Occurrence of CTX-M-3 extended-spectrum b-lactamase producing Salmonella Brandenburg in Bulgaria
Abstract number: 1734_39
Petrov P., Asseva G., Kantardjiev T., Padeshky P., Vlahova N., Ivanov I., Ivanov A., Nikolova M.
Objectives: to study the genetic profile and resistance to antibiotics of a rare serotype of Salmonella causing a cluster of cases among infants and children in Bulgaria.
Methods: nine strains of Salmonella Brandenburg were isolated from infants and children with acute enterocolitis in the beginning of 2005. Culture, identification, serotyping and antimicrobial susceptibility testing to fourteen antibiotics have been performed. PCR with primers detecting bla-CTX-M genes and PFGE after restriction with XbaI were applied.
Results: a single PFGE type of strains confirmed the occurrence of a cluster of cases caused by Salmonella Brandenburg among infants and children. The strain was found to be multidrug-resistant. It produced a CTX-M-3 extended-spectrum b-lactamase.
Conclusion: our findings proved the ethiological role of an unique genetic variant of Salmonella Brandenburg in a cluster of cases among infants and children. This is the first report for Bulgaria of Salmonella Brandenburg producing a CTX-M-3 extended-spectrum b-lactamase.
|Session name:||European Society of Clinical Microbiology and Infectious Diseases|
|Location:||ICC, Munich, Germany|
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