari A., Elahwel A., Abdulla A., Albagar S., Ranganathan A.

Objective: Information about the incidence of genotypes in hepatitis C virus (HCV) infected patients in Libya is limited. Aim of the study to investigate the incidence of hepatitis C virus (HCV) genotypes in Sirte, Libya.

Method: Sera were obtained from 78 (48 males and 30 females) Libyan patients who were anti-HCV positive by ELISA (Enzyme-Linked Immunosorbent Assay). The studied patients ranged in age from 20 to 80 years old. HCV RNA was genotyped by PCR (Cobas Amplicor Roche, Switzerland).

Results: In this study, half of the 78 patients (54%) were infected with genotype 4. Genotype 1 was the second most dominant genotype with a prevalence of 11.5%. Genotypes 2 and 3–6 were found in 6.4 and 7.6% of the patients, respectively.

Conclusion: in this study, most of the Libyan isolates were genotype 4. The higher presence of genotype 4 in the Libya may indicate a larger immigration from neighbouring country (Egypt) and Central African countries, where genotype 4 is predominant. Few of the Libyan isolates were closely related to the European ones where the majority of patients are infected with genotype 1, 2 or 3.

Session Details

Date: 31/03/2007
Time: 00:00-00:00
Session name: European Society of Clinical Microbiology and Infectious Diseases
Subject:
Location: ICC, Munich, Germany
Presentation type:
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