Procalcitonin as a parameter for the early recognition of severe bacterial infections

Abstract number: 1733_1240

Georgouli A., Chinou E., Manavoglou D., Ntavlouros P., Skouteli E., Golemati P.

Objectives: The aim of our study was to confirm the diagnostic value of procalcitonin (PCT) levels in the discrimination between severe bacterial infections and other conditions such as localised infections, superficial bacterial colonisation or viral infections.

Methods: We examined 166 patients divided into four groups: control group (n = 85, patients with no sign of infection); patients with confirmed sepsis (n = 12); patients with localised infections (n = 32); patients with bacterial colonisation (n = 26); and patients with confirmed viral infection (n = 11). Plasma PCT levels were determined by an immunochromatographic test for the semi-quantitative detection of PCT (normal range of PCT values <0.5 ng/mL).

Results: The following results were obtained:

- Control group (n = 85): PCT levels <0.5 ng/mL.

- Sepsis (n = 12): PCT levels ≥10.0 ng/mL.

- Localised infection (n = 32): PCT levels 0.5–2.0 ng/mL.

- Bacterial colonisation (n = 26): PCT levels 0.0–2.0 ng/mL.

- Viral infection (n = 11): PCT levels 0.0–0.5 ng/mL.

Conclusions: Our study confirmed that PCT is a sensitive parameter that is higly elevated only in severe bacterial infections as opposed to viral infections, localised infections and superficial bacterial colonisation.

Session Details

Date: 31/03/2007
Time: 00:00-00:00
Session name: European Society of Clinical Microbiology and Infectious Diseases
Location: ICC, Munich, Germany
Presentation type:
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