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Trends in antibiotic consumption in 5 Hellenic hospitals over a three-year period: results of the Hellenic Network for Nosocomial Antibiotic Consumption for the years 2003–2004–2005

Abstract number: 1734_82

Katsimpris K., Lelekis M., Loupa C., Tzannou I., Xylomenos G., Anitsakis C., Provis A., Efthymiou C., Gargalianos P.

Objectives: Hellenic Network for Nosocomial Antibiotic Consumption (HENNAC) is a network of 5 hospitals located in different parts of Greece, established for monitoring antibiotic consumption in Hellenic hospitals: ``G. Gennimatas'' General Hospital (GGH) of Athens (tertiary care, 700 beds), ``A. Fleming'' General Hospital (AFH) of Athens (300 beds), ``A. Papandreou'' General Hospital of Rhodes Island (RH, Southeastern Greece, 335 beds), ``Vostaneio'' General Hospital of Lesvos Island (LH, Northeastern Greece, 225 beds) and Zakynthos Island General Hospital (ZH, Western Greece, 125 beds).

Methods: The antibiotic consumption for the years 2003, 2004 and 2005 was calculated in DDDs per 1000 patient days (ABC calc 3.0).

Results: Compared to 2003, in 2005: (1) Total consumption increased in AFH (from 710 to 892), LH (from 1148 to 1299) and GGH (from 906 to 1117), decreased in ZH (from 1268 to 1060) and remained practically stable in RH (from 1371 to 1346). (2) Concerning consumption of major classes of antibiotics: A. Penicillins: increase in AFH and LH, stable in RH and decrease in ZH, GGH. B. Cephalosporins + aztreonam: increase in AFH, RH, decrease in GGH and stable in ZH, LH. C. Carbapenems: increase in all but LH where it was stable. D. Penicillins+inhibitors: increase in RH, LH, GGH, decrease in AFH, ZH. E. Aminoglycosides: increase in LH, GGH, stable in AFH, decrease in ZH and RH. F. Macrolides: increase in all but ZH. G. Glycopeptides: increase in all but GGH. H. Quinolones: increase in AFH, GGH, decrease in ZH, RH, LH. (3) Cephalosporins + aztreonam were the most popular antibiotics for the year 2005 (being first in 3 hospitals and second in other 2) followed by penicillins + inhibitors, while for the year 2003 exactly the opposite was the case.

Conclusions: A. While there is no uniform trend for antibiotic consumption in the hospitals of the network, total consumption is high in all of them, compared to hospitals of other European countries. B. Cephalosporins + aztreonam are now the most popular antibiotic class. C. Further studies are under way in order to explain local peculiarities in antibiotic prescribing in the hospitals of the network.

Session Details

Date: 31/03/2007
Time: 00:00-00:00
Session name: European Society of Clinical Microbiology and Infectious Diseases
Subject:
Location: ICC, Munich, Germany
Presentation type:
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