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Study of immunity level to measles and mumps in women of reproductive age in Northern Greece

Abstract number: 1733_1057

Fylaktou A., Goutaki M., Kalamitsou S., Haidopoulou A., Atmatzidis G., Papadopoulou E.

Objectives: The aim of our study was to examine the immunity status to measles and mumps in women of reproductive age.

Methods: Our specimen consists of 198 women between 16–45 years old who were examined in our hospital during the years 2004–2006. Our specimen was divided in two groups according to vaccination status. IgG and IgM antibodies titers for measles and mumps was determined in blood serum by Elisa Virotech (genzyme diagnostics) semiquantitive method.

Results: 91.9% of women are immune to measles whereas for mumps the percentage presents significant decrease to 75.76%. In the overwhelming majority the immunity is due to infection. This is justified because the MMR vaccine was introduced to the National Immunization Program at 1989 while previously the immunisation rate either with MMR (after the mid seventies) or with the monovalent vaccines for measles and mumps was less than 30%.

 IgG+IgG-
n(%)n(%) 
Measles
Group A (after vaccination)29(14.65)0(0)
Group B (no vaccination)163(77.27)16(8.08)
Total182(91.92)16(8.08)
MUMPS
Group A (after vaccination)29(14.65)0(0)
Group B (no vaccination)121(61.11)48(24.24)
Total150(75.76)48(24.24)

Conclusion: A significant percentage of women of reproductive age (24.24% of specimen) is susceptible to mumps. Although these women are protected by the community's immunity it would be wise to be alert since mumps during the first trimester of pregnancy is associated with an increased rate of spontaneous abortion. Also we note that infants of these mothers will be at high risk for serious infection from mumps and measles virus with an increased frequency for complications, having obtained no immunity by transported maternal IgG.

Session Details

Date: 31/03/2007
Time: 00:00-00:00
Session name: European Society of Clinical Microbiology and Infectious Diseases
Subject:
Location: ICC, Munich, Germany
Presentation type:
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