Serum copper and zinc levels in patients with brucellosis

Abstract number: 1733_1014

Hosoglu S., Ayaz C., Geyik M.F., Ustun C., Tegin I.

Objective: The aim of this study is to compare the serum Copper (Cu) and Zinc (Zn) levels of patients with brucellosis and healthy individuals.

Material and Methods: In this study, 43 patients with brucellosis, and 32 healthy individuals in the control group were included. From totally 75 individuals, 5 mL of venous blood was taken after fasting 10 hours at night. Serum samples were decomposed by centrifugeting at 5,200 turn for 5 minutes. Serum samples were diluted with deionised water. Cu and Zn levels were measured in all serum samples by using Unicam 929 Atomic Absorption Spectrophotometer. All data entry and analysis were performed using SPSS 10.0 for Windows Version programme.

Results: The average age of 43 patients with brucellosis was 39 years; 21 were males (49%), 22 were females (51%). The average age of 32 healthy individuals was 32 years; 16 were males (50%), 16 were females (50%). Serum Cu and Zn levels of patients with brucellosis were found to be 89 mg/dL and 38.6 mg/dL, respectively. Serum Cu and Zn levels of healthy individuals were found to be 57.2 mg/dL and 55.9 mg/dL respectively. A statistically significant (p = 0.0001) increase at serum Cu levels and decrease in Zn levels of patient with brucellosis were detected, when compared with the control group.

Conclusion: The current evidence suggests that, Cu and Zn levels may be helpful as indicator in the course of brucellosis.

Session Details

Date: 31/03/2007
Time: 00:00-00:00
Session name: European Society of Clinical Microbiology and Infectious Diseases
Location: ICC, Munich, Germany
Presentation type:
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