Vaccination of healthcare workers against hepatitis B virus in a teaching hospital

Abstract number: 1733_575

Ataman Hatipoglu C., Yetkin M.A., Ergin F., Ipekkan K., Erdinc F.S., Bulut C., Tulek N., Demir G., Yigit Y., Demiroz A.P.

Objectives: Hepatitis B virus infection which can be prevented by active immunisation is one of the common health problems among the healthcare workers (HCW). The aim of this study was to vaccinate our HCWs in order to protect them against hepatitis B virus.

Methods: A total of 1009 HCWs who were working in Ankara Teaching and Research Hospital during January 2002-June 2006 were included into the study. HBsAg and antiHBs results, demographic data (gender, age, occupation and department) and immune status against hepatitis B virus were recorded for each HCW. HCWs that were negative for HBsAg and antiHBs were included into the vaccination programme.

Results: Among 1009 HCWs, 448 were male (44.4%), 561 female (55.6%) and the mean age was 32.02±7.74 years. Of the HCWs, 209 were working as doctors (20.7%), 246 as nurses (24.4%), 322 as domestic workers (31.9%) and 232 (23.0%) as other works (laboratory technician, radiology technician, officer, etc). Thirty-one percent of HCWs were working in the surgical departments whereas 20.6% of them in internal medicine departments. The rest of them were working in laboratories, emergency department, outpatient clinics and various other parts of the hospital with a rate of 8.4%, 7.4%, 7.3% and 25.5%, respectively. HBsAg was negative in all HCWs. AntiHBs was positive in 439 (43.5%) and negative in 570 (56.5%). A total of 570 HCWs were included in the vaccination programme. One hundred and fifteen (20.2%) were vaccinated with three-dose regimen in 0, 1 and 6 months, 349 (61.2%) with four-dose regimen in 0, 1, 2 and 12 months and 106 (18.6%) with single booster dose with yeast derived hepatitis B vaccine (Euvax-B, LG Chemical, S. Corea). Four hundred and sixty-nine of 1009 HCWs had a history of vaccination before, 170 (36.3%) of them had negative value of antiHBs at the time of the study. These 170 HCWs were vaccinated with a single dose hepatitis B vaccine. One hundred and six of them became positive for anti HBs after this vaccination. A complete vaccination schedule was applied to the remaining 64 HCWs who were negative after a single dose. Three hundred and sixty HCWs (63.1%) were compatible with the vaccination programme whereas 210 (36.9%) of them were incompatible.

Conclusion: We think that systematic surveillance and vaccination against hepatitis B will reduce the risk of transmission of this infection to the HCWs.

Session Details

Date: 31/03/2007
Time: 00:00-00:00
Session name: European Society of Clinical Microbiology and Infectious Diseases
Location: ICC, Munich, Germany
Presentation type:
Back to top