Antibiotic susceptibility of Yersinia strains in Kazakhstan

Abstract number: 1734_51

Nekrassova L., Meka-Mechenko T., Aikimbayev A., Temiralieyva G.

Objectives: Study of the regional peculiarities of sensitivity to antibiotics of Yersinia strains may to serve the considerable requisite for the rational using of antibacterial preparations in the treatment of Yersinioses.

Methods: The method of serial dilution on the agar was applied to comparative assay of antibiotic sensitivity. It was determined antibiotic susceptibility 200 strains different kinds of Yersinia.

Results: High sensitivity Y. pseudotuberculosis, Y. enterocolitica, Y. kristensenii, Y. intermedia, Y. frederiksenii to streptomycin and to a lesser degree to chloramphenicol is established. On the literary data of significant distinctions in sensitivity Yersinia to these antibiotics is not present. Probably, this fact also specifies territorial feature of the activators of Yersinioses circulating in Kazakhstan. Now there is no though some an appreciable tendency to development resistance to streptomycin, chloramphenicol and tetracycline in strains of Y. pseudotuberculosis, Y. enterocolitica.

However, the quantity resistant forms to these antibiotics in strains, isolated in natural landscapes are a little bit lower. In number of areas of Kazakhstan which anthropogenous influence has affected are found out in strains of Y. pseudotuberculosis and Y. enterocolitica with resistance to streptomycin, tetracycline. These strains were isolated from wild rodents.

Other species of Yersinia (Y. kristensenii, Y. frederiksenii, Y. intermedia) were differed by the big number of resistance forms, irrespective of source of isolation. Occurrence of a plenty resistance to streptomycin, chloramphenicol and tetracycline forms of these species Yersinia can be specific and territorial features of these species. It is impossible to exclude penetration of resistance variants in the natural foci from anthropurgical.

Conclusion: There are distinctions by quantity antibiotics resistance forms in epizootic foci exposed and not exposed anthropogenous influence. In the foci exposed to anthropogenous influence the quantity of such strains is much higher.

Session Details

Date: 31/03/2007
Time: 00:00-00:00
Session name: European Society of Clinical Microbiology and Infectious Diseases
Location: ICC, Munich, Germany
Presentation type:
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