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Epidemiological characteristics of nosocomial blood infections at a clinical centre, Belgrade, Serbia in 2005

Abstract number: 1733_453

Jovanovic B., Mioljevic V., Jovanovic S., Mazic N., Palibrk I.

Introduction: Nosocomial bloodstream infections (BSI) represent actual and one of the most severe medical problems due to their frequency, prolonged hospitalisation and increase of medical costs. Their incidence varies depending on the characteristics of the observed patients and department, ranging between 1.3 and 18.4 per 1000 patient days. Major causes of BSI include coagulase-negative staphylocci(CNS), Staphylococcus aureus, Enterococcus spp. and Candida spp.

Purpose: Determining of BSI incidence and distribution of BSI causes in percentages in patients hospitalised for more than 48 hours at the Institute of Digestive Diseases in 2005.

Methods: BSI incidence is calculated using Atlanta CDC methodology. Cultivation, isolation, identification and susceptibility tests of the causative organisms obtained from the patient material was carried out using standard microbiological methods in the Microbiological Laboratory within the Emergency Center of the Clinical Center of Serbia.

Results: BSI incidence at the Institute of Digestive Surgery was 5.76 per 1000 patient days. One third (28%) of all blood infections verified in the laboratory was caused by CNS, followed by Klebsiella spp. (14%), Staphylococcus aureus and Candida spp. (12.5%). Methicillin resistance was evidenced in 80% of CNS isolates and 90% of Staphylococcus aureus isolates. ESBL was produced by 18% of Klebsiella spp. isolates.

Conclusion: The incidence of BSI recorded at the Institute of Digestive Diseases in 2005 was 5.76 per 1000 patient days. One third of all blood infections verified in the laboratory at the Institute during 2005, was caused by CNS, followed by Klebsiella spp., Staphylococcus aureus and Candida spp. All the isolates show high degree of resistance to antimicrobial drugs. Epidemiological surveillance of BSI enables insight into epidemiology of BSI, monitoring of resistance of causative organisms and application of the specific preventive measures against the infections.

Session Details

Date: 31/03/2007
Time: 00:00-00:00
Session name: European Society of Clinical Microbiology and Infectious Diseases
Subject:
Location: ICC, Munich, Germany
Presentation type:
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